LeishMANIAdb
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Glycosyltransferase_(GlcNAc)_-_putative

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Glycosyltransferase_(GlcNAc)_-_putative
Gene product:
glycosyltransferase (GlcNAc), putative
Species:
Leishmania major
UniProt:
E9AC99_LEIMA
TriTrypDb:
LmjF.02.0240 * , LMJLV39_020007300 * , LMJSD75_020007300 *
Length:
904

Annotations

LeishMANIAdb annotations

A conserved glycosyltransferase enzyme. Only expanded in T cruzi lineage.. Localization: Golgi (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 10
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Cellular components
Term Name Level Count
GO:0016020 membrane 2 7
GO:0110165 cellular anatomical entity 1 7

Expansion

Sequence features

E9AC99
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AC99

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 1
GO:0016740 transferase activity 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 106 110 PF00656 0.549
CLV_C14_Caspase3-7 248 252 PF00656 0.487
CLV_C14_Caspase3-7 261 265 PF00656 0.401
CLV_MEL_PAP_1 430 436 PF00089 0.396
CLV_NRD_NRD_1 107 109 PF00675 0.718
CLV_NRD_NRD_1 129 131 PF00675 0.696
CLV_NRD_NRD_1 133 135 PF00675 0.689
CLV_NRD_NRD_1 156 158 PF00675 0.658
CLV_NRD_NRD_1 168 170 PF00675 0.700
CLV_NRD_NRD_1 233 235 PF00675 0.751
CLV_NRD_NRD_1 335 337 PF00675 0.774
CLV_NRD_NRD_1 403 405 PF00675 0.687
CLV_NRD_NRD_1 667 669 PF00675 0.320
CLV_PCSK_FUR_1 333 337 PF00082 0.744
CLV_PCSK_KEX2_1 107 109 PF00082 0.736
CLV_PCSK_KEX2_1 133 135 PF00082 0.692
CLV_PCSK_KEX2_1 155 157 PF00082 0.672
CLV_PCSK_KEX2_1 26 28 PF00082 0.508
CLV_PCSK_KEX2_1 335 337 PF00082 0.774
CLV_PCSK_KEX2_1 403 405 PF00082 0.687
CLV_PCSK_KEX2_1 667 669 PF00082 0.342
CLV_PCSK_PC1ET2_1 26 28 PF00082 0.503
CLV_PCSK_PC7_1 331 337 PF00082 0.765
CLV_PCSK_SKI1_1 133 137 PF00082 0.752
CLV_PCSK_SKI1_1 156 160 PF00082 0.643
CLV_PCSK_SKI1_1 23 27 PF00082 0.556
CLV_PCSK_SKI1_1 235 239 PF00082 0.759
CLV_PCSK_SKI1_1 673 677 PF00082 0.299
DEG_APCC_DBOX_1 18 26 PF00400 0.704
DEG_APCC_DBOX_1 466 474 PF00400 0.591
DEG_COP1_1 544 552 PF00400 0.538
DEG_SCF_SKP2-CKS1_1 46 53 PF00560 0.590
DOC_CDC14_PxL_1 513 521 PF14671 0.520
DOC_CKS1_1 552 557 PF01111 0.556
DOC_CKS1_1 799 804 PF01111 0.249
DOC_CYCLIN_RxL_1 130 139 PF00134 0.447
DOC_CYCLIN_RxL_1 21 33 PF00134 0.674
DOC_CYCLIN_RxL_1 34 48 PF00134 0.596
DOC_CYCLIN_RxL_1 801 812 PF00134 0.302
DOC_CYCLIN_yCln2_LP_2 751 757 PF00134 0.499
DOC_MAPK_gen_1 524 534 PF00069 0.534
DOC_MAPK_gen_1 832 839 PF00069 0.334
DOC_MAPK_MEF2A_6 527 536 PF00069 0.550
DOC_MAPK_MEF2A_6 640 648 PF00069 0.556
DOC_PP1_RVXF_1 38 45 PF00149 0.673
DOC_PP1_RVXF_1 802 809 PF00149 0.356
DOC_PP1_RVXF_1 834 840 PF00149 0.341
DOC_PP2B_LxvP_1 463 466 PF13499 0.679
DOC_PP4_FxxP_1 434 437 PF00568 0.417
DOC_SPAK_OSR1_1 433 437 PF12202 0.417
DOC_USP7_MATH_1 2 6 PF00917 0.708
DOC_USP7_MATH_1 203 207 PF00917 0.563
DOC_USP7_MATH_1 278 282 PF00917 0.524
DOC_USP7_MATH_1 437 441 PF00917 0.317
DOC_USP7_MATH_1 491 495 PF00917 0.592
DOC_USP7_MATH_1 52 56 PF00917 0.687
DOC_WW_Pin1_4 356 361 PF00397 0.534
DOC_WW_Pin1_4 455 460 PF00397 0.678
DOC_WW_Pin1_4 47 52 PF00397 0.627
DOC_WW_Pin1_4 542 547 PF00397 0.556
DOC_WW_Pin1_4 551 556 PF00397 0.488
DOC_WW_Pin1_4 798 803 PF00397 0.299
DOC_WW_Pin1_4 820 825 PF00397 0.267
LIG_14-3-3_CanoR_1 124 132 PF00244 0.517
LIG_14-3-3_CanoR_1 134 144 PF00244 0.385
LIG_14-3-3_CanoR_1 160 165 PF00244 0.436
LIG_14-3-3_CanoR_1 303 309 PF00244 0.596
LIG_14-3-3_CanoR_1 34 40 PF00244 0.744
LIG_14-3-3_CanoR_1 403 411 PF00244 0.487
LIG_14-3-3_CanoR_1 581 586 PF00244 0.551
LIG_14-3-3_CanoR_1 694 700 PF00244 0.499
LIG_14-3-3_CanoR_1 737 745 PF00244 0.567
LIG_14-3-3_CanoR_1 791 800 PF00244 0.299
LIG_14-3-3_CanoR_1 813 817 PF00244 0.320
LIG_14-3-3_CanoR_1 91 101 PF00244 0.523
LIG_Actin_WH2_2 604 620 PF00022 0.520
LIG_APCC_ABBAyCdc20_2 727 733 PF00400 0.538
LIG_BIR_III_2 251 255 PF00653 0.442
LIG_FHA_1 299 305 PF00498 0.571
LIG_FHA_1 498 504 PF00498 0.569
LIG_FHA_1 543 549 PF00498 0.524
LIG_FHA_1 552 558 PF00498 0.588
LIG_FHA_1 643 649 PF00498 0.548
LIG_FHA_1 695 701 PF00498 0.502
LIG_FHA_1 841 847 PF00498 0.249
LIG_FHA_2 104 110 PF00498 0.567
LIG_FHA_2 189 195 PF00498 0.502
LIG_FHA_2 259 265 PF00498 0.512
LIG_FHA_2 479 485 PF00498 0.720
LIG_FHA_2 592 598 PF00498 0.494
LIG_IBAR_NPY_1 859 861 PF08397 0.302
LIG_IRF3_LxIS_1 68 75 PF10401 0.292
LIG_LIR_Apic_2 432 437 PF02991 0.417
LIG_LIR_Apic_2 554 559 PF02991 0.556
LIG_LIR_Gen_1 194 205 PF02991 0.489
LIG_LIR_Gen_1 306 317 PF02991 0.514
LIG_LIR_Gen_1 392 402 PF02991 0.489
LIG_LIR_Gen_1 420 430 PF02991 0.357
LIG_LIR_Gen_1 502 510 PF02991 0.499
LIG_LIR_Gen_1 733 743 PF02991 0.534
LIG_LIR_Gen_1 75 84 PF02991 0.449
LIG_LIR_Gen_1 763 772 PF02991 0.267
LIG_LIR_Gen_1 858 869 PF02991 0.334
LIG_LIR_Nem_3 194 200 PF02991 0.492
LIG_LIR_Nem_3 306 312 PF02991 0.518
LIG_LIR_Nem_3 392 397 PF02991 0.494
LIG_LIR_Nem_3 420 426 PF02991 0.463
LIG_LIR_Nem_3 502 507 PF02991 0.499
LIG_LIR_Nem_3 551 556 PF02991 0.524
LIG_LIR_Nem_3 629 633 PF02991 0.475
LIG_LIR_Nem_3 687 693 PF02991 0.548
LIG_LIR_Nem_3 733 738 PF02991 0.534
LIG_LIR_Nem_3 75 79 PF02991 0.449
LIG_LIR_Nem_3 763 767 PF02991 0.434
LIG_LIR_Nem_3 794 800 PF02991 0.318
LIG_LIR_Nem_3 858 864 PF02991 0.314
LIG_LIR_Nem_3 882 886 PF02991 0.339
LIG_LIR_Nem_3 894 900 PF02991 0.433
LIG_MYND_1 546 550 PF01753 0.514
LIG_MYND_1 555 559 PF01753 0.480
LIG_MYND_3 192 196 PF01753 0.487
LIG_NRBOX 197 203 PF00104 0.483
LIG_NRBOX 67 73 PF00104 0.439
LIG_PCNA_yPIPBox_3 868 881 PF02747 0.341
LIG_Pex14_1 793 797 PF04695 0.299
LIG_Pex14_2 654 658 PF04695 0.499
LIG_Pex14_2 705 709 PF04695 0.541
LIG_Pex14_2 760 764 PF04695 0.392
LIG_PTB_Apo_2 729 736 PF02174 0.538
LIG_PTB_Phospho_1 729 735 PF10480 0.538
LIG_REV1ctd_RIR_1 142 150 PF16727 0.376
LIG_SH2_CRK 405 409 PF00017 0.478
LIG_SH2_CRK 423 427 PF00017 0.252
LIG_SH2_NCK_1 388 392 PF00017 0.484
LIG_SH2_NCK_1 423 427 PF00017 0.356
LIG_SH2_NCK_1 731 735 PF00017 0.525
LIG_SH2_PTP2 533 536 PF00017 0.491
LIG_SH2_PTP2 735 738 PF00017 0.556
LIG_SH2_PTP2 861 864 PF00017 0.314
LIG_SH2_SRC 861 864 PF00017 0.302
LIG_SH2_SRC 881 884 PF00017 0.279
LIG_SH2_STAP1 37 41 PF00017 0.576
LIG_SH2_STAP1 423 427 PF00017 0.325
LIG_SH2_STAP1 788 792 PF00017 0.299
LIG_SH2_STAT3 827 830 PF00017 0.328
LIG_SH2_STAT5 197 200 PF00017 0.492
LIG_SH2_STAT5 37 40 PF00017 0.571
LIG_SH2_STAT5 480 483 PF00017 0.639
LIG_SH2_STAT5 533 536 PF00017 0.491
LIG_SH2_STAT5 553 556 PF00017 0.422
LIG_SH2_STAT5 603 606 PF00017 0.502
LIG_SH2_STAT5 699 702 PF00017 0.499
LIG_SH2_STAT5 711 714 PF00017 0.499
LIG_SH2_STAT5 735 738 PF00017 0.556
LIG_SH2_STAT5 779 782 PF00017 0.341
LIG_SH2_STAT5 800 803 PF00017 0.349
LIG_SH2_STAT5 811 814 PF00017 0.310
LIG_SH2_STAT5 827 830 PF00017 0.290
LIG_SH2_STAT5 861 864 PF00017 0.314
LIG_SH3_1 769 775 PF00018 0.336
LIG_SH3_3 368 374 PF00018 0.544
LIG_SH3_3 769 775 PF00018 0.336
LIG_SH3_3 82 88 PF00018 0.358
LIG_SH3_3 848 854 PF00018 0.341
LIG_SH3_3 897 903 PF00018 0.402
LIG_SUMO_SIM_anti_2 310 316 PF11976 0.519
LIG_SUMO_SIM_anti_2 457 464 PF11976 0.699
LIG_SUMO_SIM_par_1 220 226 PF11976 0.456
LIG_SUMO_SIM_par_1 642 650 PF11976 0.514
LIG_SUMO_SIM_par_1 69 75 PF11976 0.314
LIG_SUMO_SIM_par_1 83 89 PF11976 0.305
LIG_TRAF2_1 211 214 PF00917 0.509
LIG_TRAF2_1 341 344 PF00917 0.505
LIG_TYR_ITIM 397 402 PF00017 0.485
LIG_UBA3_1 164 170 PF00899 0.481
LIG_UBA3_1 665 673 PF00899 0.556
LIG_WRC_WIRS_1 197 202 PF05994 0.427
LIG_WRC_WIRS_1 296 301 PF05994 0.499
LIG_WRC_WIRS_1 73 78 PF05994 0.339
LIG_WRC_WIRS_1 761 766 PF05994 0.341
MOD_CDK_SPxK_1 47 53 PF00069 0.590
MOD_CDK_SPxK_1 798 804 PF00069 0.341
MOD_CDK_SPxxK_3 356 363 PF00069 0.537
MOD_CK1_1 123 129 PF00069 0.526
MOD_CK1_1 298 304 PF00069 0.587
MOD_CK1_1 458 464 PF00069 0.673
MOD_CK1_1 496 502 PF00069 0.661
MOD_CK1_1 5 11 PF00069 0.745
MOD_CK1_1 506 512 PF00069 0.504
MOD_CK1_1 763 769 PF00069 0.367
MOD_CK2_1 188 194 PF00069 0.489
MOD_CK2_1 294 300 PF00069 0.507
MOD_CK2_1 591 597 PF00069 0.504
MOD_CK2_1 718 724 PF00069 0.525
MOD_Cter_Amidation 232 235 PF01082 0.715
MOD_GlcNHglycan 125 128 PF01048 0.715
MOD_GlcNHglycan 205 208 PF01048 0.664
MOD_GlcNHglycan 367 371 PF01048 0.742
MOD_GlcNHglycan 4 7 PF01048 0.562
MOD_GlcNHglycan 405 408 PF01048 0.769
MOD_GlcNHglycan 423 426 PF01048 0.675
MOD_GlcNHglycan 495 498 PF01048 0.384
MOD_GlcNHglycan 720 723 PF01048 0.260
MOD_GlcNHglycan 739 742 PF01048 0.266
MOD_GlcNHglycan 8 11 PF01048 0.536
MOD_GlcNHglycan 814 817 PF01048 0.566
MOD_GSK3_1 184 191 PF00069 0.503
MOD_GSK3_1 2 9 PF00069 0.701
MOD_GSK3_1 294 301 PF00069 0.493
MOD_GSK3_1 412 419 PF00069 0.495
MOD_GSK3_1 43 50 PF00069 0.591
MOD_GSK3_1 493 500 PF00069 0.653
MOD_N-GLC_1 160 165 PF02516 0.700
MOD_N-GLC_1 229 234 PF02516 0.593
MOD_N-GLC_1 855 860 PF02516 0.499
MOD_NEK2_1 101 106 PF00069 0.522
MOD_NEK2_1 188 193 PF00069 0.570
MOD_NEK2_1 229 234 PF00069 0.393
MOD_NEK2_1 273 278 PF00069 0.512
MOD_NEK2_1 522 527 PF00069 0.514
MOD_NEK2_1 54 59 PF00069 0.631
MOD_NEK2_1 661 666 PF00069 0.555
MOD_NEK2_1 72 77 PF00069 0.303
MOD_NEK2_1 760 765 PF00069 0.415
MOD_NEK2_1 840 845 PF00069 0.394
MOD_NEK2_1 94 99 PF00069 0.508
MOD_NEK2_2 35 40 PF00069 0.569
MOD_PIKK_1 52 58 PF00454 0.709
MOD_PIKK_1 620 626 PF00454 0.502
MOD_PIKK_1 826 832 PF00454 0.289
MOD_PIKK_1 92 98 PF00454 0.485
MOD_PKA_1 403 409 PF00069 0.467
MOD_PKA_2 123 129 PF00069 0.441
MOD_PKA_2 302 308 PF00069 0.538
MOD_PKA_2 403 409 PF00069 0.467
MOD_PKA_2 693 699 PF00069 0.499
MOD_PKA_2 812 818 PF00069 0.320
MOD_PKB_1 579 587 PF00069 0.520
MOD_Plk_1 160 166 PF00069 0.481
MOD_Plk_1 642 648 PF00069 0.502
MOD_Plk_1 864 870 PF00069 0.341
MOD_Plk_4 160 166 PF00069 0.481
MOD_Plk_4 196 202 PF00069 0.483
MOD_Plk_4 389 395 PF00069 0.449
MOD_Plk_4 458 464 PF00069 0.695
MOD_Plk_4 499 505 PF00069 0.487
MOD_Plk_4 515 521 PF00069 0.565
MOD_Plk_4 642 648 PF00069 0.554
MOD_Plk_4 661 667 PF00069 0.541
MOD_Plk_4 763 769 PF00069 0.336
MOD_ProDKin_1 356 362 PF00069 0.535
MOD_ProDKin_1 455 461 PF00069 0.676
MOD_ProDKin_1 47 53 PF00069 0.626
MOD_ProDKin_1 542 548 PF00069 0.556
MOD_ProDKin_1 551 557 PF00069 0.488
MOD_ProDKin_1 798 804 PF00069 0.299
MOD_ProDKin_1 820 826 PF00069 0.267
MOD_SUMO_for_1 322 325 PF00179 0.428
MOD_SUMO_rev_2 123 132 PF00179 0.456
MOD_SUMO_rev_2 670 675 PF00179 0.556
TRG_DiLeu_BaEn_1 483 488 PF01217 0.686
TRG_DiLeu_BaEn_1 642 647 PF01217 0.541
TRG_DiLeu_BaEn_2 195 201 PF01217 0.480
TRG_DiLeu_BaEn_2 222 228 PF01217 0.485
TRG_DiLeu_BaLyEn_6 131 136 PF01217 0.481
TRG_DiLeu_BaLyEn_6 24 29 PF01217 0.705
TRG_DiLeu_BaLyEn_6 449 454 PF01217 0.716
TRG_DiLeu_BaLyEn_6 97 102 PF01217 0.511
TRG_ENDOCYTIC_2 197 200 PF00928 0.431
TRG_ENDOCYTIC_2 399 402 PF00928 0.434
TRG_ENDOCYTIC_2 405 408 PF00928 0.447
TRG_ENDOCYTIC_2 423 426 PF00928 0.462
TRG_ENDOCYTIC_2 510 513 PF00928 0.520
TRG_ENDOCYTIC_2 533 536 PF00928 0.520
TRG_ENDOCYTIC_2 633 636 PF00928 0.506
TRG_ENDOCYTIC_2 711 714 PF00928 0.502
TRG_ENDOCYTIC_2 735 738 PF00928 0.538
TRG_ENDOCYTIC_2 861 864 PF00928 0.317
TRG_ENDOCYTIC_2 883 886 PF00928 0.424
TRG_ER_diArg_1 132 134 PF00400 0.487
TRG_ER_diArg_1 154 157 PF00400 0.469
TRG_ER_diArg_1 330 333 PF00400 0.550
TRG_ER_diArg_1 334 336 PF00400 0.545
TRG_ER_diArg_1 402 404 PF00400 0.477
TRG_ER_diArg_1 578 581 PF00400 0.535
TRG_ER_diArg_1 615 618 PF00400 0.512
TRG_ER_diArg_1 666 668 PF00400 0.520
TRG_ER_diArg_1 833 836 PF00400 0.307
TRG_Pf-PMV_PEXEL_1 134 139 PF00026 0.661
TRG_Pf-PMV_PEXEL_1 244 248 PF00026 0.625
TRG_Pf-PMV_PEXEL_1 667 671 PF00026 0.404
TRG_Pf-PMV_PEXEL_1 844 849 PF00026 0.449

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P2W0 Leptomonas seymouri 52% 95%
A0A3S5H4Z0 Leishmania donovani 92% 100%
A4H3C0 Leishmania braziliensis 75% 100%
A4HRS4 Leishmania infantum 92% 100%
C9ZJ13 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%
E9AJI7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS