LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
E9ACG1_LEIMA
TriTrypDb:
LmjF.03.0140 , LMJLV39_030006400 , LMJSD75_030006400
Length:
139

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ACG1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACG1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 110 112 PF00675 0.629
CLV_NRD_NRD_1 121 123 PF00675 0.417
CLV_NRD_NRD_1 32 34 PF00675 0.525
CLV_PCSK_FUR_1 108 112 PF00082 0.627
CLV_PCSK_KEX2_1 110 112 PF00082 0.606
CLV_PCSK_KEX2_1 31 33 PF00082 0.524
CLV_PCSK_PC1ET2_1 31 33 PF00082 0.554
CLV_PCSK_SKI1_1 111 115 PF00082 0.538
DEG_APCC_DBOX_1 110 118 PF00400 0.611
DOC_MAPK_gen_1 120 129 PF00069 0.535
DOC_MAPK_MEF2A_6 62 69 PF00069 0.574
DOC_MAPK_NFAT4_5 62 70 PF00069 0.652
DOC_USP7_MATH_1 86 90 PF00917 0.691
DOC_USP7_MATH_1 92 96 PF00917 0.676
LIG_LIR_Gen_1 38 48 PF02991 0.528
LIG_LIR_Nem_3 38 44 PF02991 0.492
LIG_Rb_LxCxE_1 51 68 PF01857 0.442
LIG_SH2_CRK 23 27 PF00017 0.621
LIG_SH2_STAT5 13 16 PF00017 0.582
LIG_SH2_STAT5 43 46 PF00017 0.561
LIG_TRAF2_1 113 116 PF00917 0.612
MOD_CK1_1 12 18 PF00069 0.556
MOD_CK1_1 80 86 PF00069 0.718
MOD_CK2_1 96 102 PF00069 0.540
MOD_GlcNHglycan 5 8 PF01048 0.595
MOD_GlcNHglycan 79 82 PF01048 0.661
MOD_GlcNHglycan 88 91 PF01048 0.656
MOD_GSK3_1 92 99 PF00069 0.668
MOD_PIKK_1 96 102 PF00454 0.631
MOD_PKA_2 77 83 PF00069 0.745
MOD_PKA_2 9 15 PF00069 0.577
MOD_Plk_1 92 98 PF00069 0.560
MOD_Plk_4 9 15 PF00069 0.614
TRG_ENDOCYTIC_2 23 26 PF00928 0.653
TRG_ER_diArg_1 62 65 PF00400 0.548

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IJS5 Leptomonas seymouri 60% 97%
A0A0S4JDM7 Bodo saltans 43% 100%
A0A1X0P8N0 Trypanosomatidae 45% 100%
A0A422N7L0 Trypanosoma rangeli 46% 100%
A0A451EJL9 Leishmania donovani 96% 100%
A4H3I6 Leishmania braziliensis 80% 100%
D0A221 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
E9AG33 Leishmania infantum 96% 100%
E9AJP9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS