LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
E9AC83_LEIMA
TriTrypDb:
LmjF.02.0085 *
Length:
314

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AC83
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AC83

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 145 147 PF00675 0.543
CLV_NRD_NRD_1 240 242 PF00675 0.627
CLV_NRD_NRD_1 3 5 PF00675 0.539
CLV_NRD_NRD_1 31 33 PF00675 0.741
CLV_NRD_NRD_1 312 314 PF00675 0.606
CLV_NRD_NRD_1 42 44 PF00675 0.696
CLV_PCSK_KEX2_1 145 147 PF00082 0.543
CLV_PCSK_KEX2_1 242 244 PF00082 0.656
CLV_PCSK_KEX2_1 3 5 PF00082 0.539
CLV_PCSK_KEX2_1 31 33 PF00082 0.742
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3R7LQ19 Trypanosoma rangeli 33% 100%
A0A3S5H4Y0 Leishmania donovani 88% 100%
A4H3B3 Leishmania braziliensis 64% 100%
A4HRL1 Leishmania infantum 88% 100%
C9ZIZ9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
E9AJH5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 95%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS