Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Frag1/DRAM/Sfk1 family, putative

Species:

Leishmania major

UniProt:

E9ADF4_LEIMA

TriTrypDb:

LmjF.27.1770 , LMJLV39_270024400 , LMJSD75_270024600

Length:

1499

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Show entries

Cellular components
Term	Name	Level	Count
GO:0005783	endoplasmic reticulum	5	2
GO:0016020	membrane	2	8
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	8

Previous1Next

Expansion

Sequence features

E9ADF4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006497	protein lipidation	5	2
GO:0006505	GPI anchor metabolic process	6	2
GO:0006506	GPI anchor biosynthetic process	6	2
GO:0006629	lipid metabolic process	3	2
GO:0006643	membrane lipid metabolic process	4	2
GO:0006644	phospholipid metabolic process	4	2
GO:0006650	glycerophospholipid metabolic process	5	2
GO:0006661	phosphatidylinositol biosynthetic process	6	2
GO:0006664	glycolipid metabolic process	5	2
GO:0006793	phosphorus metabolic process	3	2

Previous1 2 3 4Next

Could not find GO molecular_function term for this entry.

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1135	1139	PF00656	0.455
CLV_C14_Caspase3-7	1238	1242	PF00656	0.319
CLV_C14_Caspase3-7	949	953	PF00656	0.463
CLV_MEL_PAP_1	184	190	PF00089	0.282
CLV_MEL_PAP_1	455	461	PF00089	0.394
CLV_NRD_NRD_1	1021	1023	PF00675	0.323
CLV_NRD_NRD_1	1039	1041	PF00675	0.237
CLV_NRD_NRD_1	1099	1101	PF00675	0.570
CLV_NRD_NRD_1	1195	1197	PF00675	0.589
CLV_NRD_NRD_1	1258	1260	PF00675	0.536

Previous1 2 3 4 5…55Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IB70	Leptomonas seymouri	64%	100%
A0A1X0P409	Trypanosomatidae	43%	100%
A0A3S7X0U4	Leishmania donovani	92%	100%
A0A422P060	Trypanosoma rangeli	41%	100%
A4I2W7	Leishmania infantum	92%	100%
E9AZ77	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%

Previous1Next