Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ADP8_LEIMA

TriTrypDb:

LmjF.29.0470 , LMJLV39_290010000 , LMJSD75_290010000

Length:

448

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005739	mitochondrion	5	2
GO:0016020	membrane	2	6
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

E9ADP8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ADP8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	234	238	PF00656	0.645
CLV_C14_Caspase3-7	289	293	PF00656	0.719
CLV_C14_Caspase3-7	294	298	PF00656	0.676
CLV_C14_Caspase3-7	401	405	PF00656	0.734
CLV_C14_Caspase3-7	91	95	PF00656	0.648
CLV_NRD_NRD_1	217	219	PF00675	0.465
CLV_NRD_NRD_1	225	227	PF00675	0.504
CLV_PCSK_KEX2_1	101	103	PF00082	0.406
CLV_PCSK_KEX2_1	216	218	PF00082	0.455
CLV_PCSK_KEX2_1	225	227	PF00082	0.505

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7G2	Leptomonas seymouri	60%	100%
A0A3S7X253	Leishmania donovani	94%	100%
A4HH48	Leishmania braziliensis	74%	100%
A4I492	Leishmania infantum	94%	100%
E9AM32	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%

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