Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AEC3_LEIMA

TriTrypDb:

LmjF.29.2610 , LMJLV39_290034200 , LMJSD75_290034600

Length:

718

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AEC3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AEC3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	376	380	PF00656	0.584
CLV_NRD_NRD_1	377	379	PF00675	0.656
CLV_NRD_NRD_1	400	402	PF00675	0.618
CLV_NRD_NRD_1	656	658	PF00675	0.524
CLV_NRD_NRD_1	681	683	PF00675	0.521
CLV_PCSK_KEX2_1	28	30	PF00082	0.570
CLV_PCSK_KEX2_1	377	379	PF00082	0.656
CLV_PCSK_KEX2_1	400	402	PF00082	0.671
CLV_PCSK_KEX2_1	608	610	PF00082	0.421
CLV_PCSK_KEX2_1	656	658	PF00082	0.524

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I841	Leptomonas seymouri	43%	97%
A0A3S7X2Z5	Leishmania donovani	90%	100%
A4HHQ9	Leishmania braziliensis	74%	100%
A4I4T7	Leishmania infantum	90%	100%
E9ALG3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%

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