LeishMANIAdb
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ULP_PROTEASE domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
ULP_PROTEASE domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
E9AD20_LEIMA
TriTrypDb:
LmjF.27.0430 , LMJLV39_270009300 , LMJSD75_270009300
Length:
610

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0000776 kinetochore 3 2
GO:0043226 organelle 2 2
GO:0043228 non-membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043232 intracellular non-membrane-bounded organelle 4 2
GO:0099080 supramolecular complex 2 2
GO:0110165 cellular anatomical entity 1 2
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Expansion

Sequence features

E9AD20
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AD20

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 354 358 PF00656 0.642
CLV_C14_Caspase3-7 427 431 PF00656 0.719
CLV_C14_Caspase3-7 513 517 PF00656 0.687
CLV_NRD_NRD_1 157 159 PF00675 0.562
CLV_NRD_NRD_1 192 194 PF00675 0.594
CLV_NRD_NRD_1 20 22 PF00675 0.632
CLV_NRD_NRD_1 210 212 PF00675 0.614
CLV_NRD_NRD_1 235 237 PF00675 0.654
CLV_NRD_NRD_1 297 299 PF00675 0.684
CLV_NRD_NRD_1 322 324 PF00675 0.562
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HX23 Leptomonas seymouri 70% 100%
A0A1X0P3W6 Trypanosomatidae 36% 84%
A0A3Q8IE02 Leishmania donovani 95% 100%
A4HFG7 Leishmania braziliensis 84% 100%
A4I2M9 Leishmania infantum 95% 100%
E9AYU5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
V5BSQ4 Trypanosoma cruzi 35% 91%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS