Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9ACC5_LEIMA

TriTrypDb:

LmjF.02.0510 , LMJLV39_020010200 , LMJSD75_020010300

Length:

170

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ACC5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ACC5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	52	54	PF00675	0.648
CLV_NRD_NRD_1	58	60	PF00675	0.629
CLV_PCSK_KEX2_1	52	54	PF00082	0.648
CLV_PCSK_KEX2_1	58	60	PF00082	0.629
CLV_PCSK_SKI1_1	109	113	PF00082	0.577
DEG_COP1_1	117	126	PF00400	0.459
DEG_Nend_Nbox_1	1	3	PF02207	0.650
DOC_CYCLIN_yCln2_LP_2	112	118	PF00134	0.602
DOC_USP7_MATH_1	85	89	PF00917	0.607
DOC_WW_Pin1_4	27	32	PF00397	0.679
DOC_WW_Pin1_4	69	74	PF00397	0.656
LIG_14-3-3_CanoR_1	11	17	PF00244	0.618
LIG_14-3-3_CanoR_1	67	73	PF00244	0.627
LIG_Actin_WH2_2	44	60	PF00022	0.668
LIG_BIR_III_4	117	121	PF00653	0.614
LIG_deltaCOP1_diTrp_1	107	111	PF00928	0.564
LIG_FHA_1	76	82	PF00498	0.558
LIG_FHA_2	143	149	PF00498	0.581
LIG_FHA_2	161	167	PF00498	0.614
LIG_FHA_2	91	97	PF00498	0.624
LIG_LIR_Gen_1	29	40	PF02991	0.599
LIG_LIR_Nem_3	107	111	PF02991	0.678
LIG_LIR_Nem_3	29	35	PF02991	0.643
LIG_SH2_SRC	89	92	PF00017	0.502
LIG_SH2_STAT3	161	164	PF00017	0.592
LIG_TRAF2_1	93	96	PF00917	0.624
LIG_TRAF2_1	99	102	PF00917	0.550
MOD_CK1_1	33	39	PF00069	0.546
MOD_CK1_1	69	75	PF00069	0.630
MOD_CK2_1	142	148	PF00069	0.640
MOD_CK2_1	23	29	PF00069	0.641
MOD_CK2_1	90	96	PF00069	0.631
MOD_GlcNHglycan	124	127	PF01048	0.605
MOD_GlcNHglycan	36	39	PF01048	0.591
MOD_GlcNHglycan	68	71	PF01048	0.637
MOD_GSK3_1	12	19	PF00069	0.496
MOD_GSK3_1	2	9	PF00069	0.622
MOD_GSK3_1	23	30	PF00069	0.623
MOD_GSK3_1	43	50	PF00069	0.618
MOD_GSK3_1	59	66	PF00069	0.522
MOD_GSK3_1	69	76	PF00069	0.563
MOD_NEK2_1	16	21	PF00069	0.454
MOD_NEK2_1	47	52	PF00069	0.645
MOD_NEK2_1	6	11	PF00069	0.589
MOD_PIKK_1	160	166	PF00454	0.614
MOD_PIKK_1	9	15	PF00454	0.510
MOD_PKA_2	2	8	PF00069	0.607
MOD_PKA_2	66	72	PF00069	0.613
MOD_ProDKin_1	27	33	PF00069	0.682
MOD_ProDKin_1	69	75	PF00069	0.654
TRG_DiLeu_BaEn_2	106	112	PF01217	0.571
TRG_ER_diArg_1	51	53	PF00400	0.651
TRG_ER_diArg_1	57	59	PF00400	0.632
TRG_Pf-PMV_PEXEL_1	137	141	PF00026	0.600
TRG_Pf-PMV_PEXEL_1	151	155	PF00026	0.424
TRG_Pf-PMV_PEXEL_1	45	49	PF00026	0.668

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A451EJI7	Leishmania donovani	91%	100%
A4H3E2	Leishmania braziliensis	69%	100%
A4HRP6	Leishmania infantum	91%	100%
E9AJL3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%