Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ADK1_LEIMA

TriTrypDb:

LmjF.28.1995 , LMJLV39_280027800 , LMJSD75_280027400

Length:

109


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	7
GO:0110165	cellular anatomical entity	1	7

E9ADK1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ADK1


Leishmania	From	To	Domain/Motif	Score
DEG_APCC_DBOX_1	73	81	PF00400	0.565
DOC_CKS1_1	84	89	PF01111	0.672
DOC_MAPK_DCC_7	72	82	PF00069	0.654
DOC_MAPK_MEF2A_6	74	82	PF00069	0.685
DOC_PP2B_LxvP_1	29	32	PF13499	0.520
DOC_PP4_FxxP_1	101	104	PF00568	0.534
DOC_PP4_FxxP_1	84	87	PF00568	0.669
DOC_WW_Pin1_4	83	88	PF00397	0.678
LIG_BIR_II_1	1	5	PF00653	0.692
LIG_BRCT_BRCA1_1	97	101	PF00533	0.644
LIG_eIF4E_1	34	40	PF01652	0.323
LIG_LIR_Apic_2	98	104	PF02991	0.664
LIG_LIR_LC3C_4	58	63	PF02991	0.635
LIG_LIR_Nem_3	50	56	PF02991	0.480
LIG_SH2_CRK	34	38	PF00017	0.280
LIG_SH2_PTP2	14	17	PF00017	0.368
LIG_SH2_STAP1	48	52	PF00017	0.346
LIG_SH2_STAT5	14	17	PF00017	0.346
LIG_SH2_STAT5	23	26	PF00017	0.295
LIG_SH3_3	77	83	PF00018	0.755
LIG_SH3_3	91	97	PF00018	0.595
MOD_GlcNHglycan	50	53	PF01048	0.383
MOD_GlcNHglycan	9	12	PF01048	0.391
MOD_GSK3_1	43	50	PF00069	0.365
MOD_GSK3_1	82	89	PF00069	0.598
MOD_NEK2_1	47	52	PF00069	0.348
MOD_NEK2_2	43	48	PF00069	0.346
MOD_Plk_4	43	49	PF00069	0.371
MOD_ProDKin_1	83	89	PF00069	0.605
TRG_DiLeu_BaLyEn_6	51	56	PF01217	0.541
TRG_ENDOCYTIC_2	14	17	PF00928	0.346
TRG_ENDOCYTIC_2	23	26	PF00928	0.295
TRG_ENDOCYTIC_2	34	37	PF00928	0.310
TRG_Pf-PMV_PEXEL_1	54	59	PF00026	0.493


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8F0	Leptomonas seymouri	50%	98%
A0A3Q8IDW2	Leishmania donovani	94%	100%
A4HGQ0	Leishmania braziliensis	71%	100%
A4I3S7	Leishmania infantum	94%	100%
C9ZNQ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
E9B019	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	98%