LeishMANIAdb
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CX9C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CX9C domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
E9ADH0_LEIMA
TriTrypDb:
LmjF.27.1910 , LMJLV39_270026300 * , LMJSD75_270026300
Length:
140

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ADH0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ADH0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 28 32 PF00656 0.488
CLV_NRD_NRD_1 53 55 PF00675 0.455
CLV_NRD_NRD_1 57 59 PF00675 0.441
CLV_NRD_NRD_1 66 68 PF00675 0.460
CLV_PCSK_KEX2_1 53 55 PF00082 0.477
CLV_PCSK_KEX2_1 57 59 PF00082 0.453
CLV_PCSK_PC7_1 53 59 PF00082 0.511
CLV_PCSK_SKI1_1 16 20 PF00082 0.397
DOC_CYCLIN_yClb5_NLxxxL_5 5 14 PF00134 0.507
LIG_14-3-3_CanoR_1 129 138 PF00244 0.641
LIG_14-3-3_CanoR_1 21 30 PF00244 0.490
LIG_BIR_II_1 1 5 PF00653 0.590
LIG_BIR_III_1 1 5 PF00653 0.596
LIG_BIR_III_3 1 5 PF00653 0.596
LIG_NRBOX 9 15 PF00104 0.462
LIG_PCNA_yPIPBox_3 11 21 PF02747 0.429
LIG_SH2_SRC 62 65 PF00017 0.450
LIG_SH2_STAT3 121 124 PF00017 0.457
LIG_SH2_STAT3 46 49 PF00017 0.615
LIG_SH2_STAT5 116 119 PF00017 0.389
LIG_SH2_STAT5 121 124 PF00017 0.415
LIG_SH2_STAT5 46 49 PF00017 0.577
LIG_TRAF2_1 61 64 PF00917 0.483
MOD_CK1_1 24 30 PF00069 0.420
MOD_GlcNHglycan 131 134 PF01048 0.656
MOD_GSK3_1 12 19 PF00069 0.412
MOD_GSK3_1 21 28 PF00069 0.432
MOD_NEK2_2 111 116 PF00069 0.557
MOD_PIKK_1 21 27 PF00454 0.534
MOD_PKA_1 74 80 PF00069 0.477
MOD_PKA_2 128 134 PF00069 0.600
MOD_Plk_1 47 53 PF00069 0.511
MOD_Plk_4 111 117 PF00069 0.555
MOD_Plk_4 42 48 PF00069 0.477
MOD_SUMO_rev_2 71 77 PF00179 0.514
TRG_ENDOCYTIC_2 116 119 PF00928 0.389
TRG_ENDOCYTIC_2 62 65 PF00928 0.486
TRG_ER_diArg_1 56 58 PF00400 0.503

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HY93 Leptomonas seymouri 77% 100%
A0A0S4JQ37 Bodo saltans 60% 100%
A0A1X0NRL4 Trypanosomatidae 73% 100%
A0A3S7X0V7 Leishmania donovani 96% 100%
A0A422NJR7 Trypanosoma rangeli 76% 100%
A4HFW5 Leishmania braziliensis 92% 100%
A4I2Z8 Leishmania infantum 96% 100%
C9ZJE8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 63% 100%
E9AZ94 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS