WGS CADB00000000 data, contig 72

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E8NHN7_LEIMU

TriTrypDb:

LmxM.32.3070partial

Length:

903

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E8NHN7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E8NHN7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	105	107	PF00675	0.564
CLV_NRD_NRD_1	114	116	PF00675	0.562
CLV_NRD_NRD_1	176	178	PF00675	0.584
CLV_NRD_NRD_1	335	337	PF00675	0.686
CLV_NRD_NRD_1	344	346	PF00675	0.605
CLV_NRD_NRD_1	406	408	PF00675	0.647
CLV_NRD_NRD_1	415	417	PF00675	0.706
CLV_NRD_NRD_1	477	479	PF00675	0.771
CLV_PCSK_KEX2_1	105	107	PF00082	0.564
CLV_PCSK_KEX2_1	114	116	PF00082	0.562
CLV_PCSK_KEX2_1	176	178	PF00082	0.584
CLV_PCSK_KEX2_1	335	337	PF00082	0.634
CLV_PCSK_KEX2_1	344	346	PF00082	0.578
CLV_PCSK_KEX2_1	406	408	PF00082	0.596
CLV_PCSK_KEX2_1	415	417	PF00082	0.655
CLV_PCSK_KEX2_1	477	479	PF00082	0.820
CLV_PCSK_SKI1_1	127	131	PF00082	0.532
CLV_PCSK_SKI1_1	234	238	PF00082	0.399
CLV_PCSK_SKI1_1	357	361	PF00082	0.628
CLV_PCSK_SKI1_1	4	8	PF00082	0.494
CLV_PCSK_SKI1_1	428	432	PF00082	0.682
CLV_PCSK_SKI1_1	535	539	PF00082	0.364
DEG_SCF_FBW7_1	107	113	PF00400	0.557
DEG_SCF_FBW7_1	337	343	PF00400	0.586
DEG_SCF_FBW7_1	408	414	PF00400	0.589
DOC_CKS1_1	107	112	PF01111	0.559
DOC_CKS1_1	128	133	PF01111	0.527
DOC_CKS1_1	178	183	PF01111	0.568
DOC_CKS1_1	337	342	PF01111	0.588
DOC_CKS1_1	358	363	PF01111	0.554
DOC_CKS1_1	408	413	PF01111	0.593
DOC_CKS1_1	429	434	PF01111	0.556
DOC_CKS1_1	479	484	PF01111	0.571
DOC_CYCLIN_RxL_1	158	169	PF00134	0.517
DOC_CYCLIN_RxL_1	317	328	PF00134	0.565
DOC_CYCLIN_RxL_1	388	399	PF00134	0.561
DOC_CYCLIN_RxL_1	459	470	PF00134	0.560
DOC_CYCLIN_RxL_1	87	98	PF00134	0.527
DOC_PP2B_LxvP_1	613	616	PF13499	0.549
DOC_PP2B_LxvP_1	670	673	PF13499	0.555
DOC_PP2B_LxvP_1	727	730	PF13499	0.559
DOC_PP2B_LxvP_1	784	787	PF13499	0.562
DOC_PP2B_LxvP_1	841	844	PF13499	0.553
DOC_PP2B_LxvP_1	898	901	PF13499	0.548
DOC_USP7_MATH_1	110	114	PF00917	0.556
DOC_USP7_MATH_1	340	344	PF00917	0.575
DOC_USP7_MATH_1	411	415	PF00917	0.606
DOC_USP7_MATH_1	641	645	PF00917	0.551
DOC_USP7_MATH_1	698	702	PF00917	0.549
DOC_USP7_MATH_1	755	759	PF00917	0.559
DOC_USP7_MATH_1	812	816	PF00917	0.559
DOC_USP7_MATH_1	869	873	PF00917	0.556
DOC_WW_Pin1_4	106	111	PF00397	0.560
DOC_WW_Pin1_4	127	132	PF00397	0.556
DOC_WW_Pin1_4	177	182	PF00397	0.727
DOC_WW_Pin1_4	262	267	PF00397	0.392
DOC_WW_Pin1_4	280	285	PF00397	0.467
DOC_WW_Pin1_4	286	291	PF00397	0.551
DOC_WW_Pin1_4	32	37	PF00397	0.445
DOC_WW_Pin1_4	336	341	PF00397	0.775
DOC_WW_Pin1_4	357	362	PF00397	0.559
DOC_WW_Pin1_4	407	412	PF00397	0.593
DOC_WW_Pin1_4	428	433	PF00397	0.560
DOC_WW_Pin1_4	478	483	PF00397	0.578
DOC_WW_Pin1_4	50	55	PF00397	0.551
DOC_WW_Pin1_4	56	61	PF00397	0.571
DOC_WW_Pin1_4	563	568	PF00397	0.359
DOC_WW_Pin1_4	581	586	PF00397	0.463
DOC_WW_Pin1_4	587	592	PF00397	0.512
LIG_14-3-3_CanoR_1	234	243	PF00244	0.383
LIG_14-3-3_CanoR_1	4	13	PF00244	0.471
LIG_14-3-3_CanoR_1	535	544	PF00244	0.349
LIG_14-3-3_CanoR_1	634	643	PF00244	0.562
LIG_14-3-3_CanoR_1	691	700	PF00244	0.567
LIG_14-3-3_CanoR_1	748	757	PF00244	0.569
LIG_14-3-3_CanoR_1	805	814	PF00244	0.567
LIG_14-3-3_CanoR_1	862	871	PF00244	0.567
LIG_BIR_II_1	1	4	PF00653	0.450
LIG_BIR_III_4	223	227	PF00653	0.366
LIG_BIR_III_4	524	528	PF00653	0.403
LIG_BRCT_BRCA1_1	137	141	PF00533	0.532
LIG_BRCT_BRCA1_1	367	371	PF00533	0.542
LIG_BRCT_BRCA1_1	438	442	PF00533	0.560
LIG_BRCT_BRCA1_1	597	601	PF00533	0.523
LIG_deltaCOP1_diTrp_1	200	209	PF00928	0.380
LIG_deltaCOP1_diTrp_1	501	510	PF00928	0.380
LIG_FHA_1	118	124	PF00498	0.586
LIG_FHA_1	216	222	PF00498	0.362
LIG_FHA_1	268	274	PF00498	0.372
LIG_FHA_1	348	354	PF00498	0.591
LIG_FHA_1	38	44	PF00498	0.453
LIG_FHA_1	419	425	PF00498	0.593
LIG_FHA_1	517	523	PF00498	0.362
LIG_FHA_1	569	575	PF00498	0.336
LIG_FHA_2	107	113	PF00498	0.802
LIG_FHA_2	164	170	PF00498	0.532
LIG_FHA_2	178	184	PF00498	0.538
LIG_FHA_2	323	329	PF00498	0.567
LIG_FHA_2	337	343	PF00498	0.535
LIG_FHA_2	394	400	PF00498	0.598
LIG_FHA_2	408	414	PF00498	0.538
LIG_FHA_2	465	471	PF00498	0.558
LIG_FHA_2	479	485	PF00498	0.516
LIG_FHA_2	93	99	PF00498	0.562
LIG_LIR_Gen_1	138	149	PF02991	0.552
LIG_LIR_Gen_1	298	308	PF02991	0.766
LIG_LIR_Gen_1	368	379	PF02991	0.547
LIG_LIR_Gen_1	439	450	PF02991	0.789
LIG_LIR_Gen_1	598	609	PF02991	0.522
LIG_LIR_Gen_1	646	654	PF02991	0.535
LIG_LIR_Gen_1	68	78	PF02991	0.556
LIG_LIR_Gen_1	703	711	PF02991	0.537
LIG_LIR_Gen_1	760	768	PF02991	0.545
LIG_LIR_Gen_1	817	825	PF02991	0.548
LIG_LIR_Gen_1	874	882	PF02991	0.551
LIG_LIR_Nem_3	138	144	PF02991	0.555
LIG_LIR_Nem_3	200	205	PF02991	0.615
LIG_LIR_Nem_3	207	212	PF02991	0.528
LIG_LIR_Nem_3	268	274	PF02991	0.419
LIG_LIR_Nem_3	298	303	PF02991	0.765
LIG_LIR_Nem_3	368	374	PF02991	0.541
LIG_LIR_Nem_3	38	44	PF02991	0.457
LIG_LIR_Nem_3	439	445	PF02991	0.789
LIG_LIR_Nem_3	501	506	PF02991	0.370
LIG_LIR_Nem_3	508	513	PF02991	0.374
LIG_LIR_Nem_3	569	575	PF02991	0.336
LIG_LIR_Nem_3	598	604	PF02991	0.517
LIG_LIR_Nem_3	646	651	PF02991	0.541
LIG_LIR_Nem_3	68	73	PF02991	0.560
LIG_LIR_Nem_3	703	708	PF02991	0.546
LIG_LIR_Nem_3	760	765	PF02991	0.552
LIG_LIR_Nem_3	817	822	PF02991	0.555
LIG_LIR_Nem_3	874	879	PF02991	0.556
LIG_Pex14_2	267	271	PF04695	0.573
LIG_Pex14_2	37	41	PF04695	0.461
LIG_Pex14_2	568	572	PF04695	0.337
LIG_PTB_Apo_2	261	268	PF02174	0.397
LIG_PTB_Apo_2	31	38	PF02174	0.448
LIG_PTB_Apo_2	562	569	PF02174	0.363
LIG_Rb_LxCxE_1	658	677	PF01857	0.553
LIG_Rb_LxCxE_1	715	734	PF01857	0.553
LIG_Rb_LxCxE_1	772	791	PF01857	0.561
LIG_Rb_LxCxE_1	829	848	PF01857	0.552
LIG_Rb_LxCxE_1	886	903	PF01857	0.553
LIG_SH2_NCK_1	274	278	PF00017	0.404
LIG_SH2_NCK_1	44	48	PF00017	0.478
LIG_SH2_NCK_1	575	579	PF00017	0.371
LIG_SH2_STAP1	274	278	PF00017	0.404
LIG_SH2_STAP1	44	48	PF00017	0.478
LIG_SH2_STAP1	575	579	PF00017	0.371
LIG_SH3_3	104	110	PF00018	0.555
LIG_SH3_3	125	131	PF00018	0.586
LIG_SH3_3	144	150	PF00018	0.548
LIG_SH3_3	175	181	PF00018	0.577
LIG_SH3_3	303	309	PF00018	0.547
LIG_SH3_3	334	340	PF00018	0.590
LIG_SH3_3	355	361	PF00018	0.833
LIG_SH3_3	374	380	PF00018	0.549
LIG_SH3_3	405	411	PF00018	0.588
LIG_SH3_3	426	432	PF00018	0.573
LIG_SH3_3	445	451	PF00018	0.480
LIG_SH3_3	476	482	PF00018	0.749
LIG_SH3_3	604	610	PF00018	0.525
LIG_SH3_3	648	654	PF00018	0.537
LIG_SH3_3	705	711	PF00018	0.540
LIG_SH3_3	73	79	PF00018	0.553
LIG_SH3_3	762	768	PF00018	0.548
LIG_SH3_3	819	825	PF00018	0.551
LIG_SH3_3	876	882	PF00018	0.551
LIG_TRAF2_1	109	112	PF00917	0.557
LIG_TRAF2_1	155	158	PF00917	0.512
LIG_TRAF2_1	167	170	PF00917	0.500
LIG_TRAF2_1	180	183	PF00917	0.505
LIG_TRAF2_1	314	317	PF00917	0.562
LIG_TRAF2_1	326	329	PF00917	0.525
LIG_TRAF2_1	339	342	PF00917	0.532
LIG_TRAF2_1	385	388	PF00917	0.553
LIG_TRAF2_1	397	400	PF00917	0.513
LIG_TRAF2_1	410	413	PF00917	0.541
LIG_TRAF2_1	456	459	PF00917	0.550
LIG_TRAF2_1	468	471	PF00917	0.555
LIG_TRAF2_1	481	484	PF00917	0.519
LIG_TRAF2_1	84	87	PF00917	0.522
LIG_TRAF2_1	96	99	PF00917	0.602
MOD_CDK_SPxxK_3	262	269	PF00069	0.394
MOD_CDK_SPxxK_3	280	287	PF00069	0.481
MOD_CDK_SPxxK_3	32	39	PF00069	0.451
MOD_CDK_SPxxK_3	50	57	PF00069	0.561
MOD_CDK_SPxxK_3	563	570	PF00069	0.361
MOD_CK1_1	140	146	PF00069	0.593
MOD_CK1_1	265	271	PF00069	0.379
MOD_CK1_1	299	305	PF00069	0.561
MOD_CK1_1	35	41	PF00069	0.471
MOD_CK1_1	370	376	PF00069	0.541
MOD_CK1_1	441	447	PF00069	0.564
MOD_CK1_1	566	572	PF00069	0.344
MOD_CK1_1	600	606	PF00069	0.519
MOD_CK1_1	69	75	PF00069	0.647
MOD_CK2_1	106	112	PF00069	0.613
MOD_CK2_1	163	169	PF00069	0.533
MOD_CK2_1	177	183	PF00069	0.545
MOD_CK2_1	322	328	PF00069	0.568
MOD_CK2_1	336	342	PF00069	0.538
MOD_CK2_1	393	399	PF00069	0.600
MOD_CK2_1	407	413	PF00069	0.541
MOD_CK2_1	464	470	PF00069	0.560
MOD_CK2_1	478	484	PF00069	0.524
MOD_CK2_1	647	653	PF00069	0.541
MOD_CK2_1	704	710	PF00069	0.548
MOD_CK2_1	761	767	PF00069	0.552
MOD_CK2_1	818	824	PF00069	0.552
MOD_CK2_1	875	881	PF00069	0.557
MOD_CK2_1	92	98	PF00069	0.744
MOD_DYRK1A_RPxSP_1	106	110	PF00069	0.556
MOD_DYRK1A_RPxSP_1	127	131	PF00069	0.532
MOD_DYRK1A_RPxSP_1	177	181	PF00069	0.575
MOD_DYRK1A_RPxSP_1	336	340	PF00069	0.591
MOD_DYRK1A_RPxSP_1	357	361	PF00069	0.567
MOD_DYRK1A_RPxSP_1	407	411	PF00069	0.591
MOD_DYRK1A_RPxSP_1	428	432	PF00069	0.566
MOD_DYRK1A_RPxSP_1	478	482	PF00069	0.580
MOD_GlcNHglycan	637	640	PF01048	0.566
MOD_GlcNHglycan	694	697	PF01048	0.571
MOD_GlcNHglycan	751	754	PF01048	0.574
MOD_GlcNHglycan	808	811	PF01048	0.568
MOD_GlcNHglycan	865	868	PF01048	0.566
MOD_GSK3_1	106	113	PF00069	0.559
MOD_GSK3_1	336	343	PF00069	0.588
MOD_GSK3_1	407	414	PF00069	0.590
MOD_NEK2_1	118	123	PF00069	0.582
MOD_NEK2_1	16	21	PF00069	0.444
MOD_NEK2_1	188	193	PF00069	0.418
MOD_NEK2_1	235	240	PF00069	0.395
MOD_NEK2_1	246	251	PF00069	0.321
MOD_NEK2_1	267	272	PF00069	0.370
MOD_NEK2_1	348	353	PF00069	0.590
MOD_NEK2_1	37	42	PF00069	0.474
MOD_NEK2_1	419	424	PF00069	0.708
MOD_NEK2_1	489	494	PF00069	0.547
MOD_NEK2_1	5	10	PF00069	0.483
MOD_NEK2_1	536	541	PF00069	0.361
MOD_NEK2_1	547	552	PF00069	0.300
MOD_NEK2_1	568	573	PF00069	0.334
MOD_NEK2_1	647	652	PF00069	0.544
MOD_NEK2_1	704	709	PF00069	0.550
MOD_NEK2_1	761	766	PF00069	0.555
MOD_NEK2_1	818	823	PF00069	0.555
MOD_NEK2_1	875	880	PF00069	0.557
MOD_PKA_2	135	141	PF00069	0.545
MOD_PKA_2	365	371	PF00069	0.549
MOD_PKA_2	436	442	PF00069	0.562
MOD_PKA_2	641	647	PF00069	0.573
MOD_PKA_2	698	704	PF00069	0.543
MOD_PKA_2	755	761	PF00069	0.551
MOD_PKA_2	812	818	PF00069	0.554
MOD_PKA_2	869	875	PF00069	0.554
MOD_Plk_1	118	124	PF00069	0.560
MOD_Plk_1	348	354	PF00069	0.591
MOD_Plk_1	419	425	PF00069	0.593
MOD_Plk_4	119	125	PF00069	0.559
MOD_Plk_4	238	244	PF00069	0.364
MOD_Plk_4	349	355	PF00069	0.591
MOD_Plk_4	420	426	PF00069	0.593
MOD_Plk_4	539	545	PF00069	0.331
MOD_Plk_4	8	14	PF00069	0.481
MOD_ProDKin_1	106	112	PF00069	0.560
MOD_ProDKin_1	127	133	PF00069	0.557
MOD_ProDKin_1	177	183	PF00069	0.726
MOD_ProDKin_1	262	268	PF00069	0.395
MOD_ProDKin_1	280	286	PF00069	0.475
MOD_ProDKin_1	32	38	PF00069	0.447
MOD_ProDKin_1	336	342	PF00069	0.772
MOD_ProDKin_1	357	363	PF00069	0.561
MOD_ProDKin_1	407	413	PF00069	0.593
MOD_ProDKin_1	428	434	PF00069	0.561
MOD_ProDKin_1	478	484	PF00069	0.575
MOD_ProDKin_1	50	56	PF00069	0.555
MOD_ProDKin_1	563	569	PF00069	0.361
MOD_ProDKin_1	581	587	PF00069	0.470
MOD_SUMO_rev_2	275	283	PF00179	0.491
MOD_SUMO_rev_2	45	53	PF00179	0.508
MOD_SUMO_rev_2	576	584	PF00179	0.429
TRG_DiLeu_BaEn_1	208	213	PF01217	0.384
TRG_DiLeu_BaEn_1	509	514	PF01217	0.382
TRG_DiLeu_BaEn_4	170	176	PF01217	0.531
TRG_DiLeu_BaEn_4	329	335	PF01217	0.570
TRG_DiLeu_BaEn_4	400	406	PF01217	0.564
TRG_DiLeu_BaEn_4	471	477	PF01217	0.564
TRG_DiLeu_BaEn_4	99	105	PF01217	0.534
TRG_ENDOCYTIC_2	274	277	PF00928	0.400
TRG_ENDOCYTIC_2	44	47	PF00928	0.478
TRG_ENDOCYTIC_2	575	578	PF00928	0.365
TRG_ER_diArg_1	104	106	PF00400	0.562
TRG_ER_diArg_1	175	177	PF00400	0.585
TRG_ER_diArg_1	194	197	PF00400	0.391
TRG_ER_diArg_1	334	336	PF00400	0.628
TRG_ER_diArg_1	405	407	PF00400	0.616
TRG_ER_diArg_1	476	478	PF00400	0.590
TRG_ER_diArg_1	495	498	PF00400	0.296
TRG_Pf-PMV_PEXEL_1	645	649	PF00026	0.540
TRG_Pf-PMV_PEXEL_1	702	706	PF00026	0.544
TRG_Pf-PMV_PEXEL_1	759	763	PF00026	0.550
TRG_Pf-PMV_PEXEL_1	816	820	PF00026	0.554
TRG_Pf-PMV_PEXEL_1	873	877	PF00026	0.558

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9B4E7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	100%