LeishMANIAdb
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Syntaxin-6_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Syntaxin-6_N domain-containing protein
Gene product:
hypothetical protein
Species:
Leishmania major
UniProt:
E9ACT3_LEIMA
TriTrypDb:
LmjF.26.1015
Length:
65

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ACT3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACT3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 17 21 PF00656 0.460
LIG_14-3-3_CterR_2 61 65 PF00244 0.574
LIG_BIR_II_1 1 5 PF00653 0.692
LIG_BRCT_BRCA1_1 1 5 PF00533 0.633
LIG_FHA_2 15 21 PF00498 0.484
LIG_FHA_2 4 10 PF00498 0.575
LIG_LIR_Gen_1 2 11 PF02991 0.559
LIG_LIR_Nem_3 2 8 PF02991 0.585
LIG_SH2_SRC 18 21 PF00017 0.398
LIG_SH2_STAT5 18 21 PF00017 0.592
MOD_CK1_1 3 9 PF00069 0.620
MOD_GlcNHglycan 36 39 PF01048 0.594
MOD_NEK2_1 1 6 PF00069 0.677
MOD_NEK2_1 19 24 PF00069 0.400
MOD_NEK2_1 34 39 PF00069 0.450
MOD_PIKK_1 19 25 PF00454 0.608
MOD_PIKK_1 45 51 PF00454 0.577
MOD_Plk_2-3 14 20 PF00069 0.492
MOD_Plk_4 14 20 PF00069 0.531

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IDR0 Leishmania donovani 89% 100%
A4HEV7 Leishmania braziliensis 75% 93%
E9AHB4 Leishmania infantum 88% 100%
E9AY80 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS