Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ADJ8_LEIMA

TriTrypDb:

LmjF.28.0785 , LMJLV39_280013500 , LMJSD75_280013500

Length:

190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ADJ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ADJ8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	147	153	PF00089	0.518
CLV_NRD_NRD_1	129	131	PF00675	0.519
CLV_NRD_NRD_1	174	176	PF00675	0.711
CLV_NRD_NRD_1	27	29	PF00675	0.518
CLV_PCSK_KEX2_1	128	130	PF00082	0.456
CLV_PCSK_KEX2_1	176	178	PF00082	0.546
CLV_PCSK_KEX2_1	27	29	PF00082	0.518
CLV_PCSK_KEX2_1	88	90	PF00082	0.585
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.496
CLV_PCSK_PC1ET2_1	88	90	PF00082	0.585
CLV_PCSK_SKI1_1	122	126	PF00082	0.498
CLV_PCSK_SKI1_1	130	134	PF00082	0.442
DEG_APCC_DBOX_1	174	182	PF00400	0.557
DEG_APCC_KENBOX_2	106	110	PF00400	0.512
DOC_CDC14_PxL_1	43	51	PF14671	0.563
DOC_MAPK_MEF2A_6	56	63	PF00069	0.587
DOC_PP1_RVXF_1	120	127	PF00149	0.485
DOC_USP7_MATH_1	98	102	PF00917	0.681
DOC_WW_Pin1_4	54	59	PF00397	0.612
LIG_14-3-3_CanoR_1	128	133	PF00244	0.482
LIG_14-3-3_CanoR_1	167	174	PF00244	0.445
LIG_14-3-3_CanoR_1	185	189	PF00244	0.580
LIG_14-3-3_CanoR_1	89	94	PF00244	0.573
LIG_BIR_II_1	1	5	PF00653	0.613
LIG_BRCT_BRCA1_1	75	79	PF00533	0.532
LIG_Clathr_ClatBox_1	136	140	PF01394	0.540
LIG_DLG_GKlike_1	128	136	PF00625	0.490
LIG_FHA_2	136	142	PF00498	0.532
LIG_FHA_2	18	24	PF00498	0.464
LIG_FHA_2	34	40	PF00498	0.544
LIG_FHA_2	76	82	PF00498	0.573
LIG_FHA_2	8	14	PF00498	0.610
LIG_LIR_Gen_1	131	139	PF02991	0.511
LIG_LIR_Nem_3	131	136	PF02991	0.611
LIG_PDZ_Class_2	185	190	PF00595	0.511
LIG_Pex14_2	133	137	PF04695	0.482
LIG_SH2_STAT5	30	33	PF00017	0.657
LIG_SH3_3	110	116	PF00018	0.540
LIG_SH3_3	41	47	PF00018	0.620
LIG_SUMO_SIM_anti_2	39	44	PF11976	0.552
LIG_TRAF2_1	138	141	PF00917	0.557
MOD_CK1_1	135	141	PF00069	0.605
MOD_CK1_1	170	176	PF00069	0.510
MOD_CK1_1	7	13	PF00069	0.623
MOD_CK1_1	82	88	PF00069	0.556
MOD_CK1_1	91	97	PF00069	0.538
MOD_CK2_1	135	141	PF00069	0.627
MOD_CK2_1	149	155	PF00069	0.503
MOD_CK2_1	166	172	PF00069	0.564
MOD_CK2_1	75	81	PF00069	0.572
MOD_GlcNHglycan	161	164	PF01048	0.552
MOD_GlcNHglycan	80	84	PF01048	0.539
MOD_GlcNHglycan	93	96	PF01048	0.537
MOD_GSK3_1	128	135	PF00069	0.553
MOD_GSK3_1	166	173	PF00069	0.541
MOD_GSK3_1	4	11	PF00069	0.578
MOD_GSK3_1	75	82	PF00069	0.636
MOD_GSK3_1	94	101	PF00069	0.554
MOD_N-GLC_2	6	8	PF02516	0.540
MOD_NEK2_1	132	137	PF00069	0.473
MOD_NEK2_1	17	22	PF00069	0.493
MOD_NEK2_1	4	9	PF00069	0.688
MOD_NEK2_1	79	84	PF00069	0.493
MOD_PIKK_1	8	14	PF00454	0.613
MOD_PKA_1	128	134	PF00069	0.488
MOD_PKA_1	88	94	PF00069	0.576
MOD_PKA_2	128	134	PF00069	0.488
MOD_PKA_2	149	155	PF00069	0.517
MOD_PKA_2	166	172	PF00069	0.546
MOD_PKA_2	184	190	PF00069	0.523
MOD_PKA_2	88	94	PF00069	0.576
MOD_Plk_1	73	79	PF00069	0.615
MOD_Plk_4	132	138	PF00069	0.573
MOD_Plk_4	98	104	PF00069	0.633
MOD_ProDKin_1	54	60	PF00069	0.612
TRG_ER_diArg_1	128	130	PF00400	0.518
TRG_ER_diArg_1	174	177	PF00400	0.706
TRG_NES_CRM1_1	104	118	PF08389	0.536

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7T0	Leptomonas seymouri	43%	95%
A0A3S7X1A2	Leishmania donovani	85%	100%
A4HGB9	Leishmania braziliensis	74%	99%
E9AHH7	Leishmania infantum	85%	100%
E9AZP0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%