Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AED7_LEIMA

TriTrypDb:

LmjF.29.2750 , LMJLV39_290035800 , LMJSD75_290036100

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

E9AED7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AED7


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	68	70	PF00675	0.653
DEG_APCC_DBOX_1	21	29	PF00400	0.583
DOC_CYCLIN_yCln2_LP_2	41	47	PF00134	0.309
DOC_MAPK_gen_1	9	18	PF00069	0.593
LIG_LIR_Nem_3	30	34	PF02991	0.643
LIG_SH2_PTP2	48	51	PF00017	0.369
LIG_SH2_STAT5	48	51	PF00017	0.373
LIG_TYR_ITIM	46	51	PF00017	0.348
LIG_UBA3_1	1	9	PF00899	0.611
MOD_N-GLC_2	27	29	PF02516	0.396
MOD_NEK2_1	18	23	PF00069	0.644
MOD_PIKK_1	57	63	PF00454	0.366
MOD_PK_1	3	9	PF00069	0.552
MOD_PKB_1	63	71	PF00069	0.380
MOD_Plk_4	3	9	PF00069	0.569
TRG_ENDOCYTIC_2	48	51	PF00928	0.389
TRG_ER_diArg_1	13	16	PF00400	0.569
TRG_ER_diArg_1	20	23	PF00400	0.549


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILG8	Leptomonas seymouri	70%	99%
A0A0S4KE22	Bodo saltans	47%	88%
A0A3S7X2U0	Leishmania donovani	90%	100%
A4HHT2	Leishmania braziliensis	78%	100%
A4I4Z2	Leishmania infantum	90%	100%
E9ALE9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
V5BXH7	Trypanosoma cruzi	50%	100%