LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Secreted protein
Gene product:
hypothetical protein
Species:
Leishmania major
UniProt:
E9AE22_LEIMA
TriTrypDb:
LmjF.29.1605
Length:
78

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

E9AE22
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AE22

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_Nend_UBRbox_1 1 4 PF02207 0.787
DEG_SCF_FBW7_1 33 40 PF00400 0.582
DOC_CYCLIN_yCln2_LP_2 17 23 PF00134 0.549
DOC_MAPK_gen_1 2 10 PF00069 0.650
DOC_MAPK_MEF2A_6 4 12 PF00069 0.650
DOC_PP2B_LxvP_1 17 20 PF13499 0.549
DOC_USP7_MATH_1 37 41 PF00917 0.572
DOC_WW_Pin1_4 33 38 PF00397 0.589
LIG_14-3-3_CanoR_1 26 31 PF00244 0.598
LIG_FHA_1 25 31 PF00498 0.370
LIG_FHA_1 7 13 PF00498 0.549
LIG_LIR_Nem_3 11 17 PF02991 0.549
LIG_PDZ_Class_2 73 78 PF00595 0.789
LIG_Pex14_2 14 18 PF04695 0.549
MOD_GSK3_1 33 40 PF00069 0.582
MOD_PKA_2 25 31 PF00069 0.595
MOD_Plk_4 37 43 PF00069 0.570
MOD_ProDKin_1 33 39 PF00069 0.587
TRG_DiLeu_BaLyEn_6 17 22 PF01217 0.549
TRG_ER_diArg_1 1 4 PF00400 0.787

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS