Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

E9ACG4_LEIMA

TriTrypDb:

LmjF.03.0170 , LMJLV39_030006700 , LMJSD75_030006700

Length:

192

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ACG4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACG4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	114	118	PF00656	0.515
CLV_C14_Caspase3-7	70	74	PF00656	0.818
CLV_C14_Caspase3-7	84	88	PF00656	0.535
DEG_SCF_FBW7_1	58	65	PF00400	0.572
DOC_ANK_TNKS_1	112	119	PF00023	0.545
DOC_CDC14_PxL_1	177	185	PF14671	0.689
DOC_USP7_MATH_1	62	66	PF00917	0.692
DOC_USP7_MATH_1	75	79	PF00917	0.712
DOC_USP7_MATH_1	80	84	PF00917	0.608
DOC_WW_Pin1_4	140	145	PF00397	0.643
DOC_WW_Pin1_4	3	8	PF00397	0.693
DOC_WW_Pin1_4	58	63	PF00397	0.665
DOC_WW_Pin1_4	76	81	PF00397	0.564
LIG_BIR_II_1	1	5	PF00653	0.807
LIG_BIR_III_4	186	190	PF00653	0.567
LIG_CtBP_PxDLS_1	167	171	PF00389	0.778
LIG_FHA_1	47	53	PF00498	0.786
LIG_FHA_1	7	13	PF00498	0.665
LIG_FHA_2	112	118	PF00498	0.499
LIG_LIR_Apic_2	2	8	PF02991	0.736
LIG_LIR_Nem_3	48	53	PF02991	0.787
LIG_PCNA_yPIPBox_3	94	105	PF02747	0.541
LIG_RPA_C_Fungi	108	120	PF08784	0.535
LIG_SH2_CRK	5	9	PF00017	0.699
LIG_SH2_NCK_1	5	9	PF00017	0.575
LIG_SH2_NCK_1	53	57	PF00017	0.575
LIG_SH2_SRC	100	103	PF00017	0.654
LIG_SH2_STAT5	100	103	PF00017	0.654
LIG_SH3_3	1	7	PF00018	0.741
LIG_SH3_3	173	179	PF00018	0.556
LIG_SUMO_SIM_anti_2	172	178	PF11976	0.578
LIG_SUMO_SIM_anti_2	25	30	PF11976	0.610
LIG_SUMO_SIM_par_1	172	178	PF11976	0.546
LIG_TRAF2_1	45	48	PF00917	0.769
MOD_CDK_SPxK_1	140	146	PF00069	0.645
MOD_CK1_1	3	9	PF00069	0.757
MOD_CK1_1	65	71	PF00069	0.708
MOD_CK1_1	83	89	PF00069	0.543
MOD_GlcNHglycan	154	157	PF01048	0.645
MOD_GlcNHglycan	67	70	PF01048	0.779
MOD_GSK3_1	152	159	PF00069	0.660
MOD_GSK3_1	58	65	PF00069	0.799
MOD_GSK3_1	6	13	PF00069	0.657
MOD_GSK3_1	76	83	PF00069	0.494
MOD_N-GLC_1	35	40	PF02516	0.741
MOD_PIKK_1	13	19	PF00454	0.532
MOD_PKA_2	119	125	PF00069	0.725
MOD_PKA_2	75	81	PF00069	0.821
MOD_ProDKin_1	140	146	PF00069	0.645
MOD_ProDKin_1	3	9	PF00069	0.695
MOD_ProDKin_1	58	64	PF00069	0.669
MOD_ProDKin_1	76	82	PF00069	0.563
TRG_ENDOCYTIC_2	53	56	PF00928	0.769
TRG_NES_CRM1_1	25	39	PF08389	0.594

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A451EJM2	Leishmania donovani	84%	100%
A4H3I9	Leishmania braziliensis	65%	100%
A4HRS8	Leishmania infantum	84%	100%
E9AJQ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	99%