Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ACU4_LEIMA

TriTrypDb:

LmjF.27.2270 , LMJLV39_270030200 , LMJSD75_270030100

Length:

664

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ACU4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACU4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.652
CLV_C14_Caspase3-7	283	287	PF00656	0.640
CLV_C14_Caspase3-7	401	405	PF00656	0.704
CLV_C14_Caspase3-7	541	545	PF00656	0.476
CLV_NRD_NRD_1	160	162	PF00675	0.644
CLV_NRD_NRD_1	224	226	PF00675	0.657
CLV_NRD_NRD_1	274	276	PF00675	0.618
CLV_NRD_NRD_1	360	362	PF00675	0.797
CLV_NRD_NRD_1	379	381	PF00675	0.516
CLV_NRD_NRD_1	411	413	PF00675	0.671

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I823	Leptomonas seymouri	42%	94%
A0A3S7X108	Leishmania donovani	90%	100%
A4HG04	Leishmania braziliensis	71%	99%
A4I323	Leishmania infantum	90%	100%
E9AZD3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%

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