Putative 2-oxoglutarate dehydrogenase subunit

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

2-oxoglutarate dehydrogenase subunit, putative

Species:

Leishmania major

UniProt:

E9AD65_LEIMA

TriTrypDb:

LmjF.27.0880 , LMJLV39_270014500 , LMJSD75_270014500

Length:

1006

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 45

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 24

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 2, no: 15
NetGPI	no	yes: 0, no: 17

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	3
GO:0005739	mitochondrion	5	3
GO:0005929	cilium	4	2
GO:0032991	protein-containing complex	1	3
GO:0042995	cell projection	2	2
GO:0043226	organelle	2	3
GO:0043227	membrane-bounded organelle	3	3
GO:0043229	intracellular organelle	3	3
GO:0043231	intracellular membrane-bounded organelle	4	3
GO:0045239	tricarboxylic acid cycle enzyme complex	3	3
GO:0045240	dihydrolipoyl dehydrogenase complex	4	3
GO:0045252	oxoglutarate dehydrogenase complex	4	3
GO:0110165	cellular anatomical entity	1	3
GO:0120025	plasma membrane bounded cell projection	3	2
GO:1902494	catalytic complex	2	3
GO:1990204	oxidoreductase complex	3	3
GO:1990234	transferase complex	3	3
GO:0005815	microtubule organizing center	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0036064	ciliary basal body	3	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

E9AD65

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AD65

Function

Biological processes
Term	Name	Level	Count
GO:0006099	tricarboxylic acid cycle	3	18
GO:0008152	metabolic process	1	18
GO:0044238	primary metabolic process	2	18

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	18
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	5	18
GO:0005488	binding	1	18
GO:0016491	oxidoreductase activity	2	18
GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	4	18
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3	18
GO:0019842	vitamin binding	3	18
GO:0030976	thiamine pyrophosphate binding	3	18
GO:0036094	small molecule binding	2	18
GO:0043167	ion binding	2	18
GO:0043168	anion binding	3	18
GO:0043169	cation binding	3	18
GO:0050997	quaternary ammonium group binding	2	18
GO:0097159	organic cyclic compound binding	2	18
GO:1901363	heterocyclic compound binding	2	18
GO:1901681	sulfur compound binding	2	18

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	19	23	PF00656	0.582
CLV_C14_Caspase3-7	208	212	PF00656	0.439
CLV_C14_Caspase3-7	448	452	PF00656	0.557
CLV_C14_Caspase3-7	626	630	PF00656	0.497
CLV_NRD_NRD_1	182	184	PF00675	0.457
CLV_NRD_NRD_1	221	223	PF00675	0.492
CLV_NRD_NRD_1	26	28	PF00675	0.623
CLV_NRD_NRD_1	292	294	PF00675	0.235
CLV_NRD_NRD_1	3	5	PF00675	0.604
CLV_NRD_NRD_1	324	326	PF00675	0.280
CLV_NRD_NRD_1	479	481	PF00675	0.298
CLV_NRD_NRD_1	620	622	PF00675	0.461
CLV_NRD_NRD_1	805	807	PF00675	0.372
CLV_NRD_NRD_1	825	827	PF00675	0.289
CLV_NRD_NRD_1	876	878	PF00675	0.288
CLV_PCSK_FUR_1	803	807	PF00082	0.357
CLV_PCSK_KEX2_1	182	184	PF00082	0.419
CLV_PCSK_KEX2_1	221	223	PF00082	0.480
CLV_PCSK_KEX2_1	3	5	PF00082	0.604
CLV_PCSK_KEX2_1	324	326	PF00082	0.347
CLV_PCSK_KEX2_1	479	481	PF00082	0.304
CLV_PCSK_KEX2_1	805	807	PF00082	0.343
CLV_PCSK_KEX2_1	825	827	PF00082	0.289
CLV_PCSK_PC1ET2_1	324	326	PF00082	0.347
CLV_PCSK_SKI1_1	241	245	PF00082	0.365
CLV_PCSK_SKI1_1	297	301	PF00082	0.308
CLV_PCSK_SKI1_1	3	7	PF00082	0.582
CLV_PCSK_SKI1_1	455	459	PF00082	0.294
CLV_PCSK_SKI1_1	717	721	PF00082	0.357
CLV_PCSK_SKI1_1	878	882	PF00082	0.260
DEG_APCC_DBOX_1	2	10	PF00400	0.612
DEG_APCC_DBOX_1	281	289	PF00400	0.498
DEG_APCC_DBOX_1	292	300	PF00400	0.498
DOC_CKS1_1	814	819	PF01111	0.489
DOC_CYCLIN_RxL_1	230	244	PF00134	0.419
DOC_CYCLIN_RxL_1	773	784	PF00134	0.447
DOC_CYCLIN_RxL_1	959	972	PF00134	0.448
DOC_CYCLIN_yCln2_LP_2	256	262	PF00134	0.480
DOC_MAPK_gen_1	324	330	PF00069	0.541
DOC_MAPK_gen_1	94	102	PF00069	0.420
DOC_MAPK_MEF2A_6	830	839	PF00069	0.495
DOC_PIKK_1	39	47	PF02985	0.596
DOC_PP1_RVXF_1	875	882	PF00149	0.456
DOC_PP1_RVXF_1	99	105	PF00149	0.450
DOC_PP2B_LxvP_1	756	759	PF13499	0.467
DOC_PP2B_LxvP_1	845	848	PF13499	0.562
DOC_PP4_FxxP_1	491	494	PF00568	0.449
DOC_PP4_FxxP_1	82	85	PF00568	0.552
DOC_PP4_FxxP_1	832	835	PF00568	0.522
DOC_USP7_MATH_1	16	20	PF00917	0.683
DOC_USP7_MATH_1	342	346	PF00917	0.467
DOC_USP7_MATH_1	422	426	PF00917	0.498
DOC_USP7_MATH_1	68	72	PF00917	0.541
DOC_USP7_MATH_1	767	771	PF00917	0.489
DOC_USP7_MATH_1	983	987	PF00917	0.501
DOC_USP7_UBL2_3	241	245	PF12436	0.605
DOC_USP7_UBL2_3	512	516	PF12436	0.480
DOC_USP7_UBL2_3	526	530	PF12436	0.474
DOC_USP7_UBL2_3	605	609	PF12436	0.547
DOC_USP7_UBL2_3	674	678	PF12436	0.557
DOC_WW_Pin1_4	683	688	PF00397	0.534
DOC_WW_Pin1_4	73	78	PF00397	0.641
DOC_WW_Pin1_4	813	818	PF00397	0.489
DOC_WW_Pin1_4	898	903	PF00397	0.546
DOC_WW_Pin1_4	981	986	PF00397	0.464
LIG_14-3-3_CanoR_1	101	105	PF00244	0.487
LIG_14-3-3_CanoR_1	13	20	PF00244	0.611
LIG_14-3-3_CanoR_1	293	297	PF00244	0.435
LIG_14-3-3_CanoR_1	325	331	PF00244	0.448
LIG_14-3-3_CanoR_1	359	365	PF00244	0.491
LIG_14-3-3_CanoR_1	426	434	PF00244	0.541
LIG_14-3-3_CanoR_1	542	550	PF00244	0.553
LIG_14-3-3_CanoR_1	660	670	PF00244	0.456
LIG_14-3-3_CanoR_1	934	943	PF00244	0.545
LIG_14-3-3_CanoR_1	959	964	PF00244	0.518
LIG_Actin_WH2_1	284	299	PF00022	0.557
LIG_Actin_WH2_2	281	299	PF00022	0.557
LIG_Actin_WH2_2	581	596	PF00022	0.472
LIG_Actin_WH2_2	956	972	PF00022	0.394
LIG_ActinCP_TwfCPI_2	82	89	PF01115	0.644
LIG_APCC_ABBA_1	376	381	PF00400	0.498
LIG_BRCT_BRCA1_1	194	198	PF00533	0.434
LIG_Clathr_ClatBox_1	910	914	PF01394	0.509
LIG_EH1_1	41	49	PF00400	0.467
LIG_FHA_1	313	319	PF00498	0.516
LIG_FHA_1	363	369	PF00498	0.500
LIG_FHA_1	405	411	PF00498	0.484
LIG_FHA_1	509	515	PF00498	0.576
LIG_FHA_1	588	594	PF00498	0.517
LIG_FHA_1	714	720	PF00498	0.589
LIG_FHA_1	899	905	PF00498	0.549
LIG_FHA_1	936	942	PF00498	0.522
LIG_FHA_2	143	149	PF00498	0.375
LIG_FHA_2	264	270	PF00498	0.494
LIG_FHA_2	519	525	PF00498	0.517
LIG_FHA_2	561	567	PF00498	0.633
LIG_FHA_2	584	590	PF00498	0.469
LIG_FHA_2	652	658	PF00498	0.557
LIG_FHA_2	718	724	PF00498	0.557
LIG_GBD_Chelix_1	288	296	PF00786	0.357
LIG_IBAR_NPY_1	30	32	PF08397	0.686
LIG_LIR_Apic_2	490	494	PF02991	0.467
LIG_LIR_Apic_2	81	85	PF02991	0.555
LIG_LIR_Apic_2	831	835	PF02991	0.522
LIG_LIR_Gen_1	108	117	PF02991	0.525
LIG_LIR_Gen_1	235	243	PF02991	0.484
LIG_LIR_Gen_1	389	399	PF02991	0.470
LIG_LIR_Gen_1	775	783	PF02991	0.487
LIG_LIR_Gen_1	938	947	PF02991	0.481
LIG_LIR_Nem_3	108	112	PF02991	0.467
LIG_LIR_Nem_3	195	201	PF02991	0.385
LIG_LIR_Nem_3	235	240	PF02991	0.484
LIG_LIR_Nem_3	393	399	PF02991	0.498
LIG_LIR_Nem_3	529	535	PF02991	0.525
LIG_LIR_Nem_3	59	65	PF02991	0.486
LIG_LIR_Nem_3	723	729	PF02991	0.488
LIG_LIR_Nem_3	775	780	PF02991	0.454
LIG_LIR_Nem_3	789	794	PF02991	0.433
LIG_LIR_Nem_3	860	865	PF02991	0.484
LIG_LIR_Nem_3	938	943	PF02991	0.481
LIG_LIR_Nem_3	986	992	PF02991	0.498
LIG_MLH1_MIPbox_1	195	199	PF16413	0.473
LIG_MYND_3	63	67	PF01753	0.519
LIG_PAM2_1	812	824	PF00658	0.557
LIG_PCNA_PIPBox_1	960	969	PF02747	0.477
LIG_PDZ_Class_1	1001	1006	PF00595	0.545
LIG_Pex14_1	722	726	PF04695	0.480
LIG_Pex14_1	809	813	PF04695	0.489
LIG_Pex14_2	153	157	PF04695	0.377
LIG_Pex14_2	463	467	PF04695	0.456
LIG_PTB_Apo_2	151	158	PF02174	0.438
LIG_Rb_LxCxE_1	738	757	PF01857	0.498
LIG_REV1ctd_RIR_1	196	206	PF16727	0.385
LIG_SH2_CRK	185	189	PF00017	0.469
LIG_SH2_CRK	32	36	PF00017	0.671
LIG_SH2_CRK	497	501	PF00017	0.438
LIG_SH2_CRK	989	993	PF00017	0.456
LIG_SH2_GRB2like	224	227	PF00017	0.317
LIG_SH2_GRB2like	364	367	PF00017	0.545
LIG_SH2_STAP1	32	36	PF00017	0.590
LIG_SH2_STAP1	364	368	PF00017	0.541
LIG_SH2_STAP1	510	514	PF00017	0.498
LIG_SH2_STAT5	185	188	PF00017	0.388
LIG_SH2_STAT5	20	23	PF00017	0.584
LIG_SH2_STAT5	364	367	PF00017	0.522
LIG_SH2_STAT5	43	46	PF00017	0.440
LIG_SH2_STAT5	430	433	PF00017	0.489
LIG_SH2_STAT5	510	513	PF00017	0.593
LIG_SH2_STAT5	679	682	PF00017	0.509
LIG_SH2_STAT5	820	823	PF00017	0.498
LIG_SH3_3	325	331	PF00018	0.520
LIG_SH3_3	552	558	PF00018	0.605
LIG_SH3_3	574	580	PF00018	0.658
LIG_SH3_3	808	814	PF00018	0.485
LIG_SH3_3	974	980	PF00018	0.483
LIG_Sin3_3	862	869	PF02671	0.557
LIG_SUMO_SIM_anti_2	337	342	PF11976	0.480
LIG_SUMO_SIM_anti_2	906	912	PF11976	0.497
LIG_SUMO_SIM_par_1	505	511	PF11976	0.482
LIG_SUMO_SIM_par_1	690	695	PF11976	0.525
LIG_SUMO_SIM_par_1	906	912	PF11976	0.557
LIG_TRAF2_1	138	141	PF00917	0.417
LIG_TRAF2_1	217	220	PF00917	0.530
LIG_TRAF2_1	521	524	PF00917	0.505
LIG_TRAF2_1	920	923	PF00917	0.394
LIG_TYR_ITIM	223	228	PF00017	0.359
LIG_TYR_ITIM	677	682	PF00017	0.522
LIG_TYR_ITSM	985	992	PF00017	0.456
LIG_UBA3_1	256	261	PF00899	0.449
LIG_UBA3_1	836	842	PF00899	0.394
LIG_UBA3_1	963	970	PF00899	0.522
LIG_WRC_WIRS_1	79	84	PF05994	0.584
MOD_CK1_1	167	173	PF00069	0.479
MOD_CK1_1	212	218	PF00069	0.415
MOD_CK1_1	425	431	PF00069	0.490
MOD_CK1_1	560	566	PF00069	0.657
MOD_CK1_1	695	701	PF00069	0.483
MOD_CK1_1	73	79	PF00069	0.641
MOD_CK1_1	781	787	PF00069	0.504
MOD_CK1_1	83	89	PF00069	0.570
MOD_CK1_1	851	857	PF00069	0.482
MOD_CK1_1	978	984	PF00069	0.488
MOD_CK2_1	342	348	PF00069	0.495
MOD_CK2_1	386	392	PF00069	0.487
MOD_CK2_1	518	524	PF00069	0.488
MOD_CK2_1	583	589	PF00069	0.502
MOD_CK2_1	695	701	PF00069	0.468
MOD_CK2_1	717	723	PF00069	0.538
MOD_CK2_1	739	745	PF00069	0.509
MOD_CK2_1	87	93	PF00069	0.592
MOD_Cter_Amidation	322	325	PF01082	0.277
MOD_GlcNHglycan	122	125	PF01048	0.650
MOD_GlcNHglycan	14	17	PF01048	0.668
MOD_GlcNHglycan	166	169	PF01048	0.510
MOD_GlcNHglycan	195	198	PF01048	0.440
MOD_GlcNHglycan	273	276	PF01048	0.361
MOD_GlcNHglycan	427	430	PF01048	0.343
MOD_GlcNHglycan	54	57	PF01048	0.606
MOD_GlcNHglycan	544	547	PF01048	0.358
MOD_GlcNHglycan	563	566	PF01048	0.597
MOD_GlcNHglycan	568	571	PF01048	0.727
MOD_GlcNHglycan	581	584	PF01048	0.600
MOD_GlcNHglycan	6	9	PF01048	0.744
MOD_GlcNHglycan	70	73	PF01048	0.437
MOD_GlcNHglycan	762	765	PF01048	0.301
MOD_GlcNHglycan	770	773	PF01048	0.301
MOD_GlcNHglycan	882	885	PF01048	0.280
MOD_GlcNHglycan	980	983	PF01048	0.358
MOD_GSK3_1	12	19	PF00069	0.569
MOD_GSK3_1	153	160	PF00069	0.477
MOD_GSK3_1	386	393	PF00069	0.515
MOD_GSK3_1	425	432	PF00069	0.484
MOD_GSK3_1	557	564	PF00069	0.610
MOD_GSK3_1	579	586	PF00069	0.575
MOD_GSK3_1	668	675	PF00069	0.505
MOD_GSK3_1	690	697	PF00069	0.463
MOD_GSK3_1	713	720	PF00069	0.559
MOD_GSK3_1	750	757	PF00069	0.476
MOD_GSK3_1	809	816	PF00069	0.587
MOD_GSK3_1	83	90	PF00069	0.569
MOD_GSK3_1	854	861	PF00069	0.514
MOD_GSK3_1	984	991	PF00069	0.503
MOD_N-GLC_1	153	158	PF02516	0.457
MOD_N-GLC_1	332	337	PF02516	0.345
MOD_N-GLC_1	483	488	PF02516	0.331
MOD_N-GLC_1	561	566	PF02516	0.635
MOD_N-GLC_1	695	700	PF02516	0.289
MOD_N-GLC_1	848	853	PF02516	0.430
MOD_NEK2_1	100	105	PF00069	0.405
MOD_NEK2_1	153	158	PF00069	0.408
MOD_NEK2_1	193	198	PF00069	0.443
MOD_NEK2_1	292	297	PF00069	0.513
MOD_NEK2_1	713	718	PF00069	0.561
MOD_NEK2_1	754	759	PF00069	0.462
MOD_NEK2_1	969	974	PF00069	0.430
MOD_NEK2_2	386	391	PF00069	0.498
MOD_NEK2_2	988	993	PF00069	0.480
MOD_PIKK_1	489	495	PF00454	0.489
MOD_PIKK_1	587	593	PF00454	0.485
MOD_PIKK_1	661	667	PF00454	0.452
MOD_PIKK_1	685	691	PF00454	0.564
MOD_PIKK_1	854	860	PF00454	0.545
MOD_PK_1	599	605	PF00069	0.398
MOD_PKA_1	622	628	PF00069	0.538
MOD_PKA_2	100	106	PF00069	0.466
MOD_PKA_2	12	18	PF00069	0.690
MOD_PKA_2	292	298	PF00069	0.435
MOD_PKA_2	360	366	PF00069	0.519
MOD_PKA_2	425	431	PF00069	0.500
MOD_PKA_2	651	657	PF00069	0.487
MOD_PKA_2	659	665	PF00069	0.481
MOD_PKA_2	83	89	PF00069	0.616
MOD_PKA_2	978	984	PF00069	0.482
MOD_PKB_1	957	965	PF00069	0.522
MOD_Plk_1	147	153	PF00069	0.445
MOD_Plk_1	161	167	PF00069	0.424
MOD_Plk_1	332	338	PF00069	0.545
MOD_Plk_1	368	374	PF00069	0.540
MOD_Plk_1	614	620	PF00069	0.526
MOD_Plk_1	695	701	PF00069	0.452
MOD_Plk_1	749	755	PF00069	0.548
MOD_Plk_2-3	87	93	PF00069	0.613
MOD_Plk_4	100	106	PF00069	0.401
MOD_Plk_4	161	167	PF00069	0.506
MOD_Plk_4	502	508	PF00069	0.474
MOD_Plk_4	510	516	PF00069	0.459
MOD_Plk_4	58	64	PF00069	0.446
MOD_Plk_4	750	756	PF00069	0.456
MOD_Plk_4	885	891	PF00069	0.467
MOD_Plk_4	959	965	PF00069	0.500
MOD_ProDKin_1	683	689	PF00069	0.534
MOD_ProDKin_1	73	79	PF00069	0.643
MOD_ProDKin_1	813	819	PF00069	0.489
MOD_ProDKin_1	898	904	PF00069	0.546
MOD_ProDKin_1	981	987	PF00069	0.464
MOD_SUMO_rev_2	523	527	PF00179	0.554
MOD_SUMO_rev_2	83	91	PF00179	0.645
MOD_SUMO_rev_2	887	896	PF00179	0.477
MOD_SUMO_rev_2	991	1001	PF00179	0.528
TRG_DiLeu_BaEn_1	750	755	PF01217	0.557
TRG_DiLeu_BaEn_1	996	1001	PF01217	0.480
TRG_DiLeu_BaLyEn_6	832	837	PF01217	0.545
TRG_ENDOCYTIC_2	109	112	PF00928	0.447
TRG_ENDOCYTIC_2	225	228	PF00928	0.464
TRG_ENDOCYTIC_2	32	35	PF00928	0.627
TRG_ENDOCYTIC_2	391	394	PF00928	0.460
TRG_ENDOCYTIC_2	497	500	PF00928	0.456
TRG_ENDOCYTIC_2	540	543	PF00928	0.503
TRG_ENDOCYTIC_2	679	682	PF00928	0.509
TRG_ENDOCYTIC_2	820	823	PF00928	0.489
TRG_ENDOCYTIC_2	989	992	PF00928	0.456
TRG_ER_diArg_1	181	183	PF00400	0.421
TRG_ER_diArg_1	2	4	PF00400	0.605
TRG_ER_diArg_1	221	223	PF00400	0.559
TRG_ER_diArg_1	282	285	PF00400	0.489
TRG_ER_diArg_1	478	480	PF00400	0.498
TRG_ER_diArg_1	802	805	PF00400	0.540
TRG_ER_diArg_1	824	826	PF00400	0.489
TRG_ER_diArg_1	956	959	PF00400	0.455
TRG_NES_CRM1_1	637	647	PF08389	0.522
TRG_NLS_MonoExtC_3	620	626	PF00514	0.433
TRG_Pf-PMV_PEXEL_1	135	140	PF00026	0.430
TRG_Pf-PMV_PEXEL_1	89	93	PF00026	0.591

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVP3	Leptomonas seymouri	78%	100%
A0A0N1HXR5	Leptomonas seymouri	39%	99%
A0A0S4JH30	Bodo saltans	39%	100%
A0A0S4JV11	Bodo saltans	52%	98%
A0A1X0P3C5	Trypanosomatidae	39%	100%
A0A1X0P407	Trypanosomatidae	62%	100%
A0A3Q8IEB5	Leishmania donovani	98%	100%
A0A3R7KVU5	Trypanosoma rangeli	38%	100%
A0A3S5IR73	Trypanosoma rangeli	58%	100%
A0A3S7XBB9	Leishmania donovani	40%	99%
A0PVU7	Mycobacterium ulcerans (strain Agy99)	36%	81%
A0R2B1	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	37%	82%
A1KI36	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	36%	82%
A1TDK2	Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1)	37%	81%
A1UK81	Mycobacterium sp. (strain KMS)	37%	79%
A2ATU0	Mus musculus	35%	100%
A3Q3N5	Mycobacterium sp. (strain JLS)	37%	80%
A4HFL1	Leishmania braziliensis	89%	100%
A4HPL4	Leishmania braziliensis	40%	99%
A4I2P6	Leishmania infantum	98%	100%
A4ID50	Leishmania infantum	40%	99%
A5ISU5	Staphylococcus aureus (strain JH9)	35%	100%
A5U1U6	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	36%	82%
A5VSQ0	Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)	38%	100%
A6QGW6	Staphylococcus aureus (strain Newman)	35%	100%
A6U1N4	Staphylococcus aureus (strain JH1)	35%	100%
A6WXF0	Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37)	38%	100%
A7GMD4	Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)	35%	100%
A7X295	Staphylococcus aureus (strain Mu3 / ATCC 700698)	35%	100%
A7Z5J9	Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)	34%	100%
A8FE66	Bacillus pumilus (strain SAFR-032)	34%	100%
A8Z3Z0	Staphylococcus aureus (strain USA300 / TCH1516)	35%	100%
A9M8Q9	Brucella canis (strain ATCC 23365 / NCTC 10854)	38%	100%
A9VJX9	Bacillus mycoides (strain KBAB4)	35%	100%
B0CIS7	Brucella suis (strain ATCC 23445 / NCTC 10510)	38%	100%
B2S877	Brucella abortus (strain S19)	38%	100%
B7HH19	Bacillus cereus (strain B4264)	35%	100%
B7I0H2	Bacillus cereus (strain AH187)	35%	100%
B7IM94	Bacillus cereus (strain G9842)	35%	100%
B7JEU9	Bacillus cereus (strain AH820)	35%	100%
B9IU58	Bacillus cereus (strain Q1)	35%	100%
C0RFG8	Brucella melitensis biotype 2 (strain ATCC 23457)	38%	100%
C1ELG5	Bacillus cereus (strain 03BB102)	35%	100%
C3LAU3	Bacillus anthracis (strain CDC 684 / NRRL 3495)	35%	100%
C3P487	Bacillus anthracis (strain A0248)	35%	100%
C4L3W2	Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b)	34%	100%
C5D802	Geobacillus sp. (strain WCH70)	36%	100%
D0A5T7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
D0A8K0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
D3ZQD3	Rattus norvegicus	38%	100%
E9ATC6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	99%
E9AYZ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
O61199	Caenorhabditis elegans	36%	98%
O74378	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	100%
P0AFG3	Escherichia coli (strain K12)	35%	100%
P0AFG4	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	35%	100%
P0AFG5	Escherichia coli O157:H7	35%	100%
P0C601	Staphylococcus aureus	35%	100%
P20707	Azotobacter vinelandii	36%	100%
P20967	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	99%
P23129	Bacillus subtilis (strain 168)	34%	100%
P45303	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	37%	100%
P51056	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	36%	100%
P57388	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	33%	100%
P9WIS4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	36%	82%
P9WIS5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	36%	82%
Q02218	Homo sapiens	37%	98%
Q148N0	Bos taurus	37%	98%
Q1B4V6	Mycobacterium sp. (strain MCS)	37%	79%
Q1RHI4	Rickettsia bellii (strain RML369-C)	36%	100%
Q23629	Caenorhabditis elegans	35%	100%
Q2FH25	Staphylococcus aureus (strain USA300)	35%	100%
Q2FYM1	Staphylococcus aureus (strain NCTC 8325 / PS 47)	35%	100%
Q2YLS2	Brucella abortus (strain 2308)	38%	100%
Q2YY05	Staphylococcus aureus (strain bovine RF122 / ET3-1)	34%	100%
Q49XM5	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	33%	100%
Q4KLP0	Rattus norvegicus	36%	100%
Q4L6C4	Staphylococcus haemolyticus (strain JCSC1435)	34%	100%
Q4Q171	Leishmania major	40%	100%
Q4UKI8	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)	37%	100%
Q54JE4	Dictyostelium discoideum	39%	99%
Q54VG0	Dictyostelium discoideum	33%	100%
Q57AX5	Brucella abortus biovar 1 (strain 9-941)	38%	100%
Q59106	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	37%	100%
Q5HG06	Staphylococcus aureus (strain COL)	35%	100%
Q5HPC6	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	34%	100%
Q5L172	Geobacillus kaustophilus (strain HTA426)	36%	100%
Q5PRA2	Danio rerio	36%	100%
Q5R7H0	Pongo abelii	34%	100%
Q5R9L8	Pongo abelii	37%	100%
Q5RCB8	Pongo abelii	37%	98%
Q5WG56	Alkalihalobacillus clausii (strain KSM-K16)	36%	100%
Q5XI78	Rattus norvegicus	37%	98%
Q60597	Mus musculus	36%	98%
Q60HE2	Macaca fascicularis	37%	98%
Q623T0	Caenorhabditis briggsae	38%	98%
Q63EB1	Bacillus cereus (strain ZK / E33L)	35%	100%
Q65IH4	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	34%	100%
Q68EW0	Xenopus laevis	36%	99%
Q68XI7	Rickettsia typhi (strain ATCC VR-144 / Wilmington)	37%	100%
Q6G9E8	Staphylococcus aureus (strain MSSA476)	35%	100%
Q6GGZ5	Staphylococcus aureus (strain MRSA252)	35%	100%
Q6HLS8	Bacillus thuringiensis subsp. konkukian (strain 97-27)	35%	100%
Q6P286	Xenopus laevis	34%	100%
Q6P6Z8	Xenopus laevis	37%	99%
Q72PJ7	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	36%	100%
Q73BN8	Bacillus cereus (strain ATCC 10987 / NRS 248)	35%	100%
Q73WX4	Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)	36%	81%
Q7U0A6	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	36%	82%
Q81GF2	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	35%	100%
Q81TK1	Bacillus anthracis	35%	100%
Q89AJ7	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	33%	100%
Q8CP83	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	34%	100%
Q8CUL8	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	35%	100%
Q8F6S7	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	36%	100%
Q8FYF7	Brucella suis biovar 1 (strain 1330)	38%	100%
Q8K9N3	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	35%	100%
Q8NRC3	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	38%	82%
Q8NWR6	Staphylococcus aureus (strain MW2)	35%	100%
Q8YJE4	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	38%	100%
Q92J42	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	36%	100%
Q931R8	Staphylococcus aureus (strain Mu50 / ATCC 700699)	35%	100%
Q96HY7	Homo sapiens	36%	100%
Q99U74	Staphylococcus aureus (strain N315)	35%	100%
Q9CC97	Mycobacterium leprae (strain TN)	36%	81%
Q9KAT1	Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	36%	100%
Q9ULD0	Homo sapiens	38%	100%
Q9VA02	Drosophila melanogaster	34%	100%
Q9ZDY3	Rickettsia prowazekii (strain Madrid E)	36%	100%
V5BIL1	Trypanosoma cruzi	60%	100%
V5BWU3	Trypanosoma cruzi	38%	100%