40S ribosomal protein S7

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein S7, putative

Species:

Leishmania major

UniProt:

E9AC32_LEIMA

TriTrypDb:

LmjF.01.0420 , LMJLV39_010009400 , LMJSD75_010009400

Length:

200

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 12

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0015935	small ribosomal subunit	4	2
GO:0022627	cytosolic small ribosomal subunit	5	2
GO:0030684	preribosome	3	2
GO:0032040	small-subunit processome	4	2
GO:0032991	protein-containing complex	1	14
GO:0044391	ribosomal subunit	3	2
GO:0110165	cellular anatomical entity	1	14
GO:1990904	ribonucleoprotein complex	2	14
GO:0005840	ribosome	5	12
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12

Expansion

Sequence features

E9AC32

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AC32

PDB structure(s): 6az1_I

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006364	rRNA processing	8	2
GO:0006396	RNA processing	6	2
GO:0006412	translation	4	14
GO:0006518	peptide metabolic process	4	14
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	14
GO:0008152	metabolic process	1	14
GO:0009058	biosynthetic process	2	14
GO:0009059	macromolecule biosynthetic process	4	14
GO:0009987	cellular process	1	14
GO:0016070	RNA metabolic process	5	2
GO:0016072	rRNA metabolic process	7	2
GO:0019538	protein metabolic process	3	14
GO:0022613	ribonucleoprotein complex biogenesis	4	2
GO:0034470	ncRNA processing	7	2
GO:0034641	cellular nitrogen compound metabolic process	3	14
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	14
GO:0034660	ncRNA metabolic process	6	2
GO:0042274	ribosomal small subunit biogenesis	5	2
GO:0043043	peptide biosynthetic process	5	14
GO:0043170	macromolecule metabolic process	3	14
GO:0043603	amide metabolic process	3	14
GO:0043604	amide biosynthetic process	4	14
GO:0044085	cellular component biogenesis	3	2
GO:0044237	cellular metabolic process	2	14
GO:0044238	primary metabolic process	2	14
GO:0044249	cellular biosynthetic process	3	14
GO:0044260	obsolete cellular macromolecule metabolic process	3	14
GO:0044271	cellular nitrogen compound biosynthetic process	4	14
GO:0046483	heterocycle metabolic process	3	2
GO:0071704	organic substance metabolic process	2	14
GO:0071840	cellular component organization or biogenesis	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2
GO:1901564	organonitrogen compound metabolic process	3	14
GO:1901566	organonitrogen compound biosynthetic process	4	14
GO:1901576	organic substance biosynthetic process	3	14

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	14
GO:0005198	structural molecule activity	1	14

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	141	143	PF00675	0.308
CLV_NRD_NRD_1	161	163	PF00675	0.179
CLV_NRD_NRD_1	182	184	PF00675	0.396
CLV_NRD_NRD_1	5	7	PF00675	0.504
CLV_NRD_NRD_1	74	76	PF00675	0.325
CLV_NRD_NRD_1	8	10	PF00675	0.317
CLV_PCSK_KEX2_1	104	106	PF00082	0.308
CLV_PCSK_KEX2_1	12	14	PF00082	0.317
CLV_PCSK_KEX2_1	141	143	PF00082	0.308
CLV_PCSK_KEX2_1	163	165	PF00082	0.315
CLV_PCSK_KEX2_1	182	184	PF00082	0.315
CLV_PCSK_KEX2_1	87	89	PF00082	0.308
CLV_PCSK_PC1ET2_1	104	106	PF00082	0.308
CLV_PCSK_PC1ET2_1	12	14	PF00082	0.317
CLV_PCSK_PC1ET2_1	163	165	PF00082	0.326
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.308
CLV_PCSK_PC7_1	100	106	PF00082	0.308
CLV_PCSK_SKI1_1	100	104	PF00082	0.306
CLV_PCSK_SKI1_1	151	155	PF00082	0.317
CLV_PCSK_SKI1_1	177	181	PF00082	0.315
CLV_PCSK_SKI1_1	25	29	PF00082	0.317
CLV_PCSK_SKI1_1	50	54	PF00082	0.348
CLV_PCSK_SKI1_1	59	63	PF00082	0.331
CLV_PCSK_SKI1_1	79	83	PF00082	0.235
CLV_PCSK_SKI1_1	9	13	PF00082	0.317
CLV_Separin_Metazoa	40	44	PF03568	0.599
DEG_Nend_UBRbox_3	1	3	PF02207	0.672
DOC_CYCLIN_RxL_1	22	31	PF00134	0.528
DOC_MAPK_gen_1	53	63	PF00069	0.525
DOC_MAPK_MEF2A_6	56	65	PF00069	0.554
DOC_PP1_RVXF_1	180	187	PF00149	0.496
DOC_SPAK_OSR1_1	43	47	PF12202	0.517
DOC_USP7_MATH_1	80	84	PF00917	0.612
LIG_14-3-3_CanoR_1	117	125	PF00244	0.510
LIG_14-3-3_CanoR_1	144	153	PF00244	0.526
LIG_14-3-3_CanoR_1	182	187	PF00244	0.529
LIG_14-3-3_CanoR_1	56	62	PF00244	0.535
LIG_APCC_ABBA_1	153	158	PF00400	0.526
LIG_BRCT_BRCA1_1	184	188	PF00533	0.555
LIG_Clathr_ClatBox_1	27	31	PF01394	0.528
LIG_eIF4E_1	66	72	PF01652	0.510
LIG_FHA_1	58	64	PF00498	0.542
LIG_FHA_1	80	86	PF00498	0.508
LIG_FHA_2	46	52	PF00498	0.554
LIG_LIR_Gen_1	122	133	PF02991	0.576
LIG_LIR_LC3C_4	60	64	PF02991	0.537
LIG_LIR_Nem_3	122	128	PF02991	0.557
LIG_Pex14_2	186	190	PF04695	0.506
LIG_SH2_CRK	176	180	PF00017	0.515
LIG_SH2_STAT3	110	113	PF00017	0.508
LIG_SH2_STAT5	174	177	PF00017	0.598
LIG_SH3_3	49	55	PF00018	0.554
LIG_SH3_3	61	67	PF00018	0.489
LIG_SUMO_SIM_anti_2	60	65	PF11976	0.554
LIG_UBA3_1	27	35	PF00899	0.517
MOD_CK1_1	118	124	PF00069	0.508
MOD_CK1_1	33	39	PF00069	0.556
MOD_CK1_1	57	63	PF00069	0.599
MOD_CK2_1	14	20	PF00069	0.517
MOD_CK2_1	45	51	PF00069	0.612
MOD_CK2_1	80	86	PF00069	0.599
MOD_Cter_Amidation	139	142	PF01082	0.308
MOD_GSK3_1	100	107	PF00069	0.546
MOD_GSK3_1	115	122	PF00069	0.582
MOD_NEK2_1	19	24	PF00069	0.552
MOD_NEK2_1	30	35	PF00069	0.476
MOD_PKA_1	104	110	PF00069	0.513
MOD_PKA_1	182	188	PF00069	0.598
MOD_PKA_2	104	110	PF00069	0.525
MOD_PKA_2	182	188	PF00069	0.598
MOD_PKB_1	142	150	PF00069	0.515
MOD_PKB_1	162	170	PF00069	0.379
MOD_Plk_1	19	25	PF00069	0.542
MOD_Plk_4	57	63	PF00069	0.614
MOD_SUMO_rev_2	158	165	PF00179	0.515
TRG_ENDOCYTIC_2	176	179	PF00928	0.515
TRG_ER_diArg_1	141	143	PF00400	0.506
TRG_ER_diArg_1	162	165	PF00400	0.515
TRG_ER_diArg_1	182	184	PF00400	0.379
TRG_NLS_MonoExtC_3	11	16	PF00514	0.517
TRG_NLS_MonoExtC_3	5	10	PF00514	0.526
TRG_NLS_MonoExtN_4	3	10	PF00514	0.522
TRG_Pf-PMV_PEXEL_1	25	29	PF00026	0.328
TRG_Pf-PMV_PEXEL_1	79	84	PF00026	0.317

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PA77	Leptomonas seymouri	86%	100%
A0A0S4JIP7	Bodo saltans	73%	100%
A0A1X0P313	Trypanosomatidae	80%	99%
A0A3R7KMI4	Trypanosoma rangeli	81%	100%
A0A3R7KV77	Trypanosoma rangeli	78%	100%
A0A3R7M7D1	Trypanosoma rangeli	78%	99%
A0A3S7WNJ7	Leishmania donovani	98%	100%
A4H367	Leishmania braziliensis	91%	83%
A4H368	Leishmania braziliensis	91%	100%
A4HRG4	Leishmania infantum	98%	100%
A6H769	Bos taurus	36%	100%
C9ZXI9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	77%	99%
E9AJC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
O43105	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	39%	99%
P02362	Xenopus laevis	38%	100%
P26786	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	38%	100%
P33514	Anopheles gambiae	37%	100%
P48155	Manduca sexta	36%	100%
P48164	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	100%
P50894	Takifugu rubripes	36%	100%
P62081	Homo sapiens	36%	100%
P62082	Mus musculus	36%	100%
P62083	Rattus norvegicus	36%	100%
P62084	Danio rerio	37%	100%
P62085	Drosophila yakuba	38%	100%
Q10101	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	100%
Q23312	Caenorhabditis elegans	34%	100%
Q54I41	Dictyostelium discoideum	41%	100%
Q5AJ93	Candida albicans (strain SC5314 / ATCC MYA-2876)	38%	100%
Q5RT64	Felis catus	36%	100%
Q8LD03	Arabidopsis thaliana	37%	100%
Q8LJU5	Oryza sativa subsp. japonica	35%	100%
Q90YR7	Ictalurus punctatus	37%	100%
Q949H0	Hordeum vulgare	36%	100%
Q962S0	Spodoptera frugiperda	35%	100%
Q9C514	Arabidopsis thaliana	40%	100%
Q9M885	Arabidopsis thaliana	37%	100%
Q9NB21	Culex quinquefasciatus	36%	100%
Q9VA91	Drosophila melanogaster	39%	100%
Q9XET4	Secale cereale	34%	100%
Q9XH45	Brassica oleracea	36%	100%
Q9ZNS1	Avicennia marina	38%	100%