Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ACY3_LEIMA

TriTrypDb:

LmjF.27.0060 , LMJLV39_270005700 , LMJSD75_270005600

Length:

106

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

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Expansion

Sequence features

E9ACY3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACY3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	102	104	PF00675	0.569
CLV_NRD_NRD_1	80	82	PF00675	0.438
CLV_NRD_NRD_1	83	85	PF00675	0.434
CLV_PCSK_FUR_1	81	85	PF00082	0.368
CLV_PCSK_KEX2_1	80	82	PF00082	0.438
CLV_PCSK_KEX2_1	83	85	PF00082	0.434
CLV_PCSK_SKI1_1	84	88	PF00082	0.454
DEG_SCF_FBW7_1	11	17	PF00400	0.384
DOC_CKS1_1	11	16	PF01111	0.384
DOC_MAPK_DCC_7	28	37	PF00069	0.406

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A4HFC5	Leishmania braziliensis	80%	100%
A4I2K2	Leishmania infantum	91%	100%
E9AYQ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	72%

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