Putative DNA repair helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA repair helicase, putative

Species:

Leishmania major

UniProt:

E9ACK4_LEIMA

TriTrypDb:

LmjF.03.0590 , LMJLV39_030011200 , LMJSD75_030011200 , LMJSD75_030011300

Length:

1359

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005654	nucleoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9ACK4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	6
GO:0006725	cellular aromatic compound metabolic process	3	6
GO:0006807	nitrogen compound metabolic process	2	6
GO:0006996	organelle organization	4	2
GO:0008152	metabolic process	1	6
GO:0009987	cellular process	1	6
GO:0016043	cellular component organization	3	2
GO:0022402	cell cycle process	2	2
GO:0032392	DNA geometric change	7	2
GO:0032508	DNA duplex unwinding	8	2
GO:0034085	establishment of sister chromatid cohesion	3	2
GO:0034641	cellular nitrogen compound metabolic process	3	6
GO:0044237	cellular metabolic process	2	6
GO:0044238	primary metabolic process	2	6
GO:0046483	heterocycle metabolic process	3	6
GO:0051276	chromosome organization	5	2
GO:0071103	DNA conformation change	6	2
GO:0071704	organic substance metabolic process	2	6
GO:0071840	cellular component organization or biogenesis	2	2
GO:1901360	organic cyclic compound metabolic process	3	6

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003676	nucleic acid binding	3	7
GO:0003677	DNA binding	4	7
GO:0003678	DNA helicase activity	3	7
GO:0003824	catalytic activity	1	7
GO:0004386	helicase activity	2	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0008094	ATP-dependent activity, acting on DNA	2	7
GO:0016787	hydrolase activity	2	7
GO:0016817	hydrolase activity, acting on acid anhydrides	3	7
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	7
GO:0017076	purine nucleotide binding	4	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:0140657	ATP-dependent activity	1	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1086	1090	PF00656	0.449
CLV_C14_Caspase3-7	1319	1323	PF00656	0.549
CLV_C14_Caspase3-7	636	640	PF00656	0.535
CLV_C14_Caspase3-7	747	751	PF00656	0.737
CLV_C14_Caspase3-7	789	793	PF00656	0.560
CLV_NRD_NRD_1	1193	1195	PF00675	0.294
CLV_NRD_NRD_1	1255	1257	PF00675	0.399
CLV_NRD_NRD_1	1325	1327	PF00675	0.337
CLV_NRD_NRD_1	183	185	PF00675	0.535
CLV_NRD_NRD_1	219	221	PF00675	0.628
CLV_NRD_NRD_1	278	280	PF00675	0.754
CLV_NRD_NRD_1	298	300	PF00675	0.409
CLV_NRD_NRD_1	328	330	PF00675	0.722
CLV_NRD_NRD_1	387	389	PF00675	0.468
CLV_NRD_NRD_1	422	424	PF00675	0.416
CLV_NRD_NRD_1	515	517	PF00675	0.538
CLV_NRD_NRD_1	528	530	PF00675	0.634
CLV_NRD_NRD_1	599	601	PF00675	0.480
CLV_NRD_NRD_1	78	80	PF00675	0.622
CLV_NRD_NRD_1	782	784	PF00675	0.601
CLV_NRD_NRD_1	81	83	PF00675	0.615
CLV_NRD_NRD_1	89	91	PF00675	0.591
CLV_NRD_NRD_1	95	97	PF00675	0.585
CLV_PCSK_FUR_1	420	424	PF00082	0.416
CLV_PCSK_FUR_1	526	530	PF00082	0.739
CLV_PCSK_FUR_1	780	784	PF00082	0.595
CLV_PCSK_FUR_1	79	83	PF00082	0.693
CLV_PCSK_KEX2_1	1108	1110	PF00082	0.388
CLV_PCSK_KEX2_1	1193	1195	PF00082	0.294
CLV_PCSK_KEX2_1	1255	1257	PF00082	0.383
CLV_PCSK_KEX2_1	1324	1326	PF00082	0.337
CLV_PCSK_KEX2_1	278	280	PF00082	0.754
CLV_PCSK_KEX2_1	298	300	PF00082	0.409
CLV_PCSK_KEX2_1	328	330	PF00082	0.722
CLV_PCSK_KEX2_1	387	389	PF00082	0.468
CLV_PCSK_KEX2_1	422	424	PF00082	0.355
CLV_PCSK_KEX2_1	515	517	PF00082	0.538
CLV_PCSK_KEX2_1	526	528	PF00082	0.648
CLV_PCSK_KEX2_1	599	601	PF00082	0.480
CLV_PCSK_KEX2_1	760	762	PF00082	0.606
CLV_PCSK_KEX2_1	78	80	PF00082	0.622
CLV_PCSK_KEX2_1	782	784	PF00082	0.605
CLV_PCSK_KEX2_1	81	83	PF00082	0.615
CLV_PCSK_KEX2_1	89	91	PF00082	0.591
CLV_PCSK_PC1ET2_1	1108	1110	PF00082	0.388
CLV_PCSK_PC1ET2_1	760	762	PF00082	0.606
CLV_PCSK_PC7_1	1320	1326	PF00082	0.337
CLV_PCSK_PC7_1	383	389	PF00082	0.460
CLV_PCSK_SKI1_1	1108	1112	PF00082	0.316
CLV_PCSK_SKI1_1	1194	1198	PF00082	0.294
CLV_PCSK_SKI1_1	1349	1353	PF00082	0.503
CLV_PCSK_SKI1_1	207	211	PF00082	0.598
CLV_PCSK_SKI1_1	278	282	PF00082	0.739
CLV_PCSK_SKI1_1	437	441	PF00082	0.420
CLV_PCSK_SKI1_1	459	463	PF00082	0.346
CLV_PCSK_SKI1_1	49	53	PF00082	0.638
CLV_PCSK_SKI1_1	599	603	PF00082	0.488
CLV_PCSK_SKI1_1	612	616	PF00082	0.405
CLV_PCSK_SKI1_1	782	786	PF00082	0.655
CLV_PCSK_SKI1_1	842	846	PF00082	0.564
CLV_Separin_Metazoa	1145	1149	PF03568	0.583
CLV_Separin_Metazoa	63	67	PF03568	0.703
DEG_APCC_DBOX_1	1235	1243	PF00400	0.449
DEG_APCC_DBOX_1	781	789	PF00400	0.588
DEG_Nend_Nbox_1	1	3	PF02207	0.392
DEG_SCF_FBW7_1	479	486	PF00400	0.619
DEG_SPOP_SBC_1	1001	1005	PF00917	0.505
DEG_SPOP_SBC_1	1033	1037	PF00917	0.594
DEG_SPOP_SBC_1	1170	1174	PF00917	0.549
DEG_SPOP_SBC_1	1270	1274	PF00917	0.561
DEG_SPOP_SBC_1	246	250	PF00917	0.581
DEG_SPOP_SBC_1	671	675	PF00917	0.695
DOC_ANK_TNKS_1	230	237	PF00023	0.552
DOC_CKS1_1	480	485	PF01111	0.665
DOC_CKS1_1	870	875	PF01111	0.624
DOC_CYCLIN_RxL_1	434	444	PF00134	0.614
DOC_CYCLIN_RxL_1	594	604	PF00134	0.484
DOC_CYCLIN_RxL_1	678	689	PF00134	0.401
DOC_CYCLIN_RxL_1	779	789	PF00134	0.583
DOC_MAPK_gen_1	134	143	PF00069	0.446
DOC_MAPK_gen_1	184	190	PF00069	0.557
DOC_MAPK_gen_1	278	285	PF00069	0.711
DOC_MAPK_gen_1	618	627	PF00069	0.459
DOC_MAPK_gen_1	760	769	PF00069	0.713
DOC_MAPK_gen_1	780	790	PF00069	0.593
DOC_MAPK_gen_1	93	101	PF00069	0.695
DOC_MAPK_MEF2A_6	1218	1225	PF00069	0.546
DOC_MAPK_MEF2A_6	763	771	PF00069	0.658
DOC_MAPK_MEF2A_6	956	963	PF00069	0.566
DOC_PP1_RVXF_1	185	191	PF00149	0.552
DOC_PP1_RVXF_1	866	872	PF00149	0.537
DOC_PP2B_LxvP_1	1223	1226	PF13499	0.583
DOC_PP2B_LxvP_1	658	661	PF13499	0.608
DOC_PP2B_LxvP_1	683	686	PF13499	0.332
DOC_PP2B_LxvP_1	788	791	PF13499	0.650
DOC_PP4_FxxP_1	480	483	PF00568	0.669
DOC_USP7_MATH_1	1002	1006	PF00917	0.336
DOC_USP7_MATH_1	1034	1038	PF00917	0.638
DOC_USP7_MATH_1	1168	1172	PF00917	0.553
DOC_USP7_MATH_1	1182	1186	PF00917	0.609
DOC_USP7_MATH_1	1270	1274	PF00917	0.559
DOC_USP7_MATH_1	224	228	PF00917	0.720
DOC_USP7_MATH_1	24	28	PF00917	0.680
DOC_USP7_MATH_1	246	250	PF00917	0.616
DOC_USP7_MATH_1	263	267	PF00917	0.799
DOC_USP7_MATH_1	268	272	PF00917	0.776
DOC_USP7_MATH_1	40	44	PF00917	0.607
DOC_USP7_MATH_1	403	407	PF00917	0.710
DOC_USP7_MATH_1	481	485	PF00917	0.710
DOC_USP7_MATH_1	669	673	PF00917	0.722
DOC_USP7_MATH_1	987	991	PF00917	0.578
DOC_USP7_UBL2_3	1108	1112	PF12436	0.583
DOC_WW_Pin1_4	1049	1054	PF00397	0.462
DOC_WW_Pin1_4	1174	1179	PF00397	0.491
DOC_WW_Pin1_4	1264	1269	PF00397	0.557
DOC_WW_Pin1_4	1271	1276	PF00397	0.506
DOC_WW_Pin1_4	252	257	PF00397	0.779
DOC_WW_Pin1_4	266	271	PF00397	0.658
DOC_WW_Pin1_4	479	484	PF00397	0.703
DOC_WW_Pin1_4	501	506	PF00397	0.651
DOC_WW_Pin1_4	52	57	PF00397	0.702
DOC_WW_Pin1_4	659	664	PF00397	0.698
DOC_WW_Pin1_4	672	677	PF00397	0.545
DOC_WW_Pin1_4	869	874	PF00397	0.599
DOC_WW_Pin1_4	877	882	PF00397	0.556
LIG_14-3-3_CanoR_1	1044	1053	PF00244	0.566
LIG_14-3-3_CanoR_1	1205	1212	PF00244	0.503
LIG_14-3-3_CanoR_1	1324	1333	PF00244	0.537
LIG_14-3-3_CanoR_1	1336	1342	PF00244	0.473
LIG_14-3-3_CanoR_1	193	202	PF00244	0.591
LIG_14-3-3_CanoR_1	278	285	PF00244	0.663
LIG_14-3-3_CanoR_1	376	382	PF00244	0.574
LIG_14-3-3_CanoR_1	516	525	PF00244	0.569
LIG_14-3-3_CanoR_1	583	589	PF00244	0.526
LIG_14-3-3_CanoR_1	741	747	PF00244	0.537
LIG_14-3-3_CanoR_1	783	789	PF00244	0.607
LIG_14-3-3_CanoR_1	842	849	PF00244	0.545
LIG_APCC_ABBA_1	569	574	PF00400	0.503
LIG_APCC_ABBAyCdc20_2	313	319	PF00400	0.585
LIG_BIR_III_4	353	357	PF00653	0.642
LIG_BIR_III_4	943	947	PF00653	0.506
LIG_BRCT_BRCA1_1	1272	1276	PF00533	0.557
LIG_BRCT_BRCA1_1	7	11	PF00533	0.498
LIG_CSL_BTD_1	870	873	PF09270	0.662
LIG_CtBP_PxDLS_1	505	509	PF00389	0.639
LIG_eIF4E_1	1307	1313	PF01652	0.537
LIG_eIF4E_1	433	439	PF01652	0.614
LIG_eIF4E_1	904	910	PF01652	0.493
LIG_FAT_LD_1	852	860	PF03623	0.431
LIG_FHA_1	1307	1313	PF00498	0.583
LIG_FHA_1	391	397	PF00498	0.521
LIG_FHA_1	434	440	PF00498	0.546
LIG_FHA_1	583	589	PF00498	0.483
LIG_FHA_1	680	686	PF00498	0.531
LIG_FHA_1	704	710	PF00498	0.525
LIG_FHA_1	741	747	PF00498	0.658
LIG_FHA_1	754	760	PF00498	0.542
LIG_FHA_1	865	871	PF00498	0.518
LIG_FHA_2	1034	1040	PF00498	0.564
LIG_FHA_2	1081	1087	PF00498	0.583
LIG_FHA_2	1229	1235	PF00498	0.495
LIG_FHA_2	1275	1281	PF00498	0.583
LIG_FHA_2	230	236	PF00498	0.735
LIG_FHA_2	470	476	PF00498	0.569
LIG_FHA_2	58	64	PF00498	0.634
LIG_GBD_Chelix_1	809	817	PF00786	0.643
LIG_Integrin_RGD_1	136	138	PF01839	0.635
LIG_LIR_Apic_2	1328	1333	PF02991	0.537
LIG_LIR_Apic_2	53	57	PF02991	0.517
LIG_LIR_Gen_1	1083	1093	PF02991	0.540
LIG_LIR_Gen_1	1098	1107	PF02991	0.494
LIG_LIR_Gen_1	1306	1315	PF02991	0.537
LIG_LIR_Gen_1	208	217	PF02991	0.657
LIG_LIR_Gen_1	551	562	PF02991	0.571
LIG_LIR_Gen_1	700	709	PF02991	0.425
LIG_LIR_Gen_1	990	1000	PF02991	0.564
LIG_LIR_Nem_3	1098	1104	PF02991	0.537
LIG_LIR_Nem_3	1280	1285	PF02991	0.537
LIG_LIR_Nem_3	1306	1310	PF02991	0.537
LIG_LIR_Nem_3	208	213	PF02991	0.591
LIG_LIR_Nem_3	444	450	PF02991	0.546
LIG_LIR_Nem_3	700	705	PF02991	0.425
LIG_LIR_Nem_3	8	14	PF02991	0.515
LIG_LIR_Nem_3	905	909	PF02991	0.437
LIG_LIR_Nem_3	990	995	PF02991	0.519
LIG_Pex14_2	1341	1345	PF04695	0.472
LIG_Rb_LxCxE_1	845	867	PF01857	0.507
LIG_Rb_pABgroove_1	5	13	PF01858	0.550
LIG_REV1ctd_RIR_1	1349	1356	PF16727	0.514
LIG_SH2_CRK	1101	1105	PF00017	0.537
LIG_SH2_CRK	1227	1231	PF00017	0.537
LIG_SH2_CRK	1307	1311	PF00017	0.537
LIG_SH2_CRK	337	341	PF00017	0.587
LIG_SH2_CRK	450	454	PF00017	0.546
LIG_SH2_CRK	54	58	PF00017	0.506
LIG_SH2_CRK	702	706	PF00017	0.427
LIG_SH2_GRB2like	1227	1230	PF00017	0.537
LIG_SH2_NCK_1	1101	1105	PF00017	0.537
LIG_SH2_NCK_1	1227	1231	PF00017	0.537
LIG_SH2_NCK_1	54	58	PF00017	0.506
LIG_SH2_SRC	1227	1230	PF00017	0.537
LIG_SH2_SRC	337	340	PF00017	0.590
LIG_SH2_STAP1	124	128	PF00017	0.544
LIG_SH2_STAP1	1307	1311	PF00017	0.537
LIG_SH2_STAP1	609	613	PF00017	0.472
LIG_SH2_STAP1	723	727	PF00017	0.616
LIG_SH2_STAT3	1100	1103	PF00017	0.537
LIG_SH2_STAT3	124	127	PF00017	0.537
LIG_SH2_STAT3	327	330	PF00017	0.774
LIG_SH2_STAT5	1317	1320	PF00017	0.549
LIG_SH2_STAT5	189	192	PF00017	0.579
LIG_SH2_STAT5	311	314	PF00017	0.588
LIG_SH2_STAT5	369	372	PF00017	0.586
LIG_SH2_STAT5	381	384	PF00017	0.478
LIG_SH2_STAT5	416	419	PF00017	0.546
LIG_SH2_STAT5	433	436	PF00017	0.546
LIG_SH2_STAT5	452	455	PF00017	0.546
LIG_SH2_STAT5	605	608	PF00017	0.429
LIG_SH2_STAT5	860	863	PF00017	0.437
LIG_SH2_STAT5	9	12	PF00017	0.563
LIG_SH2_STAT5	904	907	PF00017	0.493
LIG_SH2_STAT5	971	974	PF00017	0.334
LIG_SH3_2	878	883	PF14604	0.586
LIG_SH3_3	1069	1075	PF00018	0.526
LIG_SH3_3	211	217	PF00018	0.707
LIG_SH3_3	29	35	PF00018	0.712
LIG_SH3_3	499	505	PF00018	0.605
LIG_SH3_3	53	59	PF00018	0.644
LIG_SH3_3	658	664	PF00018	0.661
LIG_SH3_3	832	838	PF00018	0.560
LIG_SH3_3	875	881	PF00018	0.573
LIG_SH3_3	929	935	PF00018	0.469
LIG_SUMO_SIM_anti_2	1309	1314	PF11976	0.583
LIG_SUMO_SIM_par_1	1089	1098	PF11976	0.583
LIG_SUMO_SIM_par_1	1308	1314	PF11976	0.537
LIG_SUMO_SIM_par_1	138	145	PF11976	0.646
LIG_SUMO_SIM_par_1	907	912	PF11976	0.527
LIG_TYR_ITIM	448	453	PF00017	0.411
LIG_UBA3_1	180	187	PF00899	0.541
LIG_WRC_WIRS_1	687	692	PF05994	0.414
LIG_WRC_WIRS_1	704	709	PF05994	0.367
LIG_WRC_WIRS_1	903	908	PF05994	0.494
MOD_CDC14_SPxK_1	880	883	PF00782	0.627
MOD_CDK_SPxK_1	266	272	PF00069	0.721
MOD_CDK_SPxK_1	479	485	PF00069	0.667
MOD_CDK_SPxK_1	877	883	PF00069	0.627
MOD_CK1_1	1037	1043	PF00069	0.562
MOD_CK1_1	1049	1055	PF00069	0.488
MOD_CK1_1	1171	1177	PF00069	0.443
MOD_CK1_1	1264	1270	PF00069	0.437
MOD_CK1_1	1274	1280	PF00069	0.224
MOD_CK1_1	145	151	PF00069	0.619
MOD_CK1_1	152	158	PF00069	0.688
MOD_CK1_1	249	255	PF00069	0.765
MOD_CK1_1	266	272	PF00069	0.541
MOD_CK1_1	27	33	PF00069	0.693
MOD_CK1_1	377	383	PF00069	0.590
MOD_CK1_1	414	420	PF00069	0.411
MOD_CK1_1	484	490	PF00069	0.718
MOD_CK1_1	5	11	PF00069	0.489
MOD_CK1_1	504	510	PF00069	0.616
MOD_CK1_1	55	61	PF00069	0.654
MOD_CK1_1	584	590	PF00069	0.522
MOD_CK1_1	629	635	PF00069	0.369
MOD_CK1_1	659	665	PF00069	0.710
MOD_CK1_1	672	678	PF00069	0.585
MOD_CK1_1	735	741	PF00069	0.698
MOD_CK1_1	752	758	PF00069	0.611
MOD_CK1_1	862	868	PF00069	0.526
MOD_CK1_1	874	880	PF00069	0.503
MOD_CK2_1	105	111	PF00069	0.611
MOD_CK2_1	1228	1234	PF00069	0.340
MOD_CK2_1	1274	1280	PF00069	0.402
MOD_CK2_1	158	164	PF00069	0.661
MOD_CK2_1	229	235	PF00069	0.731
MOD_CK2_1	469	475	PF00069	0.561
MOD_CK2_1	57	63	PF00069	0.682
MOD_CK2_1	805	811	PF00069	0.510
MOD_CK2_1	954	960	PF00069	0.423
MOD_GlcNHglycan	1015	1018	PF01048	0.455
MOD_GlcNHglycan	107	110	PF01048	0.697
MOD_GlcNHglycan	1154	1157	PF01048	0.417
MOD_GlcNHglycan	1263	1266	PF01048	0.402
MOD_GlcNHglycan	1327	1330	PF01048	0.463
MOD_GlcNHglycan	1345	1348	PF01048	0.295
MOD_GlcNHglycan	144	147	PF01048	0.626
MOD_GlcNHglycan	160	163	PF01048	0.804
MOD_GlcNHglycan	226	229	PF01048	0.697
MOD_GlcNHglycan	24	27	PF01048	0.693
MOD_GlcNHglycan	399	402	PF01048	0.757
MOD_GlcNHglycan	403	406	PF01048	0.691
MOD_GlcNHglycan	559	562	PF01048	0.495
MOD_GlcNHglycan	631	634	PF01048	0.435
MOD_GlcNHglycan	639	642	PF01048	0.501
MOD_GlcNHglycan	658	661	PF01048	0.389
MOD_GlcNHglycan	746	749	PF01048	0.699
MOD_GlcNHglycan	750	754	PF01048	0.642
MOD_GlcNHglycan	764	767	PF01048	0.397
MOD_GlcNHglycan	956	959	PF01048	0.438
MOD_GlcNHglycan	989	992	PF01048	0.590
MOD_GSK3_1	1028	1035	PF00069	0.594
MOD_GSK3_1	1045	1052	PF00069	0.435
MOD_GSK3_1	1128	1135	PF00069	0.309
MOD_GSK3_1	1169	1176	PF00069	0.449
MOD_GSK3_1	1178	1185	PF00069	0.514
MOD_GSK3_1	1266	1273	PF00069	0.390
MOD_GSK3_1	1285	1292	PF00069	0.423
MOD_GSK3_1	144	151	PF00069	0.685
MOD_GSK3_1	152	159	PF00069	0.657
MOD_GSK3_1	189	196	PF00069	0.676
MOD_GSK3_1	20	27	PF00069	0.703
MOD_GSK3_1	245	252	PF00069	0.755
MOD_GSK3_1	370	377	PF00069	0.573
MOD_GSK3_1	397	404	PF00069	0.729
MOD_GSK3_1	40	47	PF00069	0.431
MOD_GSK3_1	410	417	PF00069	0.336
MOD_GSK3_1	465	472	PF00069	0.564
MOD_GSK3_1	479	486	PF00069	0.614
MOD_GSK3_1	517	524	PF00069	0.443
MOD_GSK3_1	553	560	PF00069	0.598
MOD_GSK3_1	582	589	PF00069	0.432
MOD_GSK3_1	608	615	PF00069	0.507
MOD_GSK3_1	670	677	PF00069	0.630
MOD_GSK3_1	735	742	PF00069	0.718
MOD_GSK3_1	744	751	PF00069	0.546
MOD_GSK3_1	859	866	PF00069	0.444
MOD_GSK3_1	872	879	PF00069	0.593
MOD_GSK3_1	950	957	PF00069	0.554
MOD_LATS_1	581	587	PF00433	0.529
MOD_N-GLC_1	1037	1042	PF02516	0.626
MOD_N-GLC_1	240	245	PF02516	0.722
MOD_N-GLC_1	862	867	PF02516	0.332
MOD_N-GLC_2	1294	1296	PF02516	0.394
MOD_NEK2_1	1020	1025	PF00069	0.503
MOD_NEK2_1	105	110	PF00069	0.556
MOD_NEK2_1	1095	1100	PF00069	0.398
MOD_NEK2_1	1111	1116	PF00069	0.398
MOD_NEK2_1	1258	1263	PF00069	0.416
MOD_NEK2_1	1289	1294	PF00069	0.494
MOD_NEK2_1	149	154	PF00069	0.562
MOD_NEK2_1	2	7	PF00069	0.458
MOD_NEK2_1	205	210	PF00069	0.594
MOD_NEK2_1	318	323	PF00069	0.716
MOD_NEK2_1	557	562	PF00069	0.620
MOD_NEK2_1	601	606	PF00069	0.434
MOD_NEK2_1	708	713	PF00069	0.423
MOD_NEK2_1	740	745	PF00069	0.522
MOD_NEK2_1	859	864	PF00069	0.317
MOD_NEK2_1	926	931	PF00069	0.460
MOD_NEK2_2	521	526	PF00069	0.486
MOD_PIKK_1	1020	1026	PF00454	0.506
MOD_PIKK_1	114	120	PF00454	0.602
MOD_PIKK_1	1182	1188	PF00454	0.442
MOD_PIKK_1	193	199	PF00454	0.589
MOD_PIKK_1	708	714	PF00454	0.423
MOD_PIKK_1	811	817	PF00454	0.635
MOD_PKA_1	1325	1331	PF00069	0.398
MOD_PKA_1	278	284	PF00069	0.721
MOD_PKA_2	1128	1134	PF00069	0.420
MOD_PKA_2	1204	1210	PF00069	0.398
MOD_PKA_2	1258	1264	PF00069	0.416
MOD_PKA_2	1315	1321	PF00069	0.444
MOD_PKA_2	1325	1331	PF00069	0.352
MOD_PKA_2	278	284	PF00069	0.669
MOD_PKA_2	517	523	PF00069	0.555
MOD_PKA_2	582	588	PF00069	0.400
MOD_PKA_2	732	738	PF00069	0.552
MOD_PKA_2	740	746	PF00069	0.526
MOD_PKA_2	762	768	PF00069	0.668
MOD_Plk_1	975	981	PF00069	0.417
MOD_Plk_4	1046	1052	PF00069	0.615
MOD_Plk_4	1062	1068	PF00069	0.350
MOD_Plk_4	1285	1291	PF00069	0.416
MOD_Plk_4	1306	1312	PF00069	0.463
MOD_Plk_4	176	182	PF00069	0.549
MOD_Plk_4	2	8	PF00069	0.418
MOD_Plk_4	27	33	PF00069	0.665
MOD_Plk_4	377	383	PF00069	0.590
MOD_Plk_4	411	417	PF00069	0.411
MOD_Plk_4	507	513	PF00069	0.576
MOD_Plk_4	601	607	PF00069	0.483
MOD_Plk_4	686	692	PF00069	0.487
MOD_Plk_4	703	709	PF00069	0.384
MOD_ProDKin_1	1049	1055	PF00069	0.457
MOD_ProDKin_1	1174	1180	PF00069	0.334
MOD_ProDKin_1	1264	1270	PF00069	0.427
MOD_ProDKin_1	1271	1277	PF00069	0.356
MOD_ProDKin_1	252	258	PF00069	0.777
MOD_ProDKin_1	266	272	PF00069	0.657
MOD_ProDKin_1	479	485	PF00069	0.702
MOD_ProDKin_1	501	507	PF00069	0.649
MOD_ProDKin_1	52	58	PF00069	0.696
MOD_ProDKin_1	659	665	PF00069	0.703
MOD_ProDKin_1	672	678	PF00069	0.538
MOD_ProDKin_1	869	875	PF00069	0.600
MOD_ProDKin_1	877	883	PF00069	0.556
MOD_SUMO_rev_2	1105	1110	PF00179	0.318
MOD_SUMO_rev_2	12	20	PF00179	0.624
TRG_DiLeu_BaEn_1	111	116	PF01217	0.681
TRG_DiLeu_BaEn_2	622	628	PF01217	0.456
TRG_DiLeu_BaLyEn_6	434	439	PF01217	0.507
TRG_DiLeu_BaLyEn_6	609	614	PF01217	0.457
TRG_DiLeu_BaLyEn_6	780	785	PF01217	0.643
TRG_DiLeu_BaLyEn_6	851	856	PF01217	0.424
TRG_DiLeu_BaLyEn_6	929	934	PF01217	0.469
TRG_ENDOCYTIC_2	1085	1088	PF00928	0.398
TRG_ENDOCYTIC_2	1101	1104	PF00928	0.183
TRG_ENDOCYTIC_2	1307	1310	PF00928	0.398
TRG_ENDOCYTIC_2	450	453	PF00928	0.411
TRG_ENDOCYTIC_2	702	705	PF00928	0.426
TRG_ER_diArg_1	1324	1326	PF00400	0.402
TRG_ER_diArg_1	215	218	PF00400	0.594
TRG_ER_diArg_1	277	279	PF00400	0.763
TRG_ER_diArg_1	297	299	PF00400	0.419
TRG_ER_diArg_1	327	329	PF00400	0.727
TRG_ER_diArg_1	420	423	PF00400	0.509
TRG_ER_diArg_1	515	518	PF00400	0.534
TRG_ER_diArg_1	525	528	PF00400	0.647
TRG_ER_diArg_1	599	601	PF00400	0.480
TRG_ER_diArg_1	65	68	PF00400	0.705
TRG_ER_diArg_1	77	79	PF00400	0.545
TRG_ER_diArg_1	780	783	PF00400	0.591
TRG_ER_diArg_1	81	84	PF00400	0.498
TRG_NLS_MonoCore_2	183	188	PF00514	0.547
TRG_NLS_MonoExtN_4	182	188	PF00514	0.544
TRG_Pf-PMV_PEXEL_1	1057	1061	PF00026	0.445
TRG_Pf-PMV_PEXEL_1	349	353	PF00026	0.710
TRG_Pf-PMV_PEXEL_1	422	427	PF00026	0.509
TRG_Pf-PMV_PEXEL_1	599	603	PF00026	0.479
TRG_Pf-PMV_PEXEL_1	68	72	PF00026	0.613
TRG_Pf-PMV_PEXEL_1	842	847	PF00026	0.558
TRG_Pf-PMV_PEXEL_1	90	94	PF00026	0.635

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I170	Leptomonas seymouri	44%	92%
A0A3S7WNM9	Leishmania donovani	90%	100%
A4H3M1	Leishmania braziliensis	69%	100%
E9AG48	Leishmania infantum	90%	100%
E9AJU2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	97%