Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ACV2_LEIMA

TriTrypDb:

LmjF.27.2335

Length:

160


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

E9ACV2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACV2


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	89	93	PF00656	0.706
CLV_NRD_NRD_1	116	118	PF00675	0.554
CLV_PCSK_FUR_1	117	121	PF00082	0.449
CLV_PCSK_KEX2_1	119	121	PF00082	0.542
CLV_PCSK_PC1ET2_1	119	121	PF00082	0.542
CLV_PCSK_SKI1_1	105	109	PF00082	0.531
LIG_14-3-3_CanoR_1	26	34	PF00244	0.608
LIG_BIR_II_1	1	5	PF00653	0.711
LIG_Clathr_ClatBox_1	42	46	PF01394	0.531
LIG_FHA_1	154	160	PF00498	0.678
LIG_LIR_Gen_1	50	57	PF02991	0.584
LIG_LIR_Nem_3	50	56	PF02991	0.588
LIG_PCNA_yPIPBox_3	59	68	PF02747	0.476
LIG_PDZ_Class_2	155	160	PF00595	0.747
LIG_SH2_PTP2	53	56	PF00017	0.597
LIG_SH2_STAT5	53	56	PF00017	0.537
LIG_SH2_STAT5	67	70	PF00017	0.371
LIG_SUMO_SIM_anti_2	48	58	PF11976	0.496
LIG_SUMO_SIM_par_1	86	92	PF11976	0.747
LIG_TRAF2_1	107	110	PF00917	0.596
LIG_TRAF2_1	76	79	PF00917	0.702
MOD_CK1_1	22	28	PF00069	0.649
MOD_CK2_1	57	63	PF00069	0.443
MOD_CK2_1	73	79	PF00069	0.672
MOD_CK2_1	83	89	PF00069	0.680
MOD_GlcNHglycan	129	132	PF01048	0.568
MOD_GlcNHglycan	28	31	PF01048	0.735
MOD_GlcNHglycan	75	78	PF01048	0.511
MOD_GSK3_1	134	141	PF00069	0.659
MOD_GSK3_1	22	29	PF00069	0.708
MOD_N-GLC_1	153	158	PF02516	0.680
MOD_NEK2_1	1	6	PF00069	0.487
MOD_NEK2_1	57	62	PF00069	0.491
MOD_PIKK_1	138	144	PF00454	0.743
MOD_PKA_2	20	26	PF00069	0.621
MOD_PKA_2	71	77	PF00069	0.623
MOD_Plk_1	153	159	PF00069	0.679
MOD_Plk_4	83	89	PF00069	0.735
TRG_DiLeu_BaEn_1	109	114	PF01217	0.515
TRG_ENDOCYTIC_2	53	56	PF00928	0.597
TRG_Pf-PMV_PEXEL_1	120	124	PF00026	0.468


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NQZ0	Trypanosomatidae	36%	82%
A0A3R7K6D4	Trypanosoma rangeli	33%	98%
A0A3S7X104	Leishmania donovani	90%	100%
A4HG12	Leishmania braziliensis	78%	100%
A4I331	Leishmania infantum	89%	100%
C9ZJK4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	66%
E9AZE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
V5B8D3	Trypanosoma cruzi	38%	91%