Putative ADP-ribosylation factor-like 2, arl2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ADP-ribosylation factor-like 2, arl2, putative

Species:

Leishmania major

UniProt:

E9AEJ0_LEIMA

TriTrypDb:

LmjF.35.0130 , LMJLV39_350006300 , LMJSD75_350006400

Length:

186

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005856	cytoskeleton	5	2
GO:0015630	microtubule cytoskeleton	6	2
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9AEJ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AEJ0

Function

Biological processes
Term	Name	Level	Count
GO:0000281	mitotic cytokinesis	4	2
GO:0000910	cytokinesis	3	2
GO:0006457	protein folding	2	2
GO:0009987	cellular process	1	2
GO:0022402	cell cycle process	2	2
GO:0061640	cytoskeleton-dependent cytokinesis	4	2
GO:1903047	mitotic cell cycle process	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0003924	GTPase activity	7	12
GO:0005488	binding	1	12
GO:0005525	GTP binding	5	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0019001	guanyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032561	guanyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	82	86	PF00656	0.279
CLV_NRD_NRD_1	11	13	PF00675	0.332
CLV_PCSK_KEX2_1	11	13	PF00082	0.313
CLV_PCSK_KEX2_1	151	153	PF00082	0.279
CLV_PCSK_KEX2_1	180	182	PF00082	0.503
CLV_PCSK_PC1ET2_1	11	13	PF00082	0.313
CLV_PCSK_PC1ET2_1	151	153	PF00082	0.294
CLV_PCSK_PC1ET2_1	180	182	PF00082	0.397
DOC_MAPK_gen_1	148	156	PF00069	0.258
DOC_MAPK_gen_1	8	19	PF00069	0.313
DOC_MAPK_MEF2A_6	12	21	PF00069	0.313
DOC_USP7_MATH_1	116	120	PF00917	0.279
DOC_USP7_UBL2_3	35	39	PF12436	0.272
DOC_USP7_UBL2_3	9	13	PF12436	0.313
DOC_WW_Pin1_4	131	136	PF00397	0.313
DOC_WW_Pin1_4	42	47	PF00397	0.319
LIG_14-3-3_CanoR_1	58	63	PF00244	0.373
LIG_14-3-3_CterR_2	181	186	PF00244	0.517
LIG_Clathr_ClatBox_1	141	145	PF01394	0.431
LIG_FHA_1	28	34	PF00498	0.279
LIG_FHA_1	39	45	PF00498	0.279
LIG_FHA_1	59	65	PF00498	0.158
LIG_FHA_1	82	88	PF00498	0.311
LIG_LIR_Nem_3	75	80	PF02991	0.297
LIG_NRBOX	105	111	PF00104	0.279
LIG_PCNA_PIPBox_1	70	79	PF02747	0.279
LIG_PCNA_yPIPBox_3	70	78	PF02747	0.279
LIG_Pex14_1	77	81	PF04695	0.279
LIG_Rb_LxCxE_1	95	113	PF01857	0.343
LIG_SH2_STAT5	183	186	PF00017	0.479
LIG_SH2_STAT5	80	83	PF00017	0.294
LIG_SUMO_SIM_par_1	140	146	PF11976	0.375
LIG_TRAF2_1	134	137	PF00917	0.338
LIG_UBA3_1	120	126	PF00899	0.279
LIG_UBA3_1	20	29	PF00899	0.212
LIG_UBA3_1	3	11	PF00899	0.306
MOD_CK1_1	160	166	PF00069	0.329
MOD_CK1_1	42	48	PF00069	0.279
MOD_CK1_1	72	78	PF00069	0.294
MOD_CK2_1	131	137	PF00069	0.402
MOD_Cter_Amidation	149	152	PF01082	0.279
MOD_GlcNHglycan	159	162	PF01048	0.293
MOD_GSK3_1	38	45	PF00069	0.335
MOD_NEK2_1	50	55	PF00069	0.287
MOD_NEK2_2	69	74	PF00069	0.281
MOD_Plk_1	39	45	PF00069	0.280
MOD_Plk_4	116	122	PF00069	0.305
MOD_Plk_4	2	8	PF00069	0.313
MOD_Plk_4	39	45	PF00069	0.215
MOD_ProDKin_1	131	137	PF00069	0.313
MOD_ProDKin_1	42	48	PF00069	0.319
TRG_DiLeu_BaEn_1	105	110	PF01217	0.279
TRG_DiLeu_BaEn_1	137	142	PF01217	0.424
TRG_DiLeu_BaEn_1	16	21	PF01217	0.313
TRG_DiLeu_BaLyEn_6	95	100	PF01217	0.365
TRG_NLS_MonoExtC_3	7	12	PF00514	0.313

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3Q3	Leptomonas seymouri	41%	98%
A0A0N0P4P7	Leptomonas seymouri	33%	100%
A0A0N0P633	Leptomonas seymouri	43%	100%
A0A0N0P8D4	Leptomonas seymouri	45%	100%
A0A0N0P8Z3	Leptomonas seymouri	43%	100%
A0A0N1HS40	Leptomonas seymouri	37%	100%
A0A0N1HTN6	Leptomonas seymouri	42%	98%
A0A0N1I3A9	Leptomonas seymouri	35%	100%
A0A0N1I556	Leptomonas seymouri	41%	100%
A0A0N1I6N0	Leptomonas seymouri	92%	100%
A0A0N1IKF2	Leptomonas seymouri	35%	95%
A0A0N1PD39	Leptomonas seymouri	36%	100%
A0A0S4IQT8	Bodo saltans	40%	99%
A0A0S4IS60	Bodo saltans	35%	100%
A0A0S4J2X3	Bodo saltans	35%	100%
A0A0S4J3L7	Bodo saltans	34%	100%
A0A0S4J5U8	Bodo saltans	31%	98%
A0A0S4J8H6	Bodo saltans	41%	100%
A0A0S4JK65	Bodo saltans	80%	100%
A0A0S4JQ13	Bodo saltans	34%	95%
A0A0S4KJ70	Bodo saltans	42%	87%
A0A0S4KKS9	Bodo saltans	39%	100%
A0A0S4KLN8	Bodo saltans	28%	78%
A0A1X0NKM5	Trypanosomatidae	81%	100%
A0A1X0NKZ8	Trypanosomatidae	36%	96%
A0A1X0NLB1	Trypanosomatidae	40%	98%
A0A1X0NLP5	Trypanosomatidae	47%	100%
A0A1X0NT19	Trypanosomatidae	39%	98%
A0A1X0NZX3	Trypanosomatidae	47%	100%
A0A1X0P0A2	Trypanosomatidae	33%	100%
A0A1X0P0D4	Trypanosomatidae	32%	96%
A0A1X0P1V3	Trypanosomatidae	29%	80%
A0A1X0P1Y5	Trypanosomatidae	36%	100%
A0A1X0P2L5	Trypanosomatidae	35%	96%
A0A1X0P5P0	Trypanosomatidae	42%	100%
A0A1X0P676	Trypanosomatidae	36%	97%
A0A1X0P850	Trypanosomatidae	29%	67%
A0A221LG87	Leishmania donovani	35%	95%
A0A3Q8IDS2	Leishmania donovani	29%	100%
A0A3Q8IFX9	Leishmania donovani	35%	100%
A0A3R7KSW8	Trypanosoma rangeli	31%	100%
A0A3R7L2X6	Trypanosoma rangeli	38%	100%
A0A3R7MW79	Trypanosoma rangeli	39%	98%
A0A3R7NC73	Trypanosoma rangeli	39%	98%
A0A3R7NMH3	Trypanosoma rangeli	33%	98%
A0A3R7RGT1	Trypanosoma rangeli	44%	100%
A0A3S5H598	Leishmania donovani	36%	100%
A0A3S5H5A9	Leishmania donovani	40%	98%
A0A3S5IQP0	Trypanosoma rangeli	80%	100%
A0A3S5ISB1	Trypanosoma rangeli	34%	100%
A0A3S7WU76	Leishmania donovani	43%	99%
A0A3S7X4X3	Leishmania donovani	41%	100%
A0A3S7X8N3	Leishmania donovani	98%	100%
A0A3S7XC57	Leishmania donovani	45%	100%
A0A422MYB1	Trypanosoma rangeli	40%	100%
A0A422MZM4	Trypanosoma rangeli	32%	96%
A0A422NNC6	Trypanosoma rangeli	37%	97%
A0A422NRN0	Trypanosoma rangeli	45%	100%
A0A422NW53	Trypanosoma rangeli	38%	100%
A1CRG9	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	34%	98%
A1D4D1	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	35%	98%
A3LTA2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	32%	98%
A4H3V3	Leishmania braziliensis	36%	100%
A4H3W8	Leishmania braziliensis	39%	98%
A4H449	Leishmania braziliensis	35%	95%
A4H8R6	Leishmania braziliensis	30%	100%
A4H8V3	Leishmania braziliensis	42%	99%
A4HH98	Leishmania braziliensis	44%	100%
A4HJL1	Leishmania braziliensis	41%	100%
A4HJR7	Leishmania braziliensis	41%	100%
A4HM52	Leishmania braziliensis	94%	100%
A4HQE3	Leishmania braziliensis	47%	100%
A4HS29	Leishmania infantum	35%	100%
A4HS43	Leishmania infantum	40%	98%
A4HSC6	Leishmania infantum	35%	95%
A4HX34	Leishmania infantum	29%	100%
A4HX72	Leishmania infantum	43%	99%
A4I4E4	Leishmania infantum	44%	100%
A4I5R5	Leishmania infantum	35%	100%
A4I784	Leishmania infantum	41%	100%
A4IAR4	Leishmania infantum	98%	100%
A4IE34	Leishmania infantum	45%	100%
A5DR82	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	33%	98%
A5E5G3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	32%	98%
A6NH57	Homo sapiens	32%	100%
A8ISN6	Chlamydomonas reinhardtii	52%	100%
B5FYQ0	Taeniopygia guttata	50%	100%
C9ZL19	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	100%
C9ZPY6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	96%
C9ZR33	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZTU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	98%
C9ZVV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	98%
C9ZY21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	96%
C9ZY41	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	98%
C9ZZD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZZD6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
D0A2E8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	78%	100%
D0A2Q7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	69%
D0A3V1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	67%
E9ADU4	Leishmania major	44%	99%
E9AHL7	Leishmania infantum	42%	100%
E9AIU0	Leishmania braziliensis	35%	100%
E9AK16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9AK30	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9AKA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	95%
E9ALY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9AQU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9ARC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	99%
E9AU58	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	100%
E9B110	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B229	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B278	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9B5Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
F4IZ82	Arabidopsis thaliana	38%	100%
O00909	Dictyostelium discoideum	42%	100%
O04266	Brassica campestris	36%	96%
O04267	Brassica campestris	34%	95%
O04834	Arabidopsis thaliana	38%	96%
O08697	Rattus norvegicus	62%	100%
O23778	Catharanthus roseus	42%	100%
O45379	Caenorhabditis elegans	46%	100%
O48649	Salix bakko	43%	100%
O48920	Vigna unguiculata	43%	100%
O88848	Mus musculus	34%	100%
P0C583	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	35%	98%
P0C950	Aspergillus niger	34%	98%
P0C951	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	35%	98%
P0CM16	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	42%	100%
P0CM17	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	42%	100%
P0CR30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	35%	98%
P0CR31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	35%	98%
P0CT16	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	34%	98%
P0CT17	Magnaporthe oryzae (strain Y34)	34%	98%
P0DH91	Arabidopsis thaliana	43%	100%
P11076	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	100%
P18085	Homo sapiens	40%	100%
P19146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	100%
P20606	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	98%
P22274	Candida albicans (strain SC5314 / ATCC MYA-2876)	43%	100%
P25160	Drosophila melanogaster	40%	100%
P26990	Gallus gallus	41%	100%
P26991	Giardia intestinalis	42%	97%
P34212	Caenorhabditis elegans	39%	100%
P34727	Ajellomyces capsulatus	43%	100%
P36397	Arabidopsis thaliana	43%	100%
P36404	Homo sapiens	62%	100%
P36405	Homo sapiens	49%	100%
P36536	Mus musculus	31%	94%
P36579	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	100%
P37996	Rattus norvegicus	49%	100%
P38116	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	100%
P39110	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	97%
P40616	Homo sapiens	41%	100%
P40617	Homo sapiens	37%	93%
P40940	Arabidopsis thaliana	41%	100%
P40945	Drosophila melanogaster	41%	100%
P40946	Drosophila melanogaster	40%	100%
P40994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	100%
P49076	Zea mays	43%	100%
P49702	Gallus gallus	44%	100%
P49703	Homo sapiens	39%	93%
P51643	Xenopus laevis	42%	100%
P51644	Xenopus laevis	44%	100%
P51645	Xenopus laevis	40%	100%
P51646	Rattus norvegicus	37%	100%
P51821	Chlamydomonas reinhardtii	43%	100%
P51822	Daucus carota	43%	100%
P51823	Oryza sativa subsp. japonica	43%	100%
P51824	Solanum tuberosum	43%	94%
P52884	Solanum lycopersicum	36%	96%
P52885	Nicotiana tabacum	31%	94%
P56559	Homo sapiens	37%	97%
P61204	Homo sapiens	42%	100%
P61205	Mus musculus	42%	100%
P61206	Rattus norvegicus	42%	100%
P61207	Takifugu rubripes	42%	100%
P61208	Mus musculus	37%	97%
P61209	Drosophila melanogaster	43%	100%
P61210	Locusta migratoria	43%	100%
P61211	Mus musculus	41%	100%
P61212	Rattus norvegicus	41%	100%
P61213	Mus musculus	37%	93%
P61214	Rattus norvegicus	37%	93%
P61750	Mus musculus	41%	100%
P61751	Rattus norvegicus	41%	100%
P62330	Homo sapiens	40%	100%
P62331	Mus musculus	40%	100%
P62332	Rattus norvegicus	40%	100%
P78976	Hypocrea jecorina	35%	98%
P84077	Homo sapiens	42%	100%
P84078	Mus musculus	42%	100%
P84079	Rattus norvegicus	42%	100%
P84080	Bos taurus	42%	100%
P84081	Bos taurus	43%	100%
P84082	Rattus norvegicus	43%	100%
P84083	Rattus norvegicus	43%	100%
P84084	Mus musculus	43%	100%
P84085	Homo sapiens	43%	100%
P91924	Dugesia japonica	43%	100%
Q007T5	Sus scrofa	40%	100%
Q01474	Arabidopsis thaliana	35%	96%
Q01475	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	98%
Q02804	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	94%
Q06396	Oryza sativa subsp. japonica	43%	100%
Q06849	Drosophila melanogaster	59%	100%
Q09767	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	47%	100%
Q0CUN7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	35%	98%
Q0IIM2	Bos taurus	35%	100%
Q0P5N6	Homo sapiens	31%	94%
Q0UKC0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	34%	100%
Q0VC18	Bos taurus	39%	93%
Q10943	Caenorhabditis elegans	43%	100%
Q13795	Homo sapiens	38%	93%
Q18510	Caenorhabditis elegans	31%	98%
Q19705	Caenorhabditis elegans	56%	100%
Q1MTE5	Danio rerio	49%	100%
Q1ZXA5	Dictyostelium discoideum	30%	100%
Q20758	Caenorhabditis elegans	40%	100%
Q23445	Caenorhabditis elegans	31%	96%
Q25761	Plasmodium falciparum (isolate NF54)	43%	100%
Q2HA55	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	35%	98%
Q2KI07	Bos taurus	28%	100%
Q2KJ96	Bos taurus	37%	100%
Q2TA37	Bos taurus	62%	100%
Q2TBW6	Bos taurus	50%	100%
Q2YDM1	Bos taurus	41%	100%
Q32LJ2	Bos taurus	36%	93%
Q3SXC5	Mus musculus	37%	97%
Q3SZF2	Bos taurus	43%	100%
Q3T0D7	Bos taurus	32%	94%
Q3T0M9	Bos taurus	37%	93%
Q3T0T7	Bos taurus	34%	94%
Q4P0I7	Ustilago maydis (strain 521 / FGSC 9021)	33%	98%
Q4Q0D7	Leishmania major	44%	100%
Q4Q5Y0	Leishmania major	41%	100%
Q4Q756	Leishmania major	35%	100%
Q4QEJ1	Leishmania major	43%	99%
Q4QEM9	Leishmania major	29%	100%
Q4QJK0	Leishmania major	35%	95%
Q4R4S4	Macaca fascicularis	29%	100%
Q4R5P2	Macaca fascicularis	42%	100%
Q4WJS7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	35%	98%
Q52NJ3	Sus scrofa	32%	94%
Q52NJ4	Sus scrofa	49%	100%
Q54HK2	Dictyostelium discoideum	38%	98%
Q54I24	Dictyostelium discoideum	33%	86%
Q54JJ3	Dictyostelium discoideum	36%	98%
Q54K69	Dictyostelium discoideum	24%	94%
Q54R04	Dictyostelium discoideum	33%	100%
Q54UF1	Dictyostelium discoideum	54%	100%
Q54V41	Dictyostelium discoideum	37%	99%
Q54V47	Dictyostelium discoideum	38%	99%
Q54Y14	Dictyostelium discoideum	30%	96%
Q54YV7	Dictyostelium discoideum	21%	95%
Q559R0	Dictyostelium discoideum	31%	99%
Q55AD9	Dictyostelium discoideum	37%	100%
Q58DI9	Bos taurus	42%	100%
Q59S78	Candida albicans (strain SC5314 / ATCC MYA-2876)	31%	98%
Q5BGB9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	98%
Q5BK71	Rattus norvegicus	43%	100%
Q5E9I6	Bos taurus	42%	100%
Q5EA19	Bos taurus	33%	92%
Q5HZY2	Rattus norvegicus	32%	94%
Q5M9P8	Danio rerio	36%	100%
Q5PYH3	Sus scrofa	33%	94%
Q5R4G5	Pongo abelii	34%	100%
Q5R548	Pongo abelii	32%	94%
Q5R579	Pongo abelii	38%	93%
Q5R5P7	Pongo abelii	42%	100%
Q5R6E7	Pongo abelii	28%	100%
Q5RCF1	Pongo abelii	40%	100%
Q5RCQ6	Pongo abelii	43%	100%
Q5REU3	Pongo abelii	39%	93%
Q5RFN0	Pongo abelii	33%	91%
Q5UQ27	Acanthamoeba polyphaga mimivirus	28%	87%
Q5VLR7	Leishmania donovani	42%	100%
Q5ZKQ8	Gallus gallus	31%	100%
Q60Z38	Caenorhabditis briggsae	31%	98%
Q61LA8	Caenorhabditis briggsae	42%	100%
Q627K4	Caenorhabditis briggsae	55%	100%
Q63055	Rattus norvegicus	38%	93%
Q66HA6	Rattus norvegicus	29%	100%
Q6BVA7	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	32%	98%
Q6CB54	Yarrowia lipolytica (strain CLIB 122 / E 150)	34%	98%
Q6CWR7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	32%	98%
Q6FUZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	31%	98%
Q6IMM3	Leishmania major	42%	100%
Q6NZW8	Danio rerio	30%	100%
Q6P068	Mus musculus	36%	100%
Q6P3A9	Mus musculus	37%	100%
Q6P8C8	Xenopus tropicalis	31%	100%
Q755D7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	98%
Q75A26	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	43%	100%
Q76NM7	Plasmodium falciparum (isolate 3D7)	26%	90%
Q7KQL3	Plasmodium falciparum (isolate 3D7)	44%	100%
Q7RVM2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	43%	100%
Q80ZU0	Mus musculus	37%	100%
Q877B9	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	35%	98%
Q8BGR6	Mus musculus	33%	91%
Q8BSL7	Mus musculus	43%	100%
Q8BXL7	Mus musculus	38%	93%
Q8MQT8	Giardia intestinalis	29%	97%
Q8N4G2	Homo sapiens	38%	97%
Q8N8L6	Homo sapiens	37%	76%
Q8QHI3	Xenopus laevis	49%	100%
Q8VEH3	Mus musculus	30%	100%
Q8VY57	Arabidopsis thaliana	35%	100%
Q8W4C8	Arabidopsis thaliana	32%	100%
Q93Y31	Arabidopsis thaliana	36%	100%
Q94231	Caenorhabditis elegans	47%	100%
Q94650	Plasmodium falciparum	44%	100%
Q96361	Brassica rapa subsp. pekinensis	42%	100%
Q969Q4	Homo sapiens	41%	95%
Q96BM9	Homo sapiens	31%	100%
Q96KC2	Homo sapiens	38%	100%
Q99PE9	Mus musculus	39%	93%
Q9CQC9	Mus musculus	32%	94%
Q9CQW2	Mus musculus	29%	100%
Q9D0J4	Mus musculus	62%	100%
Q9D4P0	Mus musculus	38%	100%
Q9H0F7	Homo sapiens	34%	100%
Q9LQC8	Arabidopsis thaliana	43%	100%
Q9N6B0	Leishmania donovani	44%	100%
Q9NR31	Homo sapiens	32%	94%
Q9NVJ2	Homo sapiens	29%	100%
Q9NXU5	Homo sapiens	33%	91%
Q9P4C8	Komagataella phaffii (strain GS115 / ATCC 20864)	33%	98%
Q9QVY3	Cricetulus griseus	32%	94%
Q9QXJ4	Mus musculus	34%	77%
Q9SHU5	Arabidopsis thaliana	39%	91%
Q9U0T6	Leishmania major	40%	98%
Q9VHV5	Drosophila melanogaster	31%	100%
Q9WUL7	Mus musculus	49%	100%
Q9XZX2	Leishmania major	36%	100%
Q9Y689	Homo sapiens	37%	100%
Q9Y6B6	Homo sapiens	32%	94%
Q9Y7Z2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	43%	100%
Q9ZPX1	Arabidopsis thaliana	61%	100%
V5B891	Trypanosoma cruzi	40%	98%
V5DJR8	Trypanosoma cruzi	80%	100%