DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

DNA helicase

Gene product:

tfiih basal transcription factor complex helicase xpb subunit

Species:

Leishmania major

UniProt:

E9ADR1_LEIMA

TriTrypDb:

LmjF.29.0590 , LMJLV39_290011300 , LMJSD75_290011300

Length:

1106

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0000109	nucleotide-excision repair complex	3	2
GO:0000112	nucleotide-excision repair factor 3 complex	4	2
GO:0005634	nucleus	5	2
GO:0005654	nucleoplasm	2	2
GO:0005667	transcription regulator complex	2	2
GO:0005675	transcription factor TFIIH holo complex	4	2
GO:0005737	cytoplasm	2	2
GO:0032806	carboxy-terminal domain protein kinase complex	3	2
GO:0032991	protein-containing complex	1	2
GO:0032993	protein-DNA complex	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	2
GO:0090575	RNA polymerase II transcription regulator complex	3	2
GO:0097550	transcription preinitiation complex	3	2
GO:0110165	cellular anatomical entity	1	2
GO:0140513	nuclear protein-containing complex	2	2
GO:1902494	catalytic complex	2	2
GO:1902554	serine/threonine protein kinase complex	6	2
GO:1902911	protein kinase complex	5	2
GO:1990234	transferase complex	3	2

Expansion

Sequence features

E9ADR1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ADR1

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	5
GO:0006352	DNA-templated transcription initiation	6	5
GO:0006367	transcription initiation at RNA polymerase II promoter	7	5
GO:0006725	cellular aromatic compound metabolic process	3	5
GO:0006807	nitrogen compound metabolic process	2	5
GO:0008152	metabolic process	1	5
GO:0009058	biosynthetic process	2	5
GO:0009059	macromolecule biosynthetic process	4	5
GO:0009987	cellular process	1	5
GO:0016070	RNA metabolic process	5	5
GO:0018130	heterocycle biosynthetic process	4	5
GO:0019438	aromatic compound biosynthetic process	4	5
GO:0032774	RNA biosynthetic process	5	5
GO:0033683	obsolete nucleotide-excision repair, DNA incision	6	2
GO:0034641	cellular nitrogen compound metabolic process	3	5
GO:0034654	nucleobase-containing compound biosynthetic process	4	5
GO:0043170	macromolecule metabolic process	3	5
GO:0044237	cellular metabolic process	2	5
GO:0044238	primary metabolic process	2	5
GO:0044249	cellular biosynthetic process	3	5
GO:0044271	cellular nitrogen compound biosynthetic process	4	5
GO:0046483	heterocycle metabolic process	3	5
GO:0071704	organic substance metabolic process	2	5
GO:0090304	nucleic acid metabolic process	4	5
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5	2
GO:1901360	organic cyclic compound metabolic process	3	5
GO:1901362	organic cyclic compound biosynthetic process	4	5
GO:1901576	organic substance biosynthetic process	3	5
GO:0006259	DNA metabolic process	4	3
GO:0006281	DNA repair	5	3
GO:0006289	nucleotide-excision repair	6	3
GO:0006950	response to stress	2	3
GO:0006974	DNA damage response	4	3
GO:0033554	cellular response to stress	3	3
GO:0044260	obsolete cellular macromolecule metabolic process	3	3
GO:0050896	response to stimulus	1	3
GO:0051716	cellular response to stimulus	2	3

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003676	nucleic acid binding	3	10
GO:0003677	DNA binding	4	10
GO:0003678	DNA helicase activity	3	10
GO:0003700	DNA-binding transcription factor activity	2	2
GO:0003824	catalytic activity	1	10
GO:0004386	helicase activity	2	10
GO:0005488	binding	1	10
GO:0005524	ATP binding	5	10
GO:0008094	ATP-dependent activity, acting on DNA	2	10
GO:0016787	hydrolase activity	2	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0043138	3'-5' DNA helicase activity	4	2
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:0140097	catalytic activity, acting on DNA	3	10
GO:0140110	transcription regulator activity	1	2
GO:0140640	catalytic activity, acting on a nucleic acid	2	10
GO:0140657	ATP-dependent activity	1	10
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10
GO:0016462	pyrophosphatase activity	5	1
GO:0016817	hydrolase activity, acting on acid anhydrides	3	1
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	1
GO:0016887	ATP hydrolysis activity	7	1
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1033	1037	PF00656	0.514
CLV_C14_Caspase3-7	730	734	PF00656	0.639
CLV_MEL_PAP_1	837	843	PF00089	0.274
CLV_NRD_NRD_1	1058	1060	PF00675	0.421
CLV_NRD_NRD_1	1061	1063	PF00675	0.436
CLV_NRD_NRD_1	264	266	PF00675	0.488
CLV_NRD_NRD_1	293	295	PF00675	0.582
CLV_NRD_NRD_1	491	493	PF00675	0.329
CLV_NRD_NRD_1	703	705	PF00675	0.690
CLV_NRD_NRD_1	864	866	PF00675	0.312
CLV_PCSK_FUR_1	1056	1060	PF00082	0.560
CLV_PCSK_FUR_1	291	295	PF00082	0.563
CLV_PCSK_FUR_1	489	493	PF00082	0.292
CLV_PCSK_KEX2_1	1058	1060	PF00082	0.437
CLV_PCSK_KEX2_1	1061	1063	PF00082	0.440
CLV_PCSK_KEX2_1	173	175	PF00082	0.619
CLV_PCSK_KEX2_1	264	266	PF00082	0.488
CLV_PCSK_KEX2_1	293	295	PF00082	0.580
CLV_PCSK_KEX2_1	491	493	PF00082	0.292
CLV_PCSK_KEX2_1	577	579	PF00082	0.298
CLV_PCSK_KEX2_1	703	705	PF00082	0.688
CLV_PCSK_KEX2_1	715	717	PF00082	0.650
CLV_PCSK_KEX2_1	864	866	PF00082	0.312
CLV_PCSK_KEX2_1	905	907	PF00082	0.431
CLV_PCSK_PC1ET2_1	173	175	PF00082	0.619
CLV_PCSK_PC1ET2_1	577	579	PF00082	0.333
CLV_PCSK_PC1ET2_1	715	717	PF00082	0.620
CLV_PCSK_PC1ET2_1	905	907	PF00082	0.431
CLV_PCSK_SKI1_1	219	223	PF00082	0.665
CLV_PCSK_SKI1_1	357	361	PF00082	0.481
CLV_PCSK_SKI1_1	440	444	PF00082	0.417
CLV_PCSK_SKI1_1	509	513	PF00082	0.274
CLV_PCSK_SKI1_1	539	543	PF00082	0.298
CLV_PCSK_SKI1_1	590	594	PF00082	0.364
CLV_PCSK_SKI1_1	627	631	PF00082	0.391
CLV_PCSK_SKI1_1	695	699	PF00082	0.522
CLV_Separin_Metazoa	408	412	PF03568	0.503
DEG_APCC_DBOX_1	345	353	PF00400	0.530
DEG_APCC_DBOX_1	589	597	PF00400	0.391
DEG_Nend_UBRbox_3	1	3	PF02207	0.527
DOC_ANK_TNKS_1	577	584	PF00023	0.268
DOC_CDC14_PxL_1	1017	1025	PF14671	0.535
DOC_CKS1_1	222	227	PF01111	0.606
DOC_CYCLIN_RxL_1	213	224	PF00134	0.717
DOC_CYCLIN_RxL_1	755	764	PF00134	0.336
DOC_CYCLIN_yCln2_LP_2	217	223	PF00134	0.665
DOC_MAPK_DCC_7	357	365	PF00069	0.424
DOC_MAPK_gen_1	491	502	PF00069	0.331
DOC_MAPK_gen_1	560	568	PF00069	0.391
DOC_MAPK_gen_1	625	632	PF00069	0.303
DOC_MAPK_JIP1_4	399	405	PF00069	0.630
DOC_MAPK_MEF2A_6	250	257	PF00069	0.612
DOC_MAPK_MEF2A_6	840	848	PF00069	0.274
DOC_PP1_RVXF_1	1027	1033	PF00149	0.494
DOC_PP1_RVXF_1	1079	1086	PF00149	0.403
DOC_PP1_RVXF_1	786	793	PF00149	0.274
DOC_PP2B_LxvP_1	466	469	PF13499	0.429
DOC_PP2B_LxvP_1	806	809	PF13499	0.274
DOC_PP2B_LxvP_1	846	849	PF13499	0.274
DOC_PP4_FxxP_1	359	362	PF00568	0.391
DOC_USP7_MATH_1	1010	1014	PF00917	0.516
DOC_USP7_MATH_1	118	122	PF00917	0.760
DOC_USP7_MATH_1	191	195	PF00917	0.786
DOC_USP7_MATH_1	204	208	PF00917	0.697
DOC_USP7_MATH_1	315	319	PF00917	0.756
DOC_USP7_MATH_1	421	425	PF00917	0.641
DOC_USP7_MATH_1	586	590	PF00917	0.391
DOC_USP7_MATH_1	754	758	PF00917	0.485
DOC_USP7_MATH_1	849	853	PF00917	0.274
DOC_USP7_MATH_1	898	902	PF00917	0.336
DOC_USP7_MATH_1	954	958	PF00917	0.637
DOC_WW_Pin1_4	1006	1011	PF00397	0.482
DOC_WW_Pin1_4	1050	1055	PF00397	0.503
DOC_WW_Pin1_4	152	157	PF00397	0.644
DOC_WW_Pin1_4	206	211	PF00397	0.677
DOC_WW_Pin1_4	221	226	PF00397	0.632
DOC_WW_Pin1_4	231	236	PF00397	0.698
DOC_WW_Pin1_4	376	381	PF00397	0.613
DOC_WW_Pin1_4	419	424	PF00397	0.651
DOC_WW_Pin1_4	781	786	PF00397	0.274
DOC_WW_Pin1_4	952	957	PF00397	0.659
LIG_14-3-3_CanoR_1	1011	1020	PF00244	0.599
LIG_14-3-3_CanoR_1	107	113	PF00244	0.608
LIG_14-3-3_CanoR_1	1081	1086	PF00244	0.560
LIG_14-3-3_CanoR_1	1087	1091	PF00244	0.604
LIG_14-3-3_CanoR_1	147	154	PF00244	0.560
LIG_14-3-3_CanoR_1	250	256	PF00244	0.626
LIG_14-3-3_CanoR_1	302	307	PF00244	0.744
LIG_14-3-3_CanoR_1	314	318	PF00244	0.551
LIG_14-3-3_CanoR_1	370	380	PF00244	0.472
LIG_14-3-3_CanoR_1	761	770	PF00244	0.394
LIG_14-3-3_CanoR_1	906	910	PF00244	0.315
LIG_14-3-3_CanoR_1	924	932	PF00244	0.489
LIG_APCC_ABBA_1	789	794	PF00400	0.280
LIG_APCC_ABBAyCdc20_2	718	724	PF00400	0.632
LIG_APCC_ABBAyCdc20_2	788	794	PF00400	0.274
LIG_BIR_III_4	750	754	PF00653	0.493
