Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

E9ACP4_LEIMA

TriTrypDb:

LmjF.04.0035 , LMJLV39_040005300 , LMJSD75_040005300

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

E9ACP4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACP4


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	28	30	PF00675	0.390
CLV_NRD_NRD_1	35	37	PF00675	0.400
DOC_MAPK_gen_1	36	43	PF00069	0.596
DOC_SPAK_OSR1_1	51	55	PF12202	0.550
DOC_USP7_MATH_1	16	20	PF00917	0.305
DOC_USP7_MATH_1	68	72	PF00917	0.634
LIG_14-3-3_CanoR_1	36	43	PF00244	0.635
LIG_14-3-3_CterR_2	69	73	PF00244	0.679
LIG_FHA_1	36	42	PF00498	0.585
LIG_FHA_2	59	65	PF00498	0.628
LIG_SH2_CRK	25	29	PF00017	0.583
LIG_TYR_ITIM	23	28	PF00017	0.621
MOD_CK2_1	58	64	PF00069	0.592
MOD_GlcNHglycan	18	21	PF01048	0.297
MOD_GlcNHglycan	70	73	PF01048	0.549
MOD_GSK3_1	12	19	PF00069	0.321
MOD_GSK3_1	31	38	PF00069	0.597
MOD_PKA_2	35	41	PF00069	0.638
TRG_ENDOCYTIC_2	25	28	PF00928	0.595
TRG_Pf-PMV_PEXEL_1	60	64	PF00026	0.438


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4C0	Leptomonas seymouri	64%	88%
A0A3S5H572	Leishmania donovani	92%	100%
E9AG59	Leishmania infantum	92%	100%
E9AI21	Leishmania braziliensis	88%	100%
E9AJY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%