LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Secreted protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania major
UniProt:
E9ACQ9_LEIMA
TriTrypDb:
Length:
48

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ACQ9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACQ9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 43 45 PF00675 0.354
CLV_PCSK_SKI1_1 8 12 PF00082 0.400
DEG_Nend_Nbox_1 1 3 PF02207 0.322
DOC_CDC14_PxL_1 15 23 PF14671 0.199
DOC_PP1_RVXF_1 6 13 PF00149 0.311
DOC_PP4_FxxP_1 16 19 PF00568 0.199
LIG_14-3-3_CanoR_1 39 48 PF00244 0.548
LIG_BRCT_BRCA1_1 13 17 PF00533 0.199
LIG_LIR_Apic_2 14 19 PF02991 0.199
LIG_LIR_Nem_3 14 18 PF02991 0.199
LIG_MLH1_MIPbox_1 13 17 PF16413 0.199
LIG_Pex14_2 12 16 PF04695 0.199
LIG_SH3_3 7 13 PF00018 0.199
LIG_WRC_WIRS_1 12 17 PF05994 0.199
MOD_GSK3_1 39 46 PF00069 0.544
MOD_N-GLC_2 32 34 PF02516 0.310
MOD_Plk_4 11 17 PF00069 0.199
MOD_SUMO_rev_2 38 47 PF00179 0.544
TRG_Pf-PMV_PEXEL_1 29 33 PF00026 0.322

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS