LeishMANIAdb
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MORN repeat family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
MORN repeat family protein
Gene product:
MORN repeat, putative
Species:
Leishmania major
UniProt:
E9ACU8_LEIMA
TriTrypDb:
LmjF.27.2305 , LMJLV39_270030600 , LMJSD75_270030500
Length:
182

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 16
NetGPI no yes: 0, no: 16
Cellular components
Term Name Level Count
GO:0005930 axoneme 2 3
GO:0097542 ciliary tip 2 2
GO:0110165 cellular anatomical entity 1 3
GO:0005737 cytoplasm 2 1

Expansion

Sequence features

E9ACU8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACU8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 4 6 PF00675 0.611
CLV_PCSK_KEX2_1 162 164 PF00082 0.416
CLV_PCSK_KEX2_1 4 6 PF00082 0.631
CLV_PCSK_PC1ET2_1 162 164 PF00082 0.416
CLV_PCSK_PC1ET2_1 4 6 PF00082 0.631
DEG_SPOP_SBC_1 68 72 PF00917 0.545
DEG_SPOP_SBC_1 88 92 PF00917 0.247
DOC_PP2B_LxvP_1 110 113 PF13499 0.389
DOC_USP7_MATH_1 136 140 PF00917 0.260
DOC_USP7_MATH_1 45 49 PF00917 0.671
DOC_USP7_MATH_1 68 72 PF00917 0.671
DOC_USP7_MATH_1 88 92 PF00917 0.575
DOC_USP7_UBL2_3 28 32 PF12436 0.559
LIG_14-3-3_CanoR_1 18 25 PF00244 0.472
LIG_APCC_ABBA_1 153 158 PF00400 0.389
LIG_FHA_1 105 111 PF00498 0.369
LIG_FHA_1 44 50 PF00498 0.697
LIG_PDZ_Class_2 177 182 PF00595 0.460
LIG_Pex14_1 164 168 PF04695 0.394
LIG_SH2_CRK 84 88 PF00017 0.507
LIG_SH2_STAT5 118 121 PF00017 0.265
LIG_SH2_STAT5 156 159 PF00017 0.248
LIG_SUMO_SIM_par_1 107 114 PF11976 0.252
MOD_CK1_1 111 117 PF00069 0.299
MOD_CK1_1 20 26 PF00069 0.454
MOD_CK1_1 41 47 PF00069 0.670
MOD_CK1_1 48 54 PF00069 0.684
MOD_CK2_1 136 142 PF00069 0.268
MOD_CK2_1 20 26 PF00069 0.409
MOD_Cter_Amidation 160 163 PF01082 0.304
MOD_GlcNHglycan 113 116 PF01048 0.296
MOD_GlcNHglycan 40 43 PF01048 0.590
MOD_GlcNHglycan 71 74 PF01048 0.661
MOD_GlcNHglycan 91 94 PF01048 0.409
MOD_GSK3_1 104 111 PF00069 0.321
MOD_GSK3_1 13 20 PF00069 0.529
MOD_GSK3_1 41 48 PF00069 0.620
MOD_GSK3_1 64 71 PF00069 0.711
MOD_NEK2_1 104 109 PF00069 0.391
MOD_NEK2_1 127 132 PF00069 0.275
MOD_NEK2_1 13 18 PF00069 0.451
MOD_NEK2_1 87 92 PF00069 0.509
MOD_PKA_2 116 122 PF00069 0.409
MOD_PKA_2 17 23 PF00069 0.391
MOD_Plk_4 136 142 PF00069 0.338
MOD_Plk_4 20 26 PF00069 0.414
MOD_SUMO_for_1 178 181 PF00179 0.458
TRG_ENDOCYTIC_2 84 87 PF00928 0.461

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I749 Leptomonas seymouri 38% 71%
A0A0N1IB90 Leptomonas seymouri 62% 100%
A0A0S4KPG9 Bodo saltans 33% 92%
A0A1X0NSQ0 Trypanosomatidae 40% 100%
A0A3Q8IQ71 Leishmania donovani 96% 100%
A0A3S5H6F3 Leishmania donovani 33% 82%
A0A422NAN4 Trypanosoma rangeli 38% 100%
A4HUC7 Leishmania infantum 34% 82%
A4I327 Leishmania infantum 96% 100%
C9ZJK1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 38% 100%
E9AI39 Leishmania braziliensis 36% 85%
E9AZD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
Q4QHJ9 Leishmania major 33% 82%
Q6VTH5 Cyprinus carpio 31% 83%
V5BCY8 Trypanosoma cruzi 38% 100%
V5BX28 Trypanosoma cruzi 32% 71%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS