LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Secreted protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania major
UniProt:
E9AE29_LEIMA
TriTrypDb:
Length:
114

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AE29
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AE29

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 93 97 PF00656 0.543
CLV_NRD_NRD_1 66 68 PF00675 0.344
CLV_PCSK_FUR_1 64 68 PF00082 0.342
CLV_PCSK_KEX2_1 66 68 PF00082 0.344
DEG_APCC_DBOX_1 5 13 PF00400 0.400
DEG_Nend_UBRbox_4 1 3 PF02207 0.560
DOC_CDC14_PxL_1 40 48 PF14671 0.199
DOC_MAPK_DCC_7 6 15 PF00069 0.400
DOC_MAPK_gen_1 6 15 PF00069 0.400
DOC_MAPK_HePTP_8 3 15 PF00069 0.400
DOC_MAPK_MEF2A_6 6 15 PF00069 0.400
DOC_USP7_MATH_1 73 77 PF00917 0.557
DOC_WW_Pin1_4 83 88 PF00397 0.579
LIG_14-3-3_CanoR_1 32 37 PF00244 0.199
LIG_FHA_1 22 28 PF00498 0.199
LIG_FHA_1 52 58 PF00498 0.199
LIG_HP1_1 11 15 PF01393 0.199
LIG_SH2_STAT5 17 20 PF00017 0.199
LIG_SH3_3 38 44 PF00018 0.199
LIG_SH3_3 84 90 PF00018 0.572
LIG_WRC_WIRS_1 36 41 PF05994 0.199
LIG_WRC_WIRS_1 91 96 PF05994 0.549
MOD_CK1_1 35 41 PF00069 0.199
MOD_CK1_1 83 89 PF00069 0.577
MOD_CK2_1 50 56 PF00069 0.199
MOD_GlcNHglycan 71 74 PF01048 0.349
MOD_GlcNHglycan 82 85 PF01048 0.386
MOD_GSK3_1 69 76 PF00069 0.551
MOD_GSK3_1 79 86 PF00069 0.585
MOD_N-GLC_1 74 79 PF02516 0.369
MOD_NEK2_1 21 26 PF00069 0.199
MOD_NEK2_1 30 35 PF00069 0.370
MOD_OFUCOSY 16 23 PF10250 0.199
MOD_PK_1 32 38 PF00069 0.199
MOD_Plk_1 4 10 PF00069 0.539
MOD_Plk_4 35 41 PF00069 0.199
MOD_ProDKin_1 83 89 PF00069 0.577
TRG_DiLeu_BaEn_1 5 10 PF01217 0.536
TRG_DiLeu_BaLyEn_6 41 46 PF01217 0.199
TRG_DiLeu_BaLyEn_6 87 92 PF01217 0.563
TRG_DiLeu_LyEn_5 5 10 PF01217 0.536
TRG_ER_diArg_1 6 9 PF00400 0.537
TRG_ER_diArg_1 65 67 PF00400 0.546

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS