Putative helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative helicase

Gene product:

helicase, putative

Species:

Leishmania major

UniProt:

E9AEC8_LEIMA

TriTrypDb:

LmjF.29.2660 , LMJLV39_290034800 , LMJSD75_290035100

Length:

953

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	11
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11

Expansion

Sequence features

E9AEC8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AEC8

Function

Biological processes
Term	Name	Level	Count
GO:0000018	regulation of DNA recombination	6	2
GO:0000723	telomere maintenance	5	2
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	2
GO:0006282	regulation of DNA repair	6	2
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006996	organelle organization	4	2
GO:0008152	metabolic process	1	12
GO:0009892	negative regulation of metabolic process	4	2
GO:0009987	cellular process	1	12
GO:0010569	regulation of double-strand break repair via homologous recombination	7	2
GO:0010605	negative regulation of macromolecule metabolic process	5	2
GO:0016043	cellular component organization	3	2
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	2
GO:0019222	regulation of metabolic process	3	2
GO:0031323	regulation of cellular metabolic process	4	2
GO:0031324	negative regulation of cellular metabolic process	5	2
GO:0032200	telomere organization	6	2
GO:0032204	regulation of telomere maintenance	6	2
GO:0032392	DNA geometric change	7	2
GO:0032508	DNA duplex unwinding	8	2
GO:0033043	regulation of organelle organization	5	2
GO:0033044	regulation of chromosome organization	6	2
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	2
GO:0044087	regulation of cellular component biogenesis	4	2
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0045910	negative regulation of DNA recombination	7	2
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	2
GO:0046483	heterocycle metabolic process	3	12
GO:0048519	negative regulation of biological process	3	2
GO:0048523	negative regulation of cellular process	4	2
GO:0048583	regulation of response to stimulus	3	2
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0051052	regulation of DNA metabolic process	5	2
GO:0051053	negative regulation of DNA metabolic process	6	2
GO:0051128	regulation of cellular component organization	4	2
GO:0051129	negative regulation of cellular component organization	5	2
GO:0051171	regulation of nitrogen compound metabolic process	4	2
GO:0051172	negative regulation of nitrogen compound metabolic process	5	2
GO:0051276	chromosome organization	5	2
GO:0060255	regulation of macromolecule metabolic process	4	2
GO:0065007	biological regulation	1	2
GO:0071103	DNA conformation change	6	2
GO:0071704	organic substance metabolic process	2	12
GO:0071840	cellular component organization or biogenesis	2	2
GO:0080090	regulation of primary metabolic process	4	2
GO:0080134	regulation of response to stress	4	2
GO:0080135	regulation of cellular response to stress	4	2
GO:0090304	nucleic acid metabolic process	4	2
GO:0090657	telomeric loop disassembly	6	2
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1904429	regulation of t-circle formation	5	2
GO:1904430	negative regulation of t-circle formation	6	2
GO:2000779	regulation of double-strand break repair	7	2
GO:2001020	obsolete regulation of response to DNA damage stimulus	5	2
GO:0006950	response to stress	2	3
GO:0006974	DNA damage response	4	3
GO:0033554	cellular response to stress	3	3
GO:0050896	response to stimulus	1	3
GO:0051716	cellular response to stimulus	2	3

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005515	protein binding	2	2
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0019899	enzyme binding	3	2
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0070182	DNA polymerase binding	4	2
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0016462	pyrophosphatase activity	5	1
GO:0016887	ATP hydrolysis activity	7	1
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	603	607	PF00656	0.513
CLV_MEL_PAP_1	498	504	PF00089	0.441
CLV_NRD_NRD_1	299	301	PF00675	0.275
CLV_NRD_NRD_1	700	702	PF00675	0.532
CLV_NRD_NRD_1	722	724	PF00675	0.494
CLV_NRD_NRD_1	775	777	PF00675	0.552
CLV_NRD_NRD_1	849	851	PF00675	0.725
CLV_PCSK_FUR_1	628	632	PF00082	0.252
CLV_PCSK_FUR_1	773	777	PF00082	0.645
CLV_PCSK_KEX2_1	106	108	PF00082	0.263
CLV_PCSK_KEX2_1	299	301	PF00082	0.275
CLV_PCSK_KEX2_1	630	632	PF00082	0.252
CLV_PCSK_KEX2_1	699	701	PF00082	0.538
CLV_PCSK_KEX2_1	722	724	PF00082	0.471
CLV_PCSK_KEX2_1	773	775	PF00082	0.566
CLV_PCSK_KEX2_1	849	851	PF00082	0.538
CLV_PCSK_PC1ET2_1	106	108	PF00082	0.247
CLV_PCSK_PC1ET2_1	630	632	PF00082	0.252
CLV_PCSK_SKI1_1	103	107	PF00082	0.235
CLV_PCSK_SKI1_1	129	133	PF00082	0.353
CLV_PCSK_SKI1_1	295	299	PF00082	0.346
CLV_PCSK_SKI1_1	342	346	PF00082	0.409
CLV_PCSK_SKI1_1	364	368	PF00082	0.466
CLV_PCSK_SKI1_1	374	378	PF00082	0.434
CLV_PCSK_SKI1_1	401	405	PF00082	0.373
CLV_PCSK_SKI1_1	557	561	PF00082	0.242
CLV_PCSK_SKI1_1	610	614	PF00082	0.338
CLV_PCSK_SKI1_1	647	651	PF00082	0.252
CLV_PCSK_SKI1_1	781	785	PF00082	0.632
CLV_PCSK_SKI1_1	881	885	PF00082	0.444
CLV_PCSK_SKI1_1	891	895	PF00082	0.470
CLV_PCSK_SKI1_1	913	917	PF00082	0.470
DEG_SPOP_SBC_1	242	246	PF00917	0.557
DEG_SPOP_SBC_1	805	809	PF00917	0.531
DOC_CYCLIN_RxL_1	217	225	PF00134	0.463
DOC_CYCLIN_RxL_1	412	423	PF00134	0.479
DOC_CYCLIN_RxL_1	46	57	PF00134	0.369
DOC_CYCLIN_RxL_1	888	897	PF00134	0.495
DOC_CYCLIN_yCln2_LP_2	168	171	PF00134	0.474
DOC_MAPK_gen_1	299	305	PF00069	0.494
DOC_MAPK_gen_1	595	604	PF00069	0.465
DOC_MAPK_gen_1	672	681	PF00069	0.513
DOC_MAPK_MEF2A_6	586	593	PF00069	0.476
DOC_MAPK_NFAT4_5	586	594	PF00069	0.477
DOC_PP1_RVXF_1	413	420	PF00149	0.472
DOC_PP2B_LxvP_1	168	171	PF13499	0.474
DOC_PP2B_LxvP_1	908	911	PF13499	0.496
DOC_PP4_FxxP_1	560	563	PF00568	0.452
DOC_USP7_MATH_1	142	146	PF00917	0.471
DOC_USP7_MATH_1	164	168	PF00917	0.530
DOC_USP7_MATH_1	375	379	PF00917	0.509
DOC_USP7_MATH_1	434	438	PF00917	0.475
DOC_USP7_MATH_1	563	567	PF00917	0.533
DOC_USP7_MATH_1	783	787	PF00917	0.613
DOC_USP7_MATH_1	791	795	PF00917	0.631
DOC_USP7_MATH_1	805	809	PF00917	0.724
DOC_USP7_MATH_1	911	915	PF00917	0.511
DOC_USP7_UBL2_3	79	83	PF12436	0.625
DOC_WW_Pin1_4	249	254	PF00397	0.504
DOC_WW_Pin1_4	313	318	PF00397	0.648
DOC_WW_Pin1_4	40	45	PF00397	0.372
DOC_WW_Pin1_4	430	435	PF00397	0.431
DOC_WW_Pin1_4	443	448	PF00397	0.344
DOC_WW_Pin1_4	512	517	PF00397	0.463
DOC_WW_Pin1_4	580	585	PF00397	0.538
DOC_WW_Pin1_4	794	799	PF00397	0.648
DOC_WW_Pin1_4	894	899	PF00397	0.504
LIG_14-3-3_CanoR_1	107	111	PF00244	0.538
LIG_14-3-3_CanoR_1	113	117	PF00244	0.538
LIG_14-3-3_CanoR_1	133	143	PF00244	0.432
LIG_14-3-3_CanoR_1	271	279	PF00244	0.619
LIG_14-3-3_CanoR_1	374	380	PF00244	0.522
LIG_14-3-3_CanoR_1	495	499	PF00244	0.437
LIG_14-3-3_CanoR_1	595	604	PF00244	0.448
LIG_14-3-3_CanoR_1	703	712	PF00244	0.460
LIG_14-3-3_CanoR_1	723	733	PF00244	0.346
LIG_14-3-3_CanoR_1	849	857	PF00244	0.561
LIG_Actin_WH2_2	573	588	PF00022	0.557
LIG_Actin_WH2_2	880	897	PF00022	0.523
LIG_APCC_ABBA_1	303	308	PF00400	0.506
LIG_APCC_ABBAyCdc20_2	701	707	PF00400	0.394
LIG_BRCT_BRCA1_1	12	16	PF00533	0.371
LIG_BRCT_BRCA1_1	328	332	PF00533	0.469
LIG_BRCT_BRCA1_1	398	402	PF00533	0.467
LIG_BRCT_BRCA1_1	860	864	PF00533	0.437
LIG_EH1_1	175	183	PF00400	0.452
LIG_FHA_1	113	119	PF00498	0.476
LIG_FHA_1	255	261	PF00498	0.416
LIG_FHA_1	339	345	PF00498	0.394
LIG_FHA_1	398	404	PF00498	0.468
LIG_FHA_1	48	54	PF00498	0.355
LIG_FHA_1	544	550	PF00498	0.493
LIG_FHA_1	580	586	PF00498	0.535
LIG_FHA_1	727	733	PF00498	0.673
LIG_FHA_1	829	835	PF00498	0.752
LIG_FHA_1	843	849	PF00498	0.548
LIG_FHA_1	97	103	PF00498	0.505
LIG_FHA_2	318	324	PF00498	0.533
LIG_FHA_2	648	654	PF00498	0.452
LIG_FHA_2	821	827	PF00498	0.700
LIG_FHA_2	858	864	PF00498	0.460
LIG_LIR_Gen_1	329	340	PF02991	0.469
LIG_LIR_Gen_1	525	533	PF02991	0.452
LIG_LIR_Gen_1	623	634	PF02991	0.453
LIG_LIR_Gen_1	702	713	PF02991	0.438
LIG_LIR_Gen_1	861	872	PF02991	0.405
LIG_LIR_Gen_1	875	885	PF02991	0.380
LIG_LIR_Gen_1	926	936	PF02991	0.502
LIG_LIR_Nem_3	13	19	PF02991	0.390
LIG_LIR_Nem_3	188	193	PF02991	0.481
LIG_LIR_Nem_3	329	335	PF02991	0.447
LIG_LIR_Nem_3	416	422	PF02991	0.334
LIG_LIR_Nem_3	548	553	PF02991	0.460
LIG_LIR_Nem_3	623	629	PF02991	0.453
LIG_LIR_Nem_3	675	680	PF02991	0.444
LIG_LIR_Nem_3	684	690	PF02991	0.439
LIG_LIR_Nem_3	702	708	PF02991	0.254
LIG_LIR_Nem_3	861	867	PF02991	0.426
LIG_LIR_Nem_3	875	880	PF02991	0.344
LIG_LIR_Nem_3	926	931	PF02991	0.439
LIG_LIR_Nem_3	937	942	PF02991	0.353
LIG_MYND_1	855	859	PF01753	0.636
LIG_NRBOX	293	299	PF00104	0.444
LIG_PCNA_PIPBox_1	379	388	PF02747	0.496
LIG_PCNA_PIPBox_1	529	538	PF02747	0.557
LIG_PCNA_yPIPBox_3	661	671	PF02747	0.452
LIG_Pex14_2	190	194	PF04695	0.513
LIG_REV1ctd_RIR_1	716	727	PF16727	0.563
LIG_SH2_CRK	210	214	PF00017	0.463
LIG_SH2_CRK	677	681	PF00017	0.463
LIG_SH2_CRK	712	716	PF00017	0.350
LIG_SH2_GRB2like	619	622	PF00017	0.509
LIG_SH2_NCK_1	712	716	PF00017	0.350
LIG_SH2_NCK_1	757	761	PF00017	0.663
LIG_SH2_PTP2	734	737	PF00017	0.638
LIG_SH2_SRC	306	309	PF00017	0.559
LIG_SH2_SRC	619	622	PF00017	0.538
LIG_SH2_SRC	757	760	PF00017	0.668
LIG_SH2_STAP1	110	114	PF00017	0.513
LIG_SH2_STAP1	712	716	PF00017	0.350
LIG_SH2_STAP1	943	947	PF00017	0.458
LIG_SH2_STAT3	19	22	PF00017	0.394
LIG_SH2_STAT5	193	196	PF00017	0.494
LIG_SH2_STAT5	212	215	PF00017	0.342
LIG_SH2_STAT5	633	636	PF00017	0.444
LIG_SH2_STAT5	734	737	PF00017	0.638
LIG_SH2_STAT5	90	93	PF00017	0.452
LIG_SH3_3	203	209	PF00018	0.452
LIG_SH3_3	210	216	PF00018	0.452
LIG_SH3_3	428	434	PF00018	0.504
LIG_SH3_3	518	524	PF00018	0.452
LIG_SH3_3	636	642	PF00018	0.477
LIG_SH3_3	795	801	PF00018	0.644
LIG_SH3_3	9	15	PF00018	0.402
LIG_SUMO_SIM_anti_2	204	209	PF11976	0.530
LIG_SUMO_SIM_anti_2	829	834	PF11976	0.544
LIG_SUMO_SIM_par_1	229	235	PF11976	0.453
LIG_SUMO_SIM_par_1	252	258	PF11976	0.421
LIG_SUMO_SIM_par_1	678	685	PF11976	0.513
LIG_SUMO_SIM_par_1	829	836	PF11976	0.508
LIG_TRAF2_1	284	287	PF00917	0.496
LIG_TRFH_1	212	216	PF08558	0.538
LIG_TYR_ITIM	732	737	PF00017	0.644
LIG_UBA3_1	331	337	PF00899	0.356
LIG_UBA3_1	552	557	PF00899	0.493
LIG_UBA3_1	625	630	PF00899	0.452
MOD_CDC14_SPxK_1	583	586	PF00782	0.538
MOD_CDK_SPxK_1	580	586	PF00069	0.538
MOD_CK1_1	241	247	PF00069	0.508
MOD_CK1_1	493	499	PF00069	0.543
MOD_CK1_1	525	531	PF00069	0.474
MOD_CK1_1	62	68	PF00069	0.507
MOD_CK1_1	749	755	PF00069	0.677
MOD_CK1_1	794	800	PF00069	0.623
MOD_CK1_1	8	14	PF00069	0.492
MOD_CK1_1	807	813	PF00069	0.653
MOD_CK1_1	820	826	PF00069	0.637
MOD_CK2_1	249	255	PF00069	0.477
MOD_CK2_1	528	534	PF00069	0.544
MOD_CK2_1	690	696	PF00069	0.543
MOD_CK2_1	820	826	PF00069	0.701
MOD_CK2_1	857	863	PF00069	0.429
MOD_GlcNHglycan	144	147	PF01048	0.328
MOD_GlcNHglycan	156	159	PF01048	0.310
MOD_GlcNHglycan	160	163	PF01048	0.298
MOD_GlcNHglycan	187	190	PF01048	0.338
MOD_GlcNHglycan	245	248	PF01048	0.278
MOD_GlcNHglycan	353	356	PF01048	0.573
MOD_GlcNHglycan	441	444	PF01048	0.363
MOD_GlcNHglycan	483	486	PF01048	0.428
MOD_GlcNHglycan	539	542	PF01048	0.301
MOD_GlcNHglycan	6	10	PF01048	0.499
MOD_GlcNHglycan	61	64	PF01048	0.327
MOD_GlcNHglycan	749	752	PF01048	0.525
MOD_GlcNHglycan	785	788	PF01048	0.654
MOD_GlcNHglycan	793	796	PF01048	0.581
MOD_GSK3_1	129	136	PF00069	0.525
MOD_GSK3_1	154	161	PF00069	0.530
MOD_GSK3_1	238	245	PF00069	0.475
MOD_GSK3_1	311	318	PF00069	0.598
MOD_GSK3_1	346	353	PF00069	0.572
MOD_GSK3_1	40	47	PF00069	0.392
MOD_GSK3_1	430	437	PF00069	0.380
MOD_GSK3_1	439	446	PF00069	0.346
MOD_GSK3_1	490	497	PF00069	0.527
MOD_GSK3_1	512	519	PF00069	0.516
MOD_GSK3_1	699	706	PF00069	0.520
MOD_GSK3_1	800	807	PF00069	0.646
MOD_LATS_1	645	651	PF00433	0.534
MOD_N-GLC_1	563	568	PF02516	0.324
MOD_N-GLC_1	620	625	PF02516	0.263
MOD_N-GLC_1	739	744	PF02516	0.694
MOD_N-GLC_2	664	666	PF02516	0.263
MOD_NEK2_1	105	110	PF00069	0.474
MOD_NEK2_1	243	248	PF00069	0.501
MOD_NEK2_1	25	30	PF00069	0.454
MOD_NEK2_1	254	259	PF00069	0.359
MOD_NEK2_1	358	363	PF00069	0.517
MOD_NEK2_1	397	402	PF00069	0.431
MOD_NEK2_1	422	427	PF00069	0.358
MOD_NEK2_1	439	444	PF00069	0.347
MOD_NEK2_1	504	509	PF00069	0.409
MOD_NEK2_1	53	58	PF00069	0.359
MOD_NEK2_1	61	66	PF00069	0.391
MOD_NEK2_1	690	695	PF00069	0.557
MOD_NEK2_1	804	809	PF00069	0.724
MOD_NEK2_1	842	847	PF00069	0.702
MOD_NEK2_1	893	898	PF00069	0.574
MOD_NEK2_1	946	951	PF00069	0.527
MOD_NEK2_2	490	495	PF00069	0.480
MOD_NEK2_2	911	916	PF00069	0.511
MOD_NEK2_2	923	928	PF00069	0.339
MOD_PIKK_1	134	140	PF00454	0.533
MOD_PIKK_1	317	323	PF00454	0.597
MOD_PIKK_1	62	68	PF00454	0.560
MOD_PIKK_1	817	823	PF00454	0.698
MOD_PIKK_1	96	102	PF00454	0.469
MOD_PKA_1	106	112	PF00069	0.538
MOD_PKA_1	699	705	PF00069	0.412
MOD_PKA_2	106	112	PF00069	0.541
MOD_PKA_2	270	276	PF00069	0.570
MOD_PKA_2	494	500	PF00069	0.428
MOD_PKA_2	699	705	PF00069	0.442
MOD_PKA_2	724	730	PF00069	0.647
MOD_PKA_2	836	842	PF00069	0.694
MOD_PKA_2	848	854	PF00069	0.758
MOD_PKB_1	701	709	PF00069	0.523
MOD_Plk_1	129	135	PF00069	0.557
MOD_Plk_1	397	403	PF00069	0.437
MOD_Plk_1	422	428	PF00069	0.434
MOD_Plk_1	828	834	PF00069	0.656
MOD_Plk_4	164	170	PF00069	0.530
MOD_Plk_4	238	244	PF00069	0.495
MOD_Plk_4	326	332	PF00069	0.383
MOD_Plk_4	364	370	PF00069	0.498
MOD_Plk_4	434	440	PF00069	0.406
MOD_Plk_4	516	522	PF00069	0.522
MOD_Plk_4	528	534	PF00069	0.497
MOD_Plk_4	545	551	PF00069	0.448
MOD_Plk_4	568	574	PF00069	0.487
MOD_Plk_4	828	834	PF00069	0.714
MOD_Plk_4	923	929	PF00069	0.542
MOD_ProDKin_1	249	255	PF00069	0.502
MOD_ProDKin_1	313	319	PF00069	0.648
MOD_ProDKin_1	40	46	PF00069	0.383
MOD_ProDKin_1	430	436	PF00069	0.429
MOD_ProDKin_1	443	449	PF00069	0.345
MOD_ProDKin_1	512	518	PF00069	0.463
MOD_ProDKin_1	580	586	PF00069	0.538
MOD_ProDKin_1	794	800	PF00069	0.650
MOD_ProDKin_1	894	900	PF00069	0.499
MOD_SUMO_rev_2	540	549	PF00179	0.538
MOD_SUMO_rev_2	554	559	PF00179	0.479
MOD_SUMO_rev_2	778	786	PF00179	0.645
TRG_DiLeu_BaEn_2	862	868	PF01217	0.417
TRG_DiLeu_BaEn_4	286	292	PF01217	0.430
TRG_DiLeu_BaEn_4	937	943	PF01217	0.544
TRG_DiLeu_BaLyEn_6	889	894	PF01217	0.561
TRG_ENDOCYTIC_2	210	213	PF00928	0.451
TRG_ENDOCYTIC_2	526	529	PF00928	0.452
TRG_ENDOCYTIC_2	677	680	PF00928	0.457
TRG_ENDOCYTIC_2	712	715	PF00928	0.354
TRG_ENDOCYTIC_2	734	737	PF00928	0.638
TRG_ENDOCYTIC_2	877	880	PF00928	0.371
TRG_ENDOCYTIC_2	943	946	PF00928	0.414
TRG_ER_diArg_1	298	300	PF00400	0.275
TRG_ER_diArg_1	698	701	PF00400	0.594
TRG_ER_diArg_1	722	725	PF00400	0.489
TRG_ER_diArg_1	773	776	PF00400	0.563
TRG_ER_diArg_1	848	850	PF00400	0.543
TRG_NES_CRM1_1	384	398	PF08389	0.450
TRG_Pf-PMV_PEXEL_1	933	937	PF00026	0.513
TRG_Pf-PMV_PEXEL_1	940	945	PF00026	0.510

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6K3	Leptomonas seymouri	71%	99%
A0A0N1PBH5	Leptomonas seymouri	24%	100%
A0A0P0V4R0	Oryza sativa subsp. japonica	35%	94%
A0A0S4KH73	Bodo saltans	38%	92%
A0A1X0P9Z9	Trypanosomatidae	47%	98%
A0A3R7MDU1	Trypanosoma rangeli	51%	98%
A0A3S7X2X3	Leishmania donovani	93%	100%
A1D8E4	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	27%	100%
A2QY22	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	26%	100%
A3LN13	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	24%	100%
A4HDT9	Leishmania braziliensis	24%	100%
A4HHR4	Leishmania braziliensis	86%	100%
A4I4X4	Leishmania infantum	94%	100%
A4K436	Bos taurus	35%	78%
A5DNW6	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	25%	100%
A5DUW8	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	27%	100%
A6ZWN8	Saccharomyces cerevisiae (strain YJM789)	24%	100%
A8MPP1	Homo sapiens	26%	100%
A8WS58	Caenorhabditis briggsae	31%	96%
B0W9F4	Culex quinquefasciatus	30%	97%
B3MSG8	Drosophila ananassae	33%	96%
B3NSW1	Drosophila erecta	33%	97%
B4GU19	Drosophila persimilis	32%	94%
B4I0K4	Drosophila sechellia	31%	99%
B4JNS2	Drosophila grimshawi	33%	97%
B4L1Z2	Drosophila mojavensis	32%	94%
B4M891	Drosophila virilis	32%	95%
B4NDG5	Drosophila willistoni	33%	95%
B4PZB4	Drosophila yakuba	34%	97%
C9ZKX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	99%
E9ALF8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
E9AX74	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
F1R345	Danio rerio	28%	100%
F4HQE2	Arabidopsis thaliana	34%	92%
O14147	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
P06839	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	100%
P0C928	Danio rerio	33%	81%
P22516	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P26659	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
Q0VGM9	Mus musculus	34%	79%
Q16X92	Aedes aegypti	30%	94%
Q1E5T3	Coccidioides immitis (strain RS)	27%	100%
Q21489	Caenorhabditis elegans	25%	100%
Q29FS3	Drosophila pseudoobscura pseudoobscura	32%	94%
Q2U587	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	26%	100%
Q3YK19	Gallus gallus	29%	76%
Q4QAA2	Leishmania major	24%	100%
Q4WWE9	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	27%	100%
Q55G81	Dictyostelium discoideum	25%	100%
Q5AD67	Candida albicans (strain SC5314 / ATCC MYA-2876)	25%	100%
Q5RE34	Pongo abelii	34%	73%
Q5RJZ1	Rattus norvegicus	33%	75%
Q5SXJ3	Mus musculus	29%	81%
Q6AXC6	Mus musculus	27%	100%
Q6BZD9	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	25%	100%
Q6CAX3	Yarrowia lipolytica (strain CLIB 122 / E 150)	26%	100%
Q6CIF0	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	25%	100%
Q6FKT4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	25%	100%
Q6H1L8	Mus spretus	34%	79%
Q750G3	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	25%	100%
Q7QEI1	Anopheles gambiae	33%	96%
Q92771	Homo sapiens	27%	100%
Q93575	Caenorhabditis elegans	31%	96%
Q96FC9	Homo sapiens	27%	98%
Q9BX63	Homo sapiens	28%	76%
Q9NZ71	Homo sapiens	34%	78%
Q9W484	Drosophila melanogaster	33%	97%
V5BAP9	Trypanosoma cruzi	28%	100%
V5BX91	Trypanosoma cruzi	49%	100%