Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cdc2-related kinase 10, putative

Species:

Leishmania major

UniProt:

E9AE77_LEIMA

TriTrypDb:

LmjF.29.2150 , LMJLV39_290029500 , LMJSD75_290029600

Length:

428

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 16
NetGPI	no	yes: 0, no: 16

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	3
GO:0016592	mediator complex	3	2
GO:0032991	protein-containing complex	1	2
GO:0043226	organelle	2	3
GO:0043227	membrane-bounded organelle	3	3
GO:0043229	intracellular organelle	3	3
GO:0043231	intracellular membrane-bounded organelle	4	3
GO:0110165	cellular anatomical entity	1	3
GO:0140513	nuclear protein-containing complex	2	2
GO:0005737	cytoplasm	2	1
GO:0005739	mitochondrion	5	1

Expansion

Sequence features

E9AE77

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AE77

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	17
GO:0006793	phosphorus metabolic process	3	17
GO:0006796	phosphate-containing compound metabolic process	4	17
GO:0006807	nitrogen compound metabolic process	2	17
GO:0008152	metabolic process	1	17
GO:0009987	cellular process	1	17
GO:0016310	phosphorylation	5	17
GO:0019538	protein metabolic process	3	17
GO:0036211	protein modification process	4	17
GO:0043170	macromolecule metabolic process	3	17
GO:0043412	macromolecule modification	4	17
GO:0044237	cellular metabolic process	2	17
GO:0044238	primary metabolic process	2	17
GO:0071704	organic substance metabolic process	2	17
GO:1901564	organonitrogen compound metabolic process	3	17
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	4	1
GO:0006355	regulation of DNA-templated transcription	6	1
GO:0009889	regulation of biosynthetic process	4	1
GO:0010468	regulation of gene expression	5	1
GO:0010556	regulation of macromolecule biosynthetic process	5	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0022402	cell cycle process	2	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031326	regulation of cellular biosynthetic process	5	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051252	regulation of RNA metabolic process	5	1
GO:0051301	cell division	2	6
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0080090	regulation of primary metabolic process	4	1
GO:1903047	mitotic cell cycle process	3	1
GO:1903506	regulation of nucleic acid-templated transcription	7	1
GO:2001141	regulation of RNA biosynthetic process	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	17
GO:0003824	catalytic activity	1	17
GO:0004672	protein kinase activity	3	17
GO:0004674	protein serine/threonine kinase activity	4	8
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5	3
GO:0005488	binding	1	17
GO:0005524	ATP binding	5	17
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	5	2
GO:0016301	kinase activity	4	17
GO:0016740	transferase activity	2	17
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	17
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	17
GO:0017076	purine nucleotide binding	4	17
GO:0030554	adenyl nucleotide binding	5	17
GO:0032553	ribonucleotide binding	3	17
GO:0032555	purine ribonucleotide binding	4	17
GO:0032559	adenyl ribonucleotide binding	5	17
GO:0035639	purine ribonucleoside triphosphate binding	4	17
GO:0036094	small molecule binding	2	17
GO:0043167	ion binding	2	17
GO:0043168	anion binding	3	17
GO:0097159	organic cyclic compound binding	2	17
GO:0097367	carbohydrate derivative binding	2	17
GO:0097472	cyclin-dependent protein kinase activity	4	3
GO:0140096	catalytic activity, acting on a protein	2	17
GO:1901265	nucleoside phosphate binding	3	17
GO:1901363	heterocyclic compound binding	2	17

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	406	410	PF00656	0.352
CLV_NRD_NRD_1	112	114	PF00675	0.504
CLV_NRD_NRD_1	176	178	PF00675	0.321
CLV_NRD_NRD_1	98	100	PF00675	0.691
CLV_PCSK_KEX2_1	111	113	PF00082	0.538
CLV_PCSK_KEX2_1	176	178	PF00082	0.323
CLV_PCSK_KEX2_1	208	210	PF00082	0.410
CLV_PCSK_KEX2_1	4	6	PF00082	0.482
CLV_PCSK_PC1ET2_1	208	210	PF00082	0.410
CLV_PCSK_PC1ET2_1	4	6	PF00082	0.478
CLV_PCSK_SKI1_1	100	104	PF00082	0.412
CLV_PCSK_SKI1_1	153	157	PF00082	0.393
CLV_PCSK_SKI1_1	197	201	PF00082	0.325
CLV_PCSK_SKI1_1	314	318	PF00082	0.282
CLV_PCSK_SKI1_1	373	377	PF00082	0.410
CLV_PCSK_SKI1_1	379	383	PF00082	0.376
CLV_PCSK_SKI1_1	41	45	PF00082	0.653
CLV_PCSK_SKI1_1	414	418	PF00082	0.351
CLV_PCSK_SKI1_1	48	52	PF00082	0.741
DEG_APCC_DBOX_1	117	125	PF00400	0.410
DEG_APCC_DBOX_1	131	139	PF00400	0.410
DEG_APCC_DBOX_1	378	386	PF00400	0.310
DEG_SPOP_SBC_1	90	94	PF00917	0.687
DOC_CYCLIN_RxL_1	392	402	PF00134	0.327
DOC_MAPK_gen_1	116	124	PF00069	0.310
DOC_MAPK_gen_1	173	182	PF00069	0.410
DOC_MAPK_gen_1	197	206	PF00069	0.323
DOC_MAPK_gen_1	377	384	PF00069	0.410
DOC_MAPK_HePTP_8	174	186	PF00069	0.410
DOC_MAPK_JIP1_4	200	206	PF00069	0.380
DOC_MAPK_MEF2A_6	176	184	PF00069	0.371
DOC_MIT_MIM_1	391	399	PF04212	0.410
DOC_USP7_MATH_1	219	223	PF00917	0.395
DOC_USP7_MATH_1	298	302	PF00917	0.320
DOC_USP7_MATH_1	31	35	PF00917	0.708
DOC_USP7_MATH_1	323	327	PF00917	0.317
DOC_USP7_MATH_1	56	60	PF00917	0.733
DOC_USP7_MATH_1	90	94	PF00917	0.562
DOC_WW_Pin1_4	268	273	PF00397	0.282
DOC_WW_Pin1_4	321	326	PF00397	0.446
LIG_14-3-3_CanoR_1	160	166	PF00244	0.388
LIG_14-3-3_CanoR_1	176	181	PF00244	0.234
LIG_14-3-3_CanoR_1	404	408	PF00244	0.336
LIG_Actin_WH2_2	8	23	PF00022	0.485
LIG_BRCT_BRCA1_1	162	166	PF00533	0.310
LIG_BRCT_BRCA1_1	214	218	PF00533	0.278
LIG_BRCT_BRCA1_1	300	304	PF00533	0.320
LIG_Clathr_ClatBox_1	396	400	PF01394	0.360
LIG_CtBP_PxDLS_1	389	395	PF00389	0.326
LIG_deltaCOP1_diTrp_1	147	151	PF00928	0.410
LIG_FHA_1	208	214	PF00498	0.397
LIG_FHA_1	239	245	PF00498	0.412
LIG_FHA_2	17	23	PF00498	0.382
LIG_FHA_2	354	360	PF00498	0.407
LIG_FHA_2	404	410	PF00498	0.355
LIG_FHA_2	7	13	PF00498	0.538
LIG_LIR_Apic_2	266	272	PF02991	0.281
LIG_LIR_Gen_1	147	157	PF02991	0.429
LIG_LIR_Gen_1	338	347	PF02991	0.414
LIG_LIR_Gen_1	417	426	PF02991	0.513
LIG_LIR_Nem_3	163	169	PF02991	0.471
LIG_LIR_Nem_3	215	220	PF02991	0.329
LIG_LIR_Nem_3	338	343	PF02991	0.316
LIG_LIR_Nem_3	417	423	PF02991	0.498
LIG_MLH1_MIPbox_1	214	218	PF16413	0.193
LIG_PTB_Apo_2	275	282	PF02174	0.282
LIG_PTB_Phospho_1	275	281	PF10480	0.282
LIG_RPA_C_Fungi	107	119	PF08784	0.404
LIG_RPA_C_Fungi	71	83	PF08784	0.591
LIG_SH2_NCK_1	420	424	PF00017	0.503
LIG_SH2_SRC	340	343	PF00017	0.310
LIG_SH2_SRC	347	350	PF00017	0.250
LIG_SH2_SRC	420	423	PF00017	0.502
LIG_SH2_STAP1	240	244	PF00017	0.310
LIG_SH2_STAP1	281	285	PF00017	0.305
LIG_SH2_STAP1	340	344	PF00017	0.341
LIG_SH2_STAP1	420	424	PF00017	0.503
LIG_SH2_STAT5	137	140	PF00017	0.364
LIG_SH2_STAT5	142	145	PF00017	0.334
LIG_SH2_STAT5	240	243	PF00017	0.292
LIG_SH2_STAT5	260	263	PF00017	0.407
LIG_SH2_STAT5	281	284	PF00017	0.316
LIG_SH2_STAT5	336	339	PF00017	0.410
LIG_SH2_STAT5	77	80	PF00017	0.592
LIG_SH3_3	47	53	PF00018	0.714
LIG_SUMO_SIM_anti_2	179	184	PF11976	0.278
LIG_SUMO_SIM_anti_2	22	28	PF11976	0.520
LIG_SUMO_SIM_par_1	395	400	PF11976	0.310
LIG_TRAF2_1	356	359	PF00917	0.310
LIG_WRC_WIRS_1	214	219	PF05994	0.193
MOD_CK1_1	158	164	PF00069	0.278
MOD_CK1_1	222	228	PF00069	0.364
MOD_CK1_1	30	36	PF00069	0.642
MOD_CK1_1	66	72	PF00069	0.513
MOD_CK1_1	92	98	PF00069	0.510
MOD_CK2_1	16	22	PF00069	0.447
MOD_CK2_1	247	253	PF00069	0.307
MOD_CK2_1	353	359	PF00069	0.392
MOD_CK2_1	6	12	PF00069	0.575
MOD_GlcNHglycan	106	109	PF01048	0.384
MOD_GlcNHglycan	162	165	PF01048	0.414
MOD_GlcNHglycan	221	224	PF01048	0.402
MOD_GlcNHglycan	27	32	PF01048	0.680
MOD_GlcNHglycan	283	286	PF01048	0.312
MOD_GlcNHglycan	298	301	PF01048	0.222
MOD_GlcNHglycan	79	82	PF01048	0.568
MOD_GlcNHglycan	94	97	PF01048	0.458
MOD_GSK3_1	155	162	PF00069	0.278
MOD_GSK3_1	219	226	PF00069	0.354
MOD_GSK3_1	27	34	PF00069	0.515
MOD_GSK3_1	349	356	PF00069	0.369
MOD_GSK3_1	52	59	PF00069	0.565
MOD_GSK3_1	63	70	PF00069	0.520
MOD_N-GLC_1	223	228	PF02516	0.390
MOD_N-GLC_1	279	284	PF02516	0.332
MOD_N-GLC_1	353	358	PF02516	0.466
MOD_N-GLC_1	7	12	PF02516	0.677
MOD_NEK2_1	155	160	PF00069	0.423
MOD_NEK2_1	188	193	PF00069	0.401
MOD_NEK2_1	247	252	PF00069	0.327
MOD_NEK2_1	276	281	PF00069	0.356
MOD_NEK2_1	6	11	PF00069	0.495
MOD_PK_1	176	182	PF00069	0.278
MOD_PKA_1	112	118	PF00069	0.384
MOD_PKA_1	176	182	PF00069	0.415
MOD_PKA_2	112	118	PF00069	0.552
MOD_PKA_2	159	165	PF00069	0.428
MOD_PKA_2	176	182	PF00069	0.290
MOD_PKA_2	366	372	PF00069	0.390
MOD_PKA_2	403	409	PF00069	0.339
MOD_PKA_2	51	57	PF00069	0.666
MOD_Plk_1	279	285	PF00069	0.365
MOD_Plk_1	6	12	PF00069	0.625
MOD_Plk_2-3	7	13	PF00069	0.616
MOD_Plk_4	213	219	PF00069	0.193
MOD_Plk_4	263	269	PF00069	0.339
MOD_Plk_4	298	304	PF00069	0.351
MOD_Plk_4	323	329	PF00069	0.337
MOD_Plk_4	403	409	PF00069	0.410
MOD_Plk_4	67	73	PF00069	0.694
MOD_ProDKin_1	268	274	PF00069	0.282
MOD_ProDKin_1	321	327	PF00069	0.446
TRG_DiLeu_BaLyEn_6	392	397	PF01217	0.276
TRG_ENDOCYTIC_2	137	140	PF00928	0.381
TRG_ENDOCYTIC_2	340	343	PF00928	0.327
TRG_ENDOCYTIC_2	420	423	PF00928	0.530
TRG_ER_diArg_1	111	113	PF00400	0.541
TRG_ER_diArg_1	129	132	PF00400	0.441
TRG_ER_diArg_1	175	177	PF00400	0.356
TRG_ER_diArg_1	329	332	PF00400	0.310
TRG_Pf-PMV_PEXEL_1	197	202	PF00026	0.323
TRG_Pf-PMV_PEXEL_1	395	400	PF00026	0.285

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P661	Leptomonas seymouri	60%	68%
A0A0N0P759	Leptomonas seymouri	28%	90%
A0A0N0P7D2	Leptomonas seymouri	30%	100%
A0A0N1I0C1	Leptomonas seymouri	29%	96%
A0A0N1I3G0	Leptomonas seymouri	26%	100%
A0A0N1IHY4	Leptomonas seymouri	25%	100%
A0A0N1II59	Leptomonas seymouri	29%	100%
A0A0N1IL28	Leptomonas seymouri	24%	100%
A0A0N1PDG8	Leptomonas seymouri	25%	100%
A0A0S4ILC2	Bodo saltans	25%	100%
A0A0S4IN21	Bodo saltans	25%	92%
A0A0S4IV16	Bodo saltans	27%	100%
A0A0S4IVQ6	Bodo saltans	26%	91%
A0A0S4IXW3	Bodo saltans	22%	99%
A0A0S4IYA6	Bodo saltans	25%	100%
A0A0S4JCK3	Bodo saltans	25%	100%
A0A0S4JCQ9	Bodo saltans	27%	100%
A0A0S4JMF5	Bodo saltans	35%	100%
A0A1X0NM44	Trypanosomatidae	28%	100%
A0A1X0NME1	Trypanosomatidae	27%	77%
A0A1X0P018	Trypanosomatidae	38%	77%
A0A1X0P020	Trypanosomatidae	27%	100%
A0A1X0P2I7	Trypanosomatidae	26%	100%
A0A1X0P4Z7	Trypanosomatidae	23%	77%
A0A1X0P6E7	Trypanosomatidae	25%	100%
A0A1X0P6U6	Trypanosomatidae	26%	100%
A0A1X0P859	Trypanosomatidae	26%	90%
A0A1X0P8A0	Trypanosomatidae	27%	100%
A0A1X0P8F7	Trypanosomatidae	25%	99%
A0A1X0P8R6	Trypanosomatidae	26%	100%
A0A3Q8IB74	Leishmania donovani	26%	100%
A0A3Q8IFK8	Leishmania donovani	24%	97%
A0A3Q8IIY5	Leishmania donovani	95%	100%
A0A3Q8INS5	Leishmania donovani	28%	100%
A0A3Q8IPR6	Leishmania donovani	29%	100%
A0A3Q8ITZ9	Leishmania donovani	26%	100%
A0A3Q8IVR8	Leishmania donovani	28%	94%
A0A3R7K5U6	Trypanosoma rangeli	25%	73%
A0A3R7K7W6	Trypanosoma rangeli	25%	100%
A0A3R7LCG7	Trypanosoma rangeli	30%	74%
A0A3R7M0A0	Trypanosoma rangeli	24%	100%
A0A3R7NAU1	Trypanosoma rangeli	27%	90%
A0A3R7NBN7	Trypanosoma rangeli	38%	98%
A0A3S5H4Z4	Leishmania donovani	24%	81%
A0A3S5H528	Leishmania donovani	26%	100%
A0A3S5H6Y0	Leishmania donovani	27%	100%
A0A3S5IRQ5	Trypanosoma rangeli	21%	100%
A0A3S7WP41	Leishmania donovani	27%	100%
A0A3S7WR45	Leishmania donovani	28%	100%
A0A3S7WWL1	Leishmania donovani	34%	100%
A0A3S7X2Z6	Leishmania donovani	27%	100%
A0A422NCX4	Trypanosoma rangeli	26%	100%
A0A422NQJ6	Trypanosoma rangeli	27%	100%
A0A422P2B2	Trypanosoma rangeli	27%	93%
A1CAF0	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	27%	100%
A1CPG7	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	24%	100%
A1D2C9	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	24%	100%
A1DES4	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	27%	100%
A1IVT7	Botryotinia fuckeliana (strain B05.10)	23%	100%
A2QN07	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	26%	100%
A2QRF6	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	23%	100%
A2XFC8	Oryza sativa subsp. indica	27%	100%
A2Y4B6	Oryza sativa subsp. indica	24%	100%
A3LN91	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	25%	100%
A3LUB9	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	25%	99%
A4H3J3	Leishmania braziliensis	26%	100%
A4H4A1	Leishmania braziliensis	29%	100%
A4H641	Leishmania braziliensis	29%	100%
A4H9X5	Leishmania braziliensis	25%	100%
A4HBW8	Leishmania braziliensis	34%	100%
A4HEL2	Leishmania braziliensis	29%	100%
A4HFI2	Leishmania braziliensis	30%	100%
A4HHL5	Leishmania braziliensis	83%	100%
A4HHY4	Leishmania braziliensis	27%	100%
A4HJT5	Leishmania braziliensis	25%	97%
A4HLJ9	Leishmania braziliensis	27%	100%
A4HNR5	Leishmania braziliensis	30%	100%
A4HRM6	Leishmania infantum	24%	81%
A4HRT2	Leishmania infantum	26%	100%
A4HSH7	Leishmania infantum	28%	100%
A4HUG1	Leishmania infantum	28%	100%
A4I1U3	Leishmania infantum	28%	100%
A4I4S4	Leishmania infantum	95%	74%
A4I564	Leishmania infantum	27%	100%
A4I7A1	Leishmania infantum	24%	97%
A4I910	Leishmania infantum	26%	100%
A4ICR2	Leishmania infantum	28%	94%
A4ICT0	Leishmania infantum	30%	100%
A8WIP6	Danio rerio	23%	100%
A8XA58	Caenorhabditis briggsae	28%	100%
A9S9Q8	Physcomitrium patens	28%	100%
B0XR80	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	24%	100%
B0Y462	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	27%	100%
B3WFY8	Caenorhabditis elegans	24%	88%
B6DTE5	Bodo saltans	26%	100%
C9ZJ15	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
C9ZKU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	73%
C9ZLG9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZR94	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
C9ZS83	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
C9ZVG3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
C9ZW07	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	92%
D0A0D6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A0U8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
D0A230	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D0A2P2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	97%
D0A4N2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	75%
D0A509	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
E9ACG8	Leishmania major	26%	100%
E9AD33	Leishmania major	29%	100%
E9AGS0	Leishmania infantum	26%	100%
E9AGX6	Leishmania infantum	34%	100%
E9AHC6	Leishmania infantum	28%	100%
E9AJQ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AKG1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ALK8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9AN59	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AQQ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	91%
E9ARW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9ASH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AV92	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AXY7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AYV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9B296	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	97%
E9B3X5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
M1T7M3	Wallemia ichthyophaga (strain EXF-994 / CBS 113033)	23%	100%
O08911	Mus musculus	27%	100%
O23236	Arabidopsis thaliana	27%	100%
O54833	Mus musculus	23%	100%
O59853	Zygosaccharomyces rouxii	27%	100%
O59854	Zygosaccharomyces rouxii	26%	100%
O93982	Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)	26%	99%
O96526	Leishmania major	30%	100%
P0C431	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	24%	100%
P0C661	Caenorhabditis briggsae	26%	70%
P0CP68	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	23%	100%
P0CP69	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	23%	100%
P0CS76	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	27%	92%
P0CS77	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	27%	92%
P19784	Homo sapiens	23%	100%
P20427	Bos taurus	23%	100%
P20793	Rattus norvegicus	25%	69%
P20794	Homo sapiens	25%	69%
P21708	Rattus norvegicus	28%	100%
P21869	Gallus gallus	23%	100%
P23111	Zea mays	29%	100%
P23572	Drosophila melanogaster	29%	100%
P24100	Arabidopsis thaliana	28%	100%
P27361	Homo sapiens	29%	100%
P29618	Oryza sativa subsp. japonica	29%	100%
P29619	Oryza sativa subsp. japonica	29%	100%
P29620	Oryza sativa subsp. japonica	24%	100%
P32485	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	98%
P42525	Dictyostelium discoideum	27%	81%
P43294	Arabidopsis thaliana	27%	97%
P46892	Rattus norvegicus	29%	98%
P49336	Homo sapiens	23%	92%
P50613	Homo sapiens	25%	100%
P51952	Rattus norvegicus	25%	100%
P53778	Homo sapiens	28%	100%
P54664	Trypanosoma congolense	35%	100%
P90866	Caenorhabditis elegans	25%	73%
P93101	Oxybasis rubra	31%	100%
Q03147	Mus musculus	25%	100%
Q04770	Entamoeba histolytica	27%	100%
Q04859	Mus musculus	25%	69%
Q05006	Medicago sativa	27%	100%
Q06060	Pisum sativum	27%	100%
Q07176	Medicago sativa	26%	100%
Q09892	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
Q0CIC7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	24%	100%
Q0J4I1	Oryza sativa subsp. japonica	28%	100%
Q0TWJ7	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	26%	97%
Q0U4L8	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	23%	100%
Q10N20	Oryza sativa subsp. japonica	27%	100%
Q15131	Homo sapiens	24%	100%
Q17IE8	Aedes aegypti	23%	85%
Q1DUU8	Coccidioides immitis (strain RS)	24%	100%
Q1EBK0	Coccidioides immitis (strain RS)	24%	92%
Q1L5Z8	Torulaspora delbrueckii	25%	100%
Q1RLU9	Danio rerio	28%	100%
Q26671	Theileria annulata	27%	100%
Q27032	Theileria parva	27%	100%
Q2H332	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	24%	100%
Q2QSL4	Oryza sativa subsp. japonica	29%	100%
Q2TBL8	Bos taurus	24%	100%
Q2U469	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	28%	100%
Q2V419	Arabidopsis thaliana	30%	100%
Q2WFL5	Cochliobolus miyabeanus	22%	100%
Q2WGK3	Trichoderma harzianum	24%	100%
Q336M2	Oryza sativa subsp. japonica	24%	90%
Q336X9	Oryza sativa subsp. japonica	28%	100%
Q38772	Antirrhinum majus	31%	100%
Q38774	Antirrhinum majus	28%	100%
Q38HL5	Aspergillus glaucus	24%	100%
Q39021	Arabidopsis thaliana	24%	100%
Q39022	Arabidopsis thaliana	25%	100%
Q39023	Arabidopsis thaliana	30%	100%
Q39024	Arabidopsis thaliana	28%	100%
Q39025	Arabidopsis thaliana	25%	100%
Q39026	Arabidopsis thaliana	27%	100%
Q39027	Arabidopsis thaliana	27%	100%
Q3UMM4	Mus musculus	25%	100%
Q40517	Nicotiana tabacum	26%	100%
Q40531	Nicotiana tabacum	30%	100%
Q40532	Nicotiana tabacum	29%	100%
Q40884	Petunia hybrida	25%	100%
Q41639	Vigna aconitifolia	29%	100%
Q4KM47	Rattus norvegicus	24%	100%
Q4PC06	Ustilago maydis (strain 521 / FGSC 9021)	22%	100%
Q4Q204	Leishmania major	27%	99%
Q4Q416	Leishmania major	24%	67%
Q4Q449	Leishmania major	26%	100%
Q4Q5W2	Leishmania major	23%	97%
Q4Q7S2	Leishmania major	27%	100%
Q4Q9I7	Leishmania major	28%	100%
Q4QC88	Leishmania major	34%	100%
Q4QDK3	Leishmania major	26%	100%
Q4QHG6	Leishmania major	28%	100%
Q4QJE7	Leishmania major	28%	100%
Q4W6D3	Cochliobolus heterostrophus	22%	100%
Q4WSF6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	24%	100%
Q4WUN7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	26%	100%
Q52PH6	Alternaria brassicicola	22%	100%
Q55FJ6	Dictyostelium discoideum	27%	84%
Q56R42	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	23%	100%
Q5AHK2	Candida albicans (strain SC5314 / ATCC MYA-2876)	24%	70%
Q5I6M2	Setosphaeria turcica	22%	100%
Q5J4W4	Oryza sativa subsp. japonica	27%	100%
Q5Z859	Oryza sativa subsp. japonica	26%	100%
Q63538	Rattus norvegicus	27%	100%
Q63844	Mus musculus	28%	100%
Q6BM25	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	25%	91%
Q6C4M9	Yarrowia lipolytica (strain CLIB 122 / E 150)	24%	100%
Q6CJA8	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	25%	96%
Q6FIU2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	96%
Q6FKC6	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	24%	75%
Q6P3N6	Xenopus tropicalis	23%	92%
Q6PWX2	Beauveria bassiana	24%	100%
Q6XKY3	Hypocrea atroviridis	24%	100%
Q6Z437	Oryza sativa subsp. japonica	26%	100%
Q6Z8C8	Oryza sativa subsp. japonica	26%	93%
Q702W0	Blastobotrys adeninivorans	24%	100%
Q750A9	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	25%	96%
Q75Q66	Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)	24%	100%
Q80YP0	Mus musculus	30%	100%
Q84M93	Arabidopsis thaliana	25%	88%
Q84TI6	Arabidopsis thaliana	26%	91%
Q84UI5	Oryza sativa subsp. japonica	26%	100%
Q875L0	Cryphonectria parasitica	24%	100%
Q8BWD8	Mus musculus	23%	85%
Q8GYQ5	Arabidopsis thaliana	27%	100%
Q8JH47	Danio rerio	24%	92%
Q8LF80	Arabidopsis thaliana	28%	100%
Q8LG64	Arabidopsis thaliana	26%	100%
Q8NJT7	Hortaea werneckii	23%	100%
Q8R3L8	Mus musculus	24%	92%
Q8SR90	Encephalitozoon cuniculi (strain GB-M1)	26%	100%
Q8TD08	Homo sapiens	28%	79%
Q8TGA9	Blumeria graminis	23%	100%
Q8WQ45	Leishmania donovani	30%	100%
Q92207	Candida albicans (strain SC5314 / ATCC MYA-2876)	25%	100%
Q95YH0	Dictyostelium discoideum	26%	100%
Q96TL5	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	24%	100%
Q9BWU1	Homo sapiens	23%	85%
Q9C9M7	Arabidopsis thaliana	26%	100%
Q9C9U2	Arabidopsis thaliana	26%	100%
Q9LMM5	Arabidopsis thaliana	28%	100%
Q9LMT0	Arabidopsis thaliana	24%	100%
Q9M1Z5	Arabidopsis thaliana	27%	100%
Q9UV50	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	26%	100%
Q9UV51	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	24%	100%
Q9VT57	Drosophila melanogaster	23%	94%
V5B9Y9	Trypanosoma cruzi	28%	94%
V5BCN4	Trypanosoma cruzi	25%	69%
V5BLT9	Trypanosoma cruzi	24%	100%
V5BR38	Trypanosoma cruzi	27%	88%
V5CZ20	Trypanosoma cruzi	27%	100%
V5DA09	Trypanosoma cruzi	20%	100%
V5DBX9	Trypanosoma cruzi	25%	75%
V5DCD4	Trypanosoma cruzi	25%	73%
V5DCN7	Trypanosoma cruzi	38%	72%
V5DDT1	Trypanosoma cruzi	26%	100%
V5DTI8	Trypanosoma cruzi	26%	100%