Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ADY7_LEIMA

TriTrypDb:

LmjF.29.1290 , LMJLV39_290019300 , LMJSD75_290019400

Length:

118


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0031974	membrane-enclosed lumen	2	2
GO:0031981	nuclear lumen	5	2
GO:0043233	organelle lumen	3	2
GO:0070013	intracellular organelle lumen	4	2
GO:0110165	cellular anatomical entity	1	2

E9ADY7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ADY7


Leishmania	From	To	Domain/Motif	Score
DEG_SPOP_SBC_1	5	9	PF00917	0.712
DOC_PP1_RVXF_1	40	47	PF00149	0.565
DOC_PP2B_LxvP_1	23	26	PF13499	0.485
DOC_USP7_MATH_1	24	28	PF00917	0.466
DOC_USP7_UBL2_3	114	118	PF12436	0.548
LIG_14-3-3_CanoR_1	68	73	PF00244	0.562
LIG_BIR_II_1	1	5	PF00653	0.640
LIG_BRCT_BRCA1_1	75	79	PF00533	0.506
LIG_deltaCOP1_diTrp_1	29	35	PF00928	0.448
LIG_FHA_1	17	23	PF00498	0.526
LIG_FHA_1	6	12	PF00498	0.585
LIG_LIR_Gen_1	40	51	PF02991	0.462
LIG_LIR_Gen_1	97	107	PF02991	0.450
LIG_LIR_Nem_3	40	46	PF02991	0.442
LIG_LIR_Nem_3	97	103	PF02991	0.466
LIG_Pex14_1	32	36	PF04695	0.443
LIG_SUMO_SIM_par_1	18	30	PF11976	0.628
LIG_TRAF2_1	86	89	PF00917	0.572
LIG_TRFH_1	49	53	PF08558	0.433
LIG_WRC_WIRS_1	46	51	PF05994	0.489
MOD_CK1_1	27	33	PF00069	0.563
MOD_CK1_1	66	72	PF00069	0.530
MOD_CK2_1	4	10	PF00069	0.570
MOD_CK2_1	83	89	PF00069	0.502
MOD_CMANNOS	32	35	PF00535	0.448
MOD_GlcNHglycan	32	35	PF01048	0.508
MOD_GlcNHglycan	75	78	PF01048	0.591
MOD_GSK3_1	1	8	PF00069	0.643
MOD_GSK3_1	11	18	PF00069	0.469
MOD_GSK3_1	110	117	PF00069	0.514
MOD_GSK3_1	59	66	PF00069	0.563
MOD_N-GLC_1	59	64	PF02516	0.679
MOD_NEK2_1	1	6	PF00069	0.672
MOD_NEK2_1	110	115	PF00069	0.565
MOD_PIKK_1	105	111	PF00454	0.548
MOD_PK_1	63	69	PF00069	0.642
MOD_Plk_1	96	102	PF00069	0.471
MOD_Plk_2-3	45	51	PF00069	0.511
MOD_Plk_4	11	17	PF00069	0.657
MOD_Plk_4	27	33	PF00069	0.475
MOD_SUMO_rev_2	38	44	PF00179	0.494
MOD_SUMO_rev_2	7	14	PF00179	0.695


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I688	Leptomonas seymouri	76%	100%
A0A1X0NZR9	Trypanosomatidae	56%	84%
A0A3Q8IH91	Leishmania donovani	98%	100%
A0A3R7RKT9	Trypanosoma rangeli	52%	81%
A4HHE0	Leishmania braziliensis	91%	100%
A4I4I6	Leishmania infantum	98%	100%
C9ZL73	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	61%	86%
E9ALU4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%