Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ACS2_LEIMA

TriTrypDb:

LmjF.23.0223 , LMJLV39_230007300 , LMJSD75_230007600

Length:

152


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

E9ACS2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACS2


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	2	4	PF00675	0.488
CLV_PCSK_KEX2_1	126	128	PF00082	0.645
CLV_PCSK_KEX2_1	2	4	PF00082	0.488
CLV_PCSK_PC1ET2_1	126	128	PF00082	0.645
DEG_Nend_UBRbox_1	1	4	PF02207	0.668
DEG_SPOP_SBC_1	49	53	PF00917	0.614
DOC_CKS1_1	67	72	PF01111	0.677
DOC_PP1_RVXF_1	1	8	PF00149	0.675
DOC_PP4_FxxP_1	109	112	PF00568	0.398
DOC_USP7_MATH_1	13	17	PF00917	0.652
DOC_USP7_MATH_1	20	24	PF00917	0.662
DOC_USP7_MATH_1	49	53	PF00917	0.621
DOC_WW_Pin1_4	66	71	PF00397	0.647
DOC_WW_Pin1_4	83	88	PF00397	0.587
LIG_14-3-3_CanoR_1	25	31	PF00244	0.686
LIG_14-3-3_CanoR_1	60	67	PF00244	0.655
LIG_BRCT_BRCA1_1	44	48	PF00533	0.657
LIG_FHA_2	84	90	PF00498	0.676
LIG_SH2_STAT5	116	119	PF00017	0.520
LIG_SH3_3	64	70	PF00018	0.692
LIG_SUMO_SIM_anti_2	102	108	PF11976	0.398
MOD_CDK_SPxK_1	66	72	PF00069	0.677
MOD_CK1_1	23	29	PF00069	0.658
MOD_CK1_1	52	58	PF00069	0.669
MOD_CK2_1	141	147	PF00069	0.502
MOD_CK2_1	83	89	PF00069	0.677
MOD_CK2_1	92	98	PF00069	0.659
MOD_GlcNHglycan	118	121	PF01048	0.671
MOD_GlcNHglycan	17	20	PF01048	0.479
MOD_GlcNHglycan	36	39	PF01048	0.350
MOD_GlcNHglycan	57	60	PF01048	0.472
MOD_GlcNHglycan	98	102	PF01048	0.398
MOD_GSK3_1	20	27	PF00069	0.683
MOD_GSK3_1	36	43	PF00069	0.602
MOD_GSK3_1	48	55	PF00069	0.610
MOD_GSK3_1	92	99	PF00069	0.655
MOD_NEK2_1	40	45	PF00069	0.653
MOD_NEK2_1	48	53	PF00069	0.606
MOD_NEK2_2	20	25	PF00069	0.676
MOD_PKA_2	24	30	PF00069	0.666
MOD_PKA_2	92	98	PF00069	0.686
MOD_Plk_1	13	19	PF00069	0.610
MOD_Plk_4	29	35	PF00069	0.638
MOD_Plk_4	99	105	PF00069	0.424
MOD_ProDKin_1	66	72	PF00069	0.647
MOD_ProDKin_1	83	89	PF00069	0.590
MOD_SUMO_rev_2	119	128	PF00179	0.467
MOD_SUMO_rev_2	144	152	PF00179	0.499
TRG_ER_diArg_1	1	3	PF00400	0.693
TRG_ER_diArg_1	80	83	PF00400	0.712


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IFQ1	Leishmania donovani	91%	100%
A4HCN6	Leishmania braziliensis	61%	100%
A4I061	Leishmania infantum	91%	100%
E9AW24	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%