Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AC12_LEIMA

TriTrypDb:

LmjF.01.0230 , LMJLV39_010007200 , LMJSD75_010007300

Length:

138


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

E9AC12

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AC12


Leishmania	From	To	Domain/Motif	Score
CLV_Separin_Metazoa	77	81	PF03568	0.694
DEG_Nend_Nbox_1	1	3	PF02207	0.679
DOC_MAPK_MEF2A_6	3	10	PF00069	0.605
DOC_PP4_FxxP_1	62	65	PF00568	0.737
LIG_14-3-3_CanoR_1	120	124	PF00244	0.665
LIG_BRCT_BRCA1_1	47	51	PF00533	0.726
LIG_FHA_1	20	26	PF00498	0.615
LIG_FHA_2	68	74	PF00498	0.622
LIG_GBD_Chelix_1	71	79	PF00786	0.490
LIG_LIR_Apic_2	19	24	PF02991	0.601
LIG_LIR_Apic_2	61	65	PF02991	0.739
LIG_LIR_Nem_3	22	26	PF02991	0.589
LIG_LIR_Nem_3	48	54	PF02991	0.631
LIG_LYPXL_yS_3	23	26	PF13949	0.616
LIG_Pex14_1	58	62	PF04695	0.533
LIG_Pex14_2	51	55	PF04695	0.744
LIG_SH2_CRK	121	125	PF00017	0.607
LIG_SH2_CRK	21	25	PF00017	0.611
LIG_SH2_STAT5	110	113	PF00017	0.614
LIG_SH2_STAT5	21	24	PF00017	0.603
LIG_SUMO_SIM_anti_2	91	96	PF11976	0.618
MOD_CK1_1	105	111	PF00069	0.687
MOD_CK1_1	45	51	PF00069	0.631
MOD_CMANNOS	55	58	PF00535	0.536
MOD_GlcNHglycan	104	107	PF01048	0.562
MOD_GlcNHglycan	47	50	PF01048	0.606
MOD_GlcNHglycan	51	54	PF01048	0.578
MOD_GlcNHglycan	95	98	PF01048	0.688
MOD_GSK3_1	28	35	PF00069	0.684
MOD_GSK3_1	37	44	PF00069	0.627
MOD_GSK3_1	45	52	PF00069	0.632
MOD_GSK3_1	54	61	PF00069	0.677
MOD_N-GLC_1	129	134	PF02516	0.714
MOD_NEK2_1	1	6	PF00069	0.575
MOD_NEK2_1	102	107	PF00069	0.386
MOD_NEK2_1	16	21	PF00069	0.602
MOD_NEK2_1	54	59	PF00069	0.749
MOD_NEK2_1	78	83	PF00069	0.593
MOD_NEK2_1	90	95	PF00069	0.602
MOD_PIKK_1	16	22	PF00454	0.601
MOD_PKA_2	119	125	PF00069	0.706
MOD_PKB_1	127	135	PF00069	0.622
MOD_Plk_1	67	73	PF00069	0.626
MOD_Plk_4	105	111	PF00069	0.605
MOD_Plk_4	119	125	PF00069	0.566
MOD_Plk_4	90	96	PF00069	0.685
TRG_ENDOCYTIC_2	121	124	PF00928	0.605
TRG_ENDOCYTIC_2	23	26	PF00928	0.564
TRG_ENDOCYTIC_2	27	30	PF00928	0.571


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6P0	Leptomonas seymouri	51%	100%
A0A3S5H4T9	Leishmania donovani	91%	100%
A4H348	Leishmania braziliensis	74%	94%
E9AJA9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%