LeishMANIAdb
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Putative diacylglycerol acyltransferase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative diacylglycerol acyltransferase
Gene product:
diacylglycerol acyltransferase, putative
Species:
Leishmania major
UniProt:
E9ADD5_LEIMA
TriTrypDb:
LmjF.27.1560 * , LMJLV39_270021900 * , LMJSD75_270022100 *
Length:
1556

Annotations

LeishMANIAdb annotations

This protein contains a diacylglycerol acyltransferase domain (2TM) fused to an enormous number of TM helices (de novo evolved). The TM domain consists of 4TM bundle units and might have fused secondarily onto the DAGAT domain (already seen in other eukaryotes)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Cellular components
Term Name Level Count
GO:0016020 membrane 2 13
GO:0110165 cellular anatomical entity 1 13

Expansion

Sequence features

E9ADD5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006629 lipid metabolic process 3 2
GO:0006638 neutral lipid metabolic process 4 2
GO:0006639 acylglycerol metabolic process 5 2
GO:0006641 triglyceride metabolic process 6 2
GO:0008152 metabolic process 1 2
GO:0008610 lipid biosynthetic process 4 2
GO:0009058 biosynthetic process 2 2
GO:0009987 cellular process 1 2
GO:0019432 triglyceride biosynthetic process 6 2
GO:0044237 cellular metabolic process 2 2
GO:0044238 primary metabolic process 2 2
GO:0044249 cellular biosynthetic process 3 2
GO:0044255 cellular lipid metabolic process 3 2
GO:0045017 glycerolipid biosynthetic process 4 2
GO:0046460 neutral lipid biosynthetic process 4 2
GO:0046463 acylglycerol biosynthetic process 5 2
GO:0046486 glycerolipid metabolic process 4 2
GO:0071704 organic substance metabolic process 2 2
GO:1901576 organic substance biosynthetic process 3 2
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 12
GO:0004144 diacylglycerol O-acyltransferase activity 7 6
GO:0008374 O-acyltransferase activity 5 12
GO:0016411 acylglycerol O-acyltransferase activity 6 6
GO:0016740 transferase activity 2 12
GO:0016746 acyltransferase activity 3 12
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 811 815 PF00656 0.689
CLV_NRD_NRD_1 1017 1019 PF00675 0.521
CLV_NRD_NRD_1 1070 1072 PF00675 0.426
CLV_NRD_NRD_1 1376 1378 PF00675 0.307
CLV_NRD_NRD_1 1502 1504 PF00675 0.382
CLV_NRD_NRD_1 1519 1521 PF00675 0.228
CLV_NRD_NRD_1 1538 1540 PF00675 0.354
CLV_NRD_NRD_1 213 215 PF00675 0.322
CLV_NRD_NRD_1 268 270 PF00675 0.337
CLV_NRD_NRD_1 729 731 PF00675 0.325
CLV_NRD_NRD_1 781 783 PF00675 0.386
CLV_NRD_NRD_1 827 829 PF00675 0.324
CLV_NRD_NRD_1 962 964 PF00675 0.343
CLV_PCSK_FUR_1 825 829 PF00082 0.397
CLV_PCSK_KEX2_1 1017 1019 PF00082 0.497
CLV_PCSK_KEX2_1 1070 1072 PF00082 0.407
CLV_PCSK_KEX2_1 1376 1378 PF00082 0.341
CLV_PCSK_KEX2_1 1502 1504 PF00082 0.357
CLV_PCSK_KEX2_1 1518 1520 PF00082 0.221
CLV_PCSK_KEX2_1 1540 1542 PF00082 0.440
CLV_PCSK_KEX2_1 1553 1555 PF00082 0.433
CLV_PCSK_KEX2_1 212 214 PF00082 0.314
CLV_PCSK_KEX2_1 268 270 PF00082 0.380
CLV_PCSK_KEX2_1 729 731 PF00082 0.337
CLV_PCSK_KEX2_1 781 783 PF00082 0.409
CLV_PCSK_KEX2_1 825 827 PF00082 0.382
CLV_PCSK_KEX2_1 962 964 PF00082 0.318
CLV_PCSK_PC1ET2_1 1540 1542 PF00082 0.440
CLV_PCSK_PC1ET2_1 1553 1555 PF00082 0.433
CLV_PCSK_PC7_1 209 215 PF00082 0.352
CLV_PCSK_SKI1_1 1207 1211 PF00082 0.212
CLV_PCSK_SKI1_1 1225 1229 PF00082 0.423
CLV_PCSK_SKI1_1 1408 1412 PF00082 0.304
CLV_PCSK_SKI1_1 1513 1517 PF00082 0.245
CLV_PCSK_SKI1_1 172 176 PF00082 0.351
CLV_PCSK_SKI1_1 507 511 PF00082 0.302
CLV_PCSK_SKI1_1 527 531 PF00082 0.381
CLV_PCSK_SKI1_1 719 723 PF00082 0.285
CLV_Separin_Metazoa 1398 1402 PF03568 0.453
DEG_APCC_DBOX_1 1224 1232 PF00400 0.274
DEG_APCC_DBOX_1 1425 1433 PF00400 0.542
DEG_APCC_DBOX_1 1450 1458 PF00400 0.469
DEG_APCC_DBOX_1 1475 1483 PF00400 0.485
DEG_APCC_DBOX_1 267 275 PF00400 0.489
DEG_APCC_DBOX_1 506 514 PF00400 0.466
DEG_Nend_Nbox_1 1 3 PF02207 0.477
DOC_CDC14_PxL_1 1174 1182 PF14671 0.298
DOC_CKS1_1 1111 1116 PF01111 0.356
DOC_CKS1_1 1475 1480 PF01111 0.521
DOC_CKS1_1 417 422 PF01111 0.423
DOC_CKS1_1 991 996 PF01111 0.352
DOC_CYCLIN_RxL_1 266 275 PF00134 0.455
DOC_CYCLIN_yClb5_NLxxxL_5 246 255 PF00134 0.346
DOC_CYCLIN_yClb5_NLxxxL_5 575 584 PF00134 0.346
DOC_CYCLIN_yCln2_LP_2 1175 1181 PF00134 0.343
DOC_CYCLIN_yCln2_LP_2 1457 1463 PF00134 0.451
DOC_CYCLIN_yCln2_LP_2 417 423 PF00134 0.423
DOC_MAPK_DCC_7 1426 1435 PF00069 0.460
DOC_MAPK_DCC_7 441 451 PF00069 0.548
DOC_MAPK_FxFP_2 1459 1462 PF00069 0.452
DOC_MAPK_gen_1 1017 1027 PF00069 0.267
DOC_MAPK_gen_1 1204 1214 PF00069 0.485
DOC_MAPK_gen_1 1448 1456 PF00069 0.492
DOC_MAPK_gen_1 268 276 PF00069 0.553
DOC_MAPK_gen_1 279 289 PF00069 0.515
DOC_MAPK_gen_1 439 448 PF00069 0.463
DOC_MAPK_gen_1 719 728 PF00069 0.492
DOC_MAPK_HePTP_8 1423 1435 PF00069 0.468
DOC_MAPK_MEF2A_6 1204 1212 PF00069 0.485
DOC_MAPK_MEF2A_6 1426 1435 PF00069 0.460
DOC_MAPK_MEF2A_6 1448 1456 PF00069 0.509
DOC_MAPK_MEF2A_6 1468 1475 PF00069 0.341
DOC_MAPK_MEF2A_6 1476 1483 PF00069 0.443
DOC_MAPK_MEF2A_6 282 291 PF00069 0.531
DOC_MAPK_MEF2A_6 441 450 PF00069 0.529
DOC_MAPK_MEF2A_6 583 590 PF00069 0.271
DOC_MAPK_MEF2A_6 855 863 PF00069 0.348
DOC_MAPK_MEF2A_6 990 998 PF00069 0.352
DOC_MAPK_NFAT4_5 1205 1213 PF00069 0.477
DOC_MAPK_NFAT4_5 1468 1476 PF00069 0.488
DOC_PP1_RVXF_1 1043 1049 PF00149 0.472
DOC_PP1_RVXF_1 1271 1278 PF00149 0.494
DOC_PP1_RVXF_1 1453 1460 PF00149 0.427
DOC_PP1_RVXF_1 267 274 PF00149 0.581
DOC_PP1_RVXF_1 831 838 PF00149 0.453
DOC_PP2B_LxvP_1 1032 1035 PF13499 0.341
DOC_PP2B_LxvP_1 1175 1178 PF13499 0.369
DOC_PP2B_LxvP_1 1180 1183 PF13499 0.303
DOC_PP2B_LxvP_1 1357 1360 PF13499 0.384
DOC_PP2B_LxvP_1 1471 1474 PF13499 0.451
DOC_PP2B_LxvP_1 1487 1490 PF13499 0.414
DOC_PP4_FxxP_1 1459 1462 PF00568 0.441
DOC_PP4_FxxP_1 1469 1472 PF00568 0.440
DOC_PP4_FxxP_1 1475 1478 PF00568 0.435
DOC_PP4_FxxP_1 34 37 PF00568 0.558
DOC_PP4_FxxP_1 762 765 PF00568 0.504
DOC_USP7_MATH_1 1026 1030 PF00917 0.456
DOC_USP7_MATH_1 1183 1187 PF00917 0.282
DOC_USP7_MATH_1 1402 1406 PF00917 0.384
DOC_USP7_MATH_1 1422 1426 PF00917 0.551
DOC_USP7_MATH_1 1547 1551 PF00917 0.553
DOC_USP7_MATH_1 180 184 PF00917 0.534
DOC_USP7_MATH_1 476 480 PF00917 0.348
DOC_USP7_MATH_1 665 669 PF00917 0.313
DOC_USP7_MATH_1 721 725 PF00917 0.542
DOC_USP7_MATH_1 737 741 PF00917 0.523
DOC_USP7_MATH_1 758 762 PF00917 0.532
DOC_USP7_MATH_1 789 793 PF00917 0.701
DOC_USP7_MATH_1 79 83 PF00917 0.431
DOC_USP7_MATH_1 931 935 PF00917 0.345
DOC_USP7_UBL2_3 527 531 PF12436 0.550
DOC_USP7_UBL2_3 99 103 PF12436 0.491
DOC_WW_Pin1_4 1062 1067 PF00397 0.687
DOC_WW_Pin1_4 1094 1099 PF00397 0.302
DOC_WW_Pin1_4 1110 1115 PF00397 0.251
DOC_WW_Pin1_4 1474 1479 PF00397 0.459
DOC_WW_Pin1_4 313 318 PF00397 0.290
DOC_WW_Pin1_4 346 351 PF00397 0.601
DOC_WW_Pin1_4 416 421 PF00397 0.343
DOC_WW_Pin1_4 544 549 PF00397 0.666
DOC_WW_Pin1_4 990 995 PF00397 0.346
LIG_14-3-3_CanoR_1 1156 1164 PF00244 0.494
LIG_14-3-3_CanoR_1 1184 1189 PF00244 0.310
LIG_14-3-3_CanoR_1 1276 1284 PF00244 0.488
LIG_14-3-3_CanoR_1 1346 1356 PF00244 0.495
LIG_14-3-3_CanoR_1 1376 1380 PF00244 0.522
LIG_14-3-3_CanoR_1 1385 1390 PF00244 0.482
LIG_14-3-3_CanoR_1 1401 1411 PF00244 0.410
LIG_14-3-3_CanoR_1 1451 1455 PF00244 0.485
LIG_14-3-3_CanoR_1 1476 1482 PF00244 0.468
LIG_14-3-3_CanoR_1 1502 1509 PF00244 0.542
LIG_14-3-3_CanoR_1 172 177 PF00244 0.567
LIG_14-3-3_CanoR_1 19 26 PF00244 0.535
LIG_14-3-3_CanoR_1 268 272 PF00244 0.537
LIG_14-3-3_CanoR_1 279 285 PF00244 0.446
LIG_14-3-3_CanoR_1 439 444 PF00244 0.560
LIG_14-3-3_CanoR_1 497 503 PF00244 0.544
LIG_14-3-3_CanoR_1 709 713 PF00244 0.523
LIG_14-3-3_CanoR_1 752 762 PF00244 0.518
LIG_14-3-3_CanoR_1 788 794 PF00244 0.672
LIG_Actin_WH2_2 1325 1341 PF00022 0.453
LIG_Actin_WH2_2 1352 1370 PF00022 0.484
LIG_APCC_ABBA_1 427 432 PF00400 0.542
LIG_APCC_ABBA_1 540 545 PF00400 0.504
LIG_APCC_ABBA_1 884 889 PF00400 0.496
LIG_APCC_ABBAyCdc20_2 1282 1288 PF00400 0.509
LIG_BRCT_BRCA1_1 1099 1103 PF00533 0.470
LIG_BRCT_BRCA1_1 1185 1189 PF00533 0.322
LIG_BRCT_BRCA1_1 1273 1277 PF00533 0.485
LIG_BRCT_BRCA1_1 148 152 PF00533 0.293
LIG_BRCT_BRCA1_1 172 176 PF00533 0.495
LIG_BRCT_BRCA1_1 260 264 PF00533 0.325
LIG_BRCT_BRCA1_1 269 273 PF00533 0.438
LIG_BRCT_BRCA1_1 353 357 PF00533 0.549
LIG_BRCT_BRCA1_1 376 380 PF00533 0.431
LIG_BRCT_BRCA1_1 500 504 PF00533 0.537
LIG_BRCT_BRCA1_1 636 640 PF00533 0.538
LIG_BRCT_BRCA1_1 842 846 PF00533 0.423
LIG_BRCT_BRCA1_1 859 863 PF00533 0.141
LIG_BRCT_BRCA1_1 947 951 PF00533 0.376
LIG_Clathr_ClatBox_1 1530 1534 PF01394 0.473
LIG_CtBP_PxDLS_1 819 825 PF00389 0.564
LIG_EH1_1 650 658 PF00400 0.395
LIG_EH1_1 688 696 PF00400 0.382
LIG_EH1_1 862 870 PF00400 0.404
LIG_eIF4E_1 1525 1531 PF01652 0.573
LIG_eIF4E_1 69 75 PF01652 0.289
LIG_eIF4E_1 916 922 PF01652 0.376
LIG_FHA_1 1111 1117 PF00498 0.330
LIG_FHA_1 1132 1138 PF00498 0.335
LIG_FHA_1 1152 1158 PF00498 0.342
LIG_FHA_1 1159 1165 PF00498 0.284
LIG_FHA_1 1169 1175 PF00498 0.232
LIG_FHA_1 1185 1191 PF00498 0.253
LIG_FHA_1 1414 1420 PF00498 0.513
LIG_FHA_1 1478 1484 PF00498 0.443
LIG_FHA_1 153 159 PF00498 0.411
LIG_FHA_1 257 263 PF00498 0.436
LIG_FHA_1 284 290 PF00498 0.519
LIG_FHA_1 347 353 PF00498 0.503
LIG_FHA_1 365 371 PF00498 0.414
LIG_FHA_1 39 45 PF00498 0.454
LIG_FHA_1 417 423 PF00498 0.332
LIG_FHA_1 443 449 PF00498 0.529
LIG_FHA_1 484 490 PF00498 0.449
LIG_FHA_1 491 497 PF00498 0.403
LIG_FHA_1 559 565 PF00498 0.573
LIG_FHA_1 576 582 PF00498 0.256
LIG_FHA_1 699 705 PF00498 0.423
LIG_FHA_1 754 760 PF00498 0.539
LIG_FHA_1 765 771 PF00498 0.575
LIG_FHA_1 864 870 PF00498 0.369
LIG_FHA_1 934 940 PF00498 0.294
LIG_FHA_1 945 951 PF00498 0.295
LIG_FHA_1 991 997 PF00498 0.364
LIG_FHA_2 1054 1060 PF00498 0.631
LIG_FHA_2 173 179 PF00498 0.491
LIG_FHA_2 793 799 PF00498 0.632
LIG_FHA_2 924 930 PF00498 0.384
LIG_FHA_2 965 971 PF00498 0.522
LIG_GBD_Chelix_1 460 468 PF00786 0.423
LIG_LIR_Apic_2 761 765 PF02991 0.504
LIG_LIR_Gen_1 1100 1109 PF02991 0.403
LIG_LIR_Gen_1 1274 1285 PF02991 0.542
LIG_LIR_Gen_1 1326 1337 PF02991 0.493
LIG_LIR_Gen_1 1416 1424 PF02991 0.509
LIG_LIR_Gen_1 1506 1517 PF02991 0.485
LIG_LIR_Gen_1 230 240 PF02991 0.435
LIG_LIR_Gen_1 270 280 PF02991 0.587
LIG_LIR_Gen_1 283 291 PF02991 0.559
LIG_LIR_Gen_1 292 302 PF02991 0.351
LIG_LIR_Gen_1 340 350 PF02991 0.566
LIG_LIR_Gen_1 465 474 PF02991 0.433
LIG_LIR_Gen_1 568 577 PF02991 0.445
LIG_LIR_Gen_1 637 646 PF02991 0.444
LIG_LIR_Gen_1 674 683 PF02991 0.400
LIG_LIR_Gen_1 723 732 PF02991 0.583
LIG_LIR_Gen_1 965 976 PF02991 0.569
LIG_LIR_LC3C_4 1480 1483 PF02991 0.509
LIG_LIR_Nem_3 1003 1009 PF02991 0.329
LIG_LIR_Nem_3 1095 1099 PF02991 0.377
LIG_LIR_Nem_3 1100 1106 PF02991 0.380
LIG_LIR_Nem_3 1121 1126 PF02991 0.292
LIG_LIR_Nem_3 1161 1165 PF02991 0.300
LIG_LIR_Nem_3 1274 1280 PF02991 0.495
LIG_LIR_Nem_3 1326 1332 PF02991 0.493
LIG_LIR_Nem_3 135 141 PF02991 0.475
LIG_LIR_Nem_3 1416 1421 PF02991 0.542
LIG_LIR_Nem_3 1506 1512 PF02991 0.468
LIG_LIR_Nem_3 205 210 PF02991 0.496
LIG_LIR_Nem_3 230 235 PF02991 0.397
LIG_LIR_Nem_3 261 267 PF02991 0.348
LIG_LIR_Nem_3 270 276 PF02991 0.497
LIG_LIR_Nem_3 283 287 PF02991 0.467
LIG_LIR_Nem_3 292 297 PF02991 0.351
LIG_LIR_Nem_3 340 346 PF02991 0.560
LIG_LIR_Nem_3 377 382 PF02991 0.373
LIG_LIR_Nem_3 431 437 PF02991 0.490
LIG_LIR_Nem_3 455 459 PF02991 0.388
LIG_LIR_Nem_3 465 469 PF02991 0.365
LIG_LIR_Nem_3 568 574 PF02991 0.414
LIG_LIR_Nem_3 637 643 PF02991 0.447
LIG_LIR_Nem_3 674 678 PF02991 0.355
LIG_LIR_Nem_3 687 692 PF02991 0.345
LIG_LIR_Nem_3 723 728 PF02991 0.576
LIG_LIR_Nem_3 843 849 PF02991 0.413
LIG_LIR_Nem_3 891 896 PF02991 0.466
LIG_LIR_Nem_3 965 971 PF02991 0.573
LIG_LYPXL_yS_3 1525 1528 PF13949 0.492
LIG_MLH1_MIPbox_1 260 264 PF16413 0.226
LIG_MLH1_MIPbox_1 376 380 PF16413 0.444
LIG_NRBOX 1194 1200 PF00104 0.201
LIG_NRBOX 1251 1257 PF00104 0.357
LIG_NRBOX 412 418 PF00104 0.364
LIG_NRBOX 453 459 PF00104 0.346
LIG_NRBOX 576 582 PF00104 0.440
LIG_NRBOX 834 840 PF00104 0.298
LIG_PAM2_1 82 94 PF00658 0.423
LIG_Pex14_1 290 294 PF04695 0.298
LIG_Pex14_2 72 76 PF04695 0.351
LIG_PTB_Apo_2 557 564 PF02174 0.471
LIG_PTB_Phospho_1 557 563 PF10480 0.475
LIG_RPA_C_Fungi 1380 1392 PF08784 0.332
LIG_SH2_CRK 1165 1169 PF00017 0.291
LIG_SH2_CRK 1215 1219 PF00017 0.318
LIG_SH2_CRK 138 142 PF00017 0.446
LIG_SH2_CRK 882 886 PF00017 0.297
LIG_SH2_CRK 992 996 PF00017 0.428
LIG_SH2_GRB2like 1292 1295 PF00017 0.343
LIG_SH2_GRB2like 65 68 PF00017 0.408
LIG_SH2_NCK_1 1215 1219 PF00017 0.346
LIG_SH2_NCK_1 710 714 PF00017 0.415
LIG_SH2_SRC 1123 1126 PF00017 0.475
LIG_SH2_STAP1 343 347 PF00017 0.359
LIG_SH2_STAP1 651 655 PF00017 0.283
LIG_SH2_STAP1 710 714 PF00017 0.315
LIG_SH2_STAT3 65 68 PF00017 0.348
LIG_SH2_STAT5 1006 1009 PF00017 0.333
LIG_SH2_STAT5 1107 1110 PF00017 0.319
LIG_SH2_STAT5 1112 1115 PF00017 0.303
LIG_SH2_STAT5 1123 1126 PF00017 0.276
LIG_SH2_STAT5 1142 1145 PF00017 0.320
LIG_SH2_STAT5 1165 1168 PF00017 0.393
LIG_SH2_STAT5 1220 1223 PF00017 0.297
LIG_SH2_STAT5 1258 1261 PF00017 0.314
LIG_SH2_STAT5 1284 1287 PF00017 0.276
LIG_SH2_STAT5 1292 1295 PF00017 0.266
LIG_SH2_STAT5 1313 1316 PF00017 0.299
LIG_SH2_STAT5 1347 1350 PF00017 0.343
LIG_SH2_STAT5 1508 1511 PF00017 0.283
LIG_SH2_STAT5 210 213 PF00017 0.362
LIG_SH2_STAT5 296 299 PF00017 0.382
LIG_SH2_STAT5 381 384 PF00017 0.326
LIG_SH2_STAT5 423 426 PF00017 0.350
LIG_SH2_STAT5 456 459 PF00017 0.395
LIG_SH2_STAT5 563 566 PF00017 0.427
LIG_SH2_STAT5 573 576 PF00017 0.393
LIG_SH2_STAT5 65 68 PF00017 0.408
LIG_SH2_STAT5 710 713 PF00017 0.441
LIG_SH2_STAT5 93 96 PF00017 0.381
LIG_SH2_STAT5 992 995 PF00017 0.294
LIG_SH3_2 895 900 PF14604 0.432
LIG_SH3_3 1143 1149 PF00018 0.382
LIG_SH3_3 1228 1234 PF00018 0.279
LIG_SH3_3 1296 1302 PF00018 0.355
LIG_SH3_3 1425 1431 PF00018 0.283
LIG_SH3_3 1459 1465 PF00018 0.339
LIG_SH3_3 1479 1485 PF00018 0.187
LIG_SH3_3 347 353 PF00018 0.368
LIG_SH3_3 511 517 PF00018 0.538
LIG_SH3_3 594 600 PF00018 0.371
LIG_SH3_3 67 73 PF00018 0.287
LIG_SH3_3 889 895 PF00018 0.454
LIG_SH3_3 988 994 PF00018 0.346
LIG_SH3_4 527 534 PF00018 0.379
LIG_SH3_CIN85_PxpxPR_1 546 551 PF14604 0.334
LIG_SUMO_SIM_anti_2 1087 1093 PF11976 0.349
LIG_SUMO_SIM_anti_2 1097 1103 PF11976 0.338
LIG_SUMO_SIM_anti_2 1131 1138 PF11976 0.301
LIG_SUMO_SIM_anti_2 1171 1178 PF11976 0.250
LIG_SUMO_SIM_anti_2 1388 1393 PF11976 0.318
LIG_SUMO_SIM_anti_2 1477 1483 PF11976 0.318
LIG_SUMO_SIM_anti_2 1529 1537 PF11976 0.542
LIG_SUMO_SIM_anti_2 222 228 PF11976 0.321
LIG_SUMO_SIM_anti_2 303 308 PF11976 0.272
LIG_SUMO_SIM_anti_2 316 322 PF11976 0.469
LIG_SUMO_SIM_anti_2 330 336 PF11976 0.283
LIG_SUMO_SIM_anti_2 40 46 PF11976 0.389
LIG_SUMO_SIM_anti_2 537 545 PF11976 0.289
LIG_SUMO_SIM_par_1 1023 1029 PF11976 0.316
LIG_SUMO_SIM_par_1 1037 1042 PF11976 0.290
LIG_SUMO_SIM_par_1 1133 1138 PF11976 0.343
LIG_SUMO_SIM_par_1 13 18 PF11976 0.322
LIG_SUMO_SIM_par_1 1388 1393 PF11976 0.373
LIG_SUMO_SIM_par_1 1405 1413 PF11976 0.376
LIG_SUMO_SIM_par_1 1485 1491 PF11976 0.316
LIG_SUMO_SIM_par_1 1529 1537 PF11976 0.542
LIG_SUMO_SIM_par_1 164 170 PF11976 0.365
LIG_SUMO_SIM_par_1 361 367 PF11976 0.383
LIG_SUMO_SIM_par_1 40 46 PF11976 0.370
LIG_SUMO_SIM_par_1 402 408 PF11976 0.391
LIG_SUMO_SIM_par_1 537 545 PF11976 0.343
LIG_SUMO_SIM_par_1 584 589 PF11976 0.321
LIG_SUMO_SIM_par_1 656 662 PF11976 0.429
LIG_SUMO_SIM_par_1 920 927 PF11976 0.343
LIG_SUMO_SIM_par_1 942 948 PF11976 0.402
LIG_SUMO_SIM_par_1 974 981 PF11976 0.423
LIG_TRAF2_1 740 743 PF00917 0.449
LIG_TRAF2_1 797 800 PF00917 0.501
LIG_TYR_ITIM 1256 1261 PF00017 0.449
LIG_UBA3_1 1038 1045 PF00899 0.367
LIG_UBA3_1 770 775 PF00899 0.496
LIG_WRC_WIRS_1 1093 1098 PF05994 0.274
LIG_WRC_WIRS_1 1314 1319 PF05994 0.343
LIG_WRC_WIRS_1 171 176 PF05994 0.425
LIG_WRC_WIRS_1 273 278 PF05994 0.382
LIG_WRC_WIRS_1 463 468 PF05994 0.346
LIG_WRC_WIRS_1 759 764 PF05994 0.371
LIG_WRC_WIRS_1 979 984 PF05994 0.332
MOD_CDK_SPK_2 1110 1115 PF00069 0.347
MOD_CDK_SPxxK_3 544 551 PF00069 0.399
MOD_CK1_1 1013 1019 PF00069 0.385
MOD_CK1_1 1062 1068 PF00069 0.584
MOD_CK1_1 1271 1277 PF00069 0.298
MOD_CK1_1 1375 1381 PF00069 0.297
MOD_CK1_1 170 176 PF00069 0.363
MOD_CK1_1 191 197 PF00069 0.510
MOD_CK1_1 230 236 PF00069 0.407
MOD_CK1_1 327 333 PF00069 0.375
MOD_CK1_1 40 46 PF00069 0.325
MOD_CK1_1 442 448 PF00069 0.362
MOD_CK1_1 485 491 PF00069 0.431
MOD_CK1_1 500 506 PF00069 0.463
MOD_CK1_1 519 525 PF00069 0.337
MOD_CK1_1 792 798 PF00069 0.710
MOD_CK1_1 809 815 PF00069 0.391
MOD_CK1_1 927 933 PF00069 0.413
MOD_CK1_1 945 951 PF00069 0.170
MOD_CK2_1 1053 1059 PF00069 0.493
MOD_CK2_1 216 222 PF00069 0.407
MOD_CK2_1 352 358 PF00069 0.365
MOD_CK2_1 721 727 PF00069 0.393
MOD_CK2_1 737 743 PF00069 0.401
MOD_CK2_1 794 800 PF00069 0.724
MOD_CK2_1 923 929 PF00069 0.380
MOD_CK2_1 964 970 PF00069 0.353
MOD_Cter_Amidation 524 527 PF01082 0.655
MOD_DYRK1A_RPxSP_1 990 994 PF00069 0.346
MOD_GlcNHglycan 1011 1016 PF01048 0.443
MOD_GlcNHglycan 1171 1174 PF01048 0.365
MOD_GlcNHglycan 1262 1265 PF01048 0.396
MOD_GlcNHglycan 191 194 PF01048 0.480
MOD_GlcNHglycan 195 198 PF01048 0.435
MOD_GlcNHglycan 204 207 PF01048 0.380
MOD_GlcNHglycan 218 221 PF01048 0.241
MOD_GlcNHglycan 229 232 PF01048 0.395
MOD_GlcNHglycan 424 427 PF01048 0.368
MOD_GlcNHglycan 472 475 PF01048 0.407
MOD_GlcNHglycan 621 624 PF01048 0.311
MOD_GlcNHglycan 636 639 PF01048 0.307
MOD_GlcNHglycan 817 820 PF01048 0.558
MOD_GlcNHglycan 842 845 PF01048 0.326
MOD_GlcNHglycan 929 932 PF01048 0.406
MOD_GlcNHglycan 933 936 PF01048 0.413
MOD_GlcNHglycan 982 985 PF01048 0.423
MOD_GSK3_1 1062 1069 PF00069 0.549
MOD_GSK3_1 1131 1138 PF00069 0.399
MOD_GSK3_1 1151 1158 PF00069 0.143
MOD_GSK3_1 123 130 PF00069 0.355
MOD_GSK3_1 1271 1278 PF00069 0.376
MOD_GSK3_1 1347 1354 PF00069 0.343
MOD_GSK3_1 1375 1382 PF00069 0.325
MOD_GSK3_1 142 149 PF00069 0.402
MOD_GSK3_1 15 22 PF00069 0.490
MOD_GSK3_1 180 187 PF00069 0.435
MOD_GSK3_1 189 196 PF00069 0.348
MOD_GSK3_1 412 419 PF00069 0.415
MOD_GSK3_1 515 522 PF00069 0.537
MOD_GSK3_1 55 62 PF00069 0.434
MOD_GSK3_1 632 639 PF00069 0.443
MOD_GSK3_1 659 666 PF00069 0.363
MOD_GSK3_1 780 787 PF00069 0.538
MOD_GSK3_1 806 813 PF00069 0.676
MOD_GSK3_1 920 927 PF00069 0.336
MOD_N-GLC_1 146 151 PF02516 0.305
MOD_N-GLC_1 374 379 PF02516 0.334
MOD_N-GLC_1 439 444 PF02516 0.366
MOD_N-GLC_1 806 811 PF02516 0.742
MOD_NEK2_1 1 6 PF00069 0.431
MOD_NEK2_1 1028 1033 PF00069 0.307
MOD_NEK2_1 1041 1046 PF00069 0.273
MOD_NEK2_1 1092 1097 PF00069 0.264
MOD_NEK2_1 1128 1133 PF00069 0.311
MOD_NEK2_1 1135 1140 PF00069 0.286
MOD_NEK2_1 1151 1156 PF00069 0.272
MOD_NEK2_1 1169 1174 PF00069 0.244
MOD_NEK2_1 123 128 PF00069 0.390
MOD_NEK2_1 132 137 PF00069 0.370
MOD_NEK2_1 1328 1333 PF00069 0.354
MOD_NEK2_1 1372 1377 PF00069 0.289
MOD_NEK2_1 1390 1395 PF00069 0.302
MOD_NEK2_1 152 157 PF00069 0.375
MOD_NEK2_1 167 172 PF00069 0.210
MOD_NEK2_1 225 230 PF00069 0.322
MOD_NEK2_1 242 247 PF00069 0.357
MOD_NEK2_1 251 256 PF00069 0.334
MOD_NEK2_1 289 294 PF00069 0.335
MOD_NEK2_1 337 342 PF00069 0.310
MOD_NEK2_1 374 379 PF00069 0.393
MOD_NEK2_1 393 398 PF00069 0.231
MOD_NEK2_1 468 473 PF00069 0.345
MOD_NEK2_1 490 495 PF00069 0.367
MOD_NEK2_1 498 503 PF00069 0.386
MOD_NEK2_1 558 563 PF00069 0.407
MOD_NEK2_1 569 574 PF00069 0.232
MOD_NEK2_1 575 580 PF00069 0.201
MOD_NEK2_1 634 639 PF00069 0.312
MOD_NEK2_1 8 13 PF00069 0.410
MOD_NEK2_1 857 862 PF00069 0.350
MOD_NEK2_1 863 868 PF00069 0.308
MOD_NEK2_1 869 874 PF00069 0.275
MOD_NEK2_1 920 925 PF00069 0.303
MOD_NEK2_1 944 949 PF00069 0.430
MOD_NEK2_1 951 956 PF00069 0.367
MOD_NEK2_1 980 985 PF00069 0.325
MOD_NEK2_2 1313 1318 PF00069 0.343
MOD_NEK2_2 1508 1513 PF00069 0.376
MOD_NEK2_2 258 263 PF00069 0.379
MOD_NEK2_2 272 277 PF00069 0.357
MOD_OFUCOSY 122 127 PF10250 0.346
MOD_PIKK_1 1 7 PF00454 0.485
MOD_PIKK_1 1000 1006 PF00454 0.476
MOD_PIKK_1 1107 1113 PF00454 0.323
MOD_PIKK_1 1268 1274 PF00454 0.483
MOD_PIKK_1 1308 1314 PF00454 0.423
MOD_PIKK_1 1410 1416 PF00454 0.391
MOD_PIKK_1 225 231 PF00454 0.323
MOD_PIKK_1 405 411 PF00454 0.430
MOD_PIKK_1 900 906 PF00454 0.471
MOD_PIKK_1 945 951 PF00454 0.318
MOD_PK_1 1385 1391 PF00069 0.423
MOD_PK_1 439 445 PF00069 0.316
MOD_PKA_1 1502 1508 PF00069 0.346
MOD_PKA_2 1016 1022 PF00069 0.278
MOD_PKA_2 1155 1161 PF00069 0.402
MOD_PKA_2 1183 1189 PF00069 0.378
MOD_PKA_2 1275 1281 PF00069 0.346
MOD_PKA_2 1375 1381 PF00069 0.376
MOD_PKA_2 1450 1456 PF00069 0.343
MOD_PKA_2 1502 1508 PF00069 0.346
MOD_PKA_2 267 273 PF00069 0.427
MOD_PKA_2 708 714 PF00069 0.365
MOD_PKA_2 780 786 PF00069 0.596
MOD_PKA_2 809 815 PF00069 0.679
MOD_Plk_1 1308 1314 PF00069 0.298
MOD_Plk_1 1379 1385 PF00069 0.393
MOD_Plk_1 374 380 PF00069 0.454
MOD_Plk_1 439 445 PF00069 0.364
MOD_Plk_1 586 592 PF00069 0.315
MOD_Plk_1 820 826 PF00069 0.536
MOD_Plk_4 1034 1040 PF00069 0.380
MOD_Plk_4 1097 1103 PF00069 0.275
MOD_Plk_4 1131 1137 PF00069 0.332
MOD_Plk_4 1158 1164 PF00069 0.349
MOD_Plk_4 1184 1190 PF00069 0.381
MOD_Plk_4 128 134 PF00069 0.375
MOD_Plk_4 1351 1357 PF00069 0.346
MOD_Plk_4 1385 1391 PF00069 0.345
MOD_Plk_4 1477 1483 PF00069 0.299
MOD_Plk_4 242 248 PF00069 0.290
MOD_Plk_4 258 264 PF00069 0.332
MOD_Plk_4 283 289 PF00069 0.350
MOD_Plk_4 300 306 PF00069 0.301
MOD_Plk_4 316 322 PF00069 0.311
MOD_Plk_4 324 330 PF00069 0.288
MOD_Plk_4 352 358 PF00069 0.336
MOD_Plk_4 374 380 PF00069 0.368
MOD_Plk_4 40 46 PF00069 0.384
MOD_Plk_4 412 418 PF00069 0.341
MOD_Plk_4 452 458 PF00069 0.372
MOD_Plk_4 485 491 PF00069 0.365
MOD_Plk_4 535 541 PF00069 0.489
MOD_Plk_4 636 642 PF00069 0.315
MOD_Plk_4 659 665 PF00069 0.296
MOD_Plk_4 684 690 PF00069 0.358
MOD_Plk_4 721 727 PF00069 0.465
MOD_Plk_4 766 772 PF00069 0.490
MOD_Plk_4 888 894 PF00069 0.312
MOD_Plk_4 920 926 PF00069 0.417
MOD_Plk_4 964 970 PF00069 0.352
MOD_ProDKin_1 1062 1068 PF00069 0.625
MOD_ProDKin_1 1094 1100 PF00069 0.302
MOD_ProDKin_1 1110 1116 PF00069 0.295
MOD_ProDKin_1 1474 1480 PF00069 0.306
MOD_ProDKin_1 313 319 PF00069 0.349
MOD_ProDKin_1 346 352 PF00069 0.504
MOD_ProDKin_1 416 422 PF00069 0.343
MOD_ProDKin_1 544 550 PF00069 0.600
MOD_ProDKin_1 990 996 PF00069 0.346
MOD_SUMO_rev_2 738 746 PF00179 0.531
TRG_AP2beta_CARGO_1 431 441 PF09066 0.369
TRG_DiLeu_BaEn_1 1407 1412 PF01217 0.274
TRG_DiLeu_BaEn_1 244 249 PF01217 0.226
TRG_DiLeu_BaEn_1 674 679 PF01217 0.380
TRG_DiLeu_BaEn_2 726 732 PF01217 0.398
TRG_DiLeu_BaEn_2 888 894 PF01217 0.289
TRG_DiLeu_BaLyEn_6 1357 1362 PF01217 0.346
TRG_DiLeu_BaLyEn_6 1428 1433 PF01217 0.376
TRG_DiLeu_BaLyEn_6 580 585 PF01217 0.406
TRG_DiLeu_BaLyEn_6 600 605 PF01217 0.399
TRG_ENDOCYTIC_2 108 111 PF00928 0.286
TRG_ENDOCYTIC_2 1123 1126 PF00928 0.357
TRG_ENDOCYTIC_2 1215 1218 PF00928 0.299
TRG_ENDOCYTIC_2 1258 1261 PF00928 0.365
TRG_ENDOCYTIC_2 1292 1295 PF00928 0.304
TRG_ENDOCYTIC_2 138 141 PF00928 0.380
TRG_ENDOCYTIC_2 1525 1528 PF00928 0.352
TRG_ENDOCYTIC_2 343 346 PF00928 0.308
TRG_ENDOCYTIC_2 69 72 PF00928 0.427
TRG_ENDOCYTIC_2 882 885 PF00928 0.294
TRG_ENDOCYTIC_2 992 995 PF00928 0.382
TRG_ER_diArg_1 1017 1020 PF00400 0.371
TRG_ER_diArg_1 1501 1503 PF00400 0.420
TRG_ER_diArg_1 1517 1520 PF00400 0.273
TRG_ER_diArg_1 211 214 PF00400 0.402
TRG_ER_diArg_1 267 269 PF00400 0.476
TRG_ER_diArg_1 276 279 PF00400 0.417
TRG_ER_diArg_1 550 553 PF00400 0.565
TRG_ER_diArg_1 728 730 PF00400 0.415
TRG_ER_diArg_1 824 827 PF00400 0.539
TRG_NES_CRM1_1 693 707 PF08389 0.343
TRG_NLS_MonoCore_2 1538 1543 PF00514 0.414
TRG_NLS_MonoExtN_4 1539 1544 PF00514 0.565
TRG_Pf-PMV_PEXEL_1 1296 1300 PF00026 0.320
TRG_Pf-PMV_PEXEL_1 583 587 PF00026 0.425

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IK34 Leptomonas seymouri 58% 94%
A0A0S4JP25 Bodo saltans 22% 98%
A0A0S4JP41 Bodo saltans 27% 100%
A0A1X0P4J0 Trypanosomatidae 34% 100%
A0A3S7X0R5 Leishmania donovani 93% 100%
A0A422N9P8 Trypanosoma rangeli 33% 100%
A4HFT3 Leishmania braziliensis 76% 96%
A4I2U8 Leishmania infantum 93% 97%
D0A623 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 23% 100%
E9AZ60 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 97%
V5B0Y1 Trypanosoma cruzi 32% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS