LeishMANIAdb
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HSP70-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
HSP70-like protein
Gene product:
HSP70-like protein
Species:
Leishmania major
UniProt:
E9AC55_LEIMA
TriTrypDb:
LmjF.01.0640 , LMJLV39_010011700 * , LMJSD75_010011700 *
Length:
1112

Annotations

LeishMANIAdb annotations

Appears to be a secreted chaperone, related to mammalian HYOU1 proteins. Probably ER-localized as in other eukaryotes

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 2, no: 6
NetGPI no yes: 0, no: 8
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 2
GO:0005737 cytoplasm 2 2
GO:0005788 endoplasmic reticulum lumen 5 2
GO:0016020 membrane 2 3
GO:0031974 membrane-enclosed lumen 2 2
GO:0032991 protein-containing complex 1 2
GO:0034663 endoplasmic reticulum chaperone complex 3 2
GO:0043226 organelle 2 9
GO:0043227 membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043231 intracellular membrane-bounded organelle 4 2
GO:0043233 organelle lumen 3 2
GO:0070013 intracellular organelle lumen 4 2
GO:0110165 cellular anatomical entity 1 9
GO:0140534 endoplasmic reticulum protein-containing complex 2 2

Expansion

Sequence features

E9AC55
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AC55

Function

Biological processes
Term Name Level Count
GO:0006457 protein folding 2 2
GO:0006458 'de novo' protein folding 3 2
GO:0006508 proteolysis 4 2
GO:0006511 ubiquitin-dependent protein catabolic process 7 2
GO:0006807 nitrogen compound metabolic process 2 2
GO:0006950 response to stress 2 2
GO:0006986 response to unfolded protein 4 2
GO:0007165 signal transduction 2 2
GO:0008152 metabolic process 1 2
GO:0009056 catabolic process 2 2
GO:0009057 macromolecule catabolic process 4 2
GO:0009987 cellular process 1 2
GO:0010033 response to organic substance 3 2
GO:0010243 response to organonitrogen compound 4 2
GO:0010498 proteasomal protein catabolic process 5 2
GO:0019538 protein metabolic process 3 2
GO:0019941 modification-dependent protein catabolic process 6 2
GO:0030163 protein catabolic process 4 2
GO:0030433 ubiquitin-dependent ERAD pathway 6 2
GO:0030968 endoplasmic reticulum unfolded protein response 3 2
GO:0033554 cellular response to stress 3 2
GO:0034620 cellular response to unfolded protein 5 2
GO:0034976 response to endoplasmic reticulum stress 4 2
GO:0035966 response to topologically incorrect protein 3 2
GO:0035967 cellular response to topologically incorrect protein 4 2
GO:0036503 ERAD pathway 5 2
GO:0042026 protein refolding 3 2
GO:0042221 response to chemical 2 2
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 6 2
GO:0043170 macromolecule metabolic process 3 2
GO:0043632 modification-dependent macromolecule catabolic process 5 2
GO:0044237 cellular metabolic process 2 2
GO:0044238 primary metabolic process 2 2
GO:0044248 cellular catabolic process 3 2
GO:0044260 obsolete cellular macromolecule metabolic process 3 2
GO:0044265 obsolete cellular macromolecule catabolic process 4 2
GO:0050789 regulation of biological process 2 2
GO:0050794 regulation of cellular process 3 2
GO:0050896 response to stimulus 1 2
GO:0051084 'de novo' post-translational protein folding 4 2
GO:0051085 chaperone cofactor-dependent protein refolding 4 2
GO:0051603 proteolysis involved in protein catabolic process 5 2
GO:0051716 cellular response to stimulus 2 2
GO:0061077 chaperone-mediated protein folding 3 2
GO:0065007 biological regulation 1 2
GO:0070887 cellular response to chemical stimulus 3 2
GO:0071310 cellular response to organic substance 4 2
GO:0071704 organic substance metabolic process 2 2
GO:1901564 organonitrogen compound metabolic process 3 2
GO:1901565 organonitrogen compound catabolic process 4 2
GO:1901575 organic substance catabolic process 3 2
GO:1901698 response to nitrogen compound 3 2
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 9
GO:0003824 catalytic activity 1 2
GO:0005488 binding 1 9
GO:0005515 protein binding 2 2
GO:0005524 ATP binding 5 9
GO:0016462 pyrophosphatase activity 5 2
GO:0016787 hydrolase activity 2 2
GO:0016817 hydrolase activity, acting on acid anhydrides 3 2
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 2
GO:0016887 ATP hydrolysis activity 7 2
GO:0017076 purine nucleotide binding 4 9
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 2
GO:0030554 adenyl nucleotide binding 5 9
GO:0031072 heat shock protein binding 3 2
GO:0032553 ribonucleotide binding 3 9
GO:0032555 purine ribonucleotide binding 4 9
GO:0032559 adenyl ribonucleotide binding 5 9
GO:0035639 purine ribonucleoside triphosphate binding 4 9
GO:0036094 small molecule binding 2 9
GO:0043167 ion binding 2 9
GO:0043168 anion binding 3 9
GO:0044183 protein folding chaperone 1 9
GO:0051082 unfolded protein binding 3 2
GO:0051787 misfolded protein binding 3 2
GO:0097159 organic cyclic compound binding 2 9
GO:0097367 carbohydrate derivative binding 2 9
GO:0140657 ATP-dependent activity 1 9
GO:0140662 ATP-dependent protein folding chaperone 2 9
GO:1901265 nucleoside phosphate binding 3 9
GO:1901363 heterocyclic compound binding 2 9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 126 130 PF00656 0.616
CLV_C14_Caspase3-7 356 360 PF00656 0.565
CLV_C14_Caspase3-7 789 793 PF00656 0.462
CLV_MEL_PAP_1 984 990 PF00089 0.512
CLV_NRD_NRD_1 1016 1018 PF00675 0.460
CLV_NRD_NRD_1 1030 1032 PF00675 0.450
CLV_NRD_NRD_1 148 150 PF00675 0.545
CLV_NRD_NRD_1 28 30 PF00675 0.611
CLV_NRD_NRD_1 287 289 PF00675 0.628
CLV_NRD_NRD_1 352 354 PF00675 0.549
CLV_NRD_NRD_1 376 378 PF00675 0.565
CLV_NRD_NRD_1 381 383 PF00675 0.530
CLV_NRD_NRD_1 522 524 PF00675 0.490
CLV_NRD_NRD_1 539 541 PF00675 0.323
CLV_NRD_NRD_1 608 610 PF00675 0.302
CLV_NRD_NRD_1 65 67 PF00675 0.528
CLV_NRD_NRD_1 745 747 PF00675 0.549
CLV_NRD_NRD_1 825 827 PF00675 0.558
CLV_NRD_NRD_1 849 851 PF00675 0.679
CLV_PCSK_FUR_1 1028 1032 PF00082 0.463
CLV_PCSK_FUR_1 847 851 PF00082 0.692
CLV_PCSK_KEX2_1 1016 1018 PF00082 0.467
CLV_PCSK_KEX2_1 1030 1032 PF00082 0.457
CLV_PCSK_KEX2_1 28 30 PF00082 0.613
CLV_PCSK_KEX2_1 287 289 PF00082 0.628
CLV_PCSK_KEX2_1 352 354 PF00082 0.493
CLV_PCSK_KEX2_1 381 383 PF00082 0.511
CLV_PCSK_KEX2_1 522 524 PF00082 0.490
CLV_PCSK_KEX2_1 539 541 PF00082 0.331
CLV_PCSK_KEX2_1 608 610 PF00082 0.282
CLV_PCSK_KEX2_1 65 67 PF00082 0.531
CLV_PCSK_KEX2_1 849 851 PF00082 0.733
CLV_PCSK_PC7_1 377 383 PF00082 0.453
CLV_PCSK_PC7_1 518 524 PF00082 0.348
CLV_PCSK_PC7_1 535 541 PF00082 0.282
CLV_PCSK_SKI1_1 1105 1109 PF00082 0.418
CLV_PCSK_SKI1_1 294 298 PF00082 0.624
CLV_PCSK_SKI1_1 412 416 PF00082 0.402
CLV_PCSK_SKI1_1 557 561 PF00082 0.377
CLV_PCSK_SKI1_1 616 620 PF00082 0.348
DEG_APCC_DBOX_1 756 764 PF00400 0.463
DEG_SCF_FBW7_1 956 961 PF00400 0.544
DEG_SPOP_SBC_1 14 18 PF00917 0.519
DEG_SPOP_SBC_1 273 277 PF00917 0.539
DEG_SPOP_SBC_1 430 434 PF00917 0.339
DOC_ANK_TNKS_1 644 651 PF00023 0.283
DOC_CYCLIN_yCln2_LP_2 267 273 PF00134 0.519
DOC_CYCLIN_yCln2_LP_2 401 407 PF00134 0.348
DOC_MAPK_DCC_7 149 157 PF00069 0.639
DOC_MAPK_DCC_7 757 765 PF00069 0.435
DOC_MAPK_gen_1 149 157 PF00069 0.545
DOC_MAPK_gen_1 65 72 PF00069 0.470
DOC_MAPK_gen_1 757 765 PF00069 0.435
DOC_MAPK_gen_1 847 855 PF00069 0.589
DOC_MAPK_HePTP_8 291 303 PF00069 0.546
DOC_MAPK_MEF2A_6 149 157 PF00069 0.639
DOC_MAPK_MEF2A_6 294 303 PF00069 0.539
DOC_MAPK_MEF2A_6 757 765 PF00069 0.435
DOC_MAPK_MEF2A_6 980 988 PF00069 0.464
DOC_PP2B_LxvP_1 267 270 PF13499 0.512
DOC_PP2B_LxvP_1 401 404 PF13499 0.377
DOC_PP2B_LxvP_1 474 477 PF13499 0.238
DOC_PP2B_LxvP_1 832 835 PF13499 0.416
DOC_PP4_FxxP_1 61 64 PF00568 0.519
DOC_SPAK_OSR1_1 645 649 PF12202 0.283
DOC_USP7_MATH_1 1061 1065 PF00917 0.669
DOC_USP7_MATH_1 14 18 PF00917 0.528
DOC_USP7_MATH_1 176 180 PF00917 0.679
DOC_USP7_MATH_1 248 252 PF00917 0.684
DOC_USP7_MATH_1 405 409 PF00917 0.295
DOC_USP7_MATH_1 575 579 PF00917 0.348
DOC_USP7_MATH_1 689 693 PF00917 0.403
DOC_USP7_MATH_1 734 738 PF00917 0.622
DOC_USP7_MATH_1 752 756 PF00917 0.530
DOC_USP7_MATH_1 796 800 PF00917 0.642
DOC_USP7_MATH_1 866 870 PF00917 0.401
DOC_USP7_MATH_1 872 876 PF00917 0.420
DOC_WW_Pin1_4 1059 1064 PF00397 0.554
DOC_WW_Pin1_4 148 153 PF00397 0.547
DOC_WW_Pin1_4 763 768 PF00397 0.608
DOC_WW_Pin1_4 802 807 PF00397 0.571
DOC_WW_Pin1_4 954 959 PF00397 0.591
DOC_WW_Pin1_4 969 974 PF00397 0.640
LIG_14-3-3_CanoR_1 1028 1038 PF00244 0.451
LIG_14-3-3_CanoR_1 1069 1078 PF00244 0.417
LIG_14-3-3_CanoR_1 169 178 PF00244 0.542
LIG_14-3-3_CanoR_1 3 11 PF00244 0.586
LIG_14-3-3_CanoR_1 35 44 PF00244 0.652
LIG_14-3-3_CanoR_1 377 383 PF00244 0.553
LIG_14-3-3_CanoR_1 391 398 PF00244 0.365
LIG_14-3-3_CanoR_1 428 438 PF00244 0.362
LIG_14-3-3_CanoR_1 453 457 PF00244 0.291
LIG_14-3-3_CanoR_1 65 71 PF00244 0.494
LIG_14-3-3_CanoR_1 673 683 PF00244 0.343
LIG_14-3-3_CanoR_1 746 751 PF00244 0.574
LIG_14-3-3_CanoR_1 818 823 PF00244 0.409
LIG_Actin_WH2_2 1014 1032 PF00022 0.477
LIG_Actin_WH2_2 1094 1111 PF00022 0.437
LIG_BIR_III_2 1060 1064 PF00653 0.507
LIG_BIR_III_2 175 179 PF00653 0.630
LIG_BIR_III_4 581 585 PF00653 0.304
LIG_BRCT_BRCA1_1 68 72 PF00533 0.603
LIG_BRCT_BRCA1_1 99 103 PF00533 0.442
LIG_Clathr_ClatBox_1 98 102 PF01394 0.526
LIG_deltaCOP1_diTrp_1 612 619 PF00928 0.348
LIG_FHA_1 134 140 PF00498 0.648
LIG_FHA_1 2 8 PF00498 0.496
LIG_FHA_1 266 272 PF00498 0.607
LIG_FHA_1 342 348 PF00498 0.569
LIG_FHA_1 683 689 PF00498 0.352
LIG_FHA_1 694 700 PF00498 0.643
LIG_FHA_1 713 719 PF00498 0.300
LIG_FHA_1 725 731 PF00498 0.528
LIG_FHA_1 751 757 PF00498 0.455
LIG_FHA_1 817 823 PF00498 0.434
LIG_FHA_1 94 100 PF00498 0.615
LIG_FHA_2 1072 1078 PF00498 0.382
LIG_FHA_2 1090 1096 PF00498 0.307
LIG_FHA_2 204 210 PF00498 0.669
LIG_FHA_2 362 368 PF00498 0.552
LIG_FHA_2 605 611 PF00498 0.252
LIG_FHA_2 787 793 PF00498 0.450
LIG_FHA_2 925 931 PF00498 0.752
LIG_Integrin_RGD_1 488 490 PF01839 0.217
LIG_LIR_Apic_2 60 64 PF02991 0.520
LIG_LIR_Apic_2 612 617 PF02991 0.348
LIG_LIR_Gen_1 1007 1013 PF02991 0.556
LIG_LIR_Gen_1 259 270 PF02991 0.549
LIG_LIR_Gen_1 455 462 PF02991 0.288
LIG_LIR_Gen_1 578 588 PF02991 0.335
LIG_LIR_Gen_1 716 724 PF02991 0.399
LIG_LIR_Nem_3 1007 1011 PF02991 0.563
LIG_LIR_Nem_3 259 265 PF02991 0.540
LIG_LIR_Nem_3 455 459 PF02991 0.288
LIG_LIR_Nem_3 578 583 PF02991 0.335
LIG_LIR_Nem_3 644 649 PF02991 0.283
LIG_LYPXL_SIV_4 441 449 PF13949 0.377
LIG_MLH1_MIPbox_1 68 72 PF16413 0.493
LIG_PDZ_Class_3 1107 1112 PF00595 0.440
LIG_Pex14_1 515 519 PF04695 0.377
LIG_REV1ctd_RIR_1 69 78 PF16727 0.499
LIG_RPA_C_Fungi 283 295 PF08784 0.524
LIG_SH2_CRK 193 197 PF00017 0.598
LIG_SH2_CRK 262 266 PF00017 0.559
LIG_SH2_CRK 398 402 PF00017 0.377
LIG_SH2_NCK_1 472 476 PF00017 0.412
LIG_SH2_PTP2 456 459 PF00017 0.317
LIG_SH2_SRC 785 788 PF00017 0.510
LIG_SH2_STAP1 260 264 PF00017 0.622
LIG_SH2_STAP1 472 476 PF00017 0.468
LIG_SH2_STAT3 836 839 PF00017 0.506
LIG_SH2_STAT5 159 162 PF00017 0.651
LIG_SH2_STAT5 193 196 PF00017 0.742
LIG_SH2_STAT5 300 303 PF00017 0.576
LIG_SH2_STAT5 442 445 PF00017 0.294
LIG_SH2_STAT5 456 459 PF00017 0.317
LIG_SH2_STAT5 519 522 PF00017 0.329
LIG_SH2_STAT5 816 819 PF00017 0.410
LIG_SH2_STAT5 836 839 PF00017 0.386
LIG_SH2_STAT5 878 881 PF00017 0.443
LIG_SH3_1 8 14 PF00018 0.522
LIG_SH3_3 157 163 PF00018 0.478
LIG_SH3_3 213 219 PF00018 0.567
LIG_SH3_3 296 302 PF00018 0.540
LIG_SH3_3 755 761 PF00018 0.559
LIG_SH3_3 8 14 PF00018 0.522
LIG_SUMO_SIM_par_1 45 50 PF11976 0.620
LIG_SUMO_SIM_par_1 685 692 PF11976 0.381
LIG_SUMO_SIM_par_1 771 777 PF11976 0.410
LIG_SUMO_SIM_par_1 89 96 PF11976 0.580
LIG_SUMO_SIM_par_1 97 102 PF11976 0.481
LIG_SUMO_SIM_par_1 980 985 PF11976 0.479
LIG_TRAF2_1 1093 1096 PF00917 0.453
LIG_TRAF2_1 329 332 PF00917 0.645
LIG_TRAF2_1 339 342 PF00917 0.349
LIG_TRAF2_1 944 947 PF00917 0.810
LIG_TYR_ITIM 396 401 PF00017 0.348
LIG_TYR_ITIM 454 459 PF00017 0.348
LIG_UBA3_1 372 378 PF00899 0.546
MOD_CDK_SPK_2 954 959 PF00069 0.550
MOD_CK1_1 1062 1068 PF00069 0.484
MOD_CK1_1 135 141 PF00069 0.630
MOD_CK1_1 15 21 PF00069 0.616
MOD_CK1_1 272 278 PF00069 0.604
MOD_CK1_1 480 486 PF00069 0.400
MOD_CK1_1 726 732 PF00069 0.629
MOD_CK1_1 788 794 PF00069 0.567
MOD_CK2_1 1071 1077 PF00069 0.387
MOD_CK2_1 1089 1095 PF00069 0.302
MOD_CK2_1 203 209 PF00069 0.630
MOD_CK2_1 277 283 PF00069 0.569
MOD_CK2_1 336 342 PF00069 0.460
MOD_CK2_1 361 367 PF00069 0.526
MOD_CK2_1 774 780 PF00069 0.469
MOD_Cter_Amidation 520 523 PF01082 0.389
MOD_GlcNHglycan 1089 1092 PF01048 0.475
MOD_GlcNHglycan 110 113 PF01048 0.571
MOD_GlcNHglycan 178 181 PF01048 0.712
MOD_GlcNHglycan 19 22 PF01048 0.591
MOD_GlcNHglycan 224 227 PF01048 0.690
MOD_GlcNHglycan 250 253 PF01048 0.761
MOD_GlcNHglycan 271 274 PF01048 0.665
MOD_GlcNHglycan 378 381 PF01048 0.615
MOD_GlcNHglycan 38 41 PF01048 0.543
MOD_GlcNHglycan 393 396 PF01048 0.377
MOD_GlcNHglycan 560 563 PF01048 0.427
MOD_GlcNHglycan 667 670 PF01048 0.348
MOD_GlcNHglycan 691 694 PF01048 0.470
MOD_GlcNHglycan 715 718 PF01048 0.505
MOD_GlcNHglycan 776 779 PF01048 0.467
MOD_GlcNHglycan 782 785 PF01048 0.511
MOD_GlcNHglycan 798 801 PF01048 0.657
MOD_GlcNHglycan 844 847 PF01048 0.762
MOD_GlcNHglycan 868 871 PF01048 0.394
MOD_GlcNHglycan 989 992 PF01048 0.651
MOD_GSK3_1 104 111 PF00069 0.478
MOD_GSK3_1 1067 1074 PF00069 0.618
MOD_GSK3_1 1085 1092 PF00069 0.408
MOD_GSK3_1 12 19 PF00069 0.685
MOD_GSK3_1 129 136 PF00069 0.672
MOD_GSK3_1 248 255 PF00069 0.662
MOD_GSK3_1 265 272 PF00069 0.753
MOD_GSK3_1 273 280 PF00069 0.716
MOD_GSK3_1 337 344 PF00069 0.510
MOD_GSK3_1 387 394 PF00069 0.614
MOD_GSK3_1 600 607 PF00069 0.225
MOD_GSK3_1 689 696 PF00069 0.516
MOD_GSK3_1 746 753 PF00069 0.530
MOD_GSK3_1 834 841 PF00069 0.632
MOD_GSK3_1 907 914 PF00069 0.680
MOD_GSK3_1 93 100 PF00069 0.652
MOD_GSK3_1 954 961 PF00069 0.727
MOD_GSK3_1 963 970 PF00069 0.608
MOD_GSK3_1 982 989 PF00069 0.510
MOD_N-GLC_1 810 815 PF02516 0.572
MOD_NEK2_1 1 6 PF00069 0.524
MOD_NEK2_1 1011 1016 PF00069 0.467
MOD_NEK2_1 1029 1034 PF00069 0.305
MOD_NEK2_1 108 113 PF00069 0.540
MOD_NEK2_1 203 208 PF00069 0.686
MOD_NEK2_1 254 259 PF00069 0.650
MOD_NEK2_1 303 308 PF00069 0.605
MOD_NEK2_1 376 381 PF00069 0.503
MOD_NEK2_1 429 434 PF00069 0.407
MOD_NEK2_1 47 52 PF00069 0.550
MOD_NEK2_1 496 501 PF00069 0.304
MOD_NEK2_1 604 609 PF00069 0.281
MOD_NEK2_1 683 688 PF00069 0.377
MOD_NEK2_1 724 729 PF00069 0.494
MOD_NEK2_1 986 991 PF00069 0.582
MOD_NEK2_2 104 109 PF00069 0.593
MOD_NEK2_2 1071 1076 PF00069 0.376
MOD_NEK2_2 600 605 PF00069 0.377
MOD_NEK2_2 752 757 PF00069 0.495
MOD_OFUCOSY 815 820 PF10250 0.434
MOD_PIKK_1 461 467 PF00454 0.339
MOD_PIKK_1 575 581 PF00454 0.217
MOD_PIKK_1 834 840 PF00454 0.562
MOD_PIKK_1 924 930 PF00454 0.737
MOD_PKA_1 1030 1036 PF00069 0.430
MOD_PKA_1 65 71 PF00069 0.534
MOD_PKA_1 746 752 PF00069 0.531
MOD_PKA_2 1029 1035 PF00069 0.492
MOD_PKA_2 1071 1077 PF00069 0.369
MOD_PKA_2 2 8 PF00069 0.777
MOD_PKA_2 376 382 PF00069 0.635
MOD_PKA_2 390 396 PF00069 0.349
MOD_PKA_2 452 458 PF00069 0.291
MOD_PKA_2 545 551 PF00069 0.377
MOD_PKA_2 604 610 PF00069 0.323
MOD_PKA_2 65 71 PF00069 0.535
MOD_PKA_2 745 751 PF00069 0.508
MOD_PKA_2 986 992 PF00069 0.524
MOD_PKB_1 1028 1036 PF00069 0.463
MOD_Plk_1 1009 1015 PF00069 0.405
MOD_Plk_1 203 209 PF00069 0.630
MOD_Plk_1 341 347 PF00069 0.475
MOD_Plk_1 361 367 PF00069 0.391
MOD_Plk_1 671 677 PF00069 0.283
MOD_Plk_2-3 963 969 PF00069 0.751
MOD_Plk_4 1037 1043 PF00069 0.498
MOD_Plk_4 137 143 PF00069 0.593
MOD_Plk_4 452 458 PF00069 0.316
MOD_Plk_4 545 551 PF00069 0.355
MOD_Plk_4 66 72 PF00069 0.493
MOD_Plk_4 683 689 PF00069 0.482
MOD_Plk_4 804 810 PF00069 0.506
MOD_ProDKin_1 1059 1065 PF00069 0.545
MOD_ProDKin_1 148 154 PF00069 0.547
MOD_ProDKin_1 763 769 PF00069 0.599
MOD_ProDKin_1 802 808 PF00069 0.567
MOD_ProDKin_1 954 960 PF00069 0.590
MOD_ProDKin_1 969 975 PF00069 0.631
MOD_SUMO_for_1 443 446 PF00179 0.377
MOD_SUMO_rev_2 946 952 PF00179 0.604
TRG_DiLeu_BaEn_1 368 373 PF01217 0.573
TRG_DiLeu_BaEn_1 545 550 PF01217 0.348
TRG_DiLeu_BaEn_3 1095 1101 PF01217 0.427
TRG_DiLeu_BaEn_3 341 347 PF01217 0.475
TRG_DiLeu_BaLyEn_6 654 659 PF01217 0.381
TRG_DiLeu_BaLyEn_6 86 91 PF01217 0.661
TRG_DiLeu_LyEn_5 368 373 PF01217 0.529
TRG_ENDOCYTIC_2 193 196 PF00928 0.600
TRG_ENDOCYTIC_2 262 265 PF00928 0.556
TRG_ENDOCYTIC_2 300 303 PF00928 0.576
TRG_ENDOCYTIC_2 398 401 PF00928 0.402
TRG_ENDOCYTIC_2 456 459 PF00928 0.317
TRG_ENDOCYTIC_2 719 722 PF00928 0.339
TRG_ER_diArg_1 1016 1019 PF00400 0.534
TRG_ER_diArg_1 1027 1030 PF00400 0.533
TRG_ER_diArg_1 1097 1100 PF00400 0.519
TRG_ER_diArg_1 33 36 PF00400 0.612
TRG_ER_diArg_1 352 354 PF00400 0.547
TRG_ER_diArg_1 381 383 PF00400 0.625
TRG_ER_diArg_1 484 487 PF00400 0.217
TRG_ER_diArg_1 522 524 PF00400 0.490
TRG_ER_diArg_1 64 66 PF00400 0.562
TRG_ER_diArg_1 7 10 PF00400 0.598
TRG_ER_diArg_1 756 759 PF00400 0.458
TRG_ER_diArg_1 847 850 PF00400 0.648
TRG_ER_diArg_1 852 855 PF00400 0.596
TRG_NES_CRM1_1 45 60 PF08389 0.538
TRG_Pf-PMV_PEXEL_1 616 620 PF00026 0.348
TRG_Pf-PMV_PEXEL_1 673 678 PF00026 0.254

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P5L8 Leptomonas seymouri 47% 100%
A0A1X0P2S1 Trypanosomatidae 29% 100%
A0A3S5H4W3 Leishmania donovani 88% 100%
A0A422NGS3 Trypanosoma rangeli 30% 100%
A4H397 Leishmania braziliensis 69% 99%
A4HRI7 Leishmania infantum 87% 100%
E9AJF1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS