Guanine nucleotide-binding protein subunit beta-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E8NHN3_LEIMU

TriTrypDb:

LmxM.28.2750partial

Length:

122

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0015935	small ribosomal subunit	4	2
GO:0032991	protein-containing complex	1	2
GO:0044391	ribosomal subunit	3	2
GO:1990904	ribonucleoprotein complex	2	2

Expansion

Sequence features

E8NHN3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E8NHN3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0043021	ribonucleoprotein complex binding	3	2
GO:0043022	ribosome binding	4	2
GO:0044877	protein-containing complex binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	32	36	PF00656	0.700
CLV_NRD_NRD_1	100	102	PF00675	0.500
CLV_PCSK_SKI1_1	101	105	PF00082	0.500
CLV_PCSK_SKI1_1	108	112	PF00082	0.412
DEG_Nend_UBRbox_3	1	3	PF02207	0.845
DEG_SPOP_SBC_1	29	33	PF00917	0.700
DOC_MAPK_gen_1	105	115	PF00069	0.700
DOC_MAPK_MEF2A_6	108	115	PF00069	0.700
DOC_WW_Pin1_4	113	118	PF00397	0.700
LIG_14-3-3_CanoR_1	11	20	PF00244	0.700
LIG_14-3-3_CanoR_1	47	51	PF00244	0.791
LIG_FHA_1	105	111	PF00498	0.700
LIG_FHA_1	63	69	PF00498	0.700
LIG_FHA_2	30	36	PF00498	0.700
LIG_LIR_Apic_2	51	57	PF02991	0.754
LIG_LIR_Gen_1	25	30	PF02991	0.700
LIG_LIR_Nem_3	25	29	PF02991	0.700
LIG_RPA_C_Fungi	6	18	PF08784	0.600
LIG_SH2_CRK	54	58	PF00017	0.729
LIG_SH2_PTP2	26	29	PF00017	0.600
LIG_SH2_STAP1	79	83	PF00017	0.600
LIG_SH2_STAT5	26	29	PF00017	0.600
MOD_CDK_SPxxK_3	113	120	PF00069	0.600
MOD_CK1_1	49	55	PF00069	0.768
MOD_CK1_1	69	75	PF00069	0.250
MOD_GSK3_1	30	37	PF00069	0.600
MOD_GSK3_1	62	69	PF00069	0.600
MOD_GSK3_1	81	88	PF00069	0.267
MOD_NEK2_2	85	90	PF00069	0.600
MOD_PKA_2	46	52	PF00069	0.783
MOD_Plk_1	85	91	PF00069	0.600
MOD_Plk_2-3	46	52	PF00069	0.783
MOD_Plk_4	22	28	PF00069	0.600
MOD_ProDKin_1	113	119	PF00069	0.600
TRG_DiLeu_BaLyEn_6	117	122	PF01217	0.600
TRG_ENDOCYTIC_2	26	29	PF00928	0.600

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0CH87	PARTE	33%	30%
A0DB19	PARTE	33%	30%
A8X8C6	CAEBR	37%	33%
G4MQX3	MAGO7	44%	39%
O18640	DROME	46%	38%
O24076	MEDSA	42%	38%
O24456	ARATH	44%	37%
O42248	DANRE	47%	38%
O42249	ORENI	44%	38%
O43017	SCHPO	33%	32%
O45040	HOMAM	30%	36%
O54929	MOUSE	31%	30%
P11017	BOVIN	30%	36%
P16520	HUMAN	32%	36%
P17343	CAEEL	31%	36%
P25387	CHLRE	40%	38%
P26308	DROME	31%	36%
P36408	DICDI	30%	35%
P38011	YEAST	40%	38%
P46800	DICDI	41%	37%
P49026	TOBAC	42%	37%
P49027	ORYSJ	42%	37%
P49178	MAIZE	30%	32%
P52287	RAT	33%	36%
P54311	RAT	31%	36%
P54313	RAT	30%	36%
P61964	HUMAN	28%	37%
P61965	MOUSE	28%	37%
P62871	BOVIN	31%	36%
P62872	CANLF	31%	36%
P62873	HUMAN	31%	36%
P62874	MOUSE	31%	36%
P62879	HUMAN	30%	36%
P62880	MOUSE	30%	36%
P62883	LEICH	100%	39%
P62884	LEIIN	100%	39%
P63243	BOVIN	47%	38%
P63244	HUMAN	47%	38%
P63245	RAT	47%	38%
P63246	PIG	47%	38%
P63247	CHICK	47%	38%
P68040	MOUSE	47%	38%
P69103	TRYBB	66%	38%
P69104	TRYBR	66%	38%
P79147	CANLF	32%	36%
P79959	XENLA	29%	36%
P83774	CANAL	41%	38%
P93340	NICPL	43%	37%
Q01369	NEUCR	43%	39%
Q08706	LYMST	40%	36%
Q0V8J1	BOVIN	31%	30%
Q10281	SCHPO	45%	39%
Q17963	CAEEL	34%	32%
Q21215	CAEEL	42%	38%
Q25189	HYDVU	46%	38%
Q25306	LEIMA	98%	39%
Q2KIG2	BOVIN	28%	37%
Q39336	BRANA	44%	37%
Q39836	SOYBN	42%	38%
Q498M4	RAT	28%	37%
Q4R7Y4	MACFA	47%	38%
Q54KL5	DICDI	27%	36%
Q5DFU0	SCHJA	34%	35%
Q5GIS3	PINFU	40%	36%
Q5M786	XENTR	28%	37%
Q5R5W8	PONAB	31%	36%
Q5RE95	PONAB	26%	37%
Q61011	MOUSE	33%	36%
Q61ZF6	CAEBR	31%	36%
Q6L4F8	ORYSJ	41%	36%
Q6PH57	DANRE	31%	36%
Q6TMK6	CRIGR	31%	36%
Q86TI4	HUMAN	30%	32%
Q86VZ2	HUMAN	26%	37%
Q8W1K8	CHLRE	32%	33%
Q93134	BIOGL	47%	39%
Q9C4Z6	ARATH	41%	37%
Q9D7H2	MOUSE	26%	37%
Q9FKT5	ARATH	33%	39%
Q9HAV0	HUMAN	27%	36%
Q9JHB4	MOUSE	28%	33%
Q9LV28	ARATH	43%	37%
Q9M2Z2	ARATH	28%	38%
Q9NYS7	HUMAN	31%	30%
Q9SY00	ARATH	35%	37%
Q9V3J8	DROME	35%	34%