LIG_BRCT_BRCA1_1	118	122	PF00533	0.626
LIG_Clathr_ClatBox_1	1022	1026	PF01394	0.379
LIG_Clathr_ClatBox_1	603	607	PF01394	0.298
LIG_CtBP_PxDLS_1	268	272	PF00389	0.537
LIG_deltaCOP1_diTrp_1	1026	1032	PF00928	0.396
LIG_deltaCOP1_diTrp_1	965	974	PF00928	0.360
LIG_FHA_1	1041	1047	PF00498	0.469
LIG_FHA_1	136	142	PF00498	0.761
LIG_FHA_1	209	215	PF00498	0.691
LIG_FHA_1	324	330	PF00498	0.570
LIG_FHA_1	382	388	PF00498	0.610
LIG_FHA_1	463	469	PF00498	0.401
LIG_FHA_1	520	526	PF00498	0.392
LIG_FHA_1	54	60	PF00498	0.484
LIG_FHA_1	554	560	PF00498	0.298
LIG_FHA_1	692	698	PF00498	0.516
LIG_FHA_1	819	825	PF00498	0.352
LIG_FHA_1	895	901	PF00498	0.313
LIG_FHA_1	995	1001	PF00498	0.546
LIG_FHA_2	146	152	PF00498	0.594
LIG_FHA_2	412	418	PF00498	0.687
LIG_IBAR_NPY_1	766	768	PF08397	0.298
LIG_LIR_Apic_2	358	362	PF02991	0.401
LIG_LIR_Apic_2	972	978	PF02991	0.485
LIG_LIR_Gen_1	1031	1038	PF02991	0.469
LIG_LIR_Gen_1	444	454	PF02991	0.438
LIG_LIR_Gen_1	455	466	PF02991	0.314
LIG_LIR_Gen_1	569	576	PF02991	0.309
LIG_LIR_Gen_1	656	667	PF02991	0.371
LIG_LIR_Gen_1	927	936	PF02991	0.519
LIG_LIR_Nem_3	1031	1035	PF02991	0.452
LIG_LIR_Nem_3	1040	1044	PF02991	0.377
LIG_LIR_Nem_3	444	450	PF02991	0.412
LIG_LIR_Nem_3	455	460	PF02991	0.352
LIG_LIR_Nem_3	569	574	PF02991	0.309
LIG_LIR_Nem_3	623	629	PF02991	0.336
LIG_LIR_Nem_3	656	662	PF02991	0.362
LIG_LIR_Nem_3	687	691	PF02991	0.413
LIG_LIR_Nem_3	750	755	PF02991	0.484
LIG_LIR_Nem_3	927	932	PF02991	0.453
LIG_LIR_Nem_3	965	971	PF02991	0.495
LIG_LYPXL_SIV_4	17	25	PF13949	0.488
LIG_LYPXL_yS_3	1020	1023	PF13949	0.531
LIG_PCNA_yPIPBox_3	165	176	PF02747	0.544
LIG_Pex14_1	1028	1032	PF04695	0.388
LIG_Pex14_1	537	541	PF04695	0.274
LIG_Rb_LxCxE_1	23	39	PF01857	0.466
LIG_RPA_C_Fungi	1082	1094	PF08784	0.355
LIG_SH2_CRK	571	575	PF00017	0.274
LIG_SH2_CRK	626	630	PF00017	0.333
LIG_SH2_CRK	752	756	PF00017	0.455
LIG_SH2_CRK	890	894	PF00017	0.274
LIG_SH2_CRK	917	921	PF00017	0.298
LIG_SH2_NCK_1	416	420	PF00017	0.532
LIG_SH2_NCK_1	890	894	PF00017	0.274
LIG_SH2_SRC	18	21	PF00017	0.424
LIG_SH2_SRC	407	410	PF00017	0.581
LIG_SH2_STAP1	18	22	PF00017	0.494
LIG_SH2_STAP1	57	61	PF00017	0.443
LIG_SH2_STAP1	571	575	PF00017	0.391
LIG_SH2_STAP1	655	659	PF00017	0.356
LIG_SH2_STAT3	339	342	PF00017	0.483
LIG_SH2_STAT3	430	433	PF00017	0.379
LIG_SH2_STAT3	689	692	PF00017	0.300
LIG_SH2_STAT3	904	907	PF00017	0.298
LIG_SH2_STAT5	339	342	PF00017	0.417
LIG_SH2_STAT5	467	470	PF00017	0.418
LIG_SH2_STAT5	795	798	PF00017	0.391
LIG_SH2_STAT5	826	829	PF00017	0.274
LIG_SH2_STAT5	888	891	PF00017	0.276
LIG_SH3_2	1051	1056	PF14604	0.497
LIG_SH3_3	1032	1038	PF00018	0.481
LIG_SH3_3	1048	1054	PF00018	0.438
LIG_SH3_3	217	223	PF00018	0.732
LIG_SH3_3	254	260	PF00018	0.660
LIG_SH3_3	284	290	PF00018	0.420
LIG_SH3_3	673	679	PF00018	0.343
LIG_SH3_3	874	880	PF00018	0.321
LIG_SH3_3	936	942	PF00018	0.400
LIG_Sin3_3	983	990	PF02671	0.426
LIG_SUMO_SIM_anti_2	254	259	PF11976	0.612
LIG_SUMO_SIM_par_1	1042	1048	PF11976	0.490
LIG_SUMO_SIM_par_1	602	608	PF11976	0.274
LIG_SUMO_SIM_par_1	76	82	PF11976	0.492
LIG_TRAF2_1	1013	1016	PF00917	0.651
LIG_TRAF2_1	1076	1079	PF00917	0.488
LIG_TRAF2_1	548	551	PF00917	0.292
LIG_TRAF2_1	585	588	PF00917	0.391
LIG_TRAF2_1	73	76	PF00917	0.545
LIG_TYR_ITIM	624	629	PF00017	0.333
LIG_TYR_ITSM	567	574	PF00017	0.391
LIG_WRC_WIRS_1	1022	1027	PF05994	0.372
LIG_WW_3	408	412	PF00397	0.503
MOD_CDC14_SPxK_1	1053	1056	PF00782	0.482
MOD_CDK_SPK_2	1006	1011	PF00069	0.470
MOD_CDK_SPxK_1	1050	1056	PF00069	0.497
MOD_CDK_SPxxK_3	206	213	PF00069	0.683
MOD_CDK_SPxxK_3	231	238	PF00069	0.551
MOD_CDK_SPxxK_3	781	788	PF00069	0.274
MOD_CK1_1	1024	1030	PF00069	0.471
MOD_CK1_1	106	112	PF00069	0.706
MOD_CK1_1	167	173	PF00069	0.803
MOD_CK1_1	200	206	PF00069	0.685
MOD_CK1_1	209	215	PF00069	0.684
MOD_CK1_1	234	240	PF00069	0.660
MOD_CK1_1	305	311	PF00069	0.599
MOD_CK1_1	313	319	PF00069	0.561
MOD_CK1_1	46	52	PF00069	0.458
MOD_CK1_1	472	478	PF00069	0.395
MOD_CK1_1	894	900	PF00069	0.291
MOD_CK1_1	957	963	PF00069	0.676
MOD_CK1_1	97	103	PF00069	0.660
MOD_CK2_1	1010	1016	PF00069	0.593
MOD_CK2_1	1100	1106	PF00069	0.619
MOD_CK2_1	236	242	PF00069	0.766
MOD_CK2_1	24	30	PF00069	0.422
MOD_CK2_1	411	417	PF00069	0.634
MOD_CK2_1	731	737	PF00069	0.785
MOD_CK2_1	813	819	PF00069	0.332
MOD_Cter_Amidation	492	495	PF01082	0.279
MOD_Cter_Amidation	713	716	PF01082	0.608
MOD_GlcNHglycan	148	151	PF01048	0.613
MOD_GlcNHglycan	186	189	PF01048	0.761
MOD_GlcNHglycan	193	196	PF01048	0.787
MOD_GlcNHglycan	202	205	PF01048	0.707
MOD_GlcNHglycan	206	209	PF01048	0.681
MOD_GlcNHglycan	226	229	PF01048	0.821
MOD_GlcNHglycan	423	426	PF01048	0.578
MOD_GlcNHglycan	49	52	PF01048	0.426
MOD_GlcNHglycan	5	8	PF01048	0.575
MOD_GlcNHglycan	579	582	PF01048	0.336
MOD_GlcNHglycan	632	635	PF01048	0.274
MOD_GlcNHglycan	857	860	PF01048	0.298
MOD_GlcNHglycan	91	94	PF01048	0.658
MOD_GlcNHglycan	952	955	PF01048	0.671
MOD_GlcNHglycan	979	982	PF01048	0.366
MOD_GlcNHglycan	99	102	PF01048	0.665
MOD_GSK3_1	1006	1013	PF00069	0.467
MOD_GSK3_1	1024	1031	PF00069	0.446
MOD_GSK3_1	1077	1084	PF00069	0.595
MOD_GSK3_1	1096	1103	PF00069	0.595
MOD_GSK3_1	112	119	PF00069	0.746
MOD_GSK3_1	137	144	PF00069	0.640
MOD_GSK3_1	152	159	PF00069	0.688
MOD_GSK3_1	191	198	PF00069	0.667
MOD_GSK3_1	200	207	PF00069	0.789
MOD_GSK3_1	229	236	PF00069	0.717
MOD_GSK3_1	298	305	PF00069	0.673
MOD_GSK3_1	306	313	PF00069	0.702
MOD_GSK3_1	419	426	PF00069	0.631
MOD_GSK3_1	42	49	PF00069	0.463
MOD_GSK3_1	516	523	PF00069	0.337
MOD_GSK3_1	878	885	PF00069	0.280
MOD_GSK3_1	894	901	PF00069	0.294
MOD_GSK3_1	948	955	PF00069	0.561
MOD_N-GLC_1	145	150	PF02516	0.591
MOD_N-GLC_1	164	169	PF02516	0.496
MOD_N-GLC_1	279	284	PF02516	0.460
MOD_N-GLC_1	469	474	PF02516	0.418
MOD_N-GLC_2	884	886	PF02516	0.298
MOD_NEK2_1	1065	1070	PF00069	0.573
MOD_NEK2_1	113	118	PF00069	0.654
MOD_NEK2_1	137	142	PF00069	0.656
MOD_NEK2_1	145	150	PF00069	0.466
MOD_NEK2_1	24	29	PF00069	0.421
MOD_NEK2_1	298	303	PF00069	0.604
MOD_NEK2_1	306	311	PF00069	0.795
MOD_NEK2_1	381	386	PF00069	0.531
MOD_NEK2_1	43	48	PF00069	0.455
MOD_NEK2_1	520	525	PF00069	0.411
MOD_NEK2_1	542	547	PF00069	0.248
MOD_NEK2_1	567	572	PF00069	0.280
MOD_NEK2_1	630	635	PF00069	0.309
MOD_NEK2_1	660	665	PF00069	0.376
MOD_NEK2_1	860	865	PF00069	0.274
MOD_NEK2_1	882	887	PF00069	0.333
MOD_NEK2_2	717	722	PF00069	0.570
MOD_PIKK_1	106	112	PF00454	0.711
MOD_PIKK_1	236	242	PF00454	0.609
MOD_PIKK_1	32	38	PF00454	0.505
MOD_PIKK_1	411	417	PF00454	0.643
MOD_PIKK_1	891	897	PF00454	0.322
MOD_PKA_1	577	583	PF00069	0.279
MOD_PKA_1	905	911	PF00069	0.401
MOD_PKA_2	1010	1016	PF00069	0.350
MOD_PKA_2	106	112	PF00069	0.768
MOD_PKA_2	1086	1092	PF00069	0.545
MOD_PKA_2	1093	1099	PF00069	0.638
MOD_PKA_2	146	152	PF00069	0.560
MOD_PKA_2	184	190	PF00069	0.747
MOD_PKA_2	313	319	PF00069	0.784
MOD_PKA_2	542	548	PF00069	0.274
MOD_PKA_2	577	583	PF00069	0.370
MOD_PKA_2	717	723	PF00069	0.685
MOD_PKA_2	813	819	PF00069	0.389
MOD_PKA_2	905	911	PF00069	0.316
MOD_PKA_2	994	1000	PF00069	0.553
MOD_Plk_1	164	170	PF00069	0.616
MOD_Plk_1	279	285	PF00069	0.451
MOD_Plk_1	43	49	PF00069	0.499
MOD_Plk_1	462	468	PF00069	0.424
MOD_Plk_1	469	475	PF00069	0.385
MOD_Plk_1	550	556	PF00069	0.211
MOD_Plk_2-3	1100	1106	PF00069	0.596
MOD_Plk_2-3	731	737	PF00069	0.638
MOD_Plk_4	1040	1046	PF00069	0.473
MOD_Plk_4	1086	1092	PF00069	0.513
MOD_Plk_4	137	143	PF00069	0.679
MOD_Plk_4	167	173	PF00069	0.771
MOD_Plk_4	462	468	PF00069	0.313
MOD_Plk_4	521	527	PF00069	0.322
MOD_Plk_4	530	536	PF00069	0.240
MOD_Plk_4	569	575	PF00069	0.357
MOD_Plk_4	632	638	PF00069	0.274
MOD_Plk_4	717	723	PF00069	0.685
MOD_Plk_4	849	855	PF00069	0.293
MOD_Plk_4	888	894	PF00069	0.287
MOD_Plk_4	905	911	PF00069	0.196
MOD_ProDKin_1	1006	1012	PF00069	0.475
MOD_ProDKin_1	1050	1056	PF00069	0.497
MOD_ProDKin_1	152	158	PF00069	0.646
MOD_ProDKin_1	206	212	PF00069	0.674
MOD_ProDKin_1	221	227	PF00069	0.636
MOD_ProDKin_1	231	237	PF00069	0.698
MOD_ProDKin_1	376	382	PF00069	0.620
MOD_ProDKin_1	419	425	PF00069	0.646
MOD_ProDKin_1	781	787	PF00069	0.274
MOD_ProDKin_1	952	958	PF00069	0.658
MOD_SUMO_for_1	172	175	PF00179	0.775
MOD_SUMO_rev_2	639	643	PF00179	0.435
TRG_DiLeu_BaEn_1	819	824	PF01217	0.274
TRG_DiLeu_BaEn_3	587	593	PF01217	0.391
TRG_DiLeu_BaLyEn_6	1018	1023	PF01217	0.543
TRG_DiLeu_BaLyEn_6	210	215	PF01217	0.567
TRG_DiLeu_BaLyEn_6	217	222	PF01217	0.513
TRG_DiLeu_BaLyEn_6	248	253	PF01217	0.622
TRG_DiLeu_BaLyEn_6	401	406	PF01217	0.577
TRG_ENDOCYTIC_2	1020	1023	PF00928	0.531
TRG_ENDOCYTIC_2	18	21	PF00928	0.410
TRG_ENDOCYTIC_2	458	461	PF00928	0.356
TRG_ENDOCYTIC_2	571	574	PF00928	0.274
TRG_ENDOCYTIC_2	626	629	PF00928	0.333
TRG_ENDOCYTIC_2	688	691	PF00928	0.420
TRG_ENDOCYTIC_2	752	755	PF00928	0.463
TRG_ENDOCYTIC_2	890	893	PF00928	0.274
TRG_ENDOCYTIC_2	917	920	PF00928	0.274
TRG_ENDOCYTIC_2	971	974	PF00928	0.511
TRG_ER_diArg_1	1058	1061	PF00400	0.428
TRG_ER_diArg_1	1091	1094	PF00400	0.591
TRG_ER_diArg_1	263	265	PF00400	0.477
TRG_ER_diArg_1	290	293	PF00400	0.493
TRG_ER_diArg_1	477	480	PF00400	0.274
TRG_ER_diArg_1	490	492	PF00400	0.274
TRG_Pf-PMV_PEXEL_1	130	134	PF00026	0.570
TRG_Pf-PMV_PEXEL_1	265	269	PF00026	0.657
TRG_Pf-PMV_PEXEL_1	404	408	PF00026	0.607
TRG_Pf-PMV_PEXEL_1	590	594	PF00026	0.336
TRG_Pf-PMV_PEXEL_1	918	923	PF00026	0.282
TRG_Pf-PMV_PEXEL_1	924	928	PF00026	0.356

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM24	Leptomonas seymouri	64%	100%
A0A0S4JHE3	Bodo saltans	38%	100%
A0A1X0P056	Trypanosomatidae	48%	100%
A0A3S5H7K7	Leishmania donovani	93%	100%
A4HH67	Leishmania braziliensis	82%	100%
A4I4B1	Leishmania infantum	92%	100%
C9ZKL6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	100%
E9AM19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q580W5	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	46%	100%