Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

calcium/calmodulin-dependent protein kinase, putative

Species:

Leishmania major

UniProt:

E9ACW6_LEIMA

TriTrypDb:

LmjF.27.2460 , LMJLV39_270032400 , LMJSD75_270032300

Length:

299

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005737	cytoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9ACW6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACW6

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	10
GO:0006793	phosphorus metabolic process	3	10
GO:0006796	phosphate-containing compound metabolic process	4	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0007165	signal transduction	2	2
GO:0008152	metabolic process	1	10
GO:0009987	cellular process	1	10
GO:0016310	phosphorylation	5	10
GO:0018105	peptidyl-serine phosphorylation	6	2
GO:0018193	peptidyl-amino acid modification	5	2
GO:0018209	peptidyl-serine modification	6	2
GO:0019538	protein metabolic process	3	10
GO:0035556	intracellular signal transduction	3	2
GO:0036211	protein modification process	4	10
GO:0043170	macromolecule metabolic process	3	10
GO:0043412	macromolecule modification	4	10
GO:0044237	cellular metabolic process	2	10
GO:0044238	primary metabolic process	2	10
GO:0046777	protein autophosphorylation	6	2
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0065007	biological regulation	1	2
GO:0071704	organic substance metabolic process	2	10
GO:1901564	organonitrogen compound metabolic process	3	10

