Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AC53_LEIMA

TriTrypDb:

LmjF.01.0620 , LMJLV39_010011500 , LMJSD75_010011500

Length:

591

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AC53

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AC53

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	205	209	PF00656	0.387
CLV_NRD_NRD_1	282	284	PF00675	0.707
CLV_NRD_NRD_1	317	319	PF00675	0.608
CLV_NRD_NRD_1	336	338	PF00675	0.650
CLV_NRD_NRD_1	458	460	PF00675	0.693
CLV_NRD_NRD_1	483	485	PF00675	0.582
CLV_NRD_NRD_1	540	542	PF00675	0.572
CLV_PCSK_FUR_1	334	338	PF00082	0.659
CLV_PCSK_FUR_1	456	460	PF00082	0.696
CLV_PCSK_FUR_1	530	534	PF00082	0.493

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P577	Leptomonas seymouri	42%	93%
A0A451EJB6	Leishmania donovani	88%	99%
A4H333	Leishmania braziliensis	61%	96%
A4HRI5	Leishmania infantum	89%	100%
E9AJE9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	100%

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