LeishMANIAdb
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Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Protein kinase domain-containing protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania major
UniProt:
E9ACR3_LEIMA
TriTrypDb:
Length:
64

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ACR3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACR3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 31 33 PF00675 0.451
CLV_PCSK_KEX2_1 31 33 PF00082 0.451
CLV_PCSK_SKI1_1 25 29 PF00082 0.446
DEG_Nend_UBRbox_3 1 3 PF02207 0.499
LIG_14-3-3_CanoR_1 46 51 PF00244 0.407
LIG_BIR_III_4 11 15 PF00653 0.474
LIG_PDZ_Class_2 59 64 PF00595 0.386
LIG_WRC_WIRS_1 47 52 PF05994 0.404
MOD_CK2_1 30 36 PF00069 0.440
MOD_Cter_Amidation 29 32 PF01082 0.453
MOD_GSK3_1 2 9 PF00069 0.473
MOD_LATS_1 44 50 PF00433 0.405
MOD_PKA_2 2 8 PF00069 0.473
MOD_PKA_2 30 36 PF00069 0.440

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS