Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ADH3_LEIMA

TriTrypDb:

LmjF.27.1945 , LMJLV39_270026600 , LMJSD75_270026600

Length:

259

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ADH3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ADH3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	121	123	PF00675	0.662
CLV_NRD_NRD_1	156	158	PF00675	0.530
CLV_NRD_NRD_1	166	168	PF00675	0.429
CLV_NRD_NRD_1	19	21	PF00675	0.609
CLV_NRD_NRD_1	190	192	PF00675	0.538
CLV_PCSK_FUR_1	119	123	PF00082	0.670
CLV_PCSK_KEX2_1	121	123	PF00082	0.662
CLV_PCSK_KEX2_1	156	158	PF00082	0.530
CLV_PCSK_KEX2_1	166	168	PF00082	0.429
CLV_PCSK_KEX2_1	190	192	PF00082	0.547

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NR64	Trypanosomatidae	29%	100%
A0A3S7X0W4	Leishmania donovani	93%	100%
A4HFW8	Leishmania braziliensis	73%	100%
A4I301	Leishmania infantum	92%	100%
E9AZ97	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%

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