LeishMANIAdb
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TPR_REGION domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
TPR_REGION domain-containing protein
Gene product:
UDP-glucose:glycoprotein glucosyltransferase, putative
Species:
Leishmania major
UniProt:
E9AE73_LEIMA
TriTrypDb:
LmjF.29.2110 * , LMJLV39_290029100 * , LMJSD75_290029200 *
Length:
1757

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 10
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 8
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 6, no: 4
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005783 endoplasmic reticulum 5 2
GO:0005788 endoplasmic reticulum lumen 5 11
GO:0031974 membrane-enclosed lumen 2 11
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043231 intracellular membrane-bounded organelle 4 2
GO:0043233 organelle lumen 3 11
GO:0070013 intracellular organelle lumen 4 11
GO:0110165 cellular anatomical entity 1 11

Expansion

Sequence features

E9AE73
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006486 protein glycosylation 4 11
GO:0006487 protein N-linked glycosylation 5 2
GO:0006508 proteolysis 4 2
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins 6 2
GO:0006807 nitrogen compound metabolic process 2 11
GO:0006950 response to stress 2 2
GO:0008152 metabolic process 1 11
GO:0009056 catabolic process 2 2
GO:0009057 macromolecule catabolic process 4 2
GO:0009987 cellular process 1 2
GO:0010033 response to organic substance 3 2
GO:0010243 response to organonitrogen compound 4 2
GO:0010498 proteasomal protein catabolic process 5 2
GO:0018279 protein N-linked glycosylation via asparagine 6 2
GO:0019538 protein metabolic process 3 11
GO:0030163 protein catabolic process 4 2
GO:0033554 cellular response to stress 3 2
GO:0034976 response to endoplasmic reticulum stress 4 2
GO:0036211 protein modification process 4 11
GO:0036503 ERAD pathway 5 2
GO:0042221 response to chemical 2 2
GO:0043170 macromolecule metabolic process 3 11
GO:0043412 macromolecule modification 4 11
GO:0043413 macromolecule glycosylation 3 11
GO:0044238 primary metabolic process 2 11
GO:0050896 response to stimulus 1 2
GO:0051603 proteolysis involved in protein catabolic process 5 2
GO:0051716 cellular response to stimulus 2 2
GO:0070085 glycosylation 2 11
GO:0071704 organic substance metabolic process 2 11
GO:0071712 ER-associated misfolded protein catabolic process 6 2
GO:1901564 organonitrogen compound metabolic process 3 11
GO:1901565 organonitrogen compound catabolic process 4 2
GO:1901575 organic substance catabolic process 3 2
GO:1901698 response to nitrogen compound 3 2
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 11
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity 6 11
GO:0005488 binding 1 2
GO:0005515 protein binding 2 2
GO:0008194 UDP-glycosyltransferase activity 4 11
GO:0016740 transferase activity 2 11
GO:0016757 glycosyltransferase activity 3 11
GO:0016758 hexosyltransferase activity 4 11
GO:0035251 UDP-glucosyltransferase activity 5 11
GO:0046527 glucosyltransferase activity 5 11
GO:0051082 unfolded protein binding 3 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1086 1090 PF00656 0.559
CLV_C14_Caspase3-7 1095 1099 PF00656 0.385
CLV_C14_Caspase3-7 1186 1190 PF00656 0.461
CLV_C14_Caspase3-7 1459 1463 PF00656 0.427
CLV_C14_Caspase3-7 1740 1744 PF00656 0.290
CLV_C14_Caspase3-7 351 355 PF00656 0.639
CLV_C14_Caspase3-7 49 53 PF00656 0.313
CLV_C14_Caspase3-7 66 70 PF00656 0.272
CLV_C14_Caspase3-7 726 730 PF00656 0.289
CLV_NRD_NRD_1 1556 1558 PF00675 0.530
CLV_NRD_NRD_1 1649 1651 PF00675 0.452
CLV_NRD_NRD_1 434 436 PF00675 0.540
CLV_NRD_NRD_1 513 515 PF00675 0.430
CLV_NRD_NRD_1 619 621 PF00675 0.449
CLV_NRD_NRD_1 769 771 PF00675 0.492
CLV_NRD_NRD_1 960 962 PF00675 0.508
CLV_PCSK_FUR_1 596 600 PF00082 0.446
CLV_PCSK_KEX2_1 1524 1526 PF00082 0.530
CLV_PCSK_KEX2_1 1649 1651 PF00082 0.465
CLV_PCSK_KEX2_1 190 192 PF00082 0.572
CLV_PCSK_KEX2_1 360 362 PF00082 0.586
CLV_PCSK_KEX2_1 434 436 PF00082 0.490
CLV_PCSK_KEX2_1 513 515 PF00082 0.513
CLV_PCSK_KEX2_1 558 560 PF00082 0.396
CLV_PCSK_KEX2_1 598 600 PF00082 0.444
CLV_PCSK_KEX2_1 619 621 PF00082 0.465
CLV_PCSK_KEX2_1 769 771 PF00082 0.530
CLV_PCSK_KEX2_1 960 962 PF00082 0.475
CLV_PCSK_PC1ET2_1 1524 1526 PF00082 0.530
CLV_PCSK_PC1ET2_1 190 192 PF00082 0.572
CLV_PCSK_PC1ET2_1 360 362 PF00082 0.465
CLV_PCSK_PC1ET2_1 558 560 PF00082 0.426
CLV_PCSK_PC1ET2_1 598 600 PF00082 0.446
CLV_PCSK_SKI1_1 106 110 PF00082 0.492
CLV_PCSK_SKI1_1 1334 1338 PF00082 0.390
CLV_PCSK_SKI1_1 1461 1465 PF00082 0.429
CLV_PCSK_SKI1_1 1563 1567 PF00082 0.435
CLV_PCSK_SKI1_1 1577 1581 PF00082 0.435
CLV_PCSK_SKI1_1 1652 1656 PF00082 0.472
CLV_PCSK_SKI1_1 468 472 PF00082 0.573
CLV_PCSK_SKI1_1 494 498 PF00082 0.448
CLV_PCSK_SKI1_1 513 517 PF00082 0.409
CLV_PCSK_SKI1_1 620 624 PF00082 0.479
CLV_PCSK_SKI1_1 74 78 PF00082 0.524
CLV_PCSK_SKI1_1 799 803 PF00082 0.498
CLV_PCSK_SKI1_1 80 84 PF00082 0.482
DEG_APCC_DBOX_1 619 627 PF00400 0.258
DEG_APCC_DBOX_1 633 641 PF00400 0.269
DEG_APCC_DBOX_1 959 967 PF00400 0.370
DEG_Nend_Nbox_1 1 3 PF02207 0.280
DEG_SPOP_SBC_1 946 950 PF00917 0.361
DOC_ANK_TNKS_1 1390 1397 PF00023 0.206
DOC_CKS1_1 183 188 PF01111 0.279
DOC_CKS1_1 613 618 PF01111 0.362
DOC_CYCLIN_RxL_1 102 112 PF00134 0.190
DOC_CYCLIN_RxL_1 1557 1568 PF00134 0.235
DOC_CYCLIN_yClb1_LxF_4 620 626 PF00134 0.246
DOC_CYCLIN_yClb1_LxF_4 706 712 PF00134 0.230
DOC_MAPK_DCC_7 596 606 PF00069 0.246
DOC_MAPK_gen_1 1332 1339 PF00069 0.190
DOC_MAPK_gen_1 1419 1427 PF00069 0.246
DOC_MAPK_gen_1 1710 1718 PF00069 0.265
DOC_MAPK_gen_1 596 606 PF00069 0.245
DOC_MAPK_gen_1 619 625 PF00069 0.248
DOC_MAPK_MEF2A_6 1075 1082 PF00069 0.507
DOC_MAPK_MEF2A_6 1188 1196 PF00069 0.356
DOC_MAPK_MEF2A_6 1419 1427 PF00069 0.357
DOC_MAPK_MEF2A_6 1563 1571 PF00069 0.235
DOC_MAPK_MEF2A_6 228 235 PF00069 0.279
DOC_MAPK_MEF2A_6 598 606 PF00069 0.246
DOC_MAPK_MEF2A_6 704 712 PF00069 0.314
DOC_PP1_RVXF_1 1019 1025 PF00149 0.307
DOC_PP1_RVXF_1 1206 1212 PF00149 0.223
DOC_PP1_RVXF_1 1449 1455 PF00149 0.339
DOC_PP1_RVXF_1 1507 1513 PF00149 0.235
DOC_PP1_RVXF_1 1531 1537 PF00149 0.246
DOC_PP1_RVXF_1 1561 1567 PF00149 0.238
DOC_PP1_RVXF_1 1575 1581 PF00149 0.248
DOC_PP1_RVXF_1 405 411 PF00149 0.248
DOC_PP2B_LxvP_1 1065 1068 PF13499 0.342
DOC_PP2B_LxvP_1 54 57 PF13499 0.246
DOC_PP4_FxxP_1 1518 1521 PF00568 0.235
DOC_PP4_FxxP_1 1692 1695 PF00568 0.290
DOC_PP4_FxxP_1 771 774 PF00568 0.279
DOC_PP4_FxxP_1 96 99 PF00568 0.279
DOC_SPAK_OSR1_1 770 774 PF12202 0.246
DOC_USP7_MATH_1 1076 1080 PF00917 0.357
DOC_USP7_MATH_1 1122 1126 PF00917 0.597
DOC_USP7_MATH_1 1397 1401 PF00917 0.307
DOC_USP7_MATH_1 1456 1460 PF00917 0.536
DOC_USP7_MATH_1 1617 1621 PF00917 0.279
DOC_USP7_MATH_1 203 207 PF00917 0.343
DOC_USP7_MATH_1 211 215 PF00917 0.334
DOC_USP7_MATH_1 264 268 PF00917 0.259
DOC_USP7_MATH_1 298 302 PF00917 0.551
DOC_USP7_MATH_1 479 483 PF00917 0.308
DOC_USP7_MATH_1 57 61 PF00917 0.314
DOC_USP7_MATH_1 579 583 PF00917 0.377
DOC_USP7_MATH_1 791 795 PF00917 0.262
DOC_USP7_MATH_1 906 910 PF00917 0.372
DOC_USP7_MATH_1 929 933 PF00917 0.360
DOC_USP7_MATH_1 946 950 PF00917 0.505
DOC_USP7_MATH_1 969 973 PF00917 0.452
DOC_USP7_UBL2_3 1612 1616 PF12436 0.246
DOC_USP7_UBL2_3 1708 1712 PF12436 0.238
DOC_WW_Pin1_4 1011 1016 PF00397 0.525
DOC_WW_Pin1_4 116 121 PF00397 0.235
DOC_WW_Pin1_4 1229 1234 PF00397 0.518
DOC_WW_Pin1_4 134 139 PF00397 0.235
DOC_WW_Pin1_4 1427 1432 PF00397 0.297
DOC_WW_Pin1_4 1461 1466 PF00397 0.554
DOC_WW_Pin1_4 1517 1522 PF00397 0.235
DOC_WW_Pin1_4 1604 1609 PF00397 0.238
DOC_WW_Pin1_4 182 187 PF00397 0.279
DOC_WW_Pin1_4 239 244 PF00397 0.236
DOC_WW_Pin1_4 302 307 PF00397 0.461
DOC_WW_Pin1_4 55 60 PF00397 0.275
DOC_WW_Pin1_4 612 617 PF00397 0.317
DOC_WW_Pin1_4 662 667 PF00397 0.265
DOC_WW_Pin1_4 847 852 PF00397 0.402
DOC_WW_Pin1_4 947 952 PF00397 0.381
LIG_14-3-3_CanoR_1 1007 1015 PF00244 0.363
LIG_14-3-3_CanoR_1 1075 1081 PF00244 0.298
LIG_14-3-3_CanoR_1 1208 1212 PF00244 0.281
LIG_14-3-3_CanoR_1 1291 1295 PF00244 0.348
LIG_14-3-3_CanoR_1 1301 1306 PF00244 0.334
LIG_14-3-3_CanoR_1 1344 1351 PF00244 0.304
LIG_14-3-3_CanoR_1 1421 1426 PF00244 0.329
LIG_14-3-3_CanoR_1 1551 1559 PF00244 0.329
LIG_14-3-3_CanoR_1 158 165 PF00244 0.268
LIG_14-3-3_CanoR_1 478 486 PF00244 0.261
LIG_14-3-3_CanoR_1 513 519 PF00244 0.279
LIG_14-3-3_CanoR_1 559 566 PF00244 0.407
LIG_14-3-3_CanoR_1 634 638 PF00244 0.246
LIG_14-3-3_CanoR_1 80 89 PF00244 0.286
LIG_14-3-3_CanoR_1 840 846 PF00244 0.531
LIG_14-3-3_CanoR_1 921 925 PF00244 0.344
LIG_14-3-3_CanoR_1 947 951 PF00244 0.587
LIG_14-3-3_CanoR_1 955 960 PF00244 0.486
LIG_14-3-3_CanoR_1 961 970 PF00244 0.407
LIG_Actin_WH2_2 174 192 PF00022 0.279
LIG_Actin_WH2_2 801 816 PF00022 0.317
LIG_ActinCP_CPI_1 1645 1666 PF01115 0.329
LIG_AP2alpha_2 163 165 PF02296 0.222
LIG_BIR_III_2 1462 1466 PF00653 0.424
LIG_BRCT_BRCA1_1 1078 1082 PF00533 0.309
LIG_BRCT_BRCA1_1 1109 1113 PF00533 0.371
LIG_BRCT_BRCA1_1 1291 1295 PF00533 0.277
LIG_BRCT_BRCA1_1 1519 1523 PF00533 0.235
LIG_BRCT_BRCA1_1 1619 1623 PF00533 0.279
LIG_BRCT_BRCA1_1 1640 1644 PF00533 0.329
LIG_BRCT_BRCA1_1 481 485 PF00533 0.248
LIG_BRCT_BRCA1_1 664 668 PF00533 0.246
LIG_BRCT_BRCA1_1 77 81 PF00533 0.279
LIG_Clathr_ClatBox_1 1570 1574 PF01394 0.248
LIG_CSL_BTD_1 1547 1550 PF09270 0.329
LIG_CSL_BTD_1 54 57 PF09270 0.279
LIG_CSL_BTD_1 663 666 PF09270 0.279
LIG_CtBP_PxDLS_1 139 143 PF00389 0.244
LIG_DCNL_PONY_1 1 4 PF03556 0.281
LIG_deltaCOP1_diTrp_1 1696 1704 PF00928 0.235
LIG_deltaCOP1_diTrp_1 36 42 PF00928 0.369
LIG_deltaCOP1_diTrp_1 661 668 PF00928 0.314
LIG_DLG_GKlike_1 291 299 PF00625 0.297
LIG_FHA_1 1068 1074 PF00498 0.289
LIG_FHA_1 1178 1184 PF00498 0.393
LIG_FHA_1 1208 1214 PF00498 0.366
LIG_FHA_1 1259 1265 PF00498 0.431
LIG_FHA_1 1291 1297 PF00498 0.386
LIG_FHA_1 1309 1315 PF00498 0.361
LIG_FHA_1 1434 1440 PF00498 0.594
LIG_FHA_1 1462 1468 PF00498 0.439
LIG_FHA_1 1470 1476 PF00498 0.272
LIG_FHA_1 1505 1511 PF00498 0.235
LIG_FHA_1 1713 1719 PF00498 0.235
LIG_FHA_1 313 319 PF00498 0.355
LIG_FHA_1 421 427 PF00498 0.279
LIG_FHA_1 438 444 PF00498 0.169
LIG_FHA_1 467 473 PF00498 0.340
LIG_FHA_1 519 525 PF00498 0.403
LIG_FHA_1 540 546 PF00498 0.399
LIG_FHA_1 703 709 PF00498 0.190
LIG_FHA_1 81 87 PF00498 0.314
LIG_FHA_1 874 880 PF00498 0.349
LIG_FHA_1 885 891 PF00498 0.346
LIG_FHA_1 917 923 PF00498 0.307
LIG_FHA_1 981 987 PF00498 0.442
LIG_FHA_2 1496 1502 PF00498 0.235
LIG_FHA_2 158 164 PF00498 0.375
LIG_FHA_2 340 346 PF00498 0.582
LIG_FHA_2 724 730 PF00498 0.308
LIG_FHA_2 893 899 PF00498 0.346
LIG_Integrin_isoDGR_2 1044 1046 PF01839 0.327
LIG_LIR_Apic_2 1516 1521 PF02991 0.235
LIG_LIR_Apic_2 1542 1546 PF02991 0.235
LIG_LIR_Apic_2 300 306 PF02991 0.481
LIG_LIR_Apic_2 575 581 PF02991 0.397
LIG_LIR_Apic_2 93 99 PF02991 0.279
LIG_LIR_Gen_1 1079 1088 PF02991 0.348
LIG_LIR_Gen_1 1250 1259 PF02991 0.501
LIG_LIR_Gen_1 1269 1277 PF02991 0.355
LIG_LIR_Gen_1 1485 1495 PF02991 0.235
LIG_LIR_Gen_1 163 173 PF02991 0.279
LIG_LIR_Gen_1 1663 1671 PF02991 0.291
LIG_LIR_Gen_1 209 220 PF02991 0.300
LIG_LIR_Gen_1 391 401 PF02991 0.401
LIG_LIR_Gen_1 45 56 PF02991 0.302
LIG_LIR_Gen_1 819 825 PF02991 0.236
LIG_LIR_Nem_3 1141 1147 PF02991 0.546
LIG_LIR_Nem_3 1269 1273 PF02991 0.419
LIG_LIR_Nem_3 1520 1526 PF02991 0.252
LIG_LIR_Nem_3 1537 1543 PF02991 0.235
LIG_LIR_Nem_3 163 168 PF02991 0.329
LIG_LIR_Nem_3 1663 1667 PF02991 0.259
LIG_LIR_Nem_3 209 215 PF02991 0.300
LIG_LIR_Nem_3 322 326 PF02991 0.397
LIG_LIR_Nem_3 381 386 PF02991 0.377
LIG_LIR_Nem_3 391 396 PF02991 0.337
LIG_LIR_Nem_3 45 51 PF02991 0.260
LIG_LIR_Nem_3 497 502 PF02991 0.256
LIG_LIR_Nem_3 594 600 PF02991 0.233
LIG_LIR_Nem_3 661 667 PF02991 0.352
LIG_LIR_Nem_3 819 824 PF02991 0.236
LIG_LYPXL_yS_3 383 386 PF13949 0.340
LIG_MLH1_MIPbox_1 481 485 PF16413 0.246
LIG_MYND_3 1726 1730 PF01753 0.279
LIG_NRBOX 1208 1214 PF00104 0.421
LIG_NRBOX 603 609 PF00104 0.314
LIG_NRBOX 711 717 PF00104 0.298
LIG_PCNA_PIPBox_1 1588 1597 PF02747 0.231
LIG_PCNA_yPIPBox_3 1588 1602 PF02747 0.314
LIG_Pex14_1 1624 1628 PF04695 0.235
LIG_Pex14_1 664 668 PF04695 0.246
LIG_Pex14_2 1024 1028 PF04695 0.338
LIG_Pex14_2 1536 1540 PF04695 0.248
LIG_Pex14_2 1609 1613 PF04695 0.279
LIG_Pex14_2 485 489 PF04695 0.329
LIG_Pex14_2 625 629 PF04695 0.230
LIG_PTB_Apo_2 1096 1103 PF02174 0.440
LIG_PTB_Apo_2 317 324 PF02174 0.385
LIG_PTB_Apo_2 621 628 PF02174 0.329
LIG_PTB_Phospho_1 317 323 PF10480 0.363
LIG_REV1ctd_RIR_1 1099 1109 PF16727 0.368
LIG_SH2_CRK 1227 1231 PF00017 0.392
LIG_SH2_CRK 1562 1566 PF00017 0.235
LIG_SH2_CRK 237 241 PF00017 0.235
LIG_SH2_CRK 578 582 PF00017 0.390
LIG_SH2_CRK 697 701 PF00017 0.190
LIG_SH2_CRK 821 825 PF00017 0.329
LIG_SH2_CRK 88 92 PF00017 0.265
LIG_SH2_CRK 956 960 PF00017 0.480
LIG_SH2_NCK_1 126 130 PF00017 0.246
LIG_SH2_NCK_1 578 582 PF00017 0.390
LIG_SH2_PTP2 1526 1529 PF00017 0.329
LIG_SH2_SRC 1227 1230 PF00017 0.399
LIG_SH2_SRC 31 34 PF00017 0.279
LIG_SH2_SRC 578 581 PF00017 0.390
LIG_SH2_SRC 856 859 PF00017 0.502
LIG_SH2_SRC 862 865 PF00017 0.346
LIG_SH2_STAP1 1484 1488 PF00017 0.235
LIG_SH2_STAP1 169 173 PF00017 0.329
LIG_SH2_STAP1 449 453 PF00017 0.265
LIG_SH2_STAP1 821 825 PF00017 0.219
LIG_SH2_STAP1 864 868 PF00017 0.432
LIG_SH2_STAT3 1199 1202 PF00017 0.355
LIG_SH2_STAT3 1358 1361 PF00017 0.329
LIG_SH2_STAT5 1199 1202 PF00017 0.312
LIG_SH2_STAT5 1229 1232 PF00017 0.416
LIG_SH2_STAT5 1368 1371 PF00017 0.307
LIG_SH2_STAT5 1422 1425 PF00017 0.358
LIG_SH2_STAT5 1526 1529 PF00017 0.329
LIG_SH2_STAT5 1684 1687 PF00017 0.329
LIG_SH2_STAT5 169 172 PF00017 0.329
LIG_SH2_STAT5 272 275 PF00017 0.329
LIG_SH2_STAT5 425 428 PF00017 0.265
LIG_SH2_STAT5 556 559 PF00017 0.426
LIG_SH2_STAT5 612 615 PF00017 0.358
LIG_SH2_STAT5 856 859 PF00017 0.470
LIG_SH2_STAT5 862 865 PF00017 0.333
LIG_SH2_STAT5 956 959 PF00017 0.506
LIG_SH2_STAT5 962 965 PF00017 0.450
LIG_SH3_1 1684 1690 PF00018 0.190
LIG_SH3_1 171 177 PF00018 0.246
LIG_SH3_1 237 243 PF00018 0.230
LIG_SH3_1 541 547 PF00018 0.366
LIG_SH3_2 1465 1470 PF14604 0.517
LIG_SH3_2 174 179 PF14604 0.190
LIG_SH3_3 114 120 PF00018 0.290
LIG_SH3_3 1169 1175 PF00018 0.480
LIG_SH3_3 1179 1185 PF00018 0.369
LIG_SH3_3 1216 1222 PF00018 0.371
LIG_SH3_3 1227 1233 PF00018 0.387
LIG_SH3_3 1241 1247 PF00018 0.382
LIG_SH3_3 1261 1267 PF00018 0.255
LIG_SH3_3 1462 1468 PF00018 0.501
LIG_SH3_3 1566 1572 PF00018 0.235
LIG_SH3_3 1684 1690 PF00018 0.190
LIG_SH3_3 171 177 PF00018 0.262
LIG_SH3_3 180 186 PF00018 0.230
LIG_SH3_3 237 243 PF00018 0.230
LIG_SH3_3 541 547 PF00018 0.366
LIG_SH3_3 610 616 PF00018 0.295
LIG_SH3_3 771 777 PF00018 0.362
LIG_SH3_3 836 842 PF00018 0.371
LIG_SH3_3 876 882 PF00018 0.454
LIG_SH3_3 922 928 PF00018 0.433
LIG_SUMO_SIM_anti_2 469 474 PF11976 0.262
LIG_SUMO_SIM_par_1 1179 1184 PF11976 0.370
LIG_SUMO_SIM_par_1 1411 1417 PF11976 0.236
LIG_SUMO_SIM_par_1 1571 1576 PF11976 0.248
LIG_SUMO_SIM_par_1 202 209 PF11976 0.331
LIG_SUMO_SIM_par_1 277 282 PF11976 0.279
LIG_SUMO_SIM_par_1 564 570 PF11976 0.337
LIG_TRAF2_1 1161 1164 PF00917 0.455
LIG_TRAF2_1 1236 1239 PF00917 0.354
LIG_TRAF2_1 899 902 PF00917 0.413
LIG_TRFH_1 1211 1215 PF08558 0.225
LIG_TYR_ITIM 1366 1371 PF00017 0.291
LIG_TYR_ITIM 695 700 PF00017 0.206
LIG_TYR_ITIM 86 91 PF00017 0.380
LIG_UBA3_1 511 516 PF00899 0.328
LIG_UBA3_1 712 720 PF00899 0.262
LIG_WRC_WIRS_1 1415 1420 PF05994 0.269
LIG_WRC_WIRS_1 212 217 PF05994 0.285
MOD_CDK_SPK_2 947 952 PF00069 0.381
MOD_CDK_SPxxK_3 1517 1524 PF00069 0.269
MOD_CDK_SPxxK_3 612 619 PF00069 0.285
MOD_CK1_1 1006 1012 PF00069 0.509
MOD_CK1_1 1400 1406 PF00069 0.384
MOD_CK1_1 1433 1439 PF00069 0.522
MOD_CK1_1 1477 1483 PF00069 0.277
MOD_CK1_1 1706 1712 PF00069 0.402
MOD_CK1_1 256 262 PF00069 0.456
MOD_CK1_1 633 639 PF00069 0.330
MOD_CK1_1 67 73 PF00069 0.397
MOD_CK1_1 683 689 PF00069 0.265
MOD_CK1_1 923 929 PF00069 0.455
MOD_CK2_1 1367 1373 PF00069 0.330
MOD_CK2_1 138 144 PF00069 0.421
MOD_CK2_1 1690 1696 PF00069 0.247
MOD_CK2_1 203 209 PF00069 0.330
MOD_CK2_1 21 27 PF00069 0.432
MOD_CK2_1 386 392 PF00069 0.396
MOD_CK2_1 424 430 PF00069 0.388
MOD_CK2_1 528 534 PF00069 0.476
MOD_CK2_1 864 870 PF00069 0.294
MOD_CK2_1 892 898 PF00069 0.379
MOD_CMANNOS 1545 1548 PF00535 0.269
MOD_DYRK1A_RPxSP_1 116 120 PF00069 0.347
MOD_DYRK1A_RPxSP_1 182 186 PF00069 0.330
MOD_DYRK1A_RPxSP_1 947 951 PF00069 0.383
MOD_GlcNHglycan 1034 1037 PF01048 0.493
MOD_GlcNHglycan 1054 1057 PF01048 0.194
MOD_GlcNHglycan 1060 1063 PF01048 0.280
MOD_GlcNHglycan 1126 1129 PF01048 0.561
MOD_GlcNHglycan 1168 1171 PF01048 0.578
MOD_GlcNHglycan 1238 1243 PF01048 0.511
MOD_GlcNHglycan 1340 1343 PF01048 0.382
MOD_GlcNHglycan 1479 1482 PF01048 0.269
MOD_GlcNHglycan 154 157 PF01048 0.493
MOD_GlcNHglycan 1640 1643 PF01048 0.269
MOD_GlcNHglycan 262 265 PF01048 0.417
MOD_GlcNHglycan 266 269 PF01048 0.371
MOD_GlcNHglycan 481 484 PF01048 0.325
MOD_GlcNHglycan 530 533 PF01048 0.449
MOD_GlcNHglycan 66 69 PF01048 0.380
MOD_GlcNHglycan 682 685 PF01048 0.428
MOD_GlcNHglycan 77 80 PF01048 0.348
MOD_GlcNHglycan 809 812 PF01048 0.377
MOD_GlcNHglycan 821 824 PF01048 0.265
MOD_GlcNHglycan 864 867 PF01048 0.421
MOD_GlcNHglycan 971 974 PF01048 0.378
MOD_GSK3_1 1006 1013 PF00069 0.563
MOD_GSK3_1 1249 1256 PF00069 0.494
MOD_GSK3_1 1285 1292 PF00069 0.444
MOD_GSK3_1 1301 1308 PF00069 0.295
MOD_GSK3_1 1309 1316 PF00069 0.275
MOD_GSK3_1 1323 1330 PF00069 0.420
MOD_GSK3_1 1338 1345 PF00069 0.377
MOD_GSK3_1 134 141 PF00069 0.316
MOD_GSK3_1 1429 1436 PF00069 0.506
MOD_GSK3_1 1491 1498 PF00069 0.269
MOD_GSK3_1 1708 1715 PF00069 0.402
MOD_GSK3_1 1749 1756 PF00069 0.420
MOD_GSK3_1 21 28 PF00069 0.296
MOD_GSK3_1 256 263 PF00069 0.321
MOD_GSK3_1 298 305 PF00069 0.552
MOD_GSK3_1 333 340 PF00069 0.539
MOD_GSK3_1 346 353 PF00069 0.559
MOD_GSK3_1 420 427 PF00069 0.285
MOD_GSK3_1 5 12 PF00069 0.413
MOD_GSK3_1 514 521 PF00069 0.349
MOD_GSK3_1 557 564 PF00069 0.406
MOD_GSK3_1 63 70 PF00069 0.439
MOD_GSK3_1 730 737 PF00069 0.333
MOD_GSK3_1 841 848 PF00069 0.511
MOD_GSK3_1 873 880 PF00069 0.397
MOD_GSK3_1 916 923 PF00069 0.468
MOD_N-GLC_1 1011 1016 PF02516 0.491
MOD_N-GLC_1 1397 1402 PF02516 0.279
MOD_N-GLC_1 1403 1408 PF02516 0.261
MOD_N-GLC_1 1505 1510 PF02516 0.259
MOD_N-GLC_1 1747 1752 PF02516 0.468
MOD_N-GLC_1 25 30 PF02516 0.448
MOD_N-GLC_1 430 435 PF02516 0.357
MOD_NEK2_1 1050 1055 PF00069 0.495
MOD_NEK2_1 1101 1106 PF00069 0.361
MOD_NEK2_1 1152 1157 PF00069 0.501
MOD_NEK2_1 1200 1205 PF00069 0.306
MOD_NEK2_1 1237 1242 PF00069 0.495
MOD_NEK2_1 1285 1290 PF00069 0.477
MOD_NEK2_1 1294 1299 PF00069 0.386
MOD_NEK2_1 1327 1332 PF00069 0.316
MOD_NEK2_1 133 138 PF00069 0.420
MOD_NEK2_1 1491 1496 PF00069 0.269
MOD_NEK2_1 1749 1754 PF00069 0.502
MOD_NEK2_1 420 425 PF00069 0.356
MOD_NEK2_1 699 704 PF00069 0.206
MOD_NEK2_1 786 791 PF00069 0.465
MOD_NEK2_1 920 925 PF00069 0.474
MOD_NEK2_1 945 950 PF00069 0.533
MOD_NEK2_2 1076 1081 PF00069 0.302
MOD_NEK2_2 1108 1113 PF00069 0.461
MOD_NEK2_2 1268 1273 PF00069 0.505
MOD_NEK2_2 1290 1295 PF00069 0.289
MOD_NEK2_2 1367 1372 PF00069 0.368
MOD_NEK2_2 1456 1461 PF00069 0.354
MOD_NEK2_2 1617 1622 PF00069 0.330
MOD_NEK2_2 929 934 PF00069 0.458
MOD_PIKK_1 1115 1121 PF00454 0.540
MOD_PIKK_1 1249 1255 PF00454 0.529
MOD_PIKK_1 1271 1277 PF00454 0.521
MOD_PIKK_1 1345 1351 PF00454 0.417
MOD_PIKK_1 1403 1409 PF00454 0.373
MOD_PIKK_1 362 368 PF00454 0.606
MOD_PIKK_1 420 426 PF00454 0.356
MOD_PIKK_1 57 63 PF00454 0.285
MOD_PIKK_1 683 689 PF00454 0.307
MOD_PIKK_1 761 767 PF00454 0.269
MOD_PIKK_1 80 86 PF00454 0.269
MOD_PIKK_1 873 879 PF00454 0.449
MOD_PIKK_1 906 912 PF00454 0.389
MOD_PK_1 1133 1139 PF00069 0.357
MOD_PK_1 1301 1307 PF00069 0.295
MOD_PKA_1 558 564 PF00069 0.545
MOD_PKA_2 1006 1012 PF00069 0.528
MOD_PKA_2 1207 1213 PF00069 0.280
MOD_PKA_2 1290 1296 PF00069 0.373
MOD_PKA_2 133 139 PF00069 0.417
MOD_PKA_2 1343 1349 PF00069 0.272
MOD_PKA_2 152 158 PF00069 0.201
MOD_PKA_2 1550 1556 PF00069 0.402
MOD_PKA_2 1660 1666 PF00069 0.358
MOD_PKA_2 558 564 PF00069 0.410
MOD_PKA_2 633 639 PF00069 0.395
MOD_PKA_2 845 851 PF00069 0.432
MOD_PKA_2 920 926 PF00069 0.307
MOD_PKA_2 946 952 PF00069 0.395
MOD_PKA_2 954 960 PF00069 0.328
MOD_PKB_1 1419 1427 PF00069 0.285
MOD_Plk_1 1050 1056 PF00069 0.344
MOD_Plk_1 1133 1139 PF00069 0.418
MOD_Plk_1 1505 1511 PF00069 0.269
MOD_Plk_1 21 27 PF00069 0.452
MOD_Plk_1 291 297 PF00069 0.372
MOD_Plk_1 494 500 PF00069 0.402
MOD_Plk_1 660 666 PF00069 0.353
MOD_Plk_1 799 805 PF00069 0.257
MOD_Plk_2-3 400 406 PF00069 0.460
MOD_Plk_4 1108 1114 PF00069 0.480
MOD_Plk_4 1133 1139 PF00069 0.385
MOD_Plk_4 1177 1183 PF00069 0.400
MOD_Plk_4 1207 1213 PF00069 0.331
MOD_Plk_4 1255 1261 PF00069 0.457
MOD_Plk_4 1290 1296 PF00069 0.335
MOD_Plk_4 1301 1307 PF00069 0.271
MOD_Plk_4 1323 1329 PF00069 0.340
MOD_Plk_4 1397 1403 PF00069 0.226
MOD_Plk_4 1438 1444 PF00069 0.486
MOD_Plk_4 1749 1755 PF00069 0.499
MOD_Plk_4 26 32 PF00069 0.368
MOD_Plk_4 298 304 PF00069 0.421
MOD_Plk_4 466 472 PF00069 0.374
MOD_Plk_4 494 500 PF00069 0.402
MOD_Plk_4 514 520 PF00069 0.150
MOD_Plk_4 602 608 PF00069 0.324
MOD_Plk_4 776 782 PF00069 0.290
MOD_Plk_4 799 805 PF00069 0.343
MOD_Plk_4 892 898 PF00069 0.442
MOD_Plk_4 920 926 PF00069 0.422
MOD_Plk_4 929 935 PF00069 0.443
MOD_ProDKin_1 1011 1017 PF00069 0.521
MOD_ProDKin_1 116 122 PF00069 0.269
MOD_ProDKin_1 1229 1235 PF00069 0.520
MOD_ProDKin_1 134 140 PF00069 0.269
MOD_ProDKin_1 1427 1433 PF00069 0.356
MOD_ProDKin_1 1461 1467 PF00069 0.549
MOD_ProDKin_1 1517 1523 PF00069 0.269
MOD_ProDKin_1 1604 1610 PF00069 0.273
MOD_ProDKin_1 182 188 PF00069 0.330
MOD_ProDKin_1 239 245 PF00069 0.270
MOD_ProDKin_1 302 308 PF00069 0.460
MOD_ProDKin_1 55 61 PF00069 0.326
MOD_ProDKin_1 612 618 PF00069 0.384
MOD_ProDKin_1 662 668 PF00069 0.311
MOD_ProDKin_1 847 853 PF00069 0.398
MOD_ProDKin_1 947 953 PF00069 0.379
MOD_SUMO_for_1 1727 1730 PF00179 0.347
MOD_SUMO_for_1 679 682 PF00179 0.330
MOD_SUMO_rev_2 1141 1147 PF00179 0.455
MOD_SUMO_rev_2 1216 1222 PF00179 0.346
MOD_SUMO_rev_2 1598 1604 PF00179 0.206
MOD_SUMO_rev_2 1740 1746 PF00179 0.402
MOD_SUMO_rev_2 317 326 PF00179 0.354
MOD_SUMO_rev_2 399 408 PF00179 0.370
MOD_SUMO_rev_2 487 496 PF00179 0.350
MOD_SUMO_rev_2 714 722 PF00179 0.262
TRG_DiLeu_BaEn_1 392 397 PF01217 0.475
TRG_DiLeu_BaEn_1 507 512 PF01217 0.347
TRG_DiLeu_BaEn_4 870 876 PF01217 0.302
TRG_DiLeu_BaLyEn_6 1525 1530 PF01217 0.311
TRG_DiLeu_BaLyEn_6 219 224 PF01217 0.195
TRG_DiLeu_BaLyEn_6 87 92 PF01217 0.285
TRG_DiLeu_LyEn_5 507 512 PF01217 0.347
TRG_ENDOCYTIC_2 1227 1230 PF00928 0.347
TRG_ENDOCYTIC_2 1357 1360 PF00928 0.269
TRG_ENDOCYTIC_2 1368 1371 PF00928 0.269
TRG_ENDOCYTIC_2 1422 1425 PF00928 0.307
TRG_ENDOCYTIC_2 1484 1487 PF00928 0.269
TRG_ENDOCYTIC_2 1526 1529 PF00928 0.402
TRG_ENDOCYTIC_2 1562 1565 PF00928 0.269
TRG_ENDOCYTIC_2 1664 1667 PF00928 0.283
TRG_ENDOCYTIC_2 323 326 PF00928 0.382
TRG_ENDOCYTIC_2 383 386 PF00928 0.340
TRG_ENDOCYTIC_2 48 51 PF00928 0.269
TRG_ENDOCYTIC_2 697 700 PF00928 0.362
TRG_ENDOCYTIC_2 821 824 PF00928 0.269
TRG_ENDOCYTIC_2 88 91 PF00928 0.287
TRG_ENDOCYTIC_2 956 959 PF00928 0.482
TRG_ER_diArg_1 1418 1421 PF00400 0.411
TRG_ER_diArg_1 1648 1650 PF00400 0.336
TRG_ER_diArg_1 434 436 PF00400 0.327
TRG_ER_diArg_1 476 479 PF00400 0.363
TRG_ER_diArg_1 512 514 PF00400 0.262
TRG_ER_diArg_1 618 620 PF00400 0.347
TRG_ER_diArg_1 768 770 PF00400 0.402
TRG_ER_diArg_1 959 961 PF00400 0.488
TRG_NES_CRM1_1 1590 1600 PF08389 0.228
TRG_NES_CRM1_1 87 100 PF08389 0.307
TRG_Pf-PMV_PEXEL_1 106 110 PF00026 0.404
TRG_Pf-PMV_PEXEL_1 131 135 PF00026 0.402
TRG_Pf-PMV_PEXEL_1 1421 1426 PF00026 0.285
TRG_Pf-PMV_PEXEL_1 324 328 PF00026 0.498
TRG_Pf-PMV_PEXEL_1 80 84 PF00026 0.430

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCB9 Leptomonas seymouri 51% 97%
A0A1X0P0A1 Trypanosomatidae 34% 100%
A0A3S7X2T7 Leishmania donovani 91% 100%
A0A422NKU5 Trypanosoma rangeli 35% 100%
A4HHL1 Leishmania braziliensis 72% 98%
A4I4S1 Leishmania infantum 91% 100%
C9ZLG4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
E9ALL2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
V5DCN2 Trypanosoma cruzi 36% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS