DEAD-box helicase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DEAD-box helicase-like protein

Species:

Leishmania major

UniProt:

E9ACY2_LEIMA

TriTrypDb:

LmjF.27.0050 , LMJLV39_270005600 , LMJSD75_270005500

Length:

788

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	3
GO:0016020	membrane	2	1

Expansion

Sequence features

E9ACY2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACY2

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	2
GO:0022613	ribonucleoprotein complex biogenesis	4	2
GO:0042254	ribosome biogenesis	5	2
GO:0044085	cellular component biogenesis	3	2
GO:0071840	cellular component organization or biogenesis	2	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	11
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016787	hydrolase activity	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	125	129	PF00656	0.577
CLV_C14_Caspase3-7	330	334	PF00656	0.489
CLV_C14_Caspase3-7	385	389	PF00656	0.390
CLV_C14_Caspase3-7	399	403	PF00656	0.276
CLV_C14_Caspase3-7	463	467	PF00656	0.647
CLV_C14_Caspase3-7	469	473	PF00656	0.600
CLV_NRD_NRD_1	256	258	PF00675	0.250
CLV_NRD_NRD_1	313	315	PF00675	0.348
CLV_NRD_NRD_1	344	346	PF00675	0.516
CLV_NRD_NRD_1	40	42	PF00675	0.625
CLV_NRD_NRD_1	420	422	PF00675	0.575
CLV_NRD_NRD_1	513	515	PF00675	0.342
CLV_NRD_NRD_1	605	607	PF00675	0.423
CLV_NRD_NRD_1	723	725	PF00675	0.572
CLV_NRD_NRD_1	760	762	PF00675	0.598
CLV_NRD_NRD_1	771	773	PF00675	0.577
CLV_PCSK_KEX2_1	323	325	PF00082	0.250
CLV_PCSK_KEX2_1	344	346	PF00082	0.539
CLV_PCSK_KEX2_1	420	422	PF00082	0.590
CLV_PCSK_KEX2_1	740	742	PF00082	0.665
CLV_PCSK_KEX2_1	770	772	PF00082	0.613
CLV_PCSK_PC1ET2_1	323	325	PF00082	0.250
CLV_PCSK_PC1ET2_1	740	742	PF00082	0.728
CLV_PCSK_PC1ET2_1	770	772	PF00082	0.613
CLV_PCSK_PC7_1	736	742	PF00082	0.634
CLV_PCSK_SKI1_1	143	147	PF00082	0.423
CLV_PCSK_SKI1_1	323	327	PF00082	0.250
CLV_PCSK_SKI1_1	426	430	PF00082	0.671
CLV_PCSK_SKI1_1	483	487	PF00082	0.296
CLV_PCSK_SKI1_1	520	524	PF00082	0.289
CLV_PCSK_SKI1_1	598	602	PF00082	0.446
CLV_PCSK_SKI1_1	658	662	PF00082	0.318
CLV_PCSK_SKI1_1	679	683	PF00082	0.311
CLV_PCSK_SKI1_1	761	765	PF00082	0.553
DEG_APCC_DBOX_1	256	264	PF00400	0.527
DEG_APCC_KENBOX_2	652	656	PF00400	0.216
DOC_CDC14_PxL_1	127	135	PF14671	0.521
DOC_CKS1_1	264	269	PF01111	0.461
DOC_CYCLIN_RxL_1	215	226	PF00134	0.536
DOC_CYCLIN_RxL_1	676	686	PF00134	0.411
DOC_CYCLIN_RxL_1	773	787	PF00134	0.652
DOC_MAPK_DCC_7	773	783	PF00069	0.720
DOC_MAPK_gen_1	253	262	PF00069	0.450
DOC_MAPK_gen_1	303	311	PF00069	0.475
DOC_MAPK_gen_1	373	382	PF00069	0.330
DOC_MAPK_gen_1	514	524	PF00069	0.494
DOC_MAPK_gen_1	738	746	PF00069	0.621
DOC_MAPK_gen_1	83	91	PF00069	0.707
DOC_MAPK_MEF2A_6	205	214	PF00069	0.461
DOC_MAPK_MEF2A_6	255	264	PF00069	0.461
DOC_MAPK_MEF2A_6	364	372	PF00069	0.495
DOC_MAPK_MEF2A_6	373	382	PF00069	0.421
DOC_PP1_RVXF_1	157	163	PF00149	0.475
DOC_PP1_RVXF_1	391	398	PF00149	0.341
DOC_PP1_RVXF_1	518	525	PF00149	0.473
DOC_PP1_RVXF_1	535	541	PF00149	0.415
DOC_PP1_RVXF_1	677	684	PF00149	0.360
DOC_PP1_RVXF_1	777	784	PF00149	0.585
DOC_PP2B_LxvP_1	533	536	PF13499	0.450
DOC_PP4_FxxP_1	357	360	PF00568	0.454
DOC_PP4_FxxP_1	572	575	PF00568	0.349
DOC_USP7_MATH_1	434	438	PF00917	0.628
DOC_USP7_MATH_1	663	667	PF00917	0.260
DOC_USP7_UBL2_3	617	621	PF12436	0.383
DOC_USP7_UBL2_3	67	71	PF12436	0.688
DOC_USP7_UBL2_3	773	777	PF12436	0.701
DOC_WW_Pin1_4	198	203	PF00397	0.555
DOC_WW_Pin1_4	263	268	PF00397	0.450
DOC_WW_Pin1_4	413	418	PF00397	0.398
DOC_WW_Pin1_4	54	59	PF00397	0.563
DOC_WW_Pin1_4	698	703	PF00397	0.419
DOC_WW_Pin1_4	99	104	PF00397	0.676
LIG_14-3-3_CanoR_1	143	151	PF00244	0.434
LIG_14-3-3_CanoR_1	337	343	PF00244	0.373
LIG_14-3-3_CanoR_1	375	379	PF00244	0.356
LIG_14-3-3_CanoR_1	420	424	PF00244	0.651
LIG_14-3-3_CanoR_1	432	437	PF00244	0.575
LIG_14-3-3_CanoR_1	514	524	PF00244	0.551
LIG_14-3-3_CanoR_1	676	682	PF00244	0.417
LIG_14-3-3_CanoR_1	751	756	PF00244	0.508
LIG_Actin_WH2_2	292	308	PF00022	0.536
LIG_BIR_II_1	1	5	PF00653	0.612
LIG_BRCT_BRCA1_1	402	406	PF00533	0.328
LIG_BRCT_BRCA1_1	520	524	PF00533	0.555
LIG_BRCT_BRCA1_1	568	572	PF00533	0.345
LIG_BRCT_BRCA1_1	679	683	PF00533	0.423
LIG_FHA_1	104	110	PF00498	0.770
LIG_FHA_1	207	213	PF00498	0.466
LIG_FHA_1	215	221	PF00498	0.472
LIG_FHA_1	223	229	PF00498	0.417
LIG_FHA_1	330	336	PF00498	0.450
LIG_FHA_1	354	360	PF00498	0.485
LIG_FHA_1	402	408	PF00498	0.439
LIG_FHA_1	453	459	PF00498	0.705
LIG_FHA_1	476	482	PF00498	0.495
LIG_FHA_1	549	555	PF00498	0.468
LIG_FHA_1	558	564	PF00498	0.433
LIG_FHA_1	583	589	PF00498	0.514
LIG_FHA_1	628	634	PF00498	0.361
LIG_FHA_1	676	682	PF00498	0.372
LIG_FHA_1	684	690	PF00498	0.271
LIG_FHA_2	123	129	PF00498	0.566
LIG_FHA_2	328	334	PF00498	0.509
LIG_FHA_2	458	464	PF00498	0.588
LIG_FHA_2	467	473	PF00498	0.582
LIG_FHA_2	614	620	PF00498	0.391
LIG_LIR_Apic_2	183	189	PF02991	0.450
LIG_LIR_Apic_2	355	360	PF02991	0.467
LIG_LIR_Apic_2	569	575	PF02991	0.345
LIG_LIR_Gen_1	2	10	PF02991	0.635
LIG_LIR_Gen_1	403	414	PF02991	0.408
LIG_LIR_Gen_1	460	468	PF02991	0.706
LIG_LIR_Gen_1	605	615	PF02991	0.404
LIG_LIR_Gen_1	749	756	PF02991	0.643
LIG_LIR_Nem_3	2	7	PF02991	0.640
LIG_LIR_Nem_3	403	409	PF02991	0.337
LIG_LIR_Nem_3	460	464	PF02991	0.712
LIG_LIR_Nem_3	577	583	PF02991	0.366
LIG_LIR_Nem_3	605	611	PF02991	0.382
LIG_MLH1_MIPbox_1	679	683	PF16413	0.423
LIG_NRBOX	18	24	PF00104	0.604
LIG_NRBOX	190	196	PF00104	0.450
LIG_NRBOX	375	381	PF00104	0.442
LIG_PCNA_yPIPBox_3	700	713	PF02747	0.519
LIG_PDZ_Class_2	783	788	PF00595	0.584
LIG_Pex14_1	540	544	PF04695	0.450
LIG_RPA_C_Fungi	767	779	PF08784	0.653
LIG_SH2_CRK	186	190	PF00017	0.300
LIG_SH2_CRK	544	548	PF00017	0.303
LIG_SH2_NCK_1	186	190	PF00017	0.423
LIG_SH2_PTP2	367	370	PF00017	0.422
LIG_SH2_PTP2	4	7	PF00017	0.654
LIG_SH2_SRC	367	370	PF00017	0.251
LIG_SH2_SRC	544	547	PF00017	0.303
LIG_SH2_STAP1	580	584	PF00017	0.418
LIG_SH2_STAP1	608	612	PF00017	0.394
LIG_SH2_STAT5	367	370	PF00017	0.394
LIG_SH2_STAT5	4	7	PF00017	0.654
LIG_SH2_STAT5	408	411	PF00017	0.382
LIG_SH2_STAT5	553	556	PF00017	0.303
LIG_SH2_STAT5	583	586	PF00017	0.394
LIG_SH2_STAT5	614	617	PF00017	0.368
LIG_SH2_STAT5	667	670	PF00017	0.332
LIG_SH2_STAT5	712	715	PF00017	0.589
LIG_SH3_1	544	550	PF00018	0.360
LIG_SH3_3	261	267	PF00018	0.388
LIG_SH3_3	365	371	PF00018	0.431
LIG_SH3_3	544	550	PF00018	0.360
LIG_SH3_3	55	61	PF00018	0.637
LIG_SH3_3	78	84	PF00018	0.684
LIG_SUMO_SIM_anti_2	209	215	PF11976	0.298
LIG_SUMO_SIM_par_1	260	266	PF11976	0.337
LIG_UBA3_1	141	150	PF00899	0.532
LIG_UBA3_1	270	275	PF00899	0.327
LIG_UBA3_1	296	303	PF00899	0.341
LIG_UBA3_1	308	315	PF00899	0.277
LIG_UBA3_1	36	42	PF00899	0.669
LIG_UBA3_1	612	617	PF00899	0.402
LIG_WRC_WIRS_1	379	384	PF05994	0.343
LIG_WRC_WIRS_1	458	463	PF05994	0.586
LIG_WRC_WIRS_1	608	613	PF05994	0.377
MOD_CDK_SPxK_1	263	269	PF00069	0.303
MOD_CDK_SPxxK_3	198	205	PF00069	0.450
MOD_CDK_SPxxK_3	413	420	PF00069	0.506
MOD_CK1_1	180	186	PF00069	0.295
MOD_CK1_1	3	9	PF00069	0.652
MOD_CK1_1	358	364	PF00069	0.474
MOD_CK1_1	518	524	PF00069	0.429
MOD_CK1_1	566	572	PF00069	0.464
MOD_CK1_1	74	80	PF00069	0.674
MOD_CK1_1	754	760	PF00069	0.673
MOD_CK1_1	99	105	PF00069	0.699
MOD_CK2_1	21	27	PF00069	0.646
MOD_CK2_1	462	468	PF00069	0.588
MOD_CK2_1	67	73	PF00069	0.700
MOD_CK2_1	698	704	PF00069	0.450
MOD_CK2_1	87	93	PF00069	0.724
MOD_GlcNHglycan	111	114	PF01048	0.659
MOD_GlcNHglycan	179	182	PF01048	0.309
MOD_GlcNHglycan	27	31	PF01048	0.674
MOD_GlcNHglycan	327	330	PF01048	0.298
MOD_GlcNHglycan	436	439	PF01048	0.698
MOD_GlcNHglycan	565	568	PF01048	0.513
MOD_GlcNHglycan	7	10	PF01048	0.674
MOD_GlcNHglycan	73	76	PF01048	0.744
MOD_GlcNHglycan	98	101	PF01048	0.773
MOD_GSK3_1	115	122	PF00069	0.431
MOD_GSK3_1	173	180	PF00069	0.290
MOD_GSK3_1	22	29	PF00069	0.604
MOD_GSK3_1	222	229	PF00069	0.314
MOD_GSK3_1	274	281	PF00069	0.407
MOD_GSK3_1	325	332	PF00069	0.303
MOD_GSK3_1	355	362	PF00069	0.496
MOD_GSK3_1	374	381	PF00069	0.186
MOD_GSK3_1	396	403	PF00069	0.351
MOD_GSK3_1	409	416	PF00069	0.402
MOD_GSK3_1	428	435	PF00069	0.611
MOD_GSK3_1	462	469	PF00069	0.690
MOD_GSK3_1	67	74	PF00069	0.609
MOD_GSK3_1	677	684	PF00069	0.411
MOD_GSK3_1	724	731	PF00069	0.616
MOD_GSK3_1	95	102	PF00069	0.681
MOD_N-GLC_1	30	35	PF02516	0.607
MOD_N-GLC_1	52	57	PF02516	0.725
MOD_N-GLC_2	730	732	PF02516	0.512
MOD_NEK2_1	109	114	PF00069	0.684
MOD_NEK2_1	119	124	PF00069	0.553
MOD_NEK2_1	145	150	PF00069	0.516
MOD_NEK2_1	274	279	PF00069	0.303
MOD_NEK2_1	382	387	PF00069	0.347
MOD_NEK2_1	409	414	PF00069	0.436
MOD_NEK2_1	441	446	PF00069	0.540
MOD_NEK2_1	587	592	PF00069	0.548
MOD_NEK2_1	613	618	PF00069	0.417
MOD_NEK2_1	627	632	PF00069	0.351
MOD_NEK2_1	681	686	PF00069	0.407
MOD_PIKK_1	350	356	PF00454	0.577
MOD_PIKK_1	382	388	PF00454	0.353
MOD_PIKK_1	587	593	PF00454	0.548
MOD_PIKK_1	754	760	PF00454	0.656
MOD_PKA_1	71	77	PF00069	0.652
MOD_PKA_1	724	730	PF00069	0.688
MOD_PKA_1	761	767	PF00069	0.570
MOD_PKA_1	772	778	PF00069	0.593
MOD_PKA_1	95	101	PF00069	0.728
MOD_PKA_2	119	125	PF00069	0.615
MOD_PKA_2	336	342	PF00069	0.373
MOD_PKA_2	374	380	PF00069	0.358
MOD_PKA_2	419	425	PF00069	0.590
MOD_PKA_2	513	519	PF00069	0.379
MOD_PKA_2	675	681	PF00069	0.333
MOD_PKB_1	430	438	PF00069	0.683
MOD_Plk_1	518	524	PF00069	0.443
MOD_Plk_1	52	58	PF00069	0.547
MOD_Plk_2-3	457	463	PF00069	0.593
MOD_Plk_2-3	466	472	PF00069	0.591
MOD_Plk_4	206	212	PF00069	0.299
MOD_Plk_4	227	233	PF00069	0.327
MOD_Plk_4	284	290	PF00069	0.303
MOD_Plk_4	374	380	PF00069	0.343
MOD_Plk_4	518	524	PF00069	0.450
MOD_Plk_4	549	555	PF00069	0.396
MOD_Plk_4	566	572	PF00069	0.232
MOD_Plk_4	607	613	PF00069	0.370
MOD_Plk_4	663	669	PF00069	0.268
MOD_Plk_4	677	683	PF00069	0.303
MOD_Plk_4	751	757	PF00069	0.571
MOD_ProDKin_1	198	204	PF00069	0.450
MOD_ProDKin_1	263	269	PF00069	0.303
MOD_ProDKin_1	413	419	PF00069	0.409
MOD_ProDKin_1	54	60	PF00069	0.563
MOD_ProDKin_1	698	704	PF00069	0.419
MOD_ProDKin_1	99	105	PF00069	0.676
MOD_SUMO_for_1	149	152	PF00179	0.502
MOD_SUMO_rev_2	320	325	PF00179	0.333
MOD_SUMO_rev_2	422	428	PF00179	0.690
MOD_SUMO_rev_2	590	600	PF00179	0.594
MOD_SUMO_rev_2	90	97	PF00179	0.744
TRG_DiLeu_BaEn_1	292	297	PF01217	0.303
TRG_DiLeu_BaEn_1	307	312	PF01217	0.303
TRG_DiLeu_BaEn_1	405	410	PF01217	0.458
TRG_DiLeu_BaLyEn_6	18	23	PF01217	0.664
TRG_DiLeu_BaLyEn_6	190	195	PF01217	0.423
TRG_DiLeu_BaLyEn_6	266	271	PF01217	0.309
TRG_DiLeu_LyEn_5	292	297	PF01217	0.303
TRG_ENDOCYTIC_2	367	370	PF00928	0.337
TRG_ENDOCYTIC_2	4	7	PF00928	0.658
TRG_ENDOCYTIC_2	608	611	PF00928	0.400
TRG_ENDOCYTIC_2	671	674	PF00928	0.423
TRG_ENDOCYTIC_2	752	755	PF00928	0.550
TRG_ER_diArg_1	343	345	PF00400	0.517
TRG_ER_diArg_1	741	744	PF00400	0.662
TRG_NLS_Bipartite_1	724	744	PF00514	0.709
TRG_NLS_MonoExtC_3	513	519	PF00514	0.255
TRG_NLS_MonoExtC_3	739	745	PF00514	0.681
TRG_NLS_MonoExtN_4	738	744	PF00514	0.686
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.449
TRG_Pf-PMV_PEXEL_1	193	197	PF00026	0.401
TRG_Pf-PMV_PEXEL_1	218	223	PF00026	0.316
TRG_Pf-PMV_PEXEL_1	303	307	PF00026	0.344
TRG_Pf-PMV_PEXEL_1	717	722	PF00026	0.570
TRG_Pf-PMV_PEXEL_1	761	766	PF00026	0.681

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1U1	Leptomonas seymouri	78%	100%
A0A0N1PCZ7	Leptomonas seymouri	22%	100%
A0A0S4ISP4	Bodo saltans	49%	100%
A0A1X0NMD6	Trypanosomatidae	53%	96%
A0A1X0NPK0	Trypanosomatidae	25%	79%
A0A3Q8IE53	Leishmania donovani	93%	100%
A0A3R7N587	Trypanosoma rangeli	54%	96%
A0A3R7NJH7	Trypanosoma rangeli	23%	100%
A0A3S5H7C7	Leishmania donovani	24%	100%
A1CB55	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	32%	100%
A1DE84	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	30%	100%
A2RA55	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	32%	100%
A2XVF7	Oryza sativa subsp. indica	27%	95%
A3AVH5	Oryza sativa subsp. japonica	27%	95%
A3LWH3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	30%	100%
A4H481	Leishmania braziliensis	27%	100%
A4HD81	Leishmania braziliensis	22%	100%
A4HFC4	Leishmania braziliensis	87%	100%
A4I2K1	Leishmania infantum	93%	100%
A5DAR2	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	34%	100%
A6RSH5	Botryotinia fuckeliana (strain B05.10)	32%	90%
A6ZZY8	Saccharomyces cerevisiae (strain YJM789)	31%	100%
A7F8V8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	32%	90%
A7TNT1	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	31%	100%
C9ZKU1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	53%	89%
E9AH36	Leishmania infantum	24%	100%
E9AWL4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AYQ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
O60173	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P0CQ94	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	28%	83%
P0CQ95	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	28%	83%
P36120	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	100%
Q0CF43	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	100%
Q0UHM7	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	95%
Q0UZ59	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	26%	100%
Q1E9T9	Coccidioides immitis (strain RS)	32%	100%
Q2GZU7	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	30%	98%
Q2UE66	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	33%	100%
Q4HZ68	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	31%	100%
Q4P0Y5	Ustilago maydis (strain 521 / FGSC 9021)	30%	81%
Q4QAV6	Leishmania major	23%	100%
Q4WV71	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	30%	100%
Q59S50	Candida albicans (strain SC5314 / ATCC MYA-2876)	31%	100%
Q5BGX6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	100%
Q6BKH3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	31%	99%
Q6C835	Yarrowia lipolytica (strain CLIB 122 / E 150)	32%	99%
Q6CK32	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	31%	100%
Q6NZQ2	Mus musculus	34%	100%
Q754J2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	100%
Q7S873	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	29%	97%
Q7XJN0	Arabidopsis thaliana	33%	100%
Q869P0	Dictyostelium discoideum	35%	87%
Q86B47	Drosophila melanogaster	33%	81%
Q8TFL3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	31%	100%
Q9H8H2	Homo sapiens	34%	93%
V5BG99	Trypanosoma cruzi	53%	95%