Putative dihydrolipoamide dehydrogenase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

dihydrolipoamide dehydrogenase, putative

Species:

Leishmania major

UniProt:

E9AE44_LEIMA

TriTrypDb:

LmjF.29.1830 , LMJLV39_290025800 , LMJSD75_290026000

Length:

508

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 24

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 31
NetGPI	no	yes: 0, no: 31

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	4
GO:0032991	protein-containing complex	1	4
GO:0043226	organelle	2	4
GO:0043227	membrane-bounded organelle	3	4
GO:0043229	intracellular organelle	3	4
GO:0043231	intracellular membrane-bounded organelle	4	4
GO:0045239	tricarboxylic acid cycle enzyme complex	3	4
GO:0045240	dihydrolipoyl dehydrogenase complex	4	4
GO:0045252	oxoglutarate dehydrogenase complex	4	4
GO:0110165	cellular anatomical entity	1	4
GO:1902494	catalytic complex	2	4
GO:1990204	oxidoreductase complex	3	4
GO:1990234	transferase complex	3	4

Expansion

Sequence features

E9AE44

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AE44

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	32
GO:0019725	cellular homeostasis	2	32
GO:0042592	homeostatic process	3	32
GO:0045454	cell redox homeostasis	3	32
GO:0050789	regulation of biological process	2	32
GO:0050794	regulation of cellular process	3	32
GO:0065007	biological regulation	1	32
GO:0065008	regulation of biological quality	2	32

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	32
GO:0003824	catalytic activity	1	32
GO:0004148	dihydrolipoyl dehydrogenase activity	5	13
GO:0005488	binding	1	32
GO:0016491	oxidoreductase activity	2	32
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3	13
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4	13
GO:0036094	small molecule binding	2	32
GO:0043167	ion binding	2	32
GO:0043168	anion binding	3	32
GO:0050660	flavin adenine dinucleotide binding	4	32
GO:0097159	organic cyclic compound binding	2	32
GO:1901265	nucleoside phosphate binding	3	32
GO:1901363	heterocyclic compound binding	2	32
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3	3
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4	3
GO:0019152	acetoin dehydrogenase activity	5	3
GO:0052587	diacetyl reductase ((R)-acetoin forming) activity	6	3
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	5	5
GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	4	5
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3	5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	135	139	PF00656	0.374
CLV_C14_Caspase3-7	251	255	PF00656	0.326
CLV_C14_Caspase3-7	263	267	PF00656	0.368
CLV_NRD_NRD_1	9	11	PF00675	0.479
CLV_PCSK_KEX2_1	2	4	PF00082	0.584
CLV_PCSK_PC1ET2_1	2	4	PF00082	0.704
CLV_PCSK_SKI1_1	168	172	PF00082	0.303
CLV_PCSK_SKI1_1	327	331	PF00082	0.306
CLV_PCSK_SKI1_1	77	81	PF00082	0.305
CLV_PCSK_SKI1_1	95	99	PF00082	0.388
DEG_APCC_DBOX_1	326	334	PF00400	0.312
DEG_Nend_UBRbox_1	1	4	PF02207	0.512
DEG_SCF_FBW7_2	345	351	PF00400	0.536
DOC_CKS1_1	126	131	PF01111	0.431
DOC_CKS1_1	345	350	PF01111	0.532
DOC_MAPK_gen_1	10	16	PF00069	0.379
DOC_MAPK_gen_1	303	312	PF00069	0.411
DOC_MAPK_gen_1	419	426	PF00069	0.335
DOC_MAPK_gen_1	77	85	PF00069	0.396
DOC_MAPK_MEF2A_6	408	415	PF00069	0.318
DOC_MAPK_MEF2A_6	481	490	PF00069	0.395
DOC_MAPK_NFAT4_5	408	416	PF00069	0.435
DOC_PP1_RVXF_1	166	172	PF00149	0.384
DOC_PP1_RVXF_1	235	242	PF00149	0.327
DOC_PP1_SILK_1	477	482	PF00149	0.485
DOC_PP4_FxxP_1	126	129	PF00568	0.312
DOC_USP7_MATH_1	246	250	PF00917	0.341
DOC_USP7_MATH_1	277	281	PF00917	0.300
DOC_USP7_MATH_1	431	435	PF00917	0.325
DOC_USP7_MATH_1	54	58	PF00917	0.330
DOC_WW_Pin1_4	125	130	PF00397	0.279
DOC_WW_Pin1_4	344	349	PF00397	0.490
LIG_14-3-3_CanoR_1	392	396	PF00244	0.425
LIG_14-3-3_CanoR_1	68	72	PF00244	0.373
LIG_14-3-3_CanoR_1	77	83	PF00244	0.284
LIG_BRCT_BRCA1_1	74	78	PF00533	0.403
LIG_BRCT_BRCA1_2	74	80	PF00533	0.403
LIG_deltaCOP1_diTrp_1	492	498	PF00928	0.451
LIG_Dynein_DLC8_1	102	108	PF01221	0.431
LIG_FHA_1	104	110	PF00498	0.388
LIG_FHA_2	133	139	PF00498	0.319
LIG_FHA_2	170	176	PF00498	0.312
LIG_FHA_2	230	236	PF00498	0.449
LIG_FHA_2	258	264	PF00498	0.396
LIG_FHA_2	57	63	PF00498	0.334
LIG_HCF-1_HBM_1	343	346	PF13415	0.342
LIG_LIR_Apic_2	125	129	PF02991	0.397
LIG_LIR_Apic_2	492	496	PF02991	0.435
LIG_LIR_Gen_1	196	204	PF02991	0.327
LIG_LIR_Gen_1	307	314	PF02991	0.341
LIG_LIR_Gen_1	394	403	PF02991	0.366
LIG_LIR_Gen_1	407	415	PF02991	0.302
LIG_LIR_Nem_3	145	151	PF02991	0.340
LIG_LIR_Nem_3	196	200	PF02991	0.330
LIG_LIR_Nem_3	307	312	PF02991	0.325
LIG_LIR_Nem_3	343	349	PF02991	0.430
LIG_LIR_Nem_3	394	398	PF02991	0.388
LIG_LIR_Nem_3	407	413	PF02991	0.274
LIG_LIR_Nem_3	483	488	PF02991	0.402
LIG_LYPXL_S_1	459	463	PF13949	0.244
LIG_LYPXL_yS_3	460	463	PF13949	0.341
LIG_NRBOX	470	476	PF00104	0.479
LIG_Pex14_1	8	12	PF04695	0.338
LIG_Pex14_2	197	201	PF04695	0.325
LIG_RPA_C_Fungi	442	454	PF08784	0.441
LIG_SH2_SRC	395	398	PF00017	0.460
LIG_SH2_STAP1	393	397	PF00017	0.376
LIG_SH2_STAT5	148	151	PF00017	0.312
LIG_SH2_STAT5	259	262	PF00017	0.342
LIG_SH2_STAT5	346	349	PF00017	0.527
LIG_SH2_STAT5	397	400	PF00017	0.398
LIG_SH2_STAT5	69	72	PF00017	0.347
LIG_SUMO_SIM_anti_2	108	113	PF11976	0.365
LIG_SUMO_SIM_anti_2	184	189	PF11976	0.334
LIG_SUMO_SIM_anti_2	326	332	PF11976	0.324
LIG_SUMO_SIM_par_1	434	441	PF11976	0.318
LIG_UBA3_1	177	183	PF00899	0.319
LIG_WRC_WIRS_1	123	128	PF05994	0.441
MOD_CK1_1	125	131	PF00069	0.299
MOD_CK2_1	229	235	PF00069	0.397
MOD_CK2_1	242	248	PF00069	0.288
MOD_CK2_1	432	438	PF00069	0.325
MOD_CK2_1	56	62	PF00069	0.337
MOD_CK2_1	78	84	PF00069	0.381
MOD_Cter_Amidation	33	36	PF01082	0.455
MOD_GlcNHglycan	120	123	PF01048	0.394
MOD_GlcNHglycan	213	217	PF01048	0.458
MOD_GlcNHglycan	244	247	PF01048	0.357
MOD_GlcNHglycan	275	278	PF01048	0.379
MOD_GlcNHglycan	448	451	PF01048	0.357
MOD_GSK3_1	118	125	PF00069	0.262
MOD_GSK3_1	128	135	PF00069	0.233
MOD_GSK3_1	242	249	PF00069	0.313
MOD_GSK3_1	273	280	PF00069	0.366
MOD_GSK3_1	67	74	PF00069	0.330
MOD_N-GLC_1	359	364	PF02516	0.383
MOD_N-GLC_1	72	77	PF02516	0.367
MOD_NEK2_1	1	6	PF00069	0.606
MOD_NEK2_1	204	209	PF00069	0.349
MOD_NEK2_1	229	234	PF00069	0.395
MOD_NEK2_1	247	252	PF00069	0.267
MOD_NEK2_1	257	262	PF00069	0.360
MOD_NEK2_1	384	389	PF00069	0.444
MOD_NEK2_1	404	409	PF00069	0.262
MOD_NEK2_1	474	479	PF00069	0.346
MOD_NEK2_1	71	76	PF00069	0.436
MOD_NEK2_1	78	83	PF00069	0.368
MOD_NEK2_2	122	127	PF00069	0.407
MOD_PIKK_1	103	109	PF00454	0.403
MOD_PIKK_1	204	210	PF00454	0.431
MOD_PIKK_1	461	467	PF00454	0.337
MOD_PKA_2	103	109	PF00069	0.379
MOD_PKA_2	391	397	PF00069	0.436
MOD_PKA_2	446	452	PF00069	0.374
MOD_PKA_2	67	73	PF00069	0.366
MOD_Plk_1	140	146	PF00069	0.244
MOD_Plk_1	247	253	PF00069	0.363
MOD_Plk_1	265	271	PF00069	0.408
MOD_Plk_1	359	365	PF00069	0.315
MOD_Plk_1	40	46	PF00069	0.415
MOD_Plk_2-3	105	111	PF00069	0.429
MOD_Plk_2-3	248	254	PF00069	0.293
MOD_Plk_4	181	187	PF00069	0.341
MOD_Plk_4	196	202	PF00069	0.335
MOD_Plk_4	229	235	PF00069	0.403
MOD_Plk_4	360	366	PF00069	0.288
MOD_Plk_4	432	438	PF00069	0.347
MOD_Plk_4	475	481	PF00069	0.406
MOD_Plk_4	56	62	PF00069	0.324
MOD_Plk_4	78	84	PF00069	0.396
MOD_ProDKin_1	125	131	PF00069	0.279
MOD_ProDKin_1	344	350	PF00069	0.494
MOD_SUMO_rev_2	248	257	PF00179	0.467
TRG_DiLeu_BaEn_2	144	150	PF01217	0.360
TRG_DiLeu_BaEn_4	351	357	PF01217	0.376
TRG_ENDOCYTIC_2	148	151	PF00928	0.352
TRG_ENDOCYTIC_2	395	398	PF00928	0.360
TRG_ENDOCYTIC_2	460	463	PF00928	0.334
TRG_Pf-PMV_PEXEL_1	217	222	PF00026	0.341
TRG_Pf-PMV_PEXEL_1	58	62	PF00026	0.282

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P491	Leptomonas seymouri	31%	100%
A0A0N1HUA4	Leptomonas seymouri	40%	90%
A0A0N1I1H2	Leptomonas seymouri	24%	100%
A0A0N1IHT7	Leptomonas seymouri	81%	100%
A0A0N1IIN8	Leptomonas seymouri	39%	98%
A0A0S4J6A3	Bodo saltans	25%	100%
A0A0S4JDA8	Bodo saltans	27%	100%
A0A0S4KLJ6	Bodo saltans	55%	81%
A0A1X0NJ18	Trypanosomatidae	40%	79%
A0A1X0NK15	Trypanosomatidae	48%	87%
A0A1X0NRW2	Trypanosomatidae	29%	100%
A0A1X0NZX1	Trypanosomatidae	68%	100%
A0A1X0P0G9	Trypanosomatidae	23%	100%
A0A3Q8IDT8	Leishmania donovani	97%	100%
A0A3Q8IF30	Leishmania donovani	38%	93%
A0A3Q8ITM5	Leishmania donovani	30%	100%
A0A3R7KY91	Trypanosoma rangeli	27%	100%
A0A3R7NB58	Trypanosoma rangeli	23%	100%
A0A3R7NSH5	Trypanosoma rangeli	66%	100%
A0A3S7WP12	Leishmania donovani	22%	100%
A0A3S7X4X4	Leishmania donovani	39%	81%
A0A422NPA5	Trypanosoma rangeli	41%	82%
A0A422NPB5	Trypanosoma rangeli	46%	87%
A1AIE2	Escherichia coli O1:K1 / APEC	26%	100%
A1JI37	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	26%	100%
A1KM51	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	28%	100%
A1U1Y5	Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8)	25%	100%
A2TIL1	Callithrix jacchus	26%	97%
A4H480	Leishmania braziliensis	23%	100%
A4HIY7	Leishmania braziliensis	88%	100%
A4HJQ2	Leishmania braziliensis	38%	98%
A4HJQ3	Leishmania braziliensis	39%	69%
A4HKX6	Leishmania braziliensis	30%	100%
A4HSF7	Leishmania infantum	22%	100%
A4I4P1	Leishmania infantum	97%	100%
A4I769	Leishmania infantum	38%	100%
A4I8F6	Leishmania infantum	30%	100%
A4TRG4	Yersinia pestis (strain Pestoides F)	26%	100%
A4VMU6	Pseudomonas stutzeri (strain A1501)	26%	100%
A4WG49	Enterobacter sp. (strain 638)	26%	100%
A4XSQ1	Pseudomonas mendocina (strain ymp)	26%	100%
A5F4K5	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	28%	100%
A5U665	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	28%	100%
A5W6F5	Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)	26%	100%
A6TGE6	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	26%	100%
A6V3A6	Pseudomonas aeruginosa (strain PA7)	26%	100%
A6VW16	Marinomonas sp. (strain MWYL1)	27%	100%
A7FD10	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	26%	100%
A7ZUI2	Escherichia coli O139:H28 (strain E24377A / ETEC)	26%	100%
A8A770	Escherichia coli O9:H4 (strain HS)	26%	100%
A8AKW0	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	26%	100%
A8GL77	Serratia proteamaculans (strain 568)	25%	100%
A8MS68	Arabidopsis thaliana	26%	82%
A9N0H2	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	26%	100%
A9R6N5	Yersinia pestis bv. Antiqua (strain Angola)	26%	100%
B0KH90	Pseudomonas putida (strain GB-1)	26%	100%
B1IVB6	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	26%	100%
B1J606	Pseudomonas putida (strain W619)	25%	100%
B1JQ50	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	26%	100%
B1LNS2	Escherichia coli (strain SMS-3-5 / SECEC)	26%	100%
B1XBX3	Escherichia coli (strain K12 / DH10B)	26%	100%
B2JZF3	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	26%	100%
B2TWF7	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	26%	100%
B2VGA0	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	24%	100%
B4F1H1	Proteus mirabilis (strain HI4320)	25%	100%
B5BJN6	Salmonella paratyphi A (strain AKU_12601)	26%	100%
B5QXQ7	Salmonella enteritidis PT4 (strain P125109)	26%	100%
B5REZ6	Salmonella gallinarum (strain 287/91 / NCTC 13346)	25%	100%
B5XZ14	Klebsiella pneumoniae (strain 342)	26%	100%
B5Z064	Escherichia coli O157:H7 (strain EC4115 / EHEC)	26%	100%
B6I5I0	Escherichia coli (strain SE11)	26%	100%
B7LA64	Escherichia coli (strain 55989 / EAEC)	26%	100%
B7LUN3	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	26%	100%
B7M718	Escherichia coli O8 (strain IAI1)	26%	100%
