LeishMANIAdb
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PEROXIDASE_4 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
PEROXIDASE_4 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
E9ADB0_LEIMA
TriTrypDb:
LmjF.27.1295
Length:
142

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ADB0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ADB0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_MEL_PAP_1 131 137 PF00089 0.753
CLV_PCSK_KEX2_1 100 102 PF00082 0.717
CLV_PCSK_PC1ET2_1 100 102 PF00082 0.717
DEG_APCC_DBOX_1 27 35 PF00400 0.414
DOC_CDC14_PxL_1 108 116 PF14671 0.520
DOC_MAPK_gen_1 118 127 PF00069 0.593
DOC_MAPK_MEF2A_6 71 78 PF00069 0.638
DOC_USP7_MATH_1 110 114 PF00917 0.497
DOC_WW_Pin1_4 51 56 PF00397 0.613
LIG_14-3-3_CanoR_1 101 108 PF00244 0.524
LIG_14-3-3_CanoR_1 120 127 PF00244 0.662
LIG_14-3-3_CanoR_1 19 29 PF00244 0.434
LIG_BRCT_BRCA1_1 118 122 PF00533 0.764
LIG_deltaCOP1_diTrp_1 115 122 PF00928 0.753
LIG_FHA_2 57 63 PF00498 0.676
LIG_FHA_2 87 93 PF00498 0.675
LIG_LIR_Gen_1 119 127 PF02991 0.549
LIG_LIR_Gen_1 39 49 PF02991 0.412
LIG_LIR_Nem_3 119 125 PF02991 0.551
LIG_SH2_STAP1 83 87 PF00017 0.622
LIG_SH2_STAT5 33 36 PF00017 0.620
LIG_SH3_3 26 32 PF00018 0.633
MOD_CK1_1 123 129 PF00069 0.759
MOD_CK1_1 14 20 PF00069 0.635
MOD_CK1_1 23 29 PF00069 0.634
MOD_CK1_1 56 62 PF00069 0.511
MOD_CK2_1 86 92 PF00069 0.539
MOD_GlcNHglycan 102 105 PF01048 0.708
MOD_GlcNHglycan 122 125 PF01048 0.451
MOD_GlcNHglycan 128 131 PF01048 0.662
MOD_GlcNHglycan 19 22 PF01048 0.427
MOD_GlcNHglycan 55 58 PF01048 0.556
MOD_GlcNHglycan 9 12 PF01048 0.622
MOD_GSK3_1 116 123 PF00069 0.757
MOD_GSK3_1 126 133 PF00069 0.596
MOD_GSK3_1 49 56 PF00069 0.393
MOD_GSK3_1 7 14 PF00069 0.474
MOD_GSK3_1 96 103 PF00069 0.495
MOD_NEK2_1 12 17 PF00069 0.516
MOD_NEK2_1 49 54 PF00069 0.389
MOD_PIKK_1 20 26 PF00454 0.432
MOD_PKA_1 100 106 PF00069 0.717
MOD_PKA_2 100 106 PF00069 0.717
MOD_PKA_2 133 139 PF00069 0.753
MOD_PKA_2 70 76 PF00069 0.652
MOD_PKB_1 118 126 PF00069 0.761
MOD_ProDKin_1 51 57 PF00069 0.613
MOD_SUMO_rev_2 90 99 PF00179 0.485
TRG_DiLeu_BaEn_2 62 68 PF01217 0.728
TRG_ER_diArg_1 117 120 PF00400 0.756

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IPX1 Leishmania donovani 87% 87%
A4I2T2 Leishmania infantum 87% 87%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS