Uncharacterized protein

hypothetical protein, conserved

Leishmania major

435

Source | Evidence on protein | Close homologs |
---|---|---|

Cuervo et al. | no | yes: 0 |

Hassani et al. | no | yes: 0 |

Forrest at al. (metacyclic) | no | yes: 0 |

Forrest at al. (procyclic) | no | yes: 0 |

Silverman et al. | no | yes: 0 |

Pissara et al. | no | yes: 0 |

Source | Evidence on protein | Close homologs |
---|---|---|

Pires et al. | no | yes: 0 |

Source | Evidence on protein | Close homologs |
---|---|---|

Silverman et al. | no | yes: 0 |

Source | Evidence on protein | Close homologs |
---|---|---|

Jamdhade et al. | no | yes: 0 |

Source | Evidence on protein | Close homologs |
---|---|---|

DeepLoc | ||

SignalP6 | no | yes: 0, no: 6 |

NetGPI | no | yes: 0, no: 6 |

Term | Name | Level | Count |
---|---|---|---|

GO:0005654 | nucleoplasm | 2 | 2 |

GO:0110165 | cellular anatomical entity | 1 | 2 |

E9ACM4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACM4

Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|

CLV_C14_Caspase3-7 | 190 | 194 | PF00656 | 0.578 |

CLV_C14_Caspase3-7 | 289 | 293 | PF00656 | 0.700 |

CLV_NRD_NRD_1 | 22 | 24 | PF00675 | 0.630 |

CLV_NRD_NRD_1 | 241 | 243 | PF00675 | 0.518 |

CLV_NRD_NRD_1 | 250 | 252 | PF00675 | 0.559 |

CLV_PCSK_FUR_1 | 20 | 24 | PF00082 | 0.633 |

CLV_PCSK_KEX2_1 | 20 | 22 | PF00082 | 0.601 |

CLV_PCSK_KEX2_1 | 241 | 243 | PF00082 | 0.518 |

CLV_PCSK_KEX2_1 | 249 | 251 | PF00082 | 0.570 |

CLV_PCSK_SKI1_1 | 382 | 386 | PF00082 | 0.577 |

DEG_Nend_UBRbox_3 | 1 | 3 | PF02207 | 0.711 |

DOC_CKS1_1 | 330 | 335 | PF01111 | 0.730 |

DOC_CYCLIN_RxL_1 | 379 | 389 | PF00134 | 0.665 |

DOC_CYCLIN_yClb3_PxF_3 | 261 | 267 | PF00134 | 0.560 |

DOC_CYCLIN_yCln2_LP_2 | 330 | 336 | PF00134 | 0.689 |

DOC_PP2B_LxvP_1 | 252 | 255 | PF13499 | 0.655 |

DOC_PP2B_LxvP_1 | 259 | 262 | PF13499 | 0.670 |

DOC_USP7_MATH_1 | 103 | 107 | PF00917 | 0.520 |

DOC_USP7_MATH_1 | 112 | 116 | PF00917 | 0.578 |

DOC_USP7_MATH_1 | 133 | 137 | PF00917 | 0.592 |

DOC_USP7_MATH_1 | 187 | 191 | PF00917 | 0.712 |

DOC_USP7_MATH_1 | 307 | 311 | PF00917 | 0.839 |

DOC_USP7_MATH_1 | 360 | 364 | PF00917 | 0.745 |

DOC_USP7_MATH_1 | 380 | 384 | PF00917 | 0.639 |

DOC_USP7_MATH_1 | 65 | 69 | PF00917 | 0.646 |

DOC_USP7_MATH_1 | 95 | 99 | PF00917 | 0.704 |

DOC_WW_Pin1_4 | 110 | 115 | PF00397 | 0.628 |

DOC_WW_Pin1_4 | 143 | 148 | PF00397 | 0.702 |

DOC_WW_Pin1_4 | 153 | 158 | PF00397 | 0.696 |

DOC_WW_Pin1_4 | 261 | 266 | PF00397 | 0.712 |

DOC_WW_Pin1_4 | 329 | 334 | PF00397 | 0.740 |

DOC_WW_Pin1_4 | 336 | 341 | PF00397 | 0.650 |

DOC_WW_Pin1_4 | 364 | 369 | PF00397 | 0.670 |

DOC_WW_Pin1_4 | 5 | 10 | PF00397 | 0.639 |

LIG_14-3-3_CanoR_1 | 151 | 160 | PF00244 | 0.656 |

LIG_14-3-3_CanoR_1 | 382 | 391 | PF00244 | 0.626 |

LIG_14-3-3_CanoR_1 | 72 | 77 | PF00244 | 0.720 |

LIG_BIR_III_4 | 318 | 322 | PF00653 | 0.816 |

LIG_BRCT_BRCA1_1 | 263 | 267 | PF00533 | 0.549 |

LIG_CSL_BTD_1 | 252 | 255 | PF09270 | 0.553 |

LIG_FHA_1 | 105 | 111 | PF00498 | 0.544 |

LIG_FHA_1 | 330 | 336 | PF00498 | 0.805 |

LIG_FHA_2 | 154 | 160 | PF00498 | 0.590 |

LIG_FHA_2 | 313 | 319 | PF00498 | 0.772 |

LIG_FHA_2 | 9 | 15 | PF00498 | 0.583 |

LIG_LIR_Apic_2 | 257 | 263 | PF02991 | 0.548 |

LIG_LIR_Gen_1 | 164 | 171 | PF02991 | 0.791 |

LIG_LIR_Gen_1 | 198 | 209 | PF02991 | 0.522 |

LIG_LIR_Gen_1 | 223 | 231 | PF02991 | 0.537 |

LIG_LIR_LC3C_4 | 116 | 121 | PF02991 | 0.676 |

LIG_LIR_Nem_3 | 14 | 19 | PF02991 | 0.612 |

LIG_LIR_Nem_3 | 164 | 170 | PF02991 | 0.789 |

LIG_LIR_Nem_3 | 198 | 204 | PF02991 | 0.528 |

LIG_LIR_Nem_3 | 223 | 228 | PF02991 | 0.541 |

LIG_LIR_Nem_3 | 403 | 408 | PF02991 | 0.514 |

LIG_NRBOX | 118 | 124 | PF00104 | 0.677 |

LIG_PCNA_yPIPBox_3 | 12 | 26 | PF02747 | 0.608 |

LIG_PTAP_UEV_1 | 60 | 65 | PF05743 | 0.553 |

LIG_SH2_CRK | 16 | 20 | PF00017 | 0.592 |

LIG_SH2_CRK | 167 | 171 | PF00017 | 0.796 |

LIG_SH2_CRK | 201 | 205 | PF00017 | 0.544 |

LIG_SH2_STAP1 | 201 | 205 | PF00017 | 0.522 |

LIG_SH2_STAT3 | 371 | 374 | PF00017 | 0.750 |

LIG_SH2_STAT5 | 131 | 134 | PF00017 | 0.557 |

LIG_SH3_1 | 260 | 266 | PF00018 | 0.635 |

LIG_SH3_3 | 157 | 163 | PF00018 | 0.598 |

LIG_SH3_3 | 259 | 265 | PF00018 | 0.754 |

LIG_SH3_3 | 392 | 398 | PF00018 | 0.515 |

LIG_SH3_3 | 58 | 64 | PF00018 | 0.633 |

LIG_SUMO_SIM_par_1 | 118 | 125 | PF11976 | 0.567 |

LIG_SUMO_SIM_par_1 | 332 | 337 | PF11976 | 0.691 |

LIG_TRFH_1 | 34 | 38 | PF08558 | 0.691 |

MOD_CDK_SPK_2 | 153 | 158 | PF00069 | 0.696 |

MOD_CK1_1 | 106 | 112 | PF00069 | 0.552 |

MOD_CK1_1 | 113 | 119 | PF00069 | 0.526 |

MOD_CK1_1 | 275 | 281 | PF00069 | 0.789 |

MOD_CK1_1 | 367 | 373 | PF00069 | 0.640 |

MOD_CK1_1 | 383 | 389 | PF00069 | 0.380 |

MOD_CK1_1 | 5 | 11 | PF00069 | 0.631 |

MOD_CK1_1 | 68 | 74 | PF00069 | 0.711 |

MOD_CK1_1 | 75 | 81 | PF00069 | 0.796 |

MOD_CK1_1 | 98 | 104 | PF00069 | 0.663 |

MOD_CK2_1 | 383 | 389 | PF00069 | 0.626 |

MOD_CK2_1 | 8 | 14 | PF00069 | 0.616 |

MOD_GlcNHglycan | 141 | 144 | PF01048 | 0.635 |

MOD_GlcNHglycan | 183 | 186 | PF01048 | 0.667 |

MOD_GlcNHglycan | 277 | 280 | PF01048 | 0.770 |

MOD_GlcNHglycan | 309 | 312 | PF01048 | 0.765 |

MOD_GlcNHglycan | 61 | 64 | PF01048 | 0.630 |

MOD_GlcNHglycan | 65 | 68 | PF01048 | 0.632 |

MOD_GlcNHglycan | 85 | 88 | PF01048 | 0.674 |

MOD_GlcNHglycan | 97 | 100 | PF01048 | 0.554 |

MOD_GSK3_1 | 106 | 113 | PF00069 | 0.594 |

MOD_GSK3_1 | 139 | 146 | PF00069 | 0.670 |

MOD_GSK3_1 | 170 | 177 | PF00069 | 0.731 |

MOD_GSK3_1 | 183 | 190 | PF00069 | 0.656 |

MOD_GSK3_1 | 266 | 273 | PF00069 | 0.798 |

MOD_GSK3_1 | 325 | 332 | PF00069 | 0.818 |

MOD_GSK3_1 | 360 | 367 | PF00069 | 0.699 |

MOD_GSK3_1 | 59 | 66 | PF00069 | 0.650 |

MOD_GSK3_1 | 68 | 75 | PF00069 | 0.686 |

MOD_N-GLC_1 | 133 | 138 | PF02516 | 0.704 |

MOD_N-GLC_1 | 275 | 280 | PF02516 | 0.789 |

MOD_N-GLC_1 | 325 | 330 | PF02516 | 0.821 |

MOD_NEK2_1 | 139 | 144 | PF00069 | 0.687 |

MOD_NEK2_1 | 196 | 201 | PF00069 | 0.618 |

MOD_NEK2_1 | 267 | 272 | PF00069 | 0.702 |

MOD_NEK2_1 | 40 | 45 | PF00069 | 0.658 |

MOD_PIKK_1 | 299 | 305 | PF00454 | 0.772 |

MOD_PK_1 | 72 | 78 | PF00069 | 0.722 |

MOD_PKA_2 | 299 | 305 | PF00069 | 0.823 |

MOD_PKA_2 | 307 | 313 | PF00069 | 0.727 |

MOD_Plk_1 | 124 | 130 | PF00069 | 0.549 |

MOD_Plk_1 | 133 | 139 | PF00069 | 0.602 |

MOD_Plk_1 | 325 | 331 | PF00069 | 0.742 |

MOD_Plk_4 | 106 | 112 | PF00069 | 0.592 |

MOD_Plk_4 | 124 | 130 | PF00069 | 0.619 |

MOD_Plk_4 | 134 | 140 | PF00069 | 0.617 |

MOD_Plk_4 | 162 | 168 | PF00069 | 0.675 |

MOD_Plk_4 | 187 | 193 | PF00069 | 0.583 |

MOD_Plk_4 | 72 | 78 | PF00069 | 0.757 |

MOD_ProDKin_1 | 110 | 116 | PF00069 | 0.619 |

MOD_ProDKin_1 | 143 | 149 | PF00069 | 0.701 |

MOD_ProDKin_1 | 153 | 159 | PF00069 | 0.696 |

MOD_ProDKin_1 | 261 | 267 | PF00069 | 0.717 |

MOD_ProDKin_1 | 329 | 335 | PF00069 | 0.739 |

MOD_ProDKin_1 | 336 | 342 | PF00069 | 0.652 |

MOD_ProDKin_1 | 364 | 370 | PF00069 | 0.664 |

MOD_ProDKin_1 | 5 | 11 | PF00069 | 0.631 |

MOD_SUMO_for_1 | 281 | 284 | PF00179 | 0.818 |

TRG_DiLeu_BaEn_1 | 14 | 19 | PF01217 | 0.630 |

TRG_DiLeu_BaEn_1 | 389 | 394 | PF01217 | 0.609 |

TRG_DiLeu_BaLyEn_6 | 330 | 335 | PF01217 | 0.706 |

TRG_DiLeu_BaLyEn_6 | 403 | 408 | PF01217 | 0.514 |

TRG_ENDOCYTIC_2 | 16 | 19 | PF00928 | 0.593 |

TRG_ENDOCYTIC_2 | 167 | 170 | PF00928 | 0.794 |

TRG_ENDOCYTIC_2 | 201 | 204 | PF00928 | 0.501 |

TRG_ENDOCYTIC_2 | 405 | 408 | PF00928 | 0.523 |

TRG_ER_diArg_1 | 150 | 153 | PF00400 | 0.677 |

TRG_ER_diArg_1 | 19 | 22 | PF00400 | 0.633 |

TRG_ER_diArg_1 | 240 | 242 | PF00400 | 0.519 |

TRG_ER_diArg_1 | 248 | 251 | PF00400 | 0.565 |

TRG_Pf-PMV_PEXEL_1 | 382 | 387 | PF00026 | 0.641 |

TRG_Pf-PMV_PEXEL_1 | 406 | 410 | PF00026 | 0.536 |

Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|

A0A0N0P3J3 | Leptomonas seymouri | 47% | 95% |

A0A3S5H559 | Leishmania donovani | 94% | 100% |

A4H3P0 | Leishmania braziliensis | 73% | 97% |

A4HRW7 | Leishmania infantum | 94% | 100% |

E9AJW2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 81% | 98% |