Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

E9ACP9_LEIMA

TriTrypDb:

LmjF.04.0975 , LMJLV39_040015400 , LMJSD75_040015700

Length:

497

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ACP9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACP9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	184	188	PF00656	0.583
CLV_NRD_NRD_1	115	117	PF00675	0.548
CLV_NRD_NRD_1	34	36	PF00675	0.524
CLV_NRD_NRD_1	62	64	PF00675	0.706
CLV_NRD_NRD_1	72	74	PF00675	0.625
CLV_PCSK_FUR_1	32	36	PF00082	0.524
CLV_PCSK_KEX2_1	115	117	PF00082	0.548
CLV_PCSK_KEX2_1	34	36	PF00082	0.524
CLV_PCSK_KEX2_1	61	63	PF00082	0.695
CLV_PCSK_PC7_1	30	36	PF00082	0.523
CLV_PCSK_SKI1_1	116	120	PF00082	0.545
CLV_PCSK_SKI1_1	428	432	PF00082	0.507
DEG_SPOP_SBC_1	137	141	PF00917	0.668
DOC_CYCLIN_yCln2_LP_2	119	122	PF00134	0.710
DOC_CYCLIN_yCln2_LP_2	238	244	PF00134	0.553
DOC_MAPK_DCC_7	115	125	PF00069	0.685
DOC_MAPK_MEF2A_6	116	125	PF00069	0.562
DOC_PP2B_LxvP_1	119	122	PF13499	0.690
DOC_PP2B_LxvP_1	238	241	PF13499	0.559
DOC_PP2B_LxvP_1	46	49	PF13499	0.632
DOC_PP4_MxPP_1	467	470	PF00568	0.542
DOC_USP7_MATH_1	100	104	PF00917	0.639
DOC_USP7_MATH_1	105	109	PF00917	0.609
DOC_USP7_MATH_1	124	128	PF00917	0.527
DOC_USP7_MATH_1	217	221	PF00917	0.601
DOC_USP7_MATH_1	250	254	PF00917	0.685
DOC_USP7_MATH_1	282	286	PF00917	0.655
DOC_USP7_MATH_1	337	341	PF00917	0.614
DOC_USP7_MATH_1	386	390	PF00917	0.796
DOC_USP7_MATH_1	49	53	PF00917	0.566
DOC_WW_Pin1_4	191	196	PF00397	0.678
DOC_WW_Pin1_4	225	230	PF00397	0.610
DOC_WW_Pin1_4	236	241	PF00397	0.647
DOC_WW_Pin1_4	251	256	PF00397	0.740
DOC_WW_Pin1_4	344	349	PF00397	0.790
DOC_WW_Pin1_4	36	41	PF00397	0.510
DOC_WW_Pin1_4	390	395	PF00397	0.748
DOC_WW_Pin1_4	404	409	PF00397	0.556
DOC_WW_Pin1_4	459	464	PF00397	0.702
DOC_WW_Pin1_4	482	487	PF00397	0.617
DOC_WW_Pin1_4	94	99	PF00397	0.631
LIG_14-3-3_CanoR_1	314	320	PF00244	0.588
LIG_14-3-3_CanoR_1	428	433	PF00244	0.573
LIG_Actin_WH2_2	412	430	PF00022	0.495
LIG_APCC_ABBAyCdc20_2	10	16	PF00400	0.464
LIG_BIR_II_1	1	5	PF00653	0.590
LIG_EVH1_2	121	125	PF00568	0.622
LIG_FHA_1	175	181	PF00498	0.686
LIG_FHA_1	370	376	PF00498	0.533
LIG_FHA_1	476	482	PF00498	0.564
LIG_FHA_2	138	144	PF00498	0.669
LIG_FHA_2	165	171	PF00498	0.632
LIG_FHA_2	352	358	PF00498	0.636
LIG_FHA_2	416	422	PF00498	0.572
LIG_LIR_Apic_2	464	469	PF02991	0.641
LIG_LIR_Nem_3	131	136	PF02991	0.729
LIG_LIR_Nem_3	147	153	PF02991	0.502
LIG_MYND_1	342	346	PF01753	0.559
LIG_NRBOX	422	428	PF00104	0.454
LIG_Pex14_1	7	11	PF04695	0.457
LIG_SH2_STAT5	136	139	PF00017	0.669
LIG_SH2_STAT5	8	11	PF00017	0.483
LIG_SH3_1	61	67	PF00018	0.617
LIG_SH3_2	197	202	PF14604	0.541
LIG_SH3_2	57	62	PF14604	0.716
LIG_SH3_3	115	121	PF00018	0.587
LIG_SH3_3	146	152	PF00018	0.616
LIG_SH3_3	193	199	PF00018	0.762
LIG_SH3_3	224	230	PF00018	0.594
LIG_SH3_3	237	243	PF00018	0.585
LIG_SH3_3	246	252	PF00018	0.706
LIG_SH3_3	295	301	PF00018	0.537
LIG_SH3_3	340	346	PF00018	0.745
LIG_SH3_3	37	43	PF00018	0.499
LIG_SH3_3	391	397	PF00018	0.724
LIG_SH3_3	434	440	PF00018	0.532
LIG_SH3_3	52	58	PF00018	0.710
LIG_SH3_3	61	67	PF00018	0.630
LIG_TRAF2_1	365	368	PF00917	0.583
LIG_WW_3	39	43	PF00397	0.525
LIG_WW_3	58	62	PF00397	0.509
LIG_WW_3	70	74	PF00397	0.501
MOD_CDK_SPxK_1	36	42	PF00069	0.521
MOD_CK1_1	138	144	PF00069	0.678
MOD_CK1_1	228	234	PF00069	0.562
MOD_CK1_1	254	260	PF00069	0.545
MOD_CK1_1	389	395	PF00069	0.796
MOD_CK2_1	282	288	PF00069	0.605
MOD_CK2_1	351	357	PF00069	0.593
MOD_CK2_1	415	421	PF00069	0.545
MOD_GlcNHglycan	126	129	PF01048	0.559
MOD_GlcNHglycan	213	216	PF01048	0.630
MOD_GlcNHglycan	244	247	PF01048	0.551
MOD_GlcNHglycan	284	287	PF01048	0.640
MOD_GlcNHglycan	388	391	PF01048	0.772
MOD_GSK3_1	181	188	PF00069	0.581
MOD_GSK3_1	250	257	PF00069	0.614
MOD_GSK3_1	353	360	PF00069	0.762
MOD_GSK3_1	386	393	PF00069	0.763
MOD_GSK3_1	395	402	PF00069	0.714
MOD_GSK3_1	457	464	PF00069	0.612
MOD_N-GLC_1	428	433	PF02516	0.562
MOD_NEK2_1	1	6	PF00069	0.612
MOD_NEK2_1	111	116	PF00069	0.665
MOD_PIKK_1	308	314	PF00454	0.733
MOD_PIKK_1	475	481	PF00454	0.509
MOD_Plk_1	100	106	PF00069	0.627
MOD_Plk_1	337	343	PF00069	0.671
MOD_Plk_1	428	434	PF00069	0.442
MOD_Plk_2-3	415	421	PF00069	0.545
MOD_Plk_4	185	191	PF00069	0.550
MOD_Plk_4	228	234	PF00069	0.558
MOD_Plk_4	23	29	PF00069	0.593
MOD_Plk_4	462	468	PF00069	0.528
MOD_ProDKin_1	191	197	PF00069	0.679
MOD_ProDKin_1	225	231	PF00069	0.613
MOD_ProDKin_1	236	242	PF00069	0.643
MOD_ProDKin_1	251	257	PF00069	0.540
MOD_ProDKin_1	344	350	PF00069	0.793
MOD_ProDKin_1	36	42	PF00069	0.519
MOD_ProDKin_1	390	396	PF00069	0.747
MOD_ProDKin_1	404	410	PF00069	0.555
MOD_ProDKin_1	459	465	PF00069	0.700
MOD_ProDKin_1	482	488	PF00069	0.618
MOD_ProDKin_1	94	100	PF00069	0.629
MOD_SUMO_for_1	365	368	PF00179	0.550
TRG_DiLeu_BaLyEn_6	340	345	PF01217	0.558
TRG_ER_diArg_1	29	32	PF00400	0.496
TRG_ER_diArg_1	436	439	PF00400	0.535
TRG_ER_diArg_1	60	63	PF00400	0.647
TRG_ER_diArg_1	77	80	PF00400	0.735

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0B3	Leptomonas seymouri	29%	100%
A0A3S5H5D9	Leishmania donovani	85%	100%
A4H412	Leishmania braziliensis	62%	100%
A4HS95	Leishmania infantum	85%	100%
E9AK79	Leishmania mexicana (strain MHOM/GT/2001/U1103)	71%	100%