LapA_dom domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ACS8_LEIMA

TriTrypDb:

LmjF.24.0555 , LMJLV39_240011200 , LMJSD75_240010800

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

E9ACS8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACS8


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	42	44	PF00675	0.450
CLV_NRD_NRD_1	87	89	PF00675	0.464
CLV_PCSK_KEX2_1	42	44	PF00082	0.450
CLV_PCSK_PC7_1	38	44	PF00082	0.436
DEG_Nend_UBRbox_2	1	3	PF02207	0.413
DOC_USP7_MATH_1	80	84	PF00917	0.684
LIG_CaM_IQ_9	30	46	PF13499	0.496
LIG_FHA_1	11	17	PF00498	0.405
LIG_LIR_Gen_1	4	14	PF02991	0.398
LIG_LIR_Nem_3	4	9	PF02991	0.493
LIG_NRP_CendR_1	89	92	PF00754	0.419
LIG_SUMO_SIM_par_1	18	23	PF11976	0.383
MOD_CK1_1	28	34	PF00069	0.290
MOD_CK1_1	81	87	PF00069	0.752
MOD_CK2_1	49	55	PF00069	0.624
MOD_GSK3_1	80	87	PF00069	0.666
MOD_N-GLC_1	67	72	PF02516	0.520
MOD_N-GLC_1	81	86	PF02516	0.403
MOD_NEK2_1	49	54	PF00069	0.624
MOD_NEK2_1	8	13	PF00069	0.365
MOD_Plk_1	81	87	PF00069	0.681
MOD_Plk_4	20	26	PF00069	0.304
TRG_NLS_MonoExtC_3	87	92	PF00514	0.615


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZK7	Leptomonas seymouri	43%	100%
A0A3S7WY55	Leishmania donovani	94%	100%
A4HDB5	Leishmania braziliensis	64%	100%
E9AH56	Leishmania infantum	95%	100%
E9AWP7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%