Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

E9ACQ1_LEIMA

TriTrypDb:

LmjF.05.1225 , LMJLV39_320047900 , LMJSD75_320048200

Length:

271

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9ACQ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACQ1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	54	58	PF00656	0.569
CLV_NRD_NRD_1	136	138	PF00675	0.549
CLV_NRD_NRD_1	155	157	PF00675	0.496
CLV_NRD_NRD_1	237	239	PF00675	0.399
CLV_PCSK_FUR_1	136	140	PF00082	0.565
CLV_PCSK_KEX2_1	128	130	PF00082	0.588
CLV_PCSK_KEX2_1	136	138	PF00082	0.548
CLV_PCSK_KEX2_1	155	157	PF00082	0.474
CLV_PCSK_PC1ET2_1	128	130	PF00082	0.588
CLV_PCSK_PC1ET2_1	138	140	PF00082	0.529
CLV_PCSK_SKI1_1	155	159	PF00082	0.528
CLV_PCSK_SKI1_1	267	271	PF00082	0.464
DEG_Nend_UBRbox_1	1	4	PF02207	0.502
DOC_CKS1_1	182	187	PF01111	0.520
DOC_PP2B_LxvP_1	84	87	PF13499	0.543
DOC_USP7_MATH_1	119	123	PF00917	0.566
DOC_USP7_MATH_1	131	135	PF00917	0.553
DOC_USP7_MATH_1	144	148	PF00917	0.614
DOC_USP7_MATH_1	16	20	PF00917	0.562
DOC_USP7_MATH_1	194	198	PF00917	0.587
DOC_USP7_MATH_1	209	213	PF00917	0.368
DOC_USP7_MATH_1	3	7	PF00917	0.482
DOC_USP7_MATH_1	42	46	PF00917	0.595
DOC_USP7_MATH_1	64	68	PF00917	0.577
DOC_USP7_UBL2_3	124	128	PF12436	0.572
DOC_USP7_UBL2_3	267	271	PF12436	0.464
DOC_WW_Pin1_4	104	109	PF00397	0.556
DOC_WW_Pin1_4	18	23	PF00397	0.537
DOC_WW_Pin1_4	181	186	PF00397	0.514
DOC_WW_Pin1_4	38	43	PF00397	0.553
DOC_WW_Pin1_4	98	103	PF00397	0.573
LIG_14-3-3_CanoR_1	2	12	PF00244	0.487
LIG_14-3-3_CanoR_1	238	246	PF00244	0.410
LIG_BIR_III_2	179	183	PF00653	0.513
LIG_BIR_III_2	191	195	PF00653	0.495
LIG_deltaCOP1_diTrp_1	250	259	PF00928	0.460
LIG_EVH1_1	181	185	PF00568	0.511
LIG_FHA_1	105	111	PF00498	0.767
LIG_FHA_1	18	24	PF00498	0.743
LIG_FHA_1	259	265	PF00498	0.425
LIG_FHA_1	45	51	PF00498	0.576
LIG_FHA_1	81	87	PF00498	0.709
LIG_FHA_2	107	113	PF00498	0.696
LIG_FHA_2	182	188	PF00498	0.523
LIG_FHA_2	33	39	PF00498	0.581
LIG_LIR_Apic_2	217	223	PF02991	0.384
LIG_LIR_Apic_2	251	257	PF02991	0.471
LIG_LIR_Nem_3	146	152	PF02991	0.509
LIG_LIR_Nem_3	258	262	PF02991	0.415
LIG_SH2_GRB2like	220	223	PF00017	0.371
LIG_SH2_PTP2	220	223	PF00017	0.371
LIG_SH2_SRC	204	207	PF00017	0.438
LIG_SH2_SRC	220	223	PF00017	0.324
LIG_SH2_STAT5	220	223	PF00017	0.371
LIG_SH3_3	179	185	PF00018	0.514
LIG_SH3_3	200	206	PF00018	0.472
MOD_CDK_SPxxK_3	18	25	PF00069	0.520
MOD_CK1_1	122	128	PF00069	0.694
MOD_CK1_1	161	167	PF00069	0.588
MOD_CK1_1	41	47	PF00069	0.759
MOD_CK1_1	58	64	PF00069	0.549
MOD_CK2_1	106	112	PF00069	0.598
MOD_CK2_1	181	187	PF00069	0.520
MOD_CK2_1	194	200	PF00069	0.484
MOD_CK2_1	32	38	PF00069	0.589
MOD_CK2_1	42	48	PF00069	0.575
MOD_GlcNHglycan	130	134	PF01048	0.613
MOD_GlcNHglycan	159	163	PF01048	0.552
MOD_GlcNHglycan	230	233	PF01048	0.384
MOD_GlcNHglycan	234	237	PF01048	0.371
MOD_GlcNHglycan	96	99	PF01048	0.586
MOD_GSK3_1	228	235	PF00069	0.381
MOD_GSK3_1	237	244	PF00069	0.372
MOD_GSK3_1	38	45	PF00069	0.664
MOD_GSK3_1	51	58	PF00069	0.538
MOD_GSK3_1	94	101	PF00069	0.756
MOD_NEK2_1	158	163	PF00069	0.547
MOD_NEK2_1	228	233	PF00069	0.380
MOD_NEK2_1	4	9	PF00069	0.573
MOD_NEK2_2	131	136	PF00069	0.560
MOD_PIKK_1	237	243	PF00454	0.397
MOD_PIKK_1	64	70	PF00454	0.573
MOD_PKA_2	237	243	PF00069	0.397
MOD_PKA_2	4	10	PF00069	0.509
MOD_Plk_1	145	151	PF00069	0.540
MOD_Plk_4	145	151	PF00069	0.665
MOD_Plk_4	209	215	PF00069	0.382
MOD_ProDKin_1	18	24	PF00069	0.543
MOD_ProDKin_1	181	187	PF00069	0.520
MOD_ProDKin_1	38	44	PF00069	0.552
MOD_ProDKin_1	98	104	PF00069	0.573
TRG_DiLeu_BaEn_1	242	247	PF01217	0.415
TRG_DiLeu_BaLyEn_6	19	24	PF01217	0.548
TRG_DiLeu_LyEn_5	242	247	PF01217	0.415
TRG_ER_diArg_1	135	137	PF00400	0.554
TRG_Pf-PMV_PEXEL_1	245	250	PF00026	0.449

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E8NHN4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	83%