Putative ATP-binding cassette protein subfamily F member 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-binding cassette protein subfamily F, member 1, putative

Species:

Leishmania major

UniProt:

E9ACG3_LEIMA

TriTrypDb:

LmjF.03.0160 , LMJLV39_030006600 , LMJSD75_030006600

Length:

724

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2

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Expansion

Sequence features

E9ACG3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACG3

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003824	catalytic activity	1	1
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0016787	hydrolase activity	2	1
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	317	321	PF00656	0.305
CLV_C14_Caspase3-7	500	504	PF00656	0.387
CLV_NRD_NRD_1	155	157	PF00675	0.475
CLV_NRD_NRD_1	159	161	PF00675	0.450
CLV_NRD_NRD_1	176	178	PF00675	0.547
CLV_NRD_NRD_1	30	32	PF00675	0.358
CLV_NRD_NRD_1	715	717	PF00675	0.452
CLV_PCSK_FUR_1	156	160	PF00082	0.464
CLV_PCSK_KEX2_1	123	125	PF00082	0.625
CLV_PCSK_KEX2_1	148	150	PF00082	0.495

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0H2VBH0	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	41%	100%
A0A0H2VFI8	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	30%	100%
A0A0N0P4L2	Leptomonas seymouri	87%	100%
A0A0N1I593	Leptomonas seymouri	36%	100%
A0A0N1PAH6	Leptomonas seymouri	41%	100%
A0A0S4IYK6	Bodo saltans	32%	100%
A0A0S4JRN6	Bodo saltans	37%	100%
A0A1X0P0L3	Trypanosomatidae	37%	100%
A0A1X0P688	Trypanosomatidae	43%	100%
A0A1X0P8V9	Trypanosomatidae	72%	100%

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