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003824	catalytic activity	1	10
GO:0004672	protein kinase activity	3	10
GO:0004674	protein serine/threonine kinase activity	4	2
GO:0004683	calmodulin-dependent protein kinase activity	5	2
GO:0005488	binding	1	10
GO:0005515	protein binding	2	2
GO:0005516	calmodulin binding	3	2
GO:0005524	ATP binding	5	10
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5	2
GO:0010857	calcium-dependent protein kinase activity	4	2
GO:0016301	kinase activity	4	10
GO:0016740	transferase activity	2	10
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	10
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:0140096	catalytic activity, acting on a protein	2	10
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	174	176	PF00675	0.408
CLV_NRD_NRD_1	47	49	PF00675	0.327
CLV_PCSK_KEX2_1	174	176	PF00082	0.408
CLV_PCSK_KEX2_1	284	286	PF00082	0.340
CLV_PCSK_KEX2_1	33	35	PF00082	0.366
CLV_PCSK_KEX2_1	47	49	PF00082	0.214
CLV_PCSK_PC1ET2_1	284	286	PF00082	0.338
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.450
CLV_PCSK_SKI1_1	11	15	PF00082	0.369
CLV_PCSK_SKI1_1	113	117	PF00082	0.299
CLV_PCSK_SKI1_1	130	134	PF00082	0.309
CLV_PCSK_SKI1_1	289	293	PF00082	0.450
CLV_PCSK_SKI1_1	34	38	PF00082	0.405
DEG_APCC_DBOX_1	112	120	PF00400	0.306
DEG_SCF_FBW7_1	277	283	PF00400	0.379
DEG_SPOP_SBC_1	139	143	PF00917	0.326
DOC_CDC14_PxL_1	62	70	PF14671	0.418
DOC_CKS1_1	277	282	PF01111	0.349
DOC_MAPK_gen_1	130	139	PF00069	0.322
DOC_MAPK_gen_1	47	53	PF00069	0.371
DOC_MAPK_MEF2A_6	70	78	PF00069	0.465
DOC_USP7_MATH_1	280	284	PF00917	0.349
DOC_USP7_MATH_1	43	47	PF00917	0.427
DOC_USP7_UBL2_3	33	37	PF12436	0.427
DOC_WW_Pin1_4	181	186	PF00397	0.306
DOC_WW_Pin1_4	240	245	PF00397	0.306
DOC_WW_Pin1_4	259	264	PF00397	0.396
DOC_WW_Pin1_4	276	281	PF00397	0.272
LIG_14-3-3_CanoR_1	140	149	PF00244	0.264
LIG_14-3-3_CanoR_1	200	208	PF00244	0.300
LIG_14-3-3_CanoR_1	213	223	PF00244	0.429
LIG_14-3-3_CanoR_1	96	103	PF00244	0.461
LIG_APCC_ABBA_1	72	77	PF00400	0.395
LIG_BIR_II_1	1	5	PF00653	0.483
LIG_Clathr_ClatBox_1	236	240	PF01394	0.379
LIG_deltaCOP1_diTrp_1	221	230	PF00928	0.418
LIG_FHA_1	159	165	PF00498	0.405
LIG_FHA_1	171	177	PF00498	0.286
LIG_FHA_1	232	238	PF00498	0.387
LIG_FHA_1	247	253	PF00498	0.197
LIG_FHA_2	241	247	PF00498	0.294
LIG_FHA_2	3	9	PF00498	0.367
LIG_GBD_Chelix_1	111	119	PF00786	0.325
LIG_KLC1_Yacidic_2	73	77	PF13176	0.367
LIG_LIR_Apic_2	184	190	PF02991	0.306
LIG_LIR_Gen_1	10	20	PF02991	0.523
LIG_LIR_Gen_1	245	256	PF02991	0.348
LIG_LIR_Gen_1	73	83	PF02991	0.417
LIG_LIR_Gen_1	92	102	PF02991	0.335
LIG_LIR_Nem_3	10	15	PF02991	0.518
LIG_LIR_Nem_3	245	251	PF02991	0.325
LIG_LIR_Nem_3	73	78	PF02991	0.465
LIG_LIR_Nem_3	92	97	PF02991	0.364
LIG_SH2_CRK	12	16	PF00017	0.511
LIG_SH2_CRK	94	98	PF00017	0.450
LIG_SH2_NCK_1	187	191	PF00017	0.349
LIG_SH2_NCK_1	201	205	PF00017	0.349
LIG_SH2_PTP2	75	78	PF00017	0.326
LIG_SH2_SRC	75	78	PF00017	0.447
LIG_SH2_STAP1	12	16	PF00017	0.511
LIG_SH2_STAT5	75	78	PF00017	0.337
LIG_SH3_1	60	66	PF00018	0.418
LIG_SH3_3	179	185	PF00018	0.306
LIG_SH3_3	60	66	PF00018	0.418
LIG_SUMO_SIM_anti_2	117	123	PF11976	0.418
LIG_SUMO_SIM_anti_2	191	196	PF11976	0.341
LIG_SUMO_SIM_anti_2	79	86	PF11976	0.450
LIG_SUMO_SIM_par_1	161	168	PF11976	0.411
LIG_TRAF2_1	52	55	PF00917	0.418
MOD_CDC14_SPxK_1	262	265	PF00782	0.223
MOD_CDK_SPxK_1	259	265	PF00069	0.223
MOD_CDK_SPxxK_3	264	271	PF00069	0.347
MOD_CK1_1	144	150	PF00069	0.404
MOD_CK1_1	158	164	PF00069	0.457
MOD_CK1_1	2	8	PF00069	0.497
MOD_CK1_1	29	35	PF00069	0.317
MOD_CK2_1	185	191	PF00069	0.379
MOD_CK2_1	2	8	PF00069	0.371
MOD_CK2_1	284	290	PF00069	0.379
MOD_GlcNHglycan	157	160	PF01048	0.443
MOD_GlcNHglycan	187	190	PF01048	0.418
MOD_GlcNHglycan	223	226	PF01048	0.348
MOD_GlcNHglycan	268	271	PF01048	0.395
MOD_GlcNHglycan	286	289	PF01048	0.176
MOD_GSK3_1	138	145	PF00069	0.422
MOD_GSK3_1	155	162	PF00069	0.340
MOD_GSK3_1	181	188	PF00069	0.353
MOD_GSK3_1	199	206	PF00069	0.232
MOD_GSK3_1	23	30	PF00069	0.346
MOD_GSK3_1	276	283	PF00069	0.325
MOD_NEK2_1	138	143	PF00069	0.450
MOD_NEK2_1	58	63	PF00069	0.387
MOD_PKA_1	284	290	PF00069	0.325
MOD_PKA_2	139	145	PF00069	0.450
MOD_PKA_2	199	205	PF00069	0.417
MOD_PKA_2	23	29	PF00069	0.392
MOD_PKA_2	284	290	PF00069	0.306
MOD_PKA_2	79	85	PF00069	0.391
MOD_PKA_2	95	101	PF00069	0.320
MOD_Plk_4	159	165	PF00069	0.408
MOD_Plk_4	79	85	PF00069	0.350
MOD_Plk_4	89	95	PF00069	0.256
MOD_ProDKin_1	181	187	PF00069	0.306
MOD_ProDKin_1	240	246	PF00069	0.306
MOD_ProDKin_1	259	265	PF00069	0.396
MOD_ProDKin_1	276	282	PF00069	0.272
MOD_SUMO_for_1	132	135	PF00179	0.306
TRG_DiLeu_BaEn_2	9	15	PF01217	0.544
TRG_ENDOCYTIC_2	12	15	PF00928	0.519
TRG_ENDOCYTIC_2	75	78	PF00928	0.324
TRG_ENDOCYTIC_2	94	97	PF00928	0.327
TRG_ER_diArg_1	174	176	PF00400	0.408
TRG_NES_CRM1_1	67	79	PF08389	0.367
TRG_Pf-PMV_PEXEL_1	213	218	PF00026	0.391

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P215	Leptomonas seymouri	26%	100%
A0A0N0P3N5	Leptomonas seymouri	26%	70%
A0A0N0P3Q8	Leptomonas seymouri	28%	84%
A0A0N0P787	Leptomonas seymouri	25%	77%
A0A0N0P8H5	Leptomonas seymouri	23%	90%
A0A0N0P8X6	Leptomonas seymouri	29%	77%
A0A0N1I4Y7	Leptomonas seymouri	31%	89%
A0A0N1I6Q7	Leptomonas seymouri	28%	67%
A0A0N1I6T8	Leptomonas seymouri	25%	100%
A0A0N1IHY4	Leptomonas seymouri	24%	73%
A0A0N1IIF9	Leptomonas seymouri	22%	100%
A0A0N1IMI0	Leptomonas seymouri	64%	100%
A0A0N1PC31	Leptomonas seymouri	25%	77%
A0A0N1PCH4	Leptomonas seymouri	24%	91%
A0A0S4IHW4	Bodo saltans	28%	66%
A0A0S4IKY7	Bodo saltans	25%	86%
A0A0S4IMB7	Bodo saltans	26%	67%
A0A0S4IQX7	Bodo saltans	29%	77%
A0A0S4IRG0	Bodo saltans	27%	100%
A0A0S4ISS4	Bodo saltans	29%	96%
A0A0S4IX86	Bodo saltans	26%	70%
A0A0S4IZY3	Bodo saltans	22%	89%
A0A0S4J444	Bodo saltans	27%	74%
A0A0S4J4B3	Bodo saltans	25%	67%
A0A0S4J4X4	Bodo saltans	29%	99%
A0A0S4J6L4	Bodo saltans	26%	78%
A0A0S4J9Q7	Bodo saltans	28%	66%
A0A0S4JA09	Bodo saltans	24%	73%
A0A0S4JBR3	Bodo saltans	25%	95%
A0A0S4JCG2	Bodo saltans	23%	67%
A0A0S4JDD3	Bodo saltans	26%	69%
A0A0S4JK24	Bodo saltans	28%	69%
A0A0S4JPZ1	Bodo saltans	25%	67%
A0A0S4JPZ7	Bodo saltans	25%	71%
A0A0S4JUJ2	Bodo saltans	25%	100%
A0A0S4JWD5	Bodo saltans	27%	76%
A0A0S4JZV2	Bodo saltans	28%	89%
A0A0S4KFT7	Bodo saltans	23%	89%
A0A0S4KHR9	Bodo saltans	28%	90%
A0A0S4KN74	Bodo saltans	28%	92%
A0A1X0NG10	Trypanosomatidae	39%	100%
A0A1X0NIA0	Trypanosomatidae	25%	70%
A0A1X0NIX2	Trypanosomatidae	25%	68%
A0A1X0NLN7	Trypanosomatidae	26%	89%
A0A1X0NQ63	Trypanosomatidae	25%	100%
A0A1X0NRZ9	Trypanosomatidae	27%	81%
A0A1X0NW24	Trypanosomatidae	28%	85%
A0A1X0NY93	Trypanosomatidae	25%	76%
A0A1X0P020	Trypanosomatidae	24%	77%
A0A1X0P5B1	Trypanosomatidae	22%	91%
A0A1X0P5F2	Trypanosomatidae	24%	91%
A0A1X0P6V1	Trypanosomatidae	24%	100%
A0A1X0P735	Trypanosomatidae	23%	100%
A0A1X0P7V0	Trypanosomatidae	23%	89%
A0A1X0P935	Trypanosomatidae	28%	81%
A0A1X0PAW2	Trypanosomatidae	26%	84%
A0A3Q8IAQ1	Leishmania donovani	24%	84%
A0A3Q8IB30	Leishmania donovani	23%	90%
A0A3Q8IBT5	Leishmania donovani	28%	100%
A0A3Q8IFK8	Leishmania donovani	25%	68%
A0A3Q8IFW0	Leishmania donovani	26%	70%
A0A3Q8IIG1	Leishmania donovani	30%	77%
A0A3Q8INQ4	Leishmania donovani	26%	77%
A0A3R7KCZ4	Trypanosoma rangeli	27%	74%
A0A3R7KMF0	Trypanosoma rangeli	27%	84%
A0A3R7M1U6	Trypanosoma rangeli	27%	80%
A0A3R7M5C7	Trypanosoma rangeli	26%	100%
A0A3R7M819	Trypanosoma rangeli	29%	85%
A0A3R7MHW5	Trypanosoma rangeli	28%	75%
A0A3R7MJP3	Trypanosoma rangeli	38%	100%
A0A3R7MKG5	Trypanosoma rangeli	26%	68%
A0A3R7NLI6	Trypanosoma rangeli	25%	81%
A0A3S5H5G0	Leishmania donovani	27%	69%
A0A3S5H606	Leishmania donovani	25%	100%
A0A3S5H789	Leishmania donovani	27%	100%
A0A3S7WUX5	Leishmania donovani	24%	100%
A0A3S7WWE7	Leishmania donovani	26%	100%
A0A3S7WYP4	Leishmania donovani	27%	85%
A0A3S7X123	Leishmania donovani	93%	100%
A0A3S7X7Y2	Leishmania donovani	28%	78%
A0A3S7X9R4	Leishmania donovani	24%	81%
A0A3S7X9S2	Leishmania donovani	24%	88%
A0A422N3Y6	Trypanosoma rangeli	26%	67%
A0A422NCX4	Trypanosoma rangeli	27%	76%
A0A422NDD2	Trypanosoma rangeli	27%	86%
A0A422NJ30	Trypanosoma rangeli	25%	100%
A0A422P0J2	Trypanosoma rangeli	22%	89%
A0A422P0N6	Trypanosoma rangeli	29%	96%
A0A422P1R5	Trypanosoma rangeli	24%	97%
A0A422P4L8	Trypanosoma rangeli	29%	70%
A0A8I3S724	Canis lupus familiaris	25%	74%
A2YNT8	Oryza sativa subsp. indica	29%	88%
A2ZAB5	Oryza sativa subsp. indica	28%	90%
A4H539	Leishmania braziliensis	25%	100%
A4H9H4	Leishmania braziliensis	24%	100%
A4H9L8	Leishmania braziliensis	23%	90%
A4HAS1	Leishmania braziliensis	28%	78%
A4HDU3	Leishmania braziliensis	28%	85%
A4HED7	Leishmania braziliensis	25%	77%
A4HFI2	Leishmania braziliensis	25%	91%
A4HG26	Leishmania braziliensis	84%	100%
A4HH03	Leishmania braziliensis	32%	78%
A4HJT5	Leishmania braziliensis	25%	68%
A4HJW2	Leishmania braziliensis	26%	70%
A4HN71	Leishmania braziliensis	23%	80%
A4HSE2	Leishmania infantum	27%	69%
A4HTB4	Leishmania infantum	25%	100%
A4HXU0	Leishmania infantum	24%	100%
A4HXY2	Leishmania infantum	23%	90%
A4HYX6	Leishmania infantum	27%	100%
A4HZA2	Leishmania infantum	26%	100%
A4HZW8	Leishmania infantum	24%	84%
A4I140	Leishmania infantum	27%	85%
A4I1T4	Leishmania infantum	26%	77%
A4I435	Leishmania infantum	31%	77%
A4I7A1	Leishmania infantum	25%	68%
A4I7C4	Leishmania infantum	26%	70%
A4I9Y5	Leishmania infantum	28%	78%
A4IBT4	Leishmania infantum	23%	78%
A4IBT9	Leishmania infantum	24%	81%
A5GFW1	Sus scrofa	27%	74%
A8X6H4	Caenorhabditis briggsae	29%	84%
A9TF79	Physcomitrium patens	29%	86%
B0LT89	Rattus norvegicus	28%	69%
C9ZIZ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	66%
C9ZJM0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZK98	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	69%
C9ZL78	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	71%
C9ZLJ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	80%
C9ZMH9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	68%
C9ZPX9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	85%
C9ZUK8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
C9ZW68	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	85%
C9ZWI1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	69%
C9ZWK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	68%
C9ZZX0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
C9ZZX1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
D0A0D6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	77%
D0A2M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	96%
D0A2R4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	79%
D0A5C6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	89%
D0A8X3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	81%
D0N4E2	Phytophthora infestans (strain T30-4)	27%	75%
E8NHS0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	84%
E9AFM1	Leishmania major	24%	88%
E9AKB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	69%
E9ALA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9ARK2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9ARP5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	90%
E9AX78	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	85%
E9AXW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	77%
E9AZF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
E9B0C2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	78%
E9B296	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	68%
E9B2B7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	70%
E9B4Z4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	78%
E9B6S4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	78%
E9B6S9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	81%
F4I1N8	Arabidopsis thaliana	26%	73%
O00506	Homo sapiens	29%	70%
O02827	Ovis aries	26%	68%
O08875	Rattus norvegicus	28%	69%
O14408	Metarhizium anisopliae	29%	78%
O14965	Homo sapiens	26%	74%
O22932	Arabidopsis thaliana	25%	69%
O54784	Mus musculus	26%	67%
O59697	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	71%
O59790	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	84%
O64812	Arabidopsis thaliana	30%	88%
O65554	Arabidopsis thaliana	26%	68%
O70150	Rattus norvegicus	26%	87%
O88764	Rattus norvegicus	26%	67%
O94768	Homo sapiens	26%	80%
P00518	Oryctolagus cuniculus	25%	77%
P07934	Mus musculus	25%	77%
P0C5D6	Oryza sativa subsp. japonica	28%	90%
P11801	Homo sapiens	28%	71%
P13286	Rattus norvegicus	25%	77%
P15735	Homo sapiens	27%	74%
P22517	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	67%
P25323	Dictyostelium discoideum	27%	100%
P27466	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	67%
P31325	Rattus norvegicus	26%	74%
P38991	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	81%
P43291	Arabidopsis thaliana	27%	82%
P43292	Arabidopsis thaliana	28%	85%
P49071	Drosophila melanogaster	27%	83%
P49136	Cricetulus longicaudatus	26%	91%
P49137	Homo sapiens	26%	75%
P49138	Mus musculus	26%	77%
P49139	Oryctolagus cuniculus	26%	82%
Q00771	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	29%	72%
Q02066	Triticum aestivum	28%	90%
Q07250	Malus domestica	30%	72%
Q09136	Sus scrofa	27%	78%
Q0D4J7	Oryza sativa subsp. japonica	29%	88%
Q0V7M1	Bos taurus	28%	71%
Q10292	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	67%
Q14012	Homo sapiens	26%	81%
Q16644	Homo sapiens	28%	78%
Q16816	Homo sapiens	25%	77%
Q27687	Leishmania major	23%	90%
Q2KJ16	Bos taurus	26%	74%
Q2QY53	Oryza sativa subsp. japonica	25%	68%
Q2TA06	Bos taurus	26%	74%
Q2V452	Arabidopsis thaliana	26%	68%
Q39192	Arabidopsis thaliana	30%	83%
Q39193	Arabidopsis thaliana	30%	83%
Q3SWY6	Bos taurus	29%	70%
Q3SYZ2	Bos taurus	28%	78%
Q3UMW7	Mus musculus	28%	78%
Q4KTY1	Pinctada fucata	26%	72%
Q4Q2Z2	Leishmania major	28%	78%
Q4Q5T9	Leishmania major	26%	70%
Q4Q5W2	Leishmania major	26%	68%
Q4Q7W2	Leishmania major	29%	77%
Q4Q9K2	Leishmania major	26%	77%
Q4QA98	Leishmania major	26%	85%
Q4QBQ2	Leishmania major	24%	84%
Q4QDX7	Leishmania major	24%	100%
Q4QIJ7	Leishmania major	25%	100%
Q4QJJ0	Leishmania major	27%	69%
Q501V0	Danio rerio	28%	71%
Q54CY9	Dictyostelium discoideum	28%	96%
Q54SJ5	Dictyostelium discoideum	28%	96%
Q54WX4	Dictyostelium discoideum	24%	78%
Q5HZ38	Arabidopsis thaliana	30%	73%
Q5JLD8	Oryza sativa subsp. japonica	26%	67%
Q5N942	Oryza sativa subsp. japonica	28%	83%
Q5SUV5	Mus musculus	25%	77%
Q61XD3	Caenorhabditis briggsae	24%	99%
Q63450	Rattus norvegicus	26%	80%
Q66H84	Rattus norvegicus	29%	78%
Q69Q47	Oryza sativa subsp. japonica	26%	66%
Q6C3J2	Yarrowia lipolytica (strain CLIB 122 / E 150)	25%	81%
Q6CWQ4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	26%	83%
Q6P2M8	Homo sapiens	27%	87%
Q6X4A2	Oryza sativa subsp. japonica	26%	67%
Q6ZI44	Oryza sativa subsp. japonica	28%	82%
Q6ZLP5	Oryza sativa subsp. japonica	24%	66%
Q75H77	Oryza sativa subsp. japonica	28%	83%
Q75LR7	Oryza sativa subsp. japonica	28%	87%
Q75V57	Oryza sativa subsp. japonica	27%	83%
Q7XIW5	Oryza sativa subsp. japonica	26%	67%
Q7XKA8	Oryza sativa subsp. japonica	29%	81%
Q7XQP4	Oryza sativa subsp. japonica	28%	83%
Q7Y0B9	Oryza sativa subsp. japonica	28%	81%
Q84VQ3	Arabidopsis thaliana	26%	68%
Q869W6	Dictyostelium discoideum	25%	86%
Q86AD7	Dictyostelium discoideum	28%	76%
Q86YV6	Homo sapiens	26%	77%
Q8BG48	Mus musculus	26%	80%
Q8BHI9	Mus musculus	27%	69%
Q8BW96	Mus musculus	26%	78%
Q8GVC7	Phytophthora infestans	27%	75%
Q8IU85	Homo sapiens	26%	78%
Q8IY84	Homo sapiens	25%	69%
Q8LIG4	Oryza sativa subsp. japonica	26%	67%
Q8RWC9	Arabidopsis thaliana	27%	67%
Q8VDF3	Mus musculus	27%	81%
Q91XS8	Rattus norvegicus	26%	81%
Q91YA2	Mus musculus	28%	71%
Q91YS8	Mus musculus	26%	80%
Q93V58	Arabidopsis thaliana	28%	76%
Q93VK0	Arabidopsis thaliana	34%	100%
Q940H6	Arabidopsis thaliana	30%	83%
Q94C40	Arabidopsis thaliana	26%	69%
Q965G5	Caenorhabditis elegans	28%	82%
Q96PN8	Homo sapiens	28%	100%
Q96QS6	Homo sapiens	25%	78%
Q99KH8	Mus musculus	28%	69%
Q9C958	Arabidopsis thaliana	27%	83%
Q9D2E1	Mus musculus	28%	100%
Q9DB30	Mus musculus	26%	74%
Q9FFP9	Arabidopsis thaliana	28%	83%
Q9GM70	Oryctolagus cuniculus	26%	75%
Q9GNR4	Leishmania major	24%	81%
Q9LDI3	Arabidopsis thaliana	25%	67%
Q9LEU7	Arabidopsis thaliana	26%	67%
Q9M9E9	Arabidopsis thaliana	29%	87%
Q9MAM1	Arabidopsis thaliana	26%	67%
Q9P7I2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	89%
Q9QYK9	Mus musculus	26%	87%
Q9S7U9	Arabidopsis thaliana	26%	82%
Q9SMQ4	Arabidopsis thaliana	27%	85%
Q9SPK4	Arabidopsis thaliana	32%	100%
Q9STV4	Arabidopsis thaliana	25%	67%
Q9SUL7	Arabidopsis thaliana	26%	70%
Q9TXJ0	Caenorhabditis elegans	29%	86%
Q9UEE5	Homo sapiens	26%	72%
Q9UIK4	Homo sapiens	26%	81%
Q9Y6E0	Homo sapiens	28%	67%
Q9Y899	Emericella nidulans	29%	74%
Q9YHZ5	Danio rerio	28%	96%
Q9Z2W1	Mus musculus	29%	70%
V5BCH2	Trypanosoma cruzi	26%	76%
V5BEK5	Trypanosoma cruzi	23%	89%
V5BFI8	Trypanosoma cruzi	27%	67%
V5BFK9	Trypanosoma cruzi	38%	100%
V5BJT8	Trypanosoma cruzi	26%	91%
V5BKJ3	Trypanosoma cruzi	28%	84%
V5BMH5	Trypanosoma cruzi	28%	90%
V5BNV8	Trypanosoma cruzi	24%	100%
V5BQF4	Trypanosoma cruzi	28%	80%
V5BWC2	Trypanosoma cruzi	24%	100%
V5BX61	Trypanosoma cruzi	28%	80%
V5D579	Trypanosoma cruzi	25%	70%
V5D9M1	Trypanosoma cruzi	27%	81%
V5DAY8	Trypanosoma cruzi	26%	72%
V5DI55	Trypanosoma cruzi	28%	72%
V5DTI8	Trypanosoma cruzi	25%	76%
V5DUQ7	Trypanosoma cruzi	27%	79%
W0LYS5	Macrobrachium nipponense	26%	87%