B7MIA0	Escherichia coli O45:K1 (strain S88 / ExPEC)	26%	100%
B7MR55	Escherichia coli O81 (strain ED1a)	26%	100%
B7NFR2	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	26%	100%
B7NU38	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	26%	100%
B7UNU0	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	26%	100%
B7UZU5	Pseudomonas aeruginosa (strain LESB58)	27%	100%
B7VM91	Vibrio atlanticus (strain LGP32)	27%	100%
B9A1H3	Emiliania huxleyi	21%	100%
C0Q478	Salmonella paratyphi C (strain RKS4594)	26%	100%
C1AFH2	Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)	28%	100%
C1DR10	Azotobacter vinelandii (strain DJ / ATCC BAA-1303)	26%	100%
C3K4W1	Pseudomonas fluorescens (strain SBW25)	25%	100%
C3LPZ2	Vibrio cholerae serotype O1 (strain M66-2)	28%	100%
C4K3I8	Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)	25%	100%
C5A0R1	Escherichia coli (strain K12 / MC4100 / BW2952)	26%	100%
C9ZLC8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	67%	100%
C9ZMF4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	84%
C9ZWN2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	93%
D0A4H8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
D0AAR5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
D0VWY5	Marichromatium gracile	25%	100%
E9AHL8	Leishmania infantum	38%	93%
E9AKE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9ALP1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
E9B263	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	79%
E9B264	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	93%
E9B3B4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
F4JLP5	Arabidopsis thaliana	25%	90%
G0SB20	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	28%	100%
O00087	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	99%
O04955	Brassica rapa subsp. pekinensis	25%	100%
O05139	Pseudomonas fluorescens	25%	100%
O05940	Rhizobium etli (strain CFN 42 / ATCC 51251)	26%	100%
O08749	Mus musculus	27%	100%
O15770	Plasmodium falciparum (isolate 3D7)	23%	93%
O17953	Caenorhabditis elegans	27%	100%
O18480	Manduca sexta	27%	100%
O34324	Bacillus subtilis (strain 168)	28%	100%
O50286	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	24%	100%
O50311	Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)	27%	100%
O62768	Bos taurus	23%	100%
O84561	Chlamydia trachomatis (strain D/UW-3/Cx)	28%	100%
O89049	Rattus norvegicus	23%	100%
P00390	Homo sapiens	27%	97%
P00392	Pseudomonas aeruginosa	29%	91%
P06715	Escherichia coli (strain K12)	25%	100%
P08332	Shigella flexneri	30%	90%
P09063	Pseudomonas putida	22%	100%
P09622	Homo sapiens	27%	100%
P09623	Sus scrofa	28%	100%
P09624	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	100%
P0A0E4	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	25%	93%
P0A0E5	Staphylococcus aureus	25%	93%
P0A0E6	Staphylococcus aureus (strain Mu50 / ATCC 700699)	26%	100%
P0A0E7	Staphylococcus aureus (strain MW2)	26%	100%
P0A0E8	Staphylococcus aureus	26%	100%
P0A9P0	Escherichia coli (strain K12)	25%	100%
P0A9P1	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	25%	100%
P0A9P2	Escherichia coli O157:H7	25%	100%
P0A9P3	Shigella flexneri	25%	100%
P11959	Geobacillus stearothermophilus	30%	100%
P13110	Trypanosoma congolense	23%	100%
P14218	Pseudomonas fluorescens	26%	100%
P16171	Bacillus cereus	27%	81%
P17239	Acidithiobacillus ferrooxidans	29%	93%
P18925	Azotobacter vinelandii	25%	100%
P21880	Bacillus subtilis (strain 168)	27%	100%
P23189	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	25%	100%
P27306	Escherichia coli (strain K12)	26%	100%
P27456	Pisum sativum	25%	92%
P28593	Trypanosoma cruzi	23%	100%
P30341	Streptomyces lividans	26%	100%
P30635	Caenorhabditis elegans	25%	100%
P31023	Pisum sativum	27%	100%
P31046	Pseudomonas putida	30%	100%
P31052	Pseudomonas putida	26%	100%
P39040	Crithidia fasciculata	23%	100%
P39050	Leishmania donovani	22%	100%
P39051	Trypanosoma brucei brucei	25%	100%
P41921	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P42770	Arabidopsis thaliana	26%	90%
P43783	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	28%	100%
P43784	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	27%	100%
P47513	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	28%	100%
P47791	Mus musculus	27%	100%
P48638	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	26%	100%
P48639	Burkholderia cepacia	28%	100%
P48640	Glycine max	26%	93%
P48641	Arabidopsis thaliana	24%	100%
P48642	Oryza sativa subsp. japonica	27%	100%
P49819	Canis lupus familiaris	27%	100%
P50529	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	28%	100%
P50970	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	27%	100%
P52992	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	27%	100%
P54533	Bacillus subtilis (strain 168)	30%	100%
P57112	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	27%	100%
P57303	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	28%	100%
P61076	Plasmodium falciparum (isolate 3D7)	24%	82%
P66005	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	30%	100%
P66007	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	28%	100%
P66008	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	26%	100%
P66009	Salmonella typhi	26%	100%
P70619	Rattus norvegicus	25%	100%
P72740	Synechocystis sp. (strain PCC 6803 / Kazusa)	26%	100%
P75393	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	27%	100%
P77212	Escherichia coli (strain K12)	25%	100%
P78965	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
P80461	Nicotiana tabacum	25%	91%
P85207	Thermus scotoductus (strain ATCC 700910 / SA-01)	26%	100%
P90597	Trypanosoma cruzi	29%	100%
P91938	Drosophila melanogaster	25%	85%
P94188	Alcaligenes sp.	29%	91%
P94702	Enterobacter agglomerans	29%	91%
P95596	Rhodobacter capsulatus	28%	100%
P99084	Staphylococcus aureus (strain N315)	26%	100%
P9WHH2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	23%	100%
P9WHH3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	23%	100%
P9WHH4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	28%	100%
P9WHH5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	28%	100%
P9WHH6	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	28%	100%
P9WHH7	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	28%	100%
P9WHH8	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	30%	100%
P9WHH9	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	30%	100%
Q02733	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
Q02PF5	Pseudomonas aeruginosa (strain UCBPP-PA14)	27%	100%
Q04829	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)	25%	100%
Q04933	Trypanosoma brucei brucei	28%	100%
Q0TA96	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	26%	100%
Q16881	Homo sapiens	22%	78%
Q17745	Caenorhabditis elegans	23%	76%
Q1CBU5	Yersinia pestis bv. Antiqua (strain Antiqua)	26%	100%
Q1CNP4	Yersinia pestis bv. Antiqua (strain Nepal516)	26%	100%
Q1I7F0	Pseudomonas entomophila (strain L48)	25%	100%
Q1QX78	Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)	28%	100%
Q1R3U7	Escherichia coli (strain UTI89 / UPEC)	26%	100%
Q25861	Plasmodium falciparum (isolate FCH-5)	24%	94%
Q2NQZ3	Sodalis glossinidius (strain morsitans)	25%	100%
Q2SIP2	Hahella chejuensis (strain KCTC 2396)	26%	100%
Q3K9F5	Pseudomonas fluorescens (strain Pf0-1)	25%	100%
Q41219	Glycine max	27%	97%
Q43154	Spinacia oleracea	26%	100%
Q43621	Pisum sativum	25%	100%
Q48A14	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	24%	100%
Q48KI8	Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)	26%	100%
Q4KFA6	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	25%	100%
Q4Q4U1	Leishmania major	30%	96%
Q4Q5Z6	Leishmania major	38%	91%
Q4Q5Z7	Leishmania major	38%	82%
Q4QJG7	Leishmania major	23%	100%
Q4ZV77	Pseudomonas syringae pv. syringae (strain B728a)	26%	100%
Q50068	Mycobacterium leprae (strain TN)	29%	100%
Q51772	Pseudomonas fluorescens	29%	93%
Q52109	Acinetobacter calcoaceticus	29%	91%
Q54465	Shewanella putrefaciens	31%	91%
Q54EW8	Dictyostelium discoideum	28%	100%
Q57H91	Salmonella choleraesuis (strain SC-B67)	26%	100%
Q5E212	Aliivibrio fischeri (strain ATCC 700601 / ES114)	28%	100%
Q5HGY8	Staphylococcus aureus (strain COL)	26%	100%
Q5NVA2	Pongo abelii	22%	100%
Q5PK71	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	26%	100%
Q5R4B1	Pongo abelii	27%	100%
Q5UWH2	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	26%	100%
Q5UYG6	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	25%	100%
Q60151	Streptococcus thermophilus	24%	100%
Q60HG3	Macaca fascicularis	27%	100%
Q66G61	Yersinia pseudotuberculosis serotype I (strain IP32953)	26%	100%
Q6BPI1	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	23%	100%
Q6C5H4	Yarrowia lipolytica (strain CLIB 122 / E 150)	25%	100%
Q6CZB1	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	26%	100%
Q6FRV2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	25%	100%
Q6GAB8	Staphylococcus aureus (strain MSSA476)	26%	100%
Q6GHY9	Staphylococcus aureus (strain MRSA252)	26%	100%
Q6HA23	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	25%	100%
Q6LLT9	Photobacterium profundum (strain SS9)	26%	100%
Q6P6R2	Rattus norvegicus	26%	100%
Q74ZK4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	25%	100%
Q7MBG9	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	24%	100%
Q7MQ83	Vibrio vulnificus (strain YJ016)	27%	100%
Q811C4	Mesocricetus auratus	28%	100%
Q83MI1	Shigella flexneri	26%	100%
Q86VQ6	Homo sapiens	23%	79%
Q873E8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	27%	100%
Q87KN5	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	27%	100%
Q884I6	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	26%	100%
Q88KY8	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	26%	100%
Q89AQ8	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	26%	100%
Q8CIZ7	Cricetulus griseus	27%	100%
Q8DD46	Vibrio vulnificus (strain CMCP6)	27%	100%
Q8FB93	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	26%	100%
Q8K9T7	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	26%	100%
Q8KCW2	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	28%	100%
Q8NTE1	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	27%	100%
Q8T137	Dictyostelium discoideum	26%	100%
Q8X727	Escherichia coli O157:H7	26%	100%
Q8ZA97	Yersinia pestis	26%	100%
Q93379	Caenorhabditis elegans	26%	100%
Q94655	Plasmodium falciparum (isolate K1 / Thailand)	22%	100%
Q99MD6	Mus musculus	24%	78%
Q9HN74	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	27%	100%
Q9HUY1	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	29%	100%
Q9I1L9	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	25%	100%
Q9I3D1	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	26%	100%
Q9JLT4	Mus musculus	24%	97%
Q9JMH6	Mus musculus	23%	83%
Q9KPF6	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	25%	100%
Q9M5K2	Arabidopsis thaliana	27%	100%
Q9M5K3	Arabidopsis thaliana	28%	100%
Q9MYY8	Sus scrofa	23%	100%
Q9N2I8	Bos taurus	25%	99%
Q9NNW7	Homo sapiens	24%	97%
Q9PJI3	Chlamydia muridarum (strain MoPn / Nigg)	29%	100%
Q9SPB1	Vigna unguiculata	26%	97%
Q9VNT5	Drosophila melanogaster	22%	98%
Q9XBQ9	Azotobacter vinelandii	26%	100%
Q9Z0J5	Rattus norvegicus	23%	97%
Q9Z773	Chlamydia pneumoniae	28%	100%
V5AJG2	Trypanosoma cruzi	23%	100%
V5B6P6	Trypanosoma cruzi	48%	92%
V5BB90	Trypanosoma cruzi	41%	92%
V5BDX2	Trypanosoma cruzi	66%	100%
V5BVJ1	Trypanosoma cruzi	28%	100%