Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

E9ACV8_LEIMA

TriTrypDb:

LmjF.27.2380 , LMJLV39_270031600 , LMJSD75_270031500

Length:

156


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	7
GO:0110165	cellular anatomical entity	1	7

E9ACV8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACV8


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	76	80	PF00082	0.346
DEG_MDM2_SWIB_1	110	117	PF02201	0.411
DEG_SPOP_SBC_1	12	16	PF00917	0.519
DOC_MAPK_MEF2A_6	135	142	PF00069	0.618
DOC_USP7_MATH_1	12	16	PF00917	0.534
DOC_USP7_MATH_1	123	127	PF00917	0.726
DOC_WW_Pin1_4	124	129	PF00397	0.654
LIG_14-3-3_CanoR_1	13	18	PF00244	0.516
LIG_BIR_II_1	1	5	PF00653	0.555
LIG_deltaCOP1_diTrp_1	97	104	PF00928	0.359
LIG_FHA_1	45	51	PF00498	0.457
LIG_FHA_1	88	94	PF00498	0.411
LIG_LIR_Gen_1	131	141	PF02991	0.546
LIG_LIR_Nem_3	131	136	PF02991	0.637
LIG_Pex14_2	110	114	PF04695	0.411
LIG_Pex14_2	55	59	PF04695	0.411
LIG_SH2_SRC	141	144	PF00017	0.411
LIG_SH2_STAP1	46	50	PF00017	0.389
LIG_SH2_STAT3	149	152	PF00017	0.512
LIG_SH2_STAT5	133	136	PF00017	0.629
LIG_SH2_STAT5	141	144	PF00017	0.411
LIG_SH2_STAT5	46	49	PF00017	0.405
LIG_SH3_3	131	137	PF00018	0.631
LIG_SUMO_SIM_anti_2	35	40	PF11976	0.327
LIG_SUMO_SIM_anti_2	49	54	PF11976	0.415
LIG_SUMO_SIM_anti_2	90	97	PF11976	0.411
LIG_SUMO_SIM_par_1	47	54	PF11976	0.389
LIG_WRC_WIRS_1	52	57	PF05994	0.411
MOD_CDC14_SPxK_1	127	130	PF00782	0.647
MOD_CDK_SPxK_1	124	130	PF00069	0.659
MOD_CK1_1	126	132	PF00069	0.674
MOD_CK1_1	16	22	PF00069	0.221
MOD_GlcNHglycan	56	59	PF01048	0.461
MOD_GlcNHglycan	73	76	PF01048	0.471
MOD_GSK3_1	12	19	PF00069	0.530
MOD_GSK3_1	30	37	PF00069	0.333
MOD_GSK3_1	40	47	PF00069	0.404
MOD_GSK3_1	89	96	PF00069	0.409
MOD_NEK2_1	30	35	PF00069	0.276
MOD_NEK2_1	44	49	PF00069	0.460
MOD_NEK2_1	71	76	PF00069	0.723
MOD_NEK2_1	89	94	PF00069	0.315
MOD_PKA_2	12	18	PF00069	0.518
MOD_Plk_4	13	19	PF00069	0.413
MOD_Plk_4	34	40	PF00069	0.336
MOD_Plk_4	89	95	PF00069	0.381
MOD_ProDKin_1	124	130	PF00069	0.647
TRG_ENDOCYTIC_2	133	136	PF00928	0.629


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I817	Leptomonas seymouri	56%	100%
A0A3S7X132	Leishmania donovani	94%	100%
A4HG18	Leishmania braziliensis	80%	100%
E9AHG3	Leishmania infantum	93%	100%
E9AZE